New Mechanism of Action Data for NT219 Presented at Epigenetics and Metabolism AACR Special Virtual Conference
The data was generated as part of the Companys collaboration with Professor Ido Wolf, Head of the Oncology Division, Tel Aviv Sourasky Medical Center.
- The data was generated as part of the Companys collaboration with Professor Ido Wolf, Head of the Oncology Division, Tel Aviv Sourasky Medical Center.
- The new data demonstrates IRS2-amplified colorectal cancer (CRC) cells upregulate -catenin expression, and treatment with NT219 significantly decreased the -catenin transcriptional activity in these cells.
- -catenin signaling by Wnt has been shown to have a number of different cellular influences.
- We expect top-line data from the first part of this important study in the second half of 2021.