Composition of electronic cigarette aerosol

NIH Awards $2.3 Million to The Lundquist Institute to Study the Impact of Vaping While Pregnant

Retrieved on: 
Monday, August 3, 2020

Investigators from The Lundquist Institute, under the leadership of Virender Rehan, MD, have received a $2.3 million grant from the National Institutes of Health (NIH) to research this multi-generational effect of vaping, or smoking an electronic cigarette, while pregnant.

Key Points: 
  • Investigators from The Lundquist Institute, under the leadership of Virender Rehan, MD, have received a $2.3 million grant from the National Institutes of Health (NIH) to research this multi-generational effect of vaping, or smoking an electronic cigarette, while pregnant.
  • Vaping while pregnant has become a critical topic of importance as vaping has grown significantly in popularity among young people.
  • Using established models for the study, investigators will determine whether e-cigarette vapor increases the risk of asthma in the offspring of pregnant mice.
  • Dr. Rehan has worked at The Lundquist Institute for 20 years with a research focus on lung development and repair of lung injury.

RSNA: Researchers Find Vaping Impairs Vascular Function

Retrieved on: 
Tuesday, August 20, 2019

Once inhaled, these particles can reach the alveoli of the lung, from where they are taken up by the blood vessels, thereby interfering with vascular function and promoting inflammation.

Key Points: 
  • Once inhaled, these particles can reach the alveoli of the lung, from where they are taken up by the blood vessels, thereby interfering with vascular function and promoting inflammation.
  • To study the acute effects of vaping on systemic vascular function, the researchers performed a series of MRI exams on 31 healthy non-smoking young adults (mean age 24; 14 women) before and after nicotine-free e-cigarette inhalation.
  • Dr. Caporale said further studies are needed to address the potentially adverse long-term effects of vaping on vascular health.
  • "Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Detected at Quantitative MRI."

Study Data Find Significant Differences In Exhaled Toxicants And Particles In Vapor Products Compared To Combustible Cigarettes

Retrieved on: 
Friday, June 14, 2019

Thirty adult smokers, who reported smoking a minimum of 10 combustible cigarettes per day, were recruited for this study.

Key Points: 
  • Thirty adult smokers, who reported smoking a minimum of 10 combustible cigarettes per day, were recruited for this study.
  • Data from the individual exhaled breath analysis show that levels of formaldehyde and carbon monoxide were reduced approximately 99% or more with the JUUL system compared to combustible cigarettes.
  • The use of vapor products resulted in elevated levels of propylene glycol across environments compared to cigarettes.
  • However, the average rise in airborne particles was lower with the JUUL system versus the other vapor product and combustible cigarettes.

PMI’s Latest Study Indicates E-Cigarettes Induce Less Biological Responses Associated with Cardiovascular and Pulmonary Diseases Than Cigarettes

Retrieved on: 
Thursday, March 14, 2019

The study demonstrates that after 6 months, e-cigarette vapors with and without nicotine induced a significantly lower biological responses associated with cardiovascular and pulmonary diseases than cigarette smoke.

Key Points: 
  • The study demonstrates that after 6 months, e-cigarette vapors with and without nicotine induced a significantly lower biological responses associated with cardiovascular and pulmonary diseases than cigarette smoke.
  • Tobacco harm reduction can play an important role by supplementing existing tobacco control strategies to help reduce the risk of smoking-related diseases.
  • For harm reduction to be successful, current adult smokers need access to smoke-free products that deliver nicotine but with significantly lower levels of toxicants than cigarettes.
  • Overall, the study demonstrated that e-cigarette vapor induce significantly lower biological responses associated with cardiovascular and pulmonary diseases compared with cigarette smoke.