Section | Jotup

Aquestive Therapeutics to Present Positive Data from Pharmacokinetic and Pharmacodynamic Studies for Anaphylm™ at American College of Allergy Asthma and Immunology (ACAAI) Annual Meeting

Retrieved on:

Friday, November 10, 2023

Therapy, Section, Patient, American College, Adrenaline, ACAAI, Pharmaceutical industry

WARREN, N.J., Nov. 10, 2023 (GLOBE NEWSWIRE) -- Aquestive Therapeutics, Inc. (NASDAQ: AQST) (the “Company” or “Aquestive”), a pharmaceutical company advancing medicines to bring meaningful improvement to patients' lives through innovative science and delivery technologies, today announced that two posters recapping the positive data from pharmacokinetic (PK) and pharmacodynamic (PD) pre-clinical and clinical studies of Anaphylm™ (epinephrine) Sublingual Film will be presented at the American College of Allergy Asthma and Immunology (ACAAI) annual meeting, which will be held from November 9-13 in Anaheim, California.

Key Points:

WARREN, N.J., Nov. 10, 2023 (GLOBE NEWSWIRE) -- Aquestive Therapeutics, Inc. (NASDAQ: AQST) (the “Company” or “Aquestive”), a pharmaceutical company advancing medicines to bring meaningful improvement to patients' lives through innovative science and delivery technologies, today announced that two posters recapping the positive data from pharmacokinetic (PK) and pharmacodynamic (PD) pre-clinical and clinical studies of Anaphylm™ (epinephrine) Sublingual Film will be presented at the American College of Allergy Asthma and Immunology (ACAAI) annual meeting, which will be held from November 9-13 in Anaheim, California.
“We are thrilled to have a significant presence at ACAAI this year and are excited to share the positive results from our completed Anaphylm pharmacokinetic and pharmacodynamic studies with leaders in the allergy community,” said Dan Barber, Aquestive’s President and Chief Executive Officer.
“These positive results are encouraging as we continue to evaluate the potential of Anaphylm and its ability to provide an important advancement for the treatment of acute allergic reactions, if approved by the FDA.”
Location: ePoster Section - Exhibit Hall, Monitor 11
Poster Title: Epinephrine Administered via Sublingual Film, Manual Injection, or Auto-Injectors in Healthy Adults: Pharmacodynamic Results
Location: ePoster Section - Exhibit Hall, Monitor 11

Vertex and CRISPR Therapeutics Announce US FDA Approval of CASGEVY™ (exagamglogene autotemcel) for the Treatment of Sickle Cell Disease

Retrieved on:

Friday, December 8, 2023

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and CRISPR Therapeutics (Nasdaq: CRSP) announced today that the U.S. Food and Drug Administration (FDA) has approved CASGEVY™ (exagamglogene autotemcel [exa-cel]), a CRISPR/Cas9 genome-edited cell therapy, for the treatment of sickle cell disease (SCD) in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

Key Points:

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and CRISPR Therapeutics (Nasdaq: CRSP) announced today that the U.S. Food and Drug Administration (FDA) has approved CASGEVY™ (exagamglogene autotemcel [exa-cel]), a CRISPR/Cas9 genome-edited cell therapy, for the treatment of sickle cell disease (SCD) in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).
“CASGEVY’s approval by the FDA is momentous: it is the first CRISPR-based gene-editing therapy to be approved in the U.S. As importantly, CASGEVY is a first-in-class treatment that offers the potential of a one-time transformative therapy for eligible patients with sickle cell disease,” said Reshma Kewalramani, M.D., Chief Executive Officer and President of Vertex.
So, this U.S. approval of the first-ever medicine using CRISPR gene editing is breathtaking, and a truly humbling moment for me personally and for the whole organization,” said Samarth Kulkarni, Ph.D., Chairman and Chief Executive Officer of CRISPR Therapeutics.
The following ATCs are already activated:
Boston Medical Center in Boston, Mass.

Press Conference: Hundreds of transplant patients, physicians, and health equity advocates expected to rally on Capitol Hill on Tuesday, December 5 to ask President Joe Biden and HHS Secretary Xavier Becerra: "Urgently intervene! Stop private contractors

Retrieved on:

Wednesday, November 29, 2023

Policy, Transplant, Maryland School, Section, Patient, Transplant surgeon, Fear, Health, University, MD, MPH, Medicare, Administration, Physician, Biopsy, Dentistry, Pharmaceutical industry, Medicine

WASHINGTON, Nov. 29, 2023 /PRNewswire/ -- Honor the Gift, a coalition representing organ transplant patients across the nation, will be joined by Representative Don Bacon (R-NE), the American Association of Kidney Patient's (AAKP) Chair of Policy and Global Affairs Paul T. Conway, Al B Sure!, Executive Chairman of the newly formed "Health Equity in Transplantation Coalition," Rev. Al Sharpton, Senior Advisor, and other leaders in the transplant field, to hold a press conference on December 5, 2023 in the Cannon Caucus Room on Capitol Hill in Washington D.C.

Key Points:

University of Maryland School of Medicine
In March, transplant patients' regular care was disrupted when a private contractor of Medicare called "MolDX" came between them and their trusted doctors and published an "Article" which tied coverage of non-invasive blood tests to invasive biopsies.
The alternative for such blood tests is surgical biopsy procedures, which are more expensive, riskier, and burdensome.
For years, transplant doctors could rely on their medical expertise and advanced blood tests to monitor organ transplant injury or rejection, safeguarding patients from invasive biopsies.
Now, as Medicare reviews the comments and determines the final decision on coverage, the transplant community is fearful their voices have been ignored and are making a public plea to the Administration.

NEVADA KING INTERCEPTS 2.37 G/T AU OVER 75M AT A DEPTH OF JUST 12M BENEATH THE ATLANTA PIT, EXTENDS THE 'EAST HIGH-GRADE ZONE' NORTHWARD

Retrieved on:

Wednesday, November 29, 2023

EAF, Section, Uranium mining

Mineralization occurs along sub-horizontal horizons generally dipping gently westward; true mineralized thickness in vertical holes is estimated to be between 85% and 95% of reported vertical drill intercept length.

Key Points:

Mineralization occurs along sub-horizontal horizons generally dipping gently westward; true mineralized thickness in vertical holes is estimated to be between 85% and 95% of reported vertical drill intercept length.
The East High-Grade Zone had previously been intercepted in holes drilled south of Section 22-10N(3) and today's intercept successfully extends this zone 30m northward, injecting higher-grade and thicker mineralization into this area of the AMFZ.
AT23NS-120 intercepted 1.14 g/t Au over 38.1m and was positioned 17m north-northwest of AT23NS-124 to define the western boundary of the East High-Grade Zone.
Today's 75m thick intercept averaging 2.37 g/t Au in AT23NS-124 is the thickest intercept recorded to date along the East High-Grade Zone."

The Nation's Largest Resource for Affordable Housing Bans Hidden Rental Fees

Retrieved on:

Thursday, November 16, 2023

Well, Pest control, Pet, Public housing, Section 8, White, Fraud, History, Section, BOCA, Advertising, Tenant, Housing, Communication, Publishing, Government, Lease

BOCA RATON, Fla., Nov. 16, 2023 /PRNewswire/ -- AffordableHousing.com, the largest resource for affordable housing in the US, today announced that, effective immediately, all rental listings on the site will be required to divulge any additional fees upfront. The move comes as part of the company's commitment to help protect renters from unfair practices and undisclosed fees that often drive up the cost of a rental well beyond the listed price.

Key Points:

BOCA RATON, Fla., Nov. 16, 2023 /PRNewswire/ -- AffordableHousing.com, the largest resource for affordable housing in the US, today announced that, effective immediately, all rental listings on the site will be required to divulge any additional fees upfront.
Affordable Housing Bans hidden rental fees to protect consumers, in coordination with White House initiative.
Each month, over 4 million Americans search for a new rental home on AffordableHousing.com.
Earlier this year, the White House called on three of the largest online platforms for housing to join its initiative to end junk fees for the purpose of protecting consumers.

NEVADA KING HITS MULTIPLE +80M INTERVALS OF HIGH-GRADE GOLD/SILVER MINERALIZATION AT ATLANTA INCLUDING 6.55 G/T AU AND 100.8 G/T AG OVER 82.3M

Retrieved on:

Tuesday, November 14, 2023

Bobcat, Economics, Gold, Section, Section 22, Bonanza, Barrow-in-Furness Higher Grade School, EAF, Telescopic sight, Printed circuit board, Uranium mining, Atlanta, Gustafson

*Denotes 45 o angle hole with true

Key Points:

*Denotes 45 o angle hole with true
mineralized thicknesses in angle holes estimated to be 65% to 70% of reported drill intercept length.
Note, AT23NS-133F is hosted along the east side of the West Atlanta Fault, whereas AT23WS-44 is located 200m to the northwest along the West Atlanta Fault #1 – a different structure.
Of all the holes hosting elevated high-grade intercepts, only AT23NS-133F occurs proximal to other holes hosting similar grades.
The very high-grade intercept in AT23NS-133F also exerted a strong influence on Nevada King's average grade.

StorageVault to Acquire Four Locations for $75.7 Million

Retrieved on:

Monday, November 6, 2023

Sale, Minority, Mergers and acquisitions, MI, Section, Vendor, CANADA, Acquisition, Access, Related party transaction, Hand, Fair market value, TSX, Commercial property, Risk management

TORONTO, Nov. 06, 2023 (GLOBE NEWSWIRE) -- STORAGEVAULT CANADA INC. (“StorageVault”) (SVI-TSX) has agreed to acquire four locations from four vendor groups (collectively, the “Vendors”) for an aggregate purchase price of $75,685,000, subject to customary adjustments (the “Acquisitions”).

Key Points:

TORONTO, Nov. 06, 2023 (GLOBE NEWSWIRE) -- STORAGEVAULT CANADA INC. (“StorageVault”) (SVI-TSX) has agreed to acquire four locations from four vendor groups (collectively, the “Vendors”) for an aggregate purchase price of $75,685,000, subject to customary adjustments (the “Acquisitions”).
Three of the Acquisitions are arm’s length and one for $45,000,000 is a related party acquisition (the “Related Party Acquisition”) with Access Self Storage Inc. (“Access”) as the Vendor for that Acquisition.
As Access is a non-arm’s length party to StorageVault, the Related Party Acquisition is considered a “related party transaction” under MI 61-101 - “Protection of Minority Security Holders in Special Transactions” (“MI 61-101”).
No new insiders will be created, nor will any change of control occur, as a result of the ‎Acquisitions.

Guggenheim Investments Announces November 2023 Closed-End Fund Distributions

Retrieved on:

Wednesday, November 1, 2023

Policy, Section, Depository Trust & Clearing Corporation, FICC, Life insurance

Final determination of the character of distributions will be made at year-end.

Key Points:

Final determination of the character of distributions will be made at year-end.
Distributions may be paid from sources of income other than ordinary income, such as short-term capital gains, long-term capital gains or return of capital.
Unless otherwise noted, the distributions above are not anticipated to include a return of capital.
The final determination of the source and tax characteristics of all distributions will be made after the end of the year.

NEVADA KING INTERCEPTS 4.96 G/T AU OVER 27.4M AND 2.33 G/T OVER 74.7M FURTHER DEFINING HIGH-GRADE MINERALIZATION ACROSS THE ATLANTA MINE FAULT ZONE AND THE WEST ATLANTA GRABEN ZONE

Retrieved on:

Monday, October 30, 2023

Section, AKF, WAF, Printed circuit board, Road, Atlanta

*Denotes 45o angle hole with true

Key Points:

*Denotes 45o angle hole with true
mineralized thicknesses in angle hole estimated to be 65% to 70% of reported drill intercept length.
4.96 g/t Au over 27.4m in AT23NS-70 is hosted within silicified breccia and adjacent porphyritic rhyolitic breccia dikes/sills.
Higher Au-Ag grades are frequently found in the silica breccia proximal to these tuff dikes further north and south along the Atlanta King Fault ("AKF").
If this drilling is successful, it will open up an entirely new frontier that has never been previously explored."

Webscale Acquires Section.io to Launch CloudFlow: An AI-Based Platform For Smart Distributed Computing and Cloud Cost Control

Retrieved on:

Thursday, October 19, 2023

CloudFlow empowers businesses, from Independent Software Vendors (ISVs) to enterprise organizations, to harness the full potential of AI to drive deep levels of efficiency into their distributed cloud computing strategies.

Key Points:

CloudFlow empowers businesses, from Independent Software Vendors (ISVs) to enterprise organizations, to harness the full potential of AI to drive deep levels of efficiency into their distributed cloud computing strategies.
Zero-Ops Simplicity: By utilizing CloudFlow, zero-ops distributed cloud computing becomes an immediate reality, saving organizations time, effort, and resources.
"The acquisition of Section.io by Webscale signifies a pivotal moment in cloud-native computing," said Gary Schofield, CEO of Webscale.
Under the united Webscale banner, we're poised to redefine the future of digital experiences, setting new standards for smart distributed computing and cloud infrastructure cost control.