SCC

In Novel Cohort, New Data Confirms DecisionDx®-SCC Provides Significant, Independent and Clinically Actionable Risk-Stratification of Patients, Including in Various High-Risk Subgroups

Retrieved on: 
Thursday, March 7, 2024

“Incorporating DecisionDx-SCC test results into the management of high-risk SCC can help ensure patients receive the best care possible by incorporating their biological risk of metastasis into the treatment plan.

Key Points: 
  • “Incorporating DecisionDx-SCC test results into the management of high-risk SCC can help ensure patients receive the best care possible by incorporating their biological risk of metastasis into the treatment plan.
  • DecisionDx-SCC also provided significant and clinically actionable risk stratification in various patient subgroups, including NCCN high and very high-risk, lower-stage BWH tumors and Medicare-eligible patients, further stratifying risk to help guide important treatment decisions for these patients.
  • These data support the use of DecisionDx-SCC test results, informed by a patient’s tumor biology, to guide personalized patient treatment decisions aligned to a patient’s risk of metastasis over three years.
  • “As such, we continue to develop evidence showing that our test adds independent prognostic value to the clinical and pathologic risk factors used for guiding risk-informed treatment plans within current guidelines.

Fujirebio Europe Expands Its Portfolio With Introduction of the Innovative PreCursor-M AnoGYN assay (RUO) for Methylation Testing in Anal Specimens

Retrieved on: 
Tuesday, March 5, 2024

Also in this HPV-related cancer, methylation appears to be promising for future use as an accurate biomarker for objective risk stratification of anal lesions.

Key Points: 
  • Also in this HPV-related cancer, methylation appears to be promising for future use as an accurate biomarker for objective risk stratification of anal lesions.
  • In analogy with cervical cancer screening, the screening and treatment of HSIL to prevent anal cancer in high-risk groups are under debate.
  • Host cell deoxyribonucleic acid methylation markers for the detection of high-grade anal intraepithelial neoplasia and anal cancer.
  • Analytical validation and diagnostic performance of the ASCL1/ZNF582 methylation test for detection of high-grade anal intraepithelial neoplasia and anal cancer.

Castle Biosciences Reports Fourth Quarter and Full-Year 2023 Results

Retrieved on: 
Wednesday, February 28, 2024

Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced its financial results for the fourth quarter and year ended Dec. 31, 2023.

Key Points: 
  • Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced its financial results for the fourth quarter and year ended Dec. 31, 2023.
  • DecisionDx-SCC test reports delivered in the quarter were 3,530, compared to 1,845 in the fourth quarter of 2022, an increase of 91%.
  • DecisionDx-UM test reports delivered in the quarter were 405, compared to 432 in the fourth quarter of 2022, a decrease of 6%.
  • Castle Biosciences will hold a conference call on Wednesday, Feb. 28, 2024, at 4:30 p.m. Eastern time to discuss its fourth quarter and full-year 2023 results and provide a corporate update.

Lincoln Property Company, BPGbio, and Cresa Announce 70,000-sq.-ft. Lease at 300 Third Avenue in Waltham

Retrieved on: 
Wednesday, February 21, 2024

ft. of lab and office space at 300 Third Avenue in Waltham, Mass.

Key Points: 
  • ft. of lab and office space at 300 Third Avenue in Waltham, Mass.
  • View the full release here: https://www.businesswire.com/news/home/20240221278304/en/
    300 Third Avenue in Waltham, Massachusetts.
  • 300 Third Avenue is a 143,533-sq.-ft. purpose-built life science building with four stories of laboratory space and 441 on-site parking spaces.
  • Lincoln Property Company (“Lincoln”) is one of the largest diversified real estate services companies with 35 offices across the United States the United Kingdom and Europe.

Supreme Court dismisses Secure Energy's application to appeal the successful challenge of Secure and Tervita merger

Retrieved on: 
Monday, February 26, 2024

GATINEAU, QC, Feb. 26, 2024 /CNW/ - The Competition Bureau welcomes the Supreme Court of Canada's (SCC) decision to dismiss an application by Secure Energy seeking leave to appeal the Bureau's successful challenge of the merger of two rival suppliers of oilfield waste services.

Key Points: 
  • GATINEAU, QC, Feb. 26, 2024 /CNW/ - The Competition Bureau welcomes the Supreme Court of Canada's (SCC) decision to dismiss an application by Secure Energy seeking leave to appeal the Bureau's successful challenge of the merger of two rival suppliers of oilfield waste services.
  • The Bureau recently approved R360 Environmental Solutions Canada Inc. as the buyer of the 29 facilities.
  • The facilities include 17 treatment, recovery, and disposal facilities, 4 standalone water disposal wells, 6 landfills and 2 caverns.
  • Secure acquired these facilities as part of the merger.

Dominion Energy Successfully Concludes Noncontrolling Equity Partner Process for Coastal Virginia Offshore Wind Commercial Project; Announces Highly Credit-Positive Transaction Featuring Robust Cost- and Risk-Sharing With High-Quality and Well-Capitalized

Retrieved on: 
Thursday, February 22, 2024

Under the terms of the agreement, Dominion Energy will retain full operational control of the construction and operations of CVOW.

Key Points: 
  • Under the terms of the agreement, Dominion Energy will retain full operational control of the construction and operations of CVOW.
  • Robert M. Blue, Dominion Energy chair, president and chief executive officer, said:
    "The Coastal Virginia Offshore Wind project continues to proceed on-time and on-budget and consistent with our previously communicated timing and cost expectations.
  • We have reviewed the transaction with our credit-rating agencies and expect the transaction to be viewed as a significant credit-positive, which will ultimately benefit our customers.
  • Dominion Energy management believes FFO-to-debt provides a more meaningful representation of the company's ability to service its debt obligations.

Medical Journal: Image-Guided Superficial Radiation Therapy Is Superior to Superficial Radiation Therapy Without Guidance

Retrieved on: 
Tuesday, February 20, 2024

BURR RIDGE, Ill., Feb. 20, 2024 /PRNewswire/ -- SkinCure Oncology, the world leader in providing a comprehensive model for the delivery of Image-Guided Superficial Radiation Therapy (Image-Guided SRT or IGSRT) for the treatment of nonmelanoma skin cancer, presented to dermatology patients as the GentleCure™ experience, announced the publication of research, "Image guidance improves freedom from recurrence in superficial radiation therapy for non-melanoma skin cancer," in Advances in Radiation Oncology, a peer-reviewed journal from the American Society for Radiation Oncology (ASTRO).

Key Points: 
  • It shows definitively that the new technology is superior, and represents a seminal moment in the care of skin cancer patients using radiation.
  • This study is the first to rigorously compare SRT to IGSRT, and it covers all the data that exists on IGSRT.
  • Superficial radiation therapy was developed over 100 years ago ( here ) and was the standard therapy for nonmelanoma skin cancer until Mohs micrographic surgery emerged in the 1930's ( here ).
  • IGSRT and the GentleCure experience will be showcased at the upcoming American Academy of Dermatology annual meeting in San Diego, at booth 3555.

Redesigned for the modern family: The 2025 Kia Carnival to debut at the Canadian International Auto Show

Retrieved on: 
Monday, February 12, 2024

This refreshed model strikes the balance of utility, purpose, and modern luxury, and with no detail overlooked, it will now become available in a hybrid powertrain.

Key Points: 
  • This refreshed model strikes the balance of utility, purpose, and modern luxury, and with no detail overlooked, it will now become available in a hybrid powertrain.
  • "The 2025 Carnival elevates the standard in its segment, emphasizing both function and luxuriousness in harmony," says David Sherrard, Director of Strategic Planning at Kia Canada.
  • The Carnival and Carnival Hybrid usher in a dynamic and eco-friendly option to the full-size family vehicle segment.
  • The gas version of the Carnival is expected to arrive in dealerships this Spring, and Carnival Hybrid arriving this summer.

NEW 2025 KIA K5 MAKES NORTH AMERICAN DEBUT AT CHICAGO AUTO SHOW

Retrieved on: 
Thursday, February 8, 2024

IRVINE, Calif., Feb. 8, 2024 /PRNewswire/ -- Kia America chose the concrete corridors of Chicago to pull the wraps off the refreshed 2025 K5 midsize sedan today at the opening of the Chicago Auto Show. The show played host to the sporty sedan's North American debut, which features a new-for-K5 2.5-liter normally aspirated engine, updated design cues inside and out, drivetrain refinements and numerous tech upgrades across five trim levels: LXS, EX, GT-Line (in front or all-wheel drive) and the hot-blooded turbocharged GT.

Key Points: 
  • The updates for 2025 position the K5 in the sweet spot for those needing room for five but prefer to make a bold statement when it comes to their vehicle."
  • For the 2025 model year, subtle refinements highlight more standard features across the lineup with a focus on the popular EX trim.
  • Digital Key 22, heated steering wheel, and power folding mirrors with integrated LED turn signals are all standard.
  • Already a standout in the midsize sedan segment, the 2025 Kia K5's design enhancements better align with Kia's Opposites United typography.

CoreView Doubles Down on Channel and MSP Investment and Increases Channel Sales 300%

Retrieved on: 
Tuesday, February 6, 2024

CoreView , the #1 Microsoft 365 management platform, announced today that it increased channel sales by 300% in 2023 and continues to invest in its Channel and MSP programs.

Key Points: 
  • CoreView , the #1 Microsoft 365 management platform, announced today that it increased channel sales by 300% in 2023 and continues to invest in its Channel and MSP programs.
  • The company has launched a new partner program and has added key executives to support its Channel and MSP partners.
  • Last year, CoreView made significant investments in its channel strategy and made firm commitments to channel partners on the MSP and Reseller side, pledging to be 100% channel-focused.
  • The company appointed Jennifer Phillips as the VP of Strategic Sales, Channel, and Alliances and hired Ellan Murphy, an SVP with a track record of developing successful MSP go-to-market strategies.