Dendrite

EQS-News: Galimedix Therapeutics presents new scientific data showing promising neuroprotective effects of GAL-201 for the treatment of Alzheimer’s disease at AD/PD™ 2024

Retrieved on: 
Wednesday, March 13, 2024
Neurotoxicity, Learning, Myenteric plexus, Conference, Penile spines, Therapy, Memory, LTP, DSM-IV codes, Poster, Science, IND, Dendrite, Pharmaceutical industry

These new findings strongly support previous studies where GAL-201 was characterized as a promising development candidate for the treatment of AD ( Russ et.

Key Points: 
  • These new findings strongly support previous studies where GAL-201 was characterized as a promising development candidate for the treatment of AD ( Russ et.
  • The data was presented this week at the International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders ( AD/PD™ 2024: advances in science and therapy ).
  • “The positive results presented at AD/PD™ 2024 demonstrate how treatment with GAL-201 has a potential neuroprotective effect and may also improve cognitive function.
  • Furthermore, they validate that toxic Aβ oligomers and protofibrils are a major underlying cause of this devastating disease, and not the deposited forms of Aβ.

Galimedix Therapeutics presents new scientific data showing promising neuroprotective effects of GAL-201 for the treatment of Alzheimer’s disease at AD/PD™ 2024

Retrieved on: 
Friday, March 8, 2024
Neurotoxicity, Learning, Myenteric plexus, Conference, Penile spines, Therapy, Memory, LTP, DSM-IV codes, Poster, Science, IND, Dendrite, Pharmaceutical industry

These new findings strongly support previous studies where GAL-201 was characterized as a promising development candidate for the treatment of AD ( Russ et.

Key Points: 
  • These new findings strongly support previous studies where GAL-201 was characterized as a promising development candidate for the treatment of AD ( Russ et.
  • The data was presented this week at the International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders ( AD/PD™ 2024: advances in science and therapy ).
  • “The positive results presented at AD/PD™ 2024 demonstrate how treatment with GAL-201 has a potential neuroprotective effect and may also improve cognitive function.
  • Furthermore, they validate that toxic Aβ oligomers and protofibrils are a major underlying cause of this devastating disease, and not the deposited forms of Aβ.

24M Technologies Unveils Eternalyte™ — a Powerful New Electrolyte That Increases Cycle Life of Lithium-Metal Batteries

Retrieved on: 
Tuesday, February 13, 2024
Technology, Batteries, Electrode, MIT, Safety, Growth, EV, Multimedia, Lithium, Dendrite, ESS, Unit cell, Electric battery

The proprietary, liquid electrolyte formula will enable significant improvements in the cycle life and rate capability of lithium-metal batteries for electric vehicle, energy storage and consumer applications.

Key Points: 
  • The proprietary, liquid electrolyte formula will enable significant improvements in the cycle life and rate capability of lithium-metal batteries for electric vehicle, energy storage and consumer applications.
  • View the full release here: https://www.businesswire.com/news/home/20240213978873/en/
    Early test results show that Eternalyte™ enables substantial improvements in cycle life and rate capability for lithium-metal batteries.
  • (Graphic: Business Wire)
    This new innovation builds on the recent technology breakthroughs from 24M including 24M ETOP™, its electrode-to-pack battery technology, and 24M Impervio™ its new battery separator.
  • Eternalyte™ plays a key role in making that transformation happen by enabling high cycle life lithium-metal batteries,” said Naoki Ota, 24M President and CEO.

Self-extinguishing batteries could reduce the risk of deadly and costly battery fires

Retrieved on: 
Tuesday, February 6, 2024
Potassium, Sodium, Overheating, Toxicity, Needle, Electronics, Lithium, Fluorine, Research, Environment, Dendrite, Safety, Temperature, Chemistry, Climate, Noetics, Risk, Phosphorus, Electrolyte, Electric battery

By modifying affordable commercial coolants to function as battery electrolytes, we were able to produce a battery that puts out its own fire.

Key Points: 
  • By modifying affordable commercial coolants to function as battery electrolytes, we were able to produce a battery that puts out its own fire.
  • We subjected these batteries to the nail penetration test, a common method for assessing lithium-ion battery safety.
  • Driving a stainless steel nail through a charged battery simulates an internal short circuit; if the battery catches fire, it fails the test.

Why it matters

  • High outdoor temperatures or uneven temperatures within a battery pack seriously threaten batteries’ safety and durability.
  • Energy-dense batteries, such as the lithium-ion versions that are widely used in electronics and electric vehicles, contain an electrolyte formulation dominated by organic molecules that are highly flammable.
  • As scientists studying energy generation, storage and conversion, we have a strong interest in developing energy-dense and safe batteries.

How we did our work

  • However, most known nonflammable organic solvents contain fluorine and phosphorus, which are expensive and can have harmful effects on the environment.
  • We focused on a mature, safe and affordable commercial fluid called Novec 7300, which has low toxicity, is nonflammable and does not contribute to global warming.

What still isn’t known

  • For this reason, our study focused predominantly on self-extinguishing potassium-ion batteries, although it also showed that our electrolyte works well for making self-extinguishing lithium-ion batteries.
  • If the industry embraces it, we expect that companies will be able to manufacture nonflammable batteries using their existing lithium-ion battery facilities.


Apparao Rao receives funding from the R. A. Bowen Endowed Professorship funds at Clemson University. Bingan Lu does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Polymer Power: Incheon National University Researchers Enhance the Safety of Lithium Batteries

Retrieved on: 
Thursday, January 25, 2024
Lithium, PP, Silicon, Electrolyte, Assistant, Incheon National University, Research, Dendrite, Electrode, Silicon dioxide, Heat, Energy Storage Materials, Polymerization, Polymer, Explosion, Ultra, Absorption, Chemical engineering, Growth

GWANGJU, South Korea, Jan. 25, 2024 /PRNewswire/ -- Lithium-ion batteries are a widely used class of rechargeable batteries in today's world.

Key Points: 
  • GWANGJU, South Korea, Jan. 25, 2024 /PRNewswire/ -- Lithium-ion batteries are a widely used class of rechargeable batteries in today's world.
  • To avoid this, separators composed of polyolefins—a type of polymer— can be employed to maintain separation.
  • One such method is to apply ceramic coatings on the separators to improve the way they handle pressure and heat.
  • Title of original paper: Ultra-thin SiO2 nanoparticle layered separators by a surface multi-functionalization strategy for Li-metal batteries: Highly enhanced Li-dendrite resistance and thermal properties

24M® Introduces ImpervioTM — a Separator Technology That Delivers Unprecedented Safety Improvements for Lithium Batteries

Retrieved on: 
Monday, January 8, 2024
Automotive Manufacturing, EV, Electric Vehicles, Automotive, Technology, Manufacturing, Batteries, Other Manufacturing, Alternative Vehicles, Fuels, Alternative Energy, Energy, Hardware, Fire, Lithium, Dendrite, Multimedia, Fear, Chemistry, MIT, Unit cell, Stainless steel, ESS, NMC, 24M, Growth, Safety, CES

This proprietary technology enables unprecedented safety advancements for lithium-ion and lithium-metal batteries that will facilitate the prevention of catastrophic fires and massive recalls caused by metallic dendrites (i.e.

Key Points: 
  • This proprietary technology enables unprecedented safety advancements for lithium-ion and lithium-metal batteries that will facilitate the prevention of catastrophic fires and massive recalls caused by metallic dendrites (i.e.
  • 24M ImpervioTM achieves these results by obstructing metallic dendrite formation, as well as by measuring battery performance thereby enabling early fault detection.
  • The 24M ImpervioTM technology prevents this with a fail-safe approach to battery safety by:
    Dendrite prevention: Starts at the source with a proprietary separator technology that impedes the growth of dendrites.
  • 24M internal comparison tests of baseline cells, NMC/graphite cells without ImpervioTM, against identical cells with ImpervioTM, demonstrated the significant safety advantages of the ImpervioTM cell.

Beyond Cancer™ Presents Positive First-in-Human Clinical Data for Ultra-High Concentration Nitric Oxide (UNO) Therapy in Solid Tumors During the Society for Immunotherapy of Cancer (SITC) 2023 Annual Meeting

Retrieved on: 
Friday, November 3, 2023
Society for Immunotherapy of Cancer, Human, Dendritic cell, UNO, Mouse, SITC, Immunotherapy, B cell, Immune system, Annual general meeting, Dendrite, Safety, Society, Patient, Toxicity, Rare-earth element, Vaccine, Pharmaceutical industry, Cancer

GARDEN CITY, N.Y. and HAMILTON, Bermuda, Nov. 03, 2023 (GLOBE NEWSWIRE) -- Beyond Cancer, Ltd., an affiliate of Beyond Air, Inc. (NASDAQ: XAIR) that is developing ultra-high concentration nitric oxide (UNO) as an immunotherapeutic for solid tumors, today announced encouraging first-in-human and first-in-class clinical data demonstrating a promising safety profile and clear evidence of immune system activation via biomarker response. The single agent treatment in relapsed or refractory unresectable, primary or metastatic cutaneous and subcutaneous malignancies represents an unprecedented use of ultra-high concentration nitric oxide as an immunotherapeutic. These data were presented today at the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2023, which is being held in San Diego, California from November 1st to 5th via a poster presentation of abstract number 733.

Key Points: 
  • The single agent treatment in relapsed or refractory unresectable, primary or metastatic cutaneous and subcutaneous malignancies represents an unprecedented use of ultra-high concentration nitric oxide as an immunotherapeutic.
  • These data were presented today at the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2023, which is being held in San Diego, California from November 1st to 5th via a poster presentation of abstract number 733.
  • “The development of immunotherapy has pushed the frontier of cancer medicine further than ever expected,” stated Dr. Jedidiah Monson, Chief Medical Officer.
  • In addition, more than a 150% increase in T-central memory cells was observed, consistent with previously reported murine data (Sela Y et al.

Projects launch to map brain connections in mouse and macaque

Retrieved on: 
Tuesday, September 26, 2023
Electron, Neuron, Dendrite, BRAIN, Eye, Finger, Initiative, TEM, Brain, Gene expression, Cell, RNA, Bangladesh Technical Education Board, Associate, Assistant, Allen Institute, Soma, Animal, Map, Motivation, Axon, Automation, Medical imaging, Microscope, Mobile phone, Neuroanatomy

SEATTLE, Sept. 26, 2023 /PRNewswire/ -- A complete map of all the connections in an entire mammalian brain may be in sight. Allen Institute researchers have just launched three new projects to construct large, detailed maps of neuronal connections in sections of the mouse and macaque brains, with an eye toward creating full wiring diagrams of these animals' brains in the future. These projects are funded by the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative.

Key Points: 
  • SEATTLE, Sept. 26, 2023 /PRNewswire/ -- A complete map of all the connections in an entire mammalian brain may be in sight.
  • These projects are funded by the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative .
  • The goal will be to use this pipeline to image an entire hemisphere of a mouse brain at 120 nanometer resolution and the cortical basal ganglia thalamic loop (up to 10 mm3) in very fine detail to better understand how the mouse brain functions.
  • "We can actually map the whole macaque brain in a few years instead of 100 years.

Lithium-ion battery fires are a growing public safety concern − here's how to reduce the risk

Retrieved on: 
Tuesday, September 26, 2023
Electron, EV, Dendrite, Oxygen, Electricity, Fire, Temperature, Burn, Needle, Cell, Noetics, Lithium, Death, Electrode, Climate change, Risk, Water, Engineering, Electrocution, City, Growth, Transport, Internal, Safety, Injury, Software, Electric battery, Risk management

Compared with the lead-acid versions that have dominated the battery market for decades, lithium-ion batteries can charge faster and store more energy for the same amount of weight.

Key Points: 
  • Compared with the lead-acid versions that have dominated the battery market for decades, lithium-ion batteries can charge faster and store more energy for the same amount of weight.
  • These devices make our electronic gadgets and electric cars lighter and longer-lasting – but they also have disadvantages.

A new fire hazard

    • As concerns grow in cities around the world about climate change and air quality, electric vehicles have taken center stage.
    • At the same time, e-bikes and electric scooters are transforming urban transit by providing convenient, low-carbon ways to navigate crowded streets and reduce traffic congestion.
    • Fire departments in New York City and San Francisco report handling more than 660 fires involving lithium-ion batteries since 2019.
    • Clearly, there is a need for safer handling and charging practices, as well as technical improvements to batteries.

Many batteries in an EV

    • A battery holds chemicals that contain energy, with a separator between its positive and negative electrodes.
    • Depending on its design, an EV may contain dozens to thousands of single batteries, which are known as cells.
    • A standard EV will contain one large battery pack with many cells inside it.

What causes battery fires

    • Typically, a battery fire starts in a single cell inside a larger battery pack.
    • Battery short circuits may be caused by faulty external handling or unwanted chemical reactions within the battery cell.
    • Another factor that makes lithium-ion battery fires challenging to handle is oxygen generation.
    • Fires need oxygen to burn, so a battery that can create oxygen can sustain a fire.

Managing the thermal runaway problem

    • However, these mechanisms make the battery larger and heavier, which can reduce the performance of the device it powers.
    • And they may not be reliable under extreme temperatures or pressures, such as those produced in a car crash.
    • Making a thermal runaway in a battery pack less intense requires a mix of software and hardware improvements.
    • Park the vehicle away from extremely hot or cold surroundings – for example, park in shade during heat waves – to prevent thermal stress on the battery.

Zeta Energy Begins Extreme Temperature Testing of its Lithium-Sulfur Batteries for ARPA-E Project

Retrieved on: 
Tuesday, August 1, 2023
Zeta, Dendrite, Carbon, 3D, Temperature, Cell, Electric vehicle, Government, ARPA, EVS, Electrode, Lithium, Electric battery

HOUSTON, Aug. 1, 2023 /PRNewswire/ -- Zeta Energy announced today that it has begun building very high density electrodes and is conducting extreme temperature testing of cells as part of its ARPA-E EVs4ALL project.

Key Points: 
  • HOUSTON, Aug. 1, 2023 /PRNewswire/ -- Zeta Energy announced today that it has begun building very high density electrodes and is conducting extreme temperature testing of cells as part of its ARPA-E EVs4ALL project.
  • Our electrodes have already achieved a density that exceeds the targets we had planned for the project.
  • We are now engaged in extreme temperature testing of cells built from our electrodes, and so far, we have shown that the batteries work at -20°C.
  • Zeta Energy pairs this anode with a proprietary sulfurized-carbon cathode that suppresses the formation of soluble polysulfides, resulting in sulfur-based batteries that offer unprecedented stability, performance, and low cost.