Penn Dental Medicine Study Finds a Combined Treatment that Could Take a Bite Out of Tooth Decay
This dual dilemma becomes particularly pronounced in high-risk populations where the onset of the disease can be both rapid and severe.
- This dual dilemma becomes particularly pronounced in high-risk populations where the onset of the disease can be both rapid and severe.
- Now, a study from a team of researchers led by Penn Dental Medicine's Hyun (Michel) Koo in collaboration with David Cormode of Penn's Perelman School of Medicine and School of Engineering and Applied Science has unveiled an unexpected synergy in the battle against dental caries.
- Their research revealed that combining stannous fluoride (SnF2) – the fluoride routinely used in dental care products – with ferumoxytol (Fer), an off-the-shelf iron oxide nanoparticle formulation, could point to a potent solution against dental caries.
- "Traditional treatments often come short in managing the complex biofilm environment in the mouth," says Koo, senior co-author on the study.