IMM

UpMetrics Launches Free Impact Framework Building Tool for Impact Organizations

Retrieved on: 
Tuesday, March 26, 2024
Decal, Organization, Learning, Part, SAN, Table, Overalls, Data collection, Nonprofit organization, IMM, Video game

SAN FRANCISCO, March 26, 2024 /PRNewswire-PRWeb/ -- UpMetrics, an impact measurement and management software company, today announced the release of its new and improved Impact Measurement and Management (IMM) Suite, purpose-built to help mission-driven organizations measure, maximize, and showcase the positive social or environmental impact of their work.

Key Points: 
  • As part of this platform rollout, UpMetrics provides free access to the Impact Framework Builder functionality as part of a Starter package offering.
  • "Our Impact Framework Builder is a free, easy-to-use tool that empowers organizations to measure, manage and communicate their impact, paving the way to access mission aligned capital that will maximize outcomes and long-term sustainability."
  • In alignment with their vision towards creating a data-driven ecosystem that drives capital and resources to impact, UpMetrics will be delivering additional updates to its platform throughout 2024, including impact framework publishing tools to connect impact organizations and an advanced two-sided portfolio reporting feature to streamline data collection and information sharing between funders and impact producers.
  • For more information, visit https://upmetrics.com/platform , or register for the free Impact Framework Builder via https://upmetrics.com/getstarted

Thebes Trust Alternate Thought Opens a Path for Directions Toward Building Harmony Among Adversaries

Retrieved on: 
Friday, March 22, 2024
Universal mind, Communication, Universal law, Ministry (collective executive), Religion, Internet, Vow, Public theology, Society, University, LAS, Sociology, Trust, Spirit, Catalog, Ministry, Family, Probability, Orient, Ordination, IMM

Thus, we will address subjects using Universal Law, applying the cause factors to determine where another path might have been followed. The Trust will work with other graduate metaphysical teachers in association with the International Metaphysical Ministry -- (IMM) - (https://www.internationalmetaphysicalministry.com). Each graduate of the University of Metaphysics is opportunely ordained as a Metaphysical Minister at commencement as they work in their chosen field.

Key Points: 
  • Thebes addresses those subjects by applying universal law, religious precepts, and Sociological norms—Thebes Trust partners with other ordained Metaphysical Ministers.
  • Thebes Trust adheres to the wording of the Ordination and the Vows accepted by William Cadmus.
  • LAS VEGAS, March 22, 2024 /PRNewswire-PRWeb/ -- Thebes Media ( https://www.thebesmedia.com ) officially announces the dawning of its product development for its Ministry.
  • Thus, we will address subjects using Universal Law, applying the cause factors to determine where another path might have been followed.

Immutep Announces First Clinical Data from 90mg Dosing of Efti

Retrieved on: 
Tuesday, March 5, 2024
MBC, Autoimmune disease, Safety, ASX, Observation, Paclitaxel, Patient, Disease, IMM, Cancer, Pharmaceutical industry

Updated safety data from patients with HR-positive/HER2-negative/low metastatic breast cancer (MBC) treated with this innovative immuno-oncology (IO)-chemotherapy combination reveal no treatment-emergent serious adverse events.

Key Points: 
  • Updated safety data from patients with HR-positive/HER2-negative/low metastatic breast cancer (MBC) treated with this innovative immuno-oncology (IO)-chemotherapy combination reveal no treatment-emergent serious adverse events.
  • Additionally, all treatment-emergent adverse events during the safety observation period to date have been of mild severity.
  • The biologically active 30mg efti dose, previously the highest dose of efti ever tested, has demonstrated a stronger immune response and greater efficacy than lower dosing levels (1mg, 6mg) in multiple clinical trials.
  • The ongoing randomized Phase II portion of the trial, which will include up to 58 evaluable patients, is focused on whether 90mg efti dosing is safe and more efficacious than 30mg dosing.

Immutep Quarterly Activities Report Q2 FY24

Retrieved on: 
Tuesday, January 30, 2024
Well, OS, CPS, Survival, PD-L1, Congress, NSCLC, IMM, Lung cancer, Patient, TPS, Safety, Immutep, Pembrolizumab, Cancer, ASX, Autoimmune disease, Pharmaceutical industry

SYDNEY, AUSTRALIA, Jan. 30, 2024 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep” or “the Company”), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune disease, provides an update on the ongoing development of its product candidates, eftilagimod alpha (efti) and IMP761 for the quarter ended 31 December 2023 (Q2 FY24).

Key Points: 
  • Cash receipts from customers in Q2 FY24 were $38k, compared to $132k in Q1 FY24.
  • The net cash used in G&A activities in the quarter was $0.8 million, compared to $1.6 million in Q1 FY24.
  • The net cash used in R&D activities in the quarter was $6.9 million, compared to $9.7 million in Q1 FY24.
  • Total net cash outflows used in operating activities in the quarter were $5.5 million compared to $12.9 million in Q1 FY24.

First Patient Dosed in Trial Evaluating Efti and the Anti-PD-L1 Therapy BAVENCIO® in Metastatic Urothelial Cancer

Retrieved on: 
Thursday, January 4, 2024
IO, Merck Group, ASX, Autoimmune disease, Immune system, Death, Bladder cancer, Carcinoma, Hope, IMM, PD-L1, Avelumab, Research, Cancer, Transitional cell carcinoma, Patient, Safety, Transitional epithelium

SYDNEY, AUSTRALIA, Jan. 04, 2024 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep” or “the Company”), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune disease, today announces that the first patient has been enrolled and safely dosed in the INSIGHT-005 Phase I trial. The investigator-initiated study jointly funded with Merck KGaA, Darmstadt, Germany, will evaluate eftilagimod alpha (“efti”) in combination with BAVENCIO® (avelumab) in up to 30 patients with metastatic urothelial carcinoma.

Key Points: 
  • The investigator-initiated study jointly funded with Merck KGaA, Darmstadt, Germany, will evaluate eftilagimod alpha (“efti”) in combination with BAVENCIO® (avelumab) in up to 30 patients with metastatic urothelial carcinoma.
  • Encouragingly, responses were achieved even in cancer patients with low and negative PD-L1 expression, who typically would not be expected to respond to anti-PD-(L)1 therapy.
  • Daniel Pink, as part of the investigator-initiated INSIGHT platform for studies investigating efti in different combination treatments and routes of administration.
  • For 2023, it was estimated there would be 82,290 new cases of bladder cancer and 16,710 deaths in the US alone.1

Immutep Receives Constructive Regulatory Feedback on TACTI-004 Registrational Trial in Metastatic Non-Small Cell Lung Cancer

Retrieved on: 
Thursday, December 21, 2023
Lung cancer, ASX, Autoimmune disease, Food, PEI, FDA, Paul Ehrlich Institute, IMM, Cancer, Committee, Safety, NSCLC, PD-L1, CHMP, Pharmaceutical industry

SYDNEY, AUSTRALIA, Dec. 21, 2023 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep” or “the Company”), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune disease, today announces constructive feedback has been received from the Paul-Ehrlich-Institut (“PEI”), a German regulatory authority and part of the Committee for Medicinal Products for Human Use (CHMP), regarding the planned TACTI-004 Phase III trial of eftilagimod alpha (“efti”) for first line treatment of metastatic non-small cell lung cancer (NSCLC).

Key Points: 
  • The PEI is supportive of Immutep moving into a registrational trial in first line NSCLC and evaluating efti in combination with an anti-PD-1 therapy in a chemotherapy-free regimen or as a triple combination approach that includes chemotherapy.
  • Also, the PEI acknowledged the good safety profile of efti in combination with anti-PD-1 therapy.
  • Immutep plans to announce its final trial design for TACTI-004 in Q1 of CY2024.
  • Immutep CEO, Marc Voigt, commented: “We appreciate the valuable feedback from the PEI and look forward to additional discussions with other regulatory agencies in the coming months.

Immutep Receives A$2.6 million R&D Tax Incentive from French Government

Retrieved on: 
Thursday, December 7, 2023
Immunotherapy, Recherche, ASX, Research, European, IMM, Cancer, Calendar, CIR, Immutep, Eftilagimod alpha

SYDNEY, AUSTRALIA, Dec. 07, 2023 (GLOBE NEWSWIRE) --  Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep“ or “the Company”), a biotechnology company developing novel LAG-3 related immunotherapy treatments for cancer and autoimmune diseases, is pleased to announce it has received a €1,595,475 (~ A$2,628,354 ) research and development (R&D) tax incentive payment in cash from the French Government under its Crédit d’Impôt Recherche scheme (CIR).

Key Points: 
  • The “Crédit d’Impôt Recherche” (CIR), meaning “Research Tax Credit”, is a French government tax incentive by which French companies conducting research and development activities in Europe can be reimbursed 30% of their eligible expenditure.
  • Immutep qualifies for the CIR tax incentive through its subsidiary Immutep S.A.S.
  • Immutep also qualifies for cash rebates from the Australian Federal Government’s R&D tax incentive program in respect of expenditure incurred on eligible R&D activities conducted in Australia.
  • As previously announced, in October 2023, the company received an A$1.13 million cash rebate from the Australian Federal Government’s R&D tax incentive program for the eligible R&D activities conducted in financial year 2022.

Immutep Announces Site Expansion for INSIGHT-003 Phase I Trial

Retrieved on: 
Wednesday, November 22, 2023
Lung cancer, ASX, ESMO, Autoimmune disease, IMM, Cancer, TPS, Patient, NSCLC, Pembrolizumab, Pharmaceutical industry

This site expansion will support faster enrolment in this cost-efficient, investigator-initiated study evaluating eftilagimod alpha (efti) in combination with the anti-PD-1 therapy KEYTRUDA® (pembrolizumab) and doublet chemotherapy for first line treatment of non-squamous non-small cell lung cancer (NSCLC).

Key Points: 
  • This site expansion will support faster enrolment in this cost-efficient, investigator-initiated study evaluating eftilagimod alpha (efti) in combination with the anti-PD-1 therapy KEYTRUDA® (pembrolizumab) and doublet chemotherapy for first line treatment of non-squamous non-small cell lung cancer (NSCLC).
  • The strength of the early clinical data in this first-in-man triple combination study led to its increase to 50 patients.
  • The extension opened in mid-2023 and 29 patients have been enrolled to date.
  • With the addition of the new sites, the trial is expected to complete recruitment in 1H CY2024.

Ilant Health Wins for Innovative Approach to Obesity Management

Retrieved on: 
Thursday, December 14, 2023
General Health, Professional Services, Health, Human Resources, Health equity, Medicaid, Organization, Cleveland Clinic, Obesity, McKinsey & Company, Home, Population health, IMM, Molina Healthcare, HPIR, Nursing, Anthem, Medicare

Ilant Health, which provides a value-based approach to obesity treatment, is the first company to win all 3 Innovation Roundtable Academies – Employer (EHIR), Health Plan (HPIR), and Provider (PHIR).

Key Points: 
  • Ilant Health, which provides a value-based approach to obesity treatment, is the first company to win all 3 Innovation Roundtable Academies – Employer (EHIR), Health Plan (HPIR), and Provider (PHIR).
  • These groups represent over 100 innovative companies, 14 innovative health plans, and 11 leading provider systems and judging was conducted by individuals from innovative member companies such as State Farm, Premera, and Cleveland Clinic.
  • Companies are assessed for fit with market needs, innovative approach, operational fundamentals, and potential industry impact.
  • This allows Ilant to support different employer types, Medicare, and Medicaid plans, making it one of the few organizations addressing obesity health equity needs.

MARKET MONITOR FINDS PJM WHOLESALE ELECTRICITY MARKETS COMPETITIVE

Retrieved on: 
Thursday, November 9, 2023
Sportradar, Behavior, Wind, Policy, PJM Interconnection, FTR, PJM, Load, MMU, ARR, LMP, Electricity, IMM, CP, Kilowatt-hour, Overalls, Rare-earth element, Renewable energy

EAGLEVILLE, Pa., Nov. 9, 2023 /PRNewswire/ -- PJM Interconnection's wholesale electric energy market produced competitive results during the first nine months of 2023, according to the 2023 Quarterly State of the Market Report for PJM: January through September released today by Monitoring Analytics, LLC, the Independent Market Monitor for PJM.

Key Points: 
  • 2023 Quarterly State of the Market Report for PJM: January through September
    EAGLEVILLE, Pa., Nov. 9, 2023 /PRNewswire/ -- PJM Interconnection's wholesale electric energy market produced competitive results during the first nine months of 2023, according to the 2023 Quarterly State of the Market Report for PJM: January through September released today by Monitoring Analytics, LLC, the Independent Market Monitor for PJM.
  • The report is the Independent Market Monitor's assessment of the competitiveness of the wholesale electricity markets managed by PJM in 13 states and the District of Columbia.
  • The report includes analysis of market structure, participant behavior and market performance for each of the PJM markets.
  • The Independent Market Monitor (also known as the Market Monitoring Unit or MMU or IMM) evaluates the operation of PJM's wholesale markets to identify ineffective market rules and tariff provisions, proposes improvements to market rules and tariff provisions when needed, monitors compliance with and implementation of the market rules, identifies potential anticompetitive behavior by market participants and provides comprehensive market analysis critical for informed policy and decision making.