Flavonoid

The curious link between animal hibernation and ageing – and what humans could learn from it

Retrieved on: 
Friday, January 5, 2024
Animal, Hibernation, Onion, Bread, Dementia, Protein, Metabolism, Life, Glass, Envy, Farmer, Man, Health, Metformin, Organ transplantation, DNA, Medical journal, Inflammation, Chronic kidney disease, Elephant, Lifestyle, Water, Type, Obesity, Food, The BMJ, Gene, Sleep, Radical, Oxidative stress, Longevity, Growth, Patient, Cardiovascular disease, Nature, Deficit spending, History, Flavonoid, Hunting

This long, deep rest is an example of how nature develops clever solution to difficult problems.

Key Points: 
  • This long, deep rest is an example of how nature develops clever solution to difficult problems.
  • In this case, how to survive a long, cold and dark period without much food and water.
  • You will also find descriptions in Inuit Greenlandic stories of a prolonged hibernation-like sleep during the long dark winter months.

Animals and hibernation

  • Animals that hibernate usually live longer compared to other species of the same size.
  • Recent studies using epigenetic clocks, which map activity within genes over time, suggest that hibernation slows down ageing in marmots and bats.
  • So hibernation may hold important clues on how to slow down ageing processes.
  • New science based on epigenetic clocks and lessons from hibernating animals could help us to treat patients who have diseases driven by “wear and tear”.
  • A 2018 study found that mimicking hibernation conditions for the storage of renal grafts from deceased donors seemed to improve their preservation.

Animals and longevity

  • It seems like protection against inflammation, oxidative stress and modifications of proteins that happen with age are mechanism that in general benefit all long-lived animals.
  • Genetic studies of rougheye rockfish, which can live for over 200 years, suggest that a food group called flavonoids is related to longevity.
  • Lessons from nature and hibernating animals tell us that preserving cells, regulation metabolism and genetic adaptions play key roles in longevity.

Forty winks

  • For example, a March 2023 study showed that with good quality sleep, you can add five years to the life of men and two and a half years if you are a woman.
  • How elephants can become so old while sleeping so little is still a mystery to scientists.


Peter Stenvinkel receives funding from Astra Zeneca, Fresenius, Baxter, Novo Nordisk, Bayer, Invizius, Vifor for lectures and scientific advisory boards

What humans can learn from animals about how to adapt to winter

Retrieved on: 
Friday, January 5, 2024
Animal, Hibernation, Onion, Bread, Dementia, Protein, Metabolism, Life, Glass, Envy, Farmer, Man, Health, Metformin, Organ transplantation, DNA, Medical journal, Inflammation, Chronic kidney disease, Elephant, Lifestyle, Water, Type, Obesity, Food, The BMJ, Gene, Sleep, Radical, Oxidative stress, Longevity, Growth, Patient, Cardiovascular disease, Nature, Deficit spending, History, Flavonoid, Hunting

When the cold and dark winter is setting in, some of us envy animals that can hibernate.

Key Points: 
  • When the cold and dark winter is setting in, some of us envy animals that can hibernate.
  • In this case, how to survive a long, cold and dark period without much food and water.
  • You will also find descriptions in Inuit Greenlandic stories of a prolonged hibernation-like sleep during the long dark winter months.

Animals and hibernation

  • Animals that hibernate usually live longer compared to other species of the same size.
  • Recent studies using epigenetic clocks, which map activity within genes over time, suggest that hibernation slows down ageing in marmots and bats.
  • So hibernation may hold important clues on how to slow down ageing processes.
  • New science based on epigenetic clocks and lessons from hibernating animals could help us to treat patients who have diseases driven by “wear and tear”.
  • A 2018 study found that mimicking hibernation conditions for the storage of renal grafts from deceased donors seemed to improve their preservation.

Animals and longevity

  • It seems like protection against inflammation, oxidative stress and modifications of proteins that happen with age are mechanism that in general benefit all long-lived animals.
  • Genetic studies of rougheye rockfish, which can live for over 200 years, suggest that a food group called flavonoids is related to longevity.
  • Lessons from nature and hibernating animals tell us that preserving cells, regulation metabolism and genetic adaptions play key roles in longevity.

Forty winks

  • For example, a March 2023 study showed that with good quality sleep, you can add five years to the life of men and two and a half years if you are a woman.
  • How elephants can become so old while sleeping so little is still a mystery to scientists.


Peter Stenvinkel receives funding from Astra Zeneca, Fresenius, Baxter, Novo Nordisk, Bayer, Invizius, Vifor for lectures and scientific advisory boards

Turning the Tide in Compliance Testing: An Ohio Cannabis Cultivator's Success with the CX-1000 Cannabis Decontamination System

Retrieved on: 
Wednesday, November 29, 2023
Communication, Terpene, Flavonoid, THC, Farm, Medicinal plants, Renewable energy

A newly published case study from VJ Scientific details how Farkas Farms, a family-owned craft cannabis company in Ohio, faced challenges from compliance testing failure despite maintaining top-tier cultivation practices.

Key Points: 
  • A newly published case study from VJ Scientific details how Farkas Farms, a family-owned craft cannabis company in Ohio, faced challenges from compliance testing failure despite maintaining top-tier cultivation practices.
  • In search of a solution, Farkas Farms discovered VJ Scientific's CX-1000, a patent-pending X-ray-based Cannabis Decontamination System that seamlessly integrated into their processes.
  • The CX-1000's dual X-ray sources, increased processing capacity, and ease of operation offered a fresh approach to cannabis decontamination.
  • The success achieved by Farkas Farms underscores the game-changing nature of VJ Scientific's CX-1000 and the company's commitment to transformative solutions.

Acannability™ Launches First Periodic Table of Cannabis Molecules Aimed at Mutual Education Between Consumer and Industry Leaders

Retrieved on: 
Tuesday, November 28, 2023
Cannabinoid, Plant, Language, Meta-analysis, Multimedia, Element, Science, Pharmacist, MBA, Terpene, Flavonoid, Chart, Education, Drug

CHICAGO, Nov. 28, 2023 /PRNewswire/ -- Chicago-based Acannability™, a member-driven, direct to consumer cooperative for the cannabis industry, has announced its creation of a first-of-its-kind Cannabis Periodic Table of Molecules™ chart.

Key Points: 
  • CHICAGO, Nov. 28, 2023 /PRNewswire/ -- Chicago-based Acannability™, a member-driven, direct to consumer cooperative for the cannabis industry, has announced its creation of a first-of-its-kind Cannabis Periodic Table of Molecules™ chart.
  • The table, which was created to mirror the original periodic table of elements, features 51 cannabis molecules and precursor acids arranged into four sections representing the entirety of the plant.
  • Development of this groundbreaking tool was led by Acannability™ Scientific Advisor Joseph Friedman, RPh, MBA, a Medical Cannabis Pharmacist and Pharmacology Expert.
  • "The Acannability™ table was developed to empower consumers with scientific facts of the plants ingredients," states Friedman.

Pharmactive's Aged Black Garlic Extract May Relieve Mild Hypertension in New Study

Retrieved on: 
Monday, October 9, 2023
Cardiovascular disease, Manager, Land treatment unit, Diet, SLU, Stroke, Trial of the century, SAC, Solvent, Hypertension, Risk, Communication, Ageing, Pharmacotherapy, Polyphenol, Black garlic, ABG, Doctor of Philosophy, Blood, System, Heart failure, Research, Clinical trial, Blood pressure, Espinel, Volunteering, Nitric oxide, Nutrient, Flavonoid, Garlic, Patient, Oxidative stress, Pharmaceutical industry, Dietary supplement

MADRID, Oct. 9, 2023 /PRNewswire/ -- Results of a new clinical study have confirmed the blood pressure balancing effect of Pharmactive Biotech Products, SLU's ABG10+®. Aged Black Garlic (ABG10+®) has demonstrated the positive effect in blood pressure in patients exhibiting Grade-1 hypertension receiving prescribed drug treatment.

Key Points: 
  • Aged Black Garlic (ABG10+®) has demonstrated the positive effect in blood pressure in patients exhibiting Grade-1 hypertension receiving prescribed drug treatment.
  • Aged Black Garlic is a whole raw garlic bulb (Allium sativum L) that has been aged under controlled temperatures for a certain period of time.
  • Led by Dr. José Carlos Serrano, Ph.D., the study involved 81 volunteers suffering from Stage 1 hypertension and who were already on blood pressure-reducing medication.
  • "These compounds create the special flavor, aroma, and color of aged black garlic which is why it is a culinary favorite of chefs.

SkinCeuticals Announces the Launch of A.G.E. Advanced Eye

Retrieved on: 
Tuesday, October 3, 2023
Advanced glycation end-product, Caffeine, Face, Sugar, Eye, Glycation, Ageing, Flavonoid, Enoxolone, Eyelid, Patient, Collagen, Advanced Eye Hospital and Institute, Skin, Cosmetics

NEW YORK, Oct. 3, 2023 /PRNewswire/ -- SkinCeuticals, the #1 Medical Skincare Brand1, announces the launch of A.G.E. Advanced Eye, a next-generation corrective eye cream to help reverse visible signs of aging impacted by glycation and collagen decline. The brand has been pioneering anti-glycation skincare since 2008 and recently expanded its glycation-combating portfolio with the introduction of A.G.E. Interrupter Advanced.

Key Points: 
  • Advanced Eye, a next-generation corrective eye cream to help reverse visible signs of aging impacted by glycation and collagen decline.
  • Advanced Eye delivers a breakthrough anti-aging approach to the delicate skin around the eyes, helping visibly reverse advanced signs of aging impacted by glycation, reinforce skin matrix integrity, and immediately brighten the eye area.
  • Advanced Eye as twice daily homecare to all my patients, especially those receiving cosmetic treatments around the eye."
  • Advanced Eye uses the newest groundbreaking technology to address the impact of glycation and collagen decline around the eye area."

Premier Diversified Holdings Inc. Announces Letter of Intent for Acquisition of AJA Health and Wellness Ltd., Assured Diagnosis Inc., and AJA Therapeutics Inc.

Retrieved on: 
Thursday, September 21, 2023
Related party transaction, TSX Venture Exchange, The, AJA, ADI, Aspirin, Policy, News, Wellness, Minority, CT, Letter, Revlon, Inc. v. MacAndrews & Forbes Holdings, Inc., GTA MyCar, Smartphone, Amalgamation, Apigenin, SEDAR, Diagnosis, THC, Medtech, Employment, Health, CAD, DHI, LOI, Nonsteroidal anti-inflammatory drug, Therapy, Flavonoid, ATI, MI, Funding, Bank statement, HBO, Cannabinoid, MRI, PDH, Chronic pain, Security (finance), Health insurance, Bank, Cryptocurrency, Audit, Exchange, Acquisition

VANCOUVER, British Columbia, Sept. 20, 2023 (GLOBE NEWSWIRE) -- Premier Diversified Holdings Inc. ("PDH" or the "Company") (TSXV: PDH) is pleased to announce it has entered into a non-binding letter of intent (the "LOI") among AJA Health and Wellness Ltd. ("AJA Health"), AJA Therapeutics Inc. ("ATI"), Assured Diagnosis Inc. ("ADI"), James Viccars, Elizabeth Bryant Viccars and Deluxe Holdings Inc. ("DHI"), dated September 20, 2023, 2023 (the "Letter of Intent"), pursuant to which, subject to regulatory approval including that of the TSX Venture Exchange (the "Exchange"), PDH intends to acquire (the “AJA Health Acquisition”) all of the issued and outstanding class A common shares (“AJA Class A Shares”) and series 2 preferred shares of AJA Health (“AJA Preferred Shares” and together with the AJA Class A Shares, the “AJA Shares”) and the issued and outstanding shares (the “ADI Shares”) of ADI (the “ADI Acquisition”) by way of share exchange, three-cornered amalgamation or other similar form of transaction, and to acquire all of the shares held by James Viccars, Elizabeth Bryant Viccars and DHI in the capital of ATI in exchange for shares of PDH (the “ATI Share Purchase” and together with the AJA Health Acquisition and the ADI Acquisition, the "Acquisition"). The final structure of the Acquisition is subject to receipt of tax, corporate and securities law advice.

Key Points: 
  • AJA Health and Wellness Ltd.
    AJA Health was incorporated on February 18, 2015 in Alberta under the name MyCare MedTech Inc.
  • AJA Health anticipates completing a private placement of up to 12,500,000 AJA Class A Shares prior to closing of the Acquisition.
  • PDH currently owns 6,015,382 AJA Preferred Shares and 5,144,000 AJA Class A Shares for a total of 11,159,382 AJA Shares and will have 11,278,180 AJA Shares upon the debt settlement with AJA Health which will occur prior to closing of the Acquisition.
  • AJA Health owns 25,000,000 ATI Shares and Each of Jim Viccars, Elizabeth Bryant Viccars and DHI own 500,000 ATI Shares.

Cactus Water: The Super-Hydrating Drink Taking the Beverage Market by Storm - ResearchAndMarkets.com

Retrieved on: 
Thursday, September 21, 2023
Retail, Agriculture, Natural Resources, Food, Beverage, Magnesium, Social media, Health, Nutrient, Inflammation, Muscle fatigue, Nature, Veganism, Growth, Potassium, Flavonoid, Antioxidant, Cochineal

With increasing consumer emphasis on health and wellness, the cactus water market is experiencing a surge in demand.

Key Points: 
  • With increasing consumer emphasis on health and wellness, the cactus water market is experiencing a surge in demand.
  • This plant-based beverage, made from the prickly pear cactus fruit, is being hailed as the super-hydrating solution with myriad health benefits.
  • A rich source of magnesium, potassium, antioxidants, and essential nutrients, cactus water is on its way to becoming the drink of the decade.
  • Social Media Influence: The growing buzz around cactus water on digital platforms contributes significantly to its market visibility and adoption.

Uncle Matt's Organic® Launches Superfruit Punch

Retrieved on: 
Tuesday, September 12, 2023
Sprouts, Taste, Probiotic, Nutrient, SRP, Whole Foods Market, Innovation, Life, Fruit, Marketing, Orange juice, Genetically modified organism, Organic, Simply Orange Juice Company, Polyphenol, Pesticide, Antioxidant, Vitamin C, Ultimate, Family, Flavonoid, Tea, Soft drink

CLERMONT, Fla., Sept. 12, 2023 /PRNewswire/ -- Uncle Matt's Organic®, the nation's #1 selling brand of organic orange juice, is bringing a new functional juice-based beverage to its portfolio. Introducing Uncle Matt's Organic® Superfruit Punch! With its impressive blend of real superfruits, including dark sweet cherries, blueberries, and black elderberry, this delicious beverage will captivate the taste buds of the entire family. The antioxidant boosted beverage is just 45 calories per 8 oz serving and has no cane sugar, preservatives, or added flavors. Uncle Matt's Organic® Superfruit Punch is available now in a 52 oz bottle as well as a shelf-stable 8-pack of 6.75 oz Juice Boxes at select retailers nationwide including Whole Foods and Sprouts and at Shop.UncleMatts.com.

Key Points: 
  • Introducing Uncle Matt's Organic® Superfruit Punch !
  • Uncle Matt's Organic® Superfruit Punch is available now in a 52 oz bottle as well as a shelf-stable 8-pack of 6.75 oz Juice Boxes at select retailers nationwide including Whole Foods and Sprouts and at Shop.UncleMatts.com .
  • "We are thrilled with our newest better-for-you boosted beverage, Uncle Matt's Organic® Superfruit Punch," said Susan McLean, VP of Marketing and Innovation at Uncle Matt's Organic®.
  • With the addition of Uncle Matt's Organic® Superfruit Punch !, there is a functional Uncle Matt's Organic® offering for everyone in the family, including: Ultimate Immune® Organic Orange Juice , Ultimate Defense® Orange Juice with Turmeric and Probiotics , Ultimate Wellness Juice Shots , Uncle Matt's Organic® No Sugar Added Lemonade Juice Boxes , No Sugar Added Strawberry Lemonade Juice Boxes , Orange Light Juice Beverage and Organic Orange Juice with Calcium & Vitamin D in addition to its core Organic Orange Juice , Organic Grapefruit Juice and line of No Sugar Added Lemonades .

Organigram Launches First Range of THCV Products Derived from Moncton-Grown Whole Flower

Retrieved on: 
Monday, August 28, 2023
Cannabis, Natural Resources, Trailblazer, THCV, Senior, Communication, Cannabinoid, Innovation, Multimedia, Appetite, Marketing, Terpene, Organizational chart, OGI, CBD, TSX, THC, Flavonoid, CO2, Video game, Drug, Tea, Phylo (video game)

Organigram Holdings Inc. (NASDAQ: OGI) (TSX: OGI), (the “Company” or “Organigram”), a leading licensed producer of cannabis, is pleased to launch its first range of whole-flower derived THCV products through the Company’s popular SHRED and newly re-launched Trailblazer brands.

Key Points: 
  • Organigram Holdings Inc. (NASDAQ: OGI) (TSX: OGI), (the “Company” or “Organigram”), a leading licensed producer of cannabis, is pleased to launch its first range of whole-flower derived THCV products through the Company’s popular SHRED and newly re-launched Trailblazer brands.
  • Through this investment, Organigram cultivates and extracts THCV in-house in its state-of-the-art Moncton facility and is currently believed to be the only Canadian licensed producer (LP) to do so.
  • Our products are naturally (and not synthetically) derived, not created through chemical processes in a laboratory setting.
  • By harnessing the power of THCV through our strategic investment, we are reshaping the cannabis experience for consumers,” says Megan McCrae, Senior Vice President of Marketing and Communications at Organigram.