Polio

I2Pure Hires Healthcare Industry Leader as Chief Executive Officer

Retrieved on: 
Tuesday, November 7, 2023
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Today, I2Pure announced the hiring of its new Chief Executive Officer, Jeffrey Jochims, effective November 1, 2023.

Key Points: 
  • Today, I2Pure announced the hiring of its new Chief Executive Officer, Jeffrey Jochims, effective November 1, 2023.
  • We’re elated to have someone of Jeff’s experience and capabilities join our company as Chief Executive Officer,” said Doug Spitz, I2Pure Founder.
  • We’re humbled and proud that I2Pure has been able to attract and retain an executive leader of Jeff’s caliber.
  • About I2Pure: I2Pure is a healthcare technology company dedicated to advancing the world of health and biosafety by preventing infections and disease through its patented, non-toxic molecular iodine platform.

Sabin Vaccine Institute Begins Phase 2 Clinical Trial for Marburg Vaccine in Uganda

Retrieved on: 
Thursday, October 19, 2023
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WASHINGTON, Oct. 19, 2023 (GLOBE NEWSWIRE) -- The Sabin Vaccine Institute has launched a Phase 2 clinical trial for its vaccine candidate against the lethal Marburg virus. Healthy volunteers received the single-dose vaccine at Makerere University Walter Reed Project (MUWRP) in Kampala, Uganda today.

Key Points: 
  • WASHINGTON, Oct. 19, 2023 (GLOBE NEWSWIRE) -- The Sabin Vaccine Institute has launched a Phase 2 clinical trial for its vaccine candidate against the lethal Marburg virus.
  • “Makerere University Walter Reed Project (MUWRP) is delighted to partner with the Sabin Vaccine Institute to launch the clinical testing for a preventive Marburg vaccine,” says Dr. Mwesigwa.
  • In addition to the current trial in Uganda and Kenya, Sabin plans to conduct a similar Phase 2 clinical trial for Marburg in the U.S.
  • Sabin has also initiated plans for a Phase 2 Sudan ebolavirus vaccine clinical trial in Uganda and Kenya.

PharmaJet, Nigeria’s National Primary Health Care Development Agency, and Health-focused Consortium Begin Implementation of Study Using Tropis® ID for Routine Immunization

Retrieved on: 
Tuesday, October 24, 2023
General Health, Infectious Diseases, Health, Pharmaceutical, Medical Supplies, Vaccine hesitancy, Government, Policy, Peritonitis, International development, Vaccine, Polio, Global Polio Eradication Initiative, Use, Injection, Multimedia, Criticism of the United States government, USAID, IPV, Syringe, Jhpiego, Immunization, United, PATH

Partners are also evaluating the acceptability and feasibility of using needle-free from the healthcare worker and caregiver perspective.

Key Points: 
  • Partners are also evaluating the acceptability and feasibility of using needle-free from the healthcare worker and caregiver perspective.
  • View the full release here: https://www.businesswire.com/news/home/20231024060890/en/
    Nigerian baby receiving polio vaccine with the PharmaJet Tropis® Precision Needle-free System.
  • Evidence from the study is intended to inform policy regarding intradermal delivery of polio vaccine in routine immunization settings.
  • Study preparation included the development of standard operating procedures to ensure congruence with the country’s existing medical guidelines.

With COVID now endemic, modelling suggests targeted protection will be more effective than blanket measures

Retrieved on: 
Wednesday, August 23, 2023
People, Vaccine, Infection, Omicron, Prevalence, Vaccination, SARS-CoV-2, Public, COVID-19, Season, Immunity, COVID, Clinical epidemiology, Reproduction, Government, Measles, Death, Incidence, Polio, Population, Time, Risk, WHO, Eris, Disease, Pharmaceutical industry, Birth control

In New Zealand, the government removed all remaining public health measures last week.

Key Points: 
  • In New Zealand, the government removed all remaining public health measures last week.
  • But although the emergency is over and the disease is rapidly becoming endemic, the risk of new variants remains.

The basic reproduction number

    • Back in 2020, we heard a lot about the basic reproduction number or R0.
    • This is the average number of people someone infects when the whole population is susceptible to the disease.
    • With a susceptible population, if R0 is above 1 the disease spreads exponentially.
    • This situation prompted governments around the world to implement intensive response measures, including lockdowns, to prevent health systems from becoming completely overwhelmed.

Controlling the disease

    • Effective control measures should reduce the number of contacts infectious people have, or the risk of infection per contact.
    • That’s certainly true, but how much effect do control measures realistically have for a virus like SARS-CoV-2?
    • But the effective reproduction number – the average number of people someone infects at the present time – is much closer to 1.

The maths of immunity

    • People may have acquired immunity through vaccination, but the protection vaccines provide against infection with current Omicron variants is relatively low and short-lived.
    • The majority of immunity comes from previous infections, including infections in vaccinated people.
    • (This doesn’t mean that getting infected to get immunity should ever be a goal, but it is an important side effect).
    • If R0=10, the maths is even more dismal: the same control measure only gives a 3% reduction in infections.

Targeted protection

    • The susceptible-immune binary is a simplification because immunity is not black and white but shades of grey.
    • Interventions targeted towards vulnerable groups are likely to be more effective than blanket measures.
    • Importantly, although reducing infection rates in the long term is difficult, vaccines provide direct protection for those who take them and continue to be highly effective at preventing severe disease.
    • He is an invited expert member of the Communicable Disease Network of Australia and between January 2020 and May 2022 was an invited expert member of the Australian Health Protection Principal Committee.

Orchard Therapeutics Strongly Supports Enactment of Newborn Metabolic Screening Act in Illinois, Adding Metachromatic Leukodystrophy to Statewide Panel

Retrieved on: 
Wednesday, August 2, 2023
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Illinois becomes the first state in the U.S. to add newborn screening for MLD to its statewide panel.

Key Points: 
  • Illinois becomes the first state in the U.S. to add newborn screening for MLD to its statewide panel.
  • “The enactment of SB67 represents the culmination of a multi-stakeholder initiative working together to expand screening for MLD and represents a significant milestone for newborn screening in the U.S.,” said Leslie Meltzer, Ph.D., chief medical officer of Orchard Therapeutics.
  • In addition to SB67, the company is supporting several newborn screening initiatives, including:
    Nine prospective newborn screening studies are active throughout Europe, the U.S. and the Middle East.
  • In Germany, following the positive identification of three newborns with MLD from a prospective study, progress has been made toward an application for nationwide screening.

ROYAL CANADIAN MINT ISSUES A NEW $1 CIRCULATION COIN HONOURING ENGINEER, WOMEN'S RIGHTS CHAMPION AND "QUEEN OF THE HURRICANES" ELSIE MACGILL

Retrieved on: 
Tuesday, August 1, 2023
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CALGARY, AB, Aug. 1, 2023 /CNW/ - The Royal Canadian Mint is issuing a new $1 commemorative circulation coin honouring Elsie MacGill, an exceptional Canadian who broke barriers as an engineer and leading advocate of women's rights.

Key Points: 
  • CALGARY, AB, Aug. 1, 2023 /CNW/ - The Royal Canadian Mint is issuing a new $1 commemorative circulation coin honouring Elsie MacGill, an exceptional Canadian who broke barriers as an engineer and leading advocate of women's rights.
  • Her lifelong advocacy for women's rights included her appointment to the Royal Commission on the Status of Women, in 1967.
  • "Inspiring Canadians through stories of exceptional achievement is one of the most important functions of commemorative circulation coins," said Marie Lemay, P.
  • The artwork appearing on the reverse of the 2023 $1 circulation coin celebrating Elsie MacGill is the creation of Tofino, British Columbia artist Claire Watson.

ROYAL CANADIAN MINT ISSUES A NEW $1 CIRCULATION COIN HONOURING ENGINEER, WOMEN'S RIGHTS CHAMPION AND "QUEEN OF THE HURRICANES" ELSIE MACGILL

Retrieved on: 
Tuesday, August 1, 2023
Hawker Hurricane, Music, Royal Canadian Mint, Bachelor, University, University of Michigan, Education, Life, Mint, Politics, CCF Maple Leaf Trainer II, Aviation, AB, Canadian Car and Foundry, Business, Tropical cyclone, Elizabeth II, Women's rights, Second, Polio, Canada Post, Royal commission, Engineering, Master, Maple leaf, Royal Commission on the Status of Women, Aerospace engineering, Glass, Electricity, Nursing, Interior design, Cryptocurrency, Palladium, Woman

CALGARY, AB, Aug. 1, 2023 /CNW/ - The Royal Canadian Mint is issuing a new $1 commemorative circulation coin honouring Elsie MacGill, an exceptional Canadian who broke barriers as an engineer and leading advocate of women's rights.

Key Points: 
  • CALGARY, AB, Aug. 1, 2023 /CNW/ - The Royal Canadian Mint is issuing a new $1 commemorative circulation coin honouring Elsie MacGill, an exceptional Canadian who broke barriers as an engineer and leading advocate of women's rights.
  • Her lifelong advocacy for women's rights included her appointment to the Royal Commission on the Status of Women, in 1967.
  • "Inspiring Canadians through stories of exceptional achievement is one of the most important functions of commemorative circulation coins," said Marie Lemay, P.
  • The artwork appearing on the reverse of the 2023 $1 circulation coin celebrating Elsie MacGill is the creation of Tofino, British Columbia artist Claire Watson.

WHO Launching Polio Eradication Campaign in Pakistan Using PharmaJet Precision Delivery System

Retrieved on: 
Tuesday, May 23, 2023
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PharmaJet ®, a company engineering precision delivery systems that overcome the challenges of vaccine delivery, today announced their support for the World Health Organization’s (WHO) polio eradication campaigns in Pakistan starting in May 2023.

Key Points: 
  • PharmaJet ®, a company engineering precision delivery systems that overcome the challenges of vaccine delivery, today announced their support for the World Health Organization’s (WHO) polio eradication campaigns in Pakistan starting in May 2023.
  • The PharmaJet Tropis Precision Delivery System™ (PDS) was selected based on its proven cost savings, ease of training, and improved immunization coverage benefits.
  • The WHO previously introduced needle-free intradermal delivery of inactivated polio vaccine (ID-IPV) in Pakistan and Somalia using the PharmaJet Tropis ID PDS for the immunization of millions of children.
  • “Very much like COVID, as long as we have polio transmission anywhere, potentially everywhere is at risk.

Learning from COVID-19: The global health emergency has ended. Here's what is needed to prepare for the next one

Retrieved on: 
Sunday, May 14, 2023
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However, it would be a mistake to assume that this is a mere formality.

Key Points: 
  • However, it would be a mistake to assume that this is a mere formality.
  • A PHEIC, like the one adopted for COVID-19 on Jan. 30, 2020, is declared if a public health event is determined to constitute:
  • A PHEIC means the WHO is sounding the loudest possible alarm to national governments to act together with urgency.
  • However, the heightened state of emergency under a PHEIC is not meant to be sustained indefinitely.

Significance of the end of the COVID-19 PHEIC

    • Moreover, the phrase “no one is safe until everyone is safe” may have become a familiar tagline during the pandemic.
    • Yet, many people, mostly in low- and middle-income countries, still struggle to access COVID-19 vaccines, diagnostics and treatments.
    • Second, the standing down of the PHEIC declaration is accompanied by an understandable desire — and necessity — to “move on” from COVID-19 after three difficult years.
    • The lack of real-world authority by the WHO to enforce the legally binding IHR has become abundantly clear.

Global co-ordination fell short

    • Still, what ensued fell far short of a co-ordinated global effort.
    • Read more:
      COVID-19 vaccine inequity allowed Omicron to emerge

      The need for collective action during global public health emergencies like COVID-19 has only been reinforced by the past three years.

    • Additionally, travel measures implemented in response to COVID-19, and in previous PHEICs, fell inequitably upon different population groups.
    • Meanwhile, a new pandemic may already be on the horizon as the global and interspecies spread of highly pathogenic avian influenza is raising growing alarm.

'Got polio?' messaging underscores a vaccine campaign's success but creates false sense of security as memories of the disease fade in US

Retrieved on: 
Friday, April 28, 2023
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Thanks, Science.” Messages like this are used in memes, posters, T-shirts and even some billboards to promote routine vaccinations.

Key Points: 
  • Thanks, Science.” Messages like this are used in memes, posters, T-shirts and even some billboards to promote routine vaccinations.
  • Phrasing that aims to encourage immunizations by highlighting their accomplishments implies that some diseases are no longer a threat.
  • Moreover, a 2020 poll had found that 84% of adults viewed vaccinating children as important, a 10% decline from 2001.
  • A shift in focus to immunization in developing countries has further lulled Americans into a false sense of security.

Campaigning against a devastating disease

    • Before vaccines, polio – called infantile paralysis or poliomyelitis – was the most feared childhood disease in the U.S.
    • Frequently affecting elementary school kids, the disease sometimes presented like a cold or flu – fever, sore throat and headache.
    • Only time could reveal whether the paralysis was permanent or would recede, sometimes to return decades later as Post-Polio Syndrome.
    • High schoolers performed polio-themed plays, putting the disease itself on trial in “The People vs. Polio.” People passed around collection boxes at movie theaters and other public gatherings.

From public enemy No. 1 to success story

    • Over the next decade, the NFIP shifted its focus to widespread immunization, again using both mass media and local campaigns.
    • The repeated declaration of what polio vaccines could and were accomplishing was strategically effective in persuading more people to get their shots.
    • The American public of the 1960s and 1970s had lived through repeated polio epidemics and knew both the fear of contracting the disease and its visible aftereffects.
    • Public health rhetoric that focused on this vaccine success story worked around the world in the late 1980s and 1990s.
    • A reminder for the American public about this still dangerous disease can help ensure that “Got Polio?” does not become a serious question.