Secondary metabolites

Trevena Announces Publication of OLINVYK® Health Economic Model in Journal of Comparative Effectiveness Research

Retrieved on: 
Monday, July 12, 2021
Drugs, Opioids, Psychoactive drugs, Morphinans, Euphoriants, Pharmacy, Opiates, Secondary metabolites, Oliceridine, Morphine, Heroin, Medication

CHESTERBROOK, Pa., July 12, 2021 (GLOBE NEWSWIRE) -- Trevena, Inc. (Nasdaq: TRVN), a biopharmaceutical company focused on the development and commercialization of novel medicines for patients with central nervous system (CNS) disorders, today announced the publication of the health economic model for OLINVYK (oliceridine) injection in Journal of Comparative Effectiveness Research.

Key Points: 
  • CHESTERBROOK, Pa., July 12, 2021 (GLOBE NEWSWIRE) -- Trevena, Inc. (Nasdaq: TRVN), a biopharmaceutical company focused on the development and commercialization of novel medicines for patients with central nervous system (CNS) disorders, today announced the publication of the health economic model for OLINVYK (oliceridine) injection in Journal of Comparative Effectiveness Research.
  • The model estimates the budget impact of OLINVYK compared to IV morphine when used on-demand in a hospital setting for postoperative pain.
  • I am pleased to have the health economic model now in the published literature a significant milestone that will continue to support the formulary review process for OLINVYK, said Mark A. Demitrack, M.D., Senior Vice President and Chief Medical Officer of Trevena.
  • As previously announced, the model calculates a significant decrease in total cost of care per 1,000 patients associated with OLINVYK, compared to IV morphine.

Codeine (CAS 76-57-3) Global Market Research Report 2021 - ResearchAndMarkets.com

Retrieved on: 
Friday, June 18, 2021
Health, General Health, Drugs, Morphinans, Branches of biology, Opiates, Secondary metabolites, Antidiarrhoeals, Codeine, Prodrugs

The "Codeine (CAS 76-57-3) Global Market Research Report 2021" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Codeine (CAS 76-57-3) Global Market Research Report 2021" report has been added to ResearchAndMarkets.com's offering.
  • This global report is a result of industry experts' diligent work on researching the world market of Codeine.
  • The fifth chapter deals with Codeine market trends and forecast, distinguish Codeine manufacturers and suppliers.
  • The Codeine global market report key points:

TBD Media Group's New Campaign Gives a Platform to the Leaders at this Pivotal Moment of Business and Society

Retrieved on: 
Thursday, June 17, 2021
Aviation, Aviators, Branches of biology, Fellows of the Royal Society, Penicillins, Penicillium, Microbiology, Secondary metabolites, Alexander Fleming, Antibiotic, Fleming, Wright brothers

LONDON, June 17, 2021 /PRNewswire/ --TBD Media Group announces the launch of a brand-new and ground-shaking new documentary series: 50 Global Leaders.

Key Points: 
  • LONDON, June 17, 2021 /PRNewswire/ --TBD Media Group announces the launch of a brand-new and ground-shaking new documentary series: 50 Global Leaders.
  • Throughout history there have been pivotal moments that changed society, unlocked new potential, and altered the world as we knew it thereafter.
  • In 1903, the Wright Brothers achieved the first airplane flight, claiming the skies for personal and commercial travel.
  • In 1928, Doctor Alexander Fleming discovered Penicillin, paving the way for research into antibiotics and revolutionising how we use medicine.

TBD Media Group's New Campaign Gives a Platform to the Leaders at this Pivotal Moment of Business and Society

Retrieved on: 
Thursday, June 17, 2021
Aviation, Aviators, Branches of biology, Fellows of the Royal Society, Penicillins, Penicillium, Microbiology, Secondary metabolites, Alexander Fleming, Antibiotic, Fleming, Wright brothers

LONDON, June 17, 2021 /PRNewswire/ --TBD Media Group announces the launch of a brand-new and ground-shaking new documentary series: 50 Global Leaders.

Key Points: 
  • LONDON, June 17, 2021 /PRNewswire/ --TBD Media Group announces the launch of a brand-new and ground-shaking new documentary series: 50 Global Leaders.
  • Throughout history there have been pivotal moments that changed society, unlocked new potential, and altered the world as we knew it thereafter.
  • In 1903, the Wright Brothers achieved the first airplane flight, claiming the skies for personal and commercial travel.
  • In 1928, Doctor Alexander Fleming discovered Penicillin, paving the way for research into antibiotics and revolutionising how we use medicine.

ALK Acquires OTIPRIO® (ciprofloxacin otic suspension), Broadening Treatment Solutions for Healthcare Providers and Patients

Retrieved on: 
Thursday, June 3, 2021
Drugs, Health, Fluoroquinolone antibiotics, Otologicals, Microbiology, Scottish inventions, Secondary metabolites, Otitis media, Ciprofloxacin, Otitis, Ofloxacin, Penicillin

Additionally, ALK will also now offer our other allergy immunotherapy products and penicillin allergy testing to an expanded set of healthcare provider specialties."

Key Points: 
  • Additionally, ALK will also now offer our other allergy immunotherapy products and penicillin allergy testing to an expanded set of healthcare provider specialties."
  • OTIPRIO is a sterile, preservative-free, otic suspension of 6 percent ciprofloxacin administered as a single-dose by a healthcare professional.
  • For AOE, OTIPRIO is administered as a single 0.2 mL (12 mg) administration to the external ear canal of each affected ear.
  • The tubes are placed for the treatment of persistent or recurrent otitis media (infection and/or inflammation of the middle ear).

ZetrOZ Systems Partners With the National Institute on Aging

Retrieved on: 
Thursday, April 15, 2021
Drugs, Opioids, Medical specialties, Hepatotoxins, Morphinans, Nonsteroidal anti-inflammatory drugs, Opiates, Secondary metabolites, Codeine, Ibuprofen, Aspirin, Morphine

Pain can be managed by either NSAIDs like aspirin and ibuprofen to powerful narcotics like morphine and codeine.

Key Points: 
  • Pain can be managed by either NSAIDs like aspirin and ibuprofen to powerful narcotics like morphine and codeine.
  • While effective, oral or intravenous administration of these drugs in geriatric patients puts them at higher risk of complications due to possible comorbidities or side effects.
  • The organization also has manufacturing facilities across the United States.
  • ZetrOZ Systems produced UltrOZ, sam Sport and samPro 2.0 to provide safe and effective treatment options for prevalent conditions such as arthritis.

Transplant Patients with a Penicillin Allergy Label Experience a Higher Rate of Adverse Effects When Using Non-Penicillin Antibiotics

Retrieved on: 
Tuesday, February 16, 2021
Branches of biology, Penicillins, Microbiology, Scottish inventions, Secondary metabolites, Drugs, Health care, Penicillium, Side effects of penicillin, Antibiotic, Drug resistance, Antibiotic use in dentistry

Since individuals with a penicillin allergy label are given alternative antibiotic regimens, the researchers aimed to investigate if transplant patients with a penicillin allergy label would have worse outcomes from receiving alternative regimens.

Key Points: 
  • Since individuals with a penicillin allergy label are given alternative antibiotic regimens, the researchers aimed to investigate if transplant patients with a penicillin allergy label would have worse outcomes from receiving alternative regimens.
  • A retrospective analysis was done to compare outcomes between these patients to transplant patients treated for the same infections who did not have a penicillin allergy label.
  • Compared to the control group, transplant patients with the penicillin allergy label had a higher rate of adverse effects from non-penicillin antibiotics (8.9% compared to 6.3%).
  • The transplant patients with a penicillin allergy label also had a lower rate of infection with multi-drug resistant organisms (0.3% compared to 1%).

Trevena, Inc. Provides Update on Commercial Launch Activities for OLINVYK™ and Announces Anticipated Pipeline Catalysts

Retrieved on: 
Wednesday, January 6, 2021
Drugs, Psychoactive drugs, Branches of biology, Euphoriants, Morphinans, Phenols, Opiates, Secondary metabolites, Morphine, Heroin, Pain, Ketamine

We enter 2021 focused on building upon the foundation we laid in 2020 to deliver a successful launch for OLINVYK.

Key Points: 
  • We enter 2021 focused on building upon the foundation we laid in 2020 to deliver a successful launch for OLINVYK.
  • Physicians continue to reinforce the value proposition of OLINVYK as a compelling new analgesic option for acute pain patients in the hospital and other controlled clinical settings.
  • The health economic model, which highlights OLINVYK versus IV morphine cost information, is expected to be published in 1H 2021.
  • In addition, the forward-looking statements included in this press release represent the Companys views only as of the date hereof.

Avenue Therapeutics Announces Publication of Tramadol Non-Medical Use in Four European Countries: A Comparative Analysis

Retrieved on: 
Friday, December 18, 2020
Opioids, Drugs, Psychoactive drugs, Euphoriants, Morphinans, Opiates, Secondary metabolites, Prodrugs, Tramadol, Codeine, Morphine, Oxycodone

Despite high availability, tramadol has a low rate of misuse and abuse in the four countries.

Key Points: 
  • Despite high availability, tramadol has a low rate of misuse and abuse in the four countries.
  • Importantly, consistent with previous literature, misuse of tramadol by injection, an important marker of risk behavior, is rare in these countries.
  • Misuse and abuse of tramadol, codeine, morphine, and oxycodone are compared, with national prevalence estimates calculated via calibration weighting.
  • Rocky Mountain Poison & Drug Safety offers research, analysis and surveillance, and consulting through its Research & Consulting Services group, including its industry-leading RADARS system.

Trevena, Inc. Announces Publication Highlighting GI Tolerability Profile of OLINVYK™ (oliceridine) injection in Pain and Therapy

Retrieved on: 
Friday, November 20, 2020
Branches of biology, Drugs, Morphinans, Euphoriants, Opioids, Opiates, Secondary metabolites, Morphine, Vomiting, Antiemetic, Gastrointestinal tract, Heroin

The results of this analysis highlight an improved gastrointestinal (GI) tolerability profile, with OLINVYK demonstrating a ~2-3x likelihood of achieving a complete GI response compared to IV morphine under equianalgesic conditions.

Key Points: 
  • The results of this analysis highlight an improved gastrointestinal (GI) tolerability profile, with OLINVYK demonstrating a ~2-3x likelihood of achieving a complete GI response compared to IV morphine under equianalgesic conditions.
  • A complete GI response is defined as the proportion of patients who complete the study without vomiting and without using any antiemetics.
  • Based on the results of this analysis, OLINVYK has the potential to greatly reduce the risk of nausea and vomiting following surgery, compared to IV morphine.
  • These are compelling findings that suggest the clinical advantages OLINVYK may offer in the post-operative acute care setting.