Berns

Breakthrough Study Supports Genetic Editing as a Potential Treatment for Rare Rapid-Aging Disease Progeria

Retrieved on: 
Wednesday, January 6, 2021

Without the FDA-approved treatment Zokinvy (lonafarnib), children with Progeria die of heart disease at an average age of 14.5 years, due to premature atherosclerosis resulting in heart attacks.

Key Points: 
  • Without the FDA-approved treatment Zokinvy (lonafarnib), children with Progeria die of heart disease at an average age of 14.5 years, due to premature atherosclerosis resulting in heart attacks.
  • Zokinvy increases average lifespan by 2.5 years and improves some symptoms of Progeria, but it does not address the genetic mutation that causes the disease.
  • Using a newer form of genetic editing, known as base editing, researchers found that they could reverse the mutation that causes Progeria, improving disease symptoms and dramatically increasing lifespan in a Progeria mouse model.
  • The Progeria Research Foundation (PRF) is a nonprofit organization established in 1999 by the family of Sam Berns, a child with Progeria.

Proceeds from Priority Review Voucher Sale Will Fund Search for Cure for the Rapid Aging Disease Progeria

Retrieved on: 
Monday, November 23, 2020

PEABODY,Mass., Nov. 23, 2020 /PRNewswire/ --The Progeria Research Foundation (PRF) today announced that it will receive half of the net proceeds of the sale of a Priority Review Voucher (PRV).

Key Points: 
  • PEABODY,Mass., Nov. 23, 2020 /PRNewswire/ --The Progeria Research Foundation (PRF) today announced that it will receive half of the net proceeds of the sale of a Priority Review Voucher (PRV).
  • Zokinvy is a farnesyltransferase inhibitor (FTI) that has shown survival benefit in children with Progeria.
  • The Progeria Research Foundation (PRF) was established in 1999 by the family of Sam Berns, a child with Progeria.
  • PRF is the only non-profit organization solely dedicated to finding treatments and the cure for Progeria and its aging-related conditions, including heart disease.

DigiPlex Hands Sustainable Project of the Year Award to Renova Group at CIO Awards 2018

Retrieved on: 
Tuesday, December 18, 2018

DigiPlex , the leading data centre company in the Nordic region, handed the award for Sustainable Project of the Year to Renova Group , for its customer portal solution.

Key Points: 
  • DigiPlex , the leading data centre company in the Nordic region, handed the award for Sustainable Project of the Year to Renova Group , for its customer portal solution.
  • The awards ceremony took place at CIO Awards 2018 at Berns Salonger in Stockholm yesterday.
  • Like Renova Group, DigiPlex is constantly looking for new innovative ways to become even more sustainable.
  • The six finalists for the award Sustainable Project 2018 were: