Saipan

BioAegis Therapeutics to Sponsor a Webinar, Below the Eyes of the Hippopotamus: The Expanding Spectrum of Auto- and Hyper- Inflammatory Diseases

Retrieved on: 
Wednesday, May 10, 2023
Storm, Life, Atlas, Pathology, Phagocytosis, Massachusetts General Hospital, MBA, Harvard Medical School, Autoimmunity, Harvard University, Georgetown University, Eye, Wharton School of the University of Pennsylvania, Patient, Castleman Disease Collaborative Network, The New York Times, Faculty, Merck, Laboratory, Infection, BS, University, Research, EPA, Hematology, Hospital, Bacteria, FDA, Vaccine, NIH, Tufts University, Yale School of Medicine, Cancer, NLRP3, Biomarker, Hospital of the University of Pennsylvania, Public health, Publication, Saipan, Master of Science, Merck & Co., Therapy, Inflammation, Q&A, Autoinflammatory diseases, Penn, Internal medicine, Infectious Diseases Society of America, Immunosuppression, Gene, Flexner Report, GMA, Pharmaceutical industry, Nursing, MD, Brigham, FIDSA

The webinar, Below the Eyes of the Hippopotamus: The Expanding Spectrum of Auto- and Hyper- Inflammatory Diseases will delve beneath the surface of this rapidly growing field of auto-inflammatory and hyper-inflammatory diseases.

Key Points: 
  • The webinar, Below the Eyes of the Hippopotamus: The Expanding Spectrum of Auto- and Hyper- Inflammatory Diseases will delve beneath the surface of this rapidly growing field of auto-inflammatory and hyper-inflammatory diseases.
  • The major scientific breakthrough in identifying genes responsible for autoinflammatory diseases and related genotypes.
  • Key biomarkers for autoinflammatory diseases and new targets for treatments, like the NLRP3 inflammasome.
  • A live Q&A discussion with key opinion leader, David Fajgenbaum, MD, will follow the presentation.

BioAegis Therapeutics Announces Two Studies Exploring the Role of ‘Inflammation Regulator’ Gelsolin in Type 2 Diabetes

Retrieved on: 
Thursday, April 13, 2023
Gelsolin, Infection, NORTH, Hyperglycemia, Type 2 diabetes, University, Diabetes, Neutrophil, NLRP3, Woman, Intramural sports, Journal of Translational Medicine, Inflammation, Bangladesh Technical Education Board, Maryland School, University of Maryland School of Medicine, Ageing, US, MP, Oxidative stress, Type, Saipan, Journal, Translational medicine, Patient, Mouse, Therapy, White, Foundation for the National Institutes of Health, NIH Intramural Research Program, Pharmaceutical industry, Dietary supplement, Vaccine, Poverty

NORTH BRUNSWICK, N.J., April 13, 2023 (GLOBE NEWSWIRE) -- BioAegis Therapeutics, Inc., a clinical-stage company developing therapies for inflammatory diseases through a portfolio built around plasma gelsolin (pGSN), a highly conserved and abundant endogenous human immune regulatory protein, announces publication of two new research studies exploring gelsolin’s role in type 2 diabetes, an inflammation-related metabolic disease.

Key Points: 
  • Low levels of gelsolin identified in individuals with type 2 diabetes living below poverty.
  • It explored the role of microparticles (MPs) which drive inflammation in individuals with diabetes.
  • Type 2 diabetic subjects with foot ulcers were shown to have up to 14-fold elevations of blood-borne F-actin-coated microparticles.
  • White adults with diabetes had lower levels compared to White adults without diabetes and to African American individuals either with or without diabetes.

BioAegis Therapeutics Announces FDA Clearance of IND for its ‘Inflammation Regulator Protein,’ Gelsolin, for the Treatment of ARDS

Retrieved on: 
Thursday, January 26, 2023
Administration, Infection, Food, Inflammation, IND, ASPR, Acute respiratory distress syndrome, Drive, Gelsolin (cellular), Respiratory distress syndrome, BARDA, Lung, Patient, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, FDA, ICU, Saipan, Mortality, Death, Plasma, Therapy, Pharmaceutical industry, Management, Vaccine

ARDS is a serious inflammatory condition for which there are severe consequences with no current therapies other than supportive care.

Key Points: 
  • ARDS is a serious inflammatory condition for which there are severe consequences with no current therapies other than supportive care.
  • Its genesis can be from various etiologies, with severe infection being a frequent cause.
  • BioAegis is collaborating with the BARDA DRIVe Solving Sepsis program, to further develop plasma gelsolin for ARDS.
  • Plasma gelsolin is critically depleted in ARDS patients and has been shown to address both injurious and infectious inflammation in multiple studies.

BioAegis Therapeutics Highlights Recent Article on its Novel Host-Directed Protein, Plasma Gelsolin, for Inflammatory Diseases

Retrieved on: 
Monday, December 5, 2022
HDT, Kidney, Drive, Saipan, Inflammation, Telephone numbers in South Africa, Sepsis, Infection, Disease, Multiple sclerosis, IP, Plasma, BARDA, Therapy, Blood, Pharmaceutical industry

Companies are challenged with finding treatments for the countless autoimmune and inflammatory disorders that affect millions of people globally.

Key Points: 
  • Companies are challenged with finding treatments for the countless autoimmune and inflammatory disorders that affect millions of people globally.
  • The ravages of inflammatory disease are on the rise and drive considerable morbidity as well as stress on the healthcare system.
  • It holds over 40 patents issued for coverage of infection, inflammatory disease, renal failure, multiple sclerosis, and other neurologic diseases.
  • BioAegis will also have US biologics exclusivity and has recently filed new IP in areas of unmet need.

Researchers Discover Previously Unknown Role of BioAegis’ Therapeutic Gelsolin as Key Signaling Protein Vital for Regulating Immune Cell Inflammatory Response

Retrieved on: 
Tuesday, September 28, 2021
Therapy, Recombinant, Degenerative disease, Steroid, Infection, Inflammation, Immunity, Patient, Population, Bacteria, IP, Journal, Injury, End organ damage, Kidney, Quorum sensing, CEO, Death, Phenotype, Disease, Risk, Programmed cell death protein 1, Saipan, Science, COVID-19, Pneumonia, Lists of diseases, Telephone numbers in South Africa, Cell, California Uninsured Patient Hospital Pricing Litigation, NORTH, Multiple sclerosis, GLOBE, Pharmaceutical industry, Vaccine

NORTH BRUNSWICK, New Jersey, Sept. 28, 2021 (GLOBE NEWSWIRE) -- BioAegis Therapeutics Inc., a clinical stage, private company developing therapies for infectious, inflammatory, and degenerative diseases based on a portfolio built around gelsolin technology, announced that a previously unknown role of gelsolin in a signaling system in macrophages was published in the Journal of Immunology.

Key Points: 
  • The paper, Quorum Sensing by Gelsolin Regulates Programmed Cell Death 4 Expression and a Density-Dependent Phenotype in Macrophages , was recently published in the Journal of Immunology.
  • The study shows that plasma gelsolin (pGSN) controls this process by regulating the expression of a protein known as Programmed Cell Death 4 (PCD4).
  • Gelsolin, a naturally occurring human protein that is abundant in healthy individuals, is a key component of the bodys innate immune system.
  • BioAegis will also have US biologics exclusivity and has recently filed new IP in areas of unmet need.

First Hawaiian Bank Goes Live with MX Helios for Mobile Banking, Empowering Customers with Financial Insights

Retrieved on: 
Thursday, May 27, 2021
BNP Paribas, Countries, First Hawaiian Bank, Islands of the Pacific Ocean, Islands, Hawaii, Saipan, Guam

First Hawaiian Bank has a legacy of serving generations of families, individuals and businesses.

Key Points: 
  • First Hawaiian Bank has a legacy of serving generations of families, individuals and businesses.
  • Powered by MX's industry-leading data platform, First Hawaiian Bank will continue to support its customers throughout Hawaii, Guam, Saipan and the U.S. by delivering a single, secure location to interact with all of its financial relationships.
  • "MX has been a great partner for us in developing a mobile platform that gives our customers a holistic view of their finances with unique insights that help them make sound financial decisions."
  • Its principal subsidiary, First Hawaiian Bank, was founded in 1858 and is Hawaii's largest financial institution with branch locations throughout Hawaii, Guam and Saipan.

Granite Awarded $16 Million Task Order Contract by the Federal Emergency Management Agency

Retrieved on: 
Monday, October 12, 2020
Commercial Building & Real Estate, Construction & Property, Other Defense, Contracts, Urban planning, Architecture, Other Construction & Property, Defense, Residential Building & Real Estate, Countries, Landforms, Geography of Micronesia, Insular areas of the United States, Small Island Developing States, Islands, Federal Emergency Management Agency, Saipan, Office of Emergency Management, Granite, GVA

Granite (NYSE:GVA) announced it has been awarded a $16 million task order contract by the U.S. Department of Homeland Securitys Federal Emergency Management Agency (FEMA) for the Permanent Housing Construction - New Construction for Disaster Declaration project in Saipan, CNMI.

Key Points: 
  • Granite (NYSE:GVA) announced it has been awarded a $16 million task order contract by the U.S. Department of Homeland Securitys Federal Emergency Management Agency (FEMA) for the Permanent Housing Construction - New Construction for Disaster Declaration project in Saipan, CNMI.
  • The contract will be booked into Granite's fourth quarter 2020 backlog.
  • As part of their design-build services, Granite will be responsible for all permitting, site design and construction of all the cast-in-place concrete homes.
  • Our team in Guam is well-positioned to perform this work and leverage our locally-established infrastructure, said Granite Senior Vice President and Group Manager Matt Tyler.

Hawthorne Cat Announces New Parts & Service Special Offers

Retrieved on: 
Tuesday, May 26, 2020
Insular areas of the United States, Small Island Developing States, Kingdom of Reman, Countries, Guam, Saipan, Caterpillar Inc., American Samoa, Landforms, Islands

Our new limited-time offers include special savings on Cat Reman Turbos, Precious Metals Kits, and Performance Pro Parts Only Plans.

Key Points: 
  • Our new limited-time offers include special savings on Cat Reman Turbos, Precious Metals Kits, and Performance Pro Parts Only Plans.
  • "Hawthorne Cat makes it easy to get the most reliable Cat parts and services," says Chandra Ramamoorthy, Director of Product Support Operations.
  • "Our new Parts and Service Specials include limited-time offers on all of the parts and services you need to keep your fleet running on time and on budget."
  • Hawthorne Cat is the authorized dealer for Cat construction and power equipment in San Diego, Hawaii, Guam, Saipan, and American Samoa.

World Premiere of Restored 1950's Autonomous Concept Vehicle Golden Sahara II with Goodyear Tires

Retrieved on: 
Tuesday, March 5, 2019
Goodyear Tire and Rubber Company, Automotive industry, Goodyear, Custom car, Motor vehicles, Companies

GENEVA, March 5, 2019 /PRNewswire/ -- In collaboration with Klairmont Kollections, Goodyear unveiled the restored Golden Sahara II at the 2019 Geneva International Motor Show.

Key Points: 
  • GENEVA, March 5, 2019 /PRNewswire/ -- In collaboration with Klairmont Kollections, Goodyear unveiled the restored Golden Sahara II at the 2019 Geneva International Motor Show.
  • An iconic custom car of the 1950s and 60s, the Golden Sahara II was one of the first concepts of autonomous vehicles and was fitted with glowing, see-through tires that were custom developed by Goodyear.
  • "Goodyear's collaboration on the Golden Sahara II project was our first step in shaping the future of autonomous mobility."
  • The Golden Sahara II was restored with the help of Speakeasy Customs and Classics in Chicago and was presented at Geneva on four, newly-built Goodyear translucent tires.

Huawei and Gelsenkirchen Sign MoU for Smart City Cooperation at MWC2019

Retrieved on: 
Friday, March 1, 2019
Telecommunications, Huawei, Internet of things, Smart city, Gelsenkirchen

BARCELONA, Spain, Feb. 28, 2019 /PRNewswire/ -- Huawei and Gelsenkirchen signed a Memorandum of Understanding for Smart City Cooperation during the Mobile World Congress (MWC2019) held in Barcelona, Spain.

Key Points: 
  • BARCELONA, Spain, Feb. 28, 2019 /PRNewswire/ -- Huawei and Gelsenkirchen signed a Memorandum of Understanding for Smart City Cooperation during the Mobile World Congress (MWC2019) held in Barcelona, Spain.
  • The City of Gelsenkirchen and Huawei Technologies have agreed to partner on the development of a Smart City platform to deliver government services to citizens, tourists and businesses in this German city.
  • The first step has been the creation of an OpenAir Innovation Lab that functions as:
    A Smart City showcase for citizens, businesses and tourists
    The objectives are to implement and test public, highly-visible Smart City services as well as prove the recommended approach to building a common, standardized platform for Smart City service delivery.
  • Huawei will continue to be a strategic technology partner for the City of Gelsenkirchen, delivering the communications and computing infrastructure that has allowed Gelsenkirchen to distinguish itself as the "Connected City".