Fever

FDA Approves First Cellular Therapy to Treat Patients with Unresectable or Metastatic Melanoma

Retrieved on: 
Friday, February 16, 2024

"Unresectable or metastatic melanoma is an aggressive form of cancer that can be fatal," said Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research (CBER).

Key Points: 
  • "Unresectable or metastatic melanoma is an aggressive form of cancer that can be fatal," said Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research (CBER).
  • Melanoma can spread to other parts of the body if not detected and treated early, resulting in metastatic disease.
  • Treatment for unresectable or metastatic melanoma may include immunotherapy using PD-1 inhibitors, which are antibodies targeting certain proteins in the body to help the immune system fight off cancer cells.
  • Those patients whose melanoma has progressed with these therapies have a high unmet medical need.

FDA Approves First Medication to Help Reduce Allergic Reactions to Multiple Foods After Accidental Exposure

Retrieved on: 
Friday, February 16, 2024

Xolair is intended for repeated use to reduce the risk of allergic reactions and is not approved for the immediate emergency treatment of allergic reactions, including anaphylaxis.

Key Points: 
  • Xolair is intended for repeated use to reduce the risk of allergic reactions and is not approved for the immediate emergency treatment of allergic reactions, including anaphylaxis.
  • "While it will not eliminate food allergies or allow patients to consume food allergens freely, its repeated use will help reduce the health impact if accidental exposure occurs."
  • Current treatment requires strict avoidance of the food(s) the patient is allergic to, and prompt administration of epinephrine to treat anaphylaxis should accidental exposures occur.
  • Xolair is the first FDA-approved medication to reduce allergic reactions to more than one type of food after accidental exposure.

Herbal medicinal product: Polypodii rhizomaArray, C: ongoing call for scientific data

Retrieved on: 
Friday, February 16, 2024

Overview

Key Points: 
  • Overview
    This is a summary of the scientific conclusions reached by the Committee on Herbal Medicinal Products (HMPC) on the medicinal uses of polypody rhizome.
  • The HMPC conclusions are taken into account by EU Member States when evaluating applications for the licensing of herbal medicines containing polypody rhizome.
  • Herbal medicines containing this polypody rhizome preparation are usually available as herbal tea to be drunk or in solid forms to be taken by mouth.
  • Polypody rhizome preparations may also be found in combination with other herbal substances in some herbal medicines.

How worried should I be about cryptosporidiosis? Am I safe at the pool?

Retrieved on: 
Thursday, February 15, 2024

More than 700 cases of this gastrointestinal disease were reported in Queensland in January, which is 13 times more than in January last year.

Key Points: 
  • More than 700 cases of this gastrointestinal disease were reported in Queensland in January, which is 13 times more than in January last year.
  • Read more:
    What lies beneath: the bugs lurking in your swimming pool

What causes cryptosporidiosis, and who is affected?

  • Cryptosporidum hominis only affects humans and is the major cause of recent outbreaks in Australia, while Cryptosporidium parvum can also affect animals.
  • The infection is spread by spores called oocysts in the stools of humans and animals.
  • Cryptosporidiosis is more prevalent in young children, particularly those under five, but the disease can affect people of any age.

So how do we catch it?

  • The largest recorded outbreak occurred in Milwaukee in 1993 where 403,000 people were believed to have been infected.
  • As few as ten oocysts can cause infection, making it possible for contaminated drinking water to affect a very large number of people.
  • Oocysts have been found in foods such as fresh vegetables and seafood but these are not common sources of infection in Australia.

What about chlorine?

  • Young children and in particular children in nappies are known to increase the potential for disease transmission in recreational water.
  • Proper nappy changing, frequent bathroom breaks and showering before swimming to remove faecal residue are helpful ways to reduce the risk.

Some sensible precautions


Other measures you can take to reduce yours and others’ risk of cryptosporidiosis include:
avoid swimming in natural waters such as rivers and creeks during and for at least three days after heavy rain
avoid swimming in beaches for at least one day after heavy rain
avoid drinking untreated water such as water from rivers or springs. If you need to drink untreated water, boiling it first will kill the Cryptosporidium
avoid swallowing water when swimming if you can
if you’ve had diarrhoea, avoid swimming for at least two weeks after it has resolved
avoid sharing towels or linen for at least two weeks after diarrhoea has resolved
avoid sharing, touching or preparing food that other people may eat for at least 48 hours after diarrhoea has resolved
wash your hands with soap and water after going to the bathroom or before preparing food (Cryptosporidium is not killed by alcohol gels and sanitisers).
Not all cases of diarrhoea are due to cryptosporidiosis. There are many other causes of infectious gastroenteritis and because the vast majority of the time recovery is uneventful you don’t need to see a doctor unless very unwell. If you do suspect you may have cryptosporidiosis you can ask your doctor to refer you for a stool test.
Vincent Ho does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

InventHelp Inventors Develop New Fever Pops for Children (AJD-203)

Retrieved on: 
Wednesday, February 14, 2024

Our flavorful design would help reduce fever and pain while also providing added hydration."

Key Points: 
  • Our flavorful design would help reduce fever and pain while also providing added hydration."
  • The patent-pending invention provides a new way to administer ibuprofen or acetaminophen to children.
  • The invention features a unique design that is easy to consume so it is ideal for parents with young children, hospitals, etc.
  • 22-AJD-203, InventHelp, 100 Beecham Drive, Suite 110, Pittsburgh, PA 15205-9801, or call (412) 288-1300 ext.

FSIS RECALL RELEASE 006-2024 SALMONELLA

Retrieved on: 
Tuesday, February 13, 2024

FSIS is working with the Centers for Disease Control and Prevention (CDC) and state public health partners to investigate a multistate outbreak of Salmonella.

Key Points: 
  • FSIS is working with the Centers for Disease Control and Prevention (CDC) and state public health partners to investigate a multistate outbreak of Salmonella.
  • FSIS collected unopened RTE Coppa product as part of the investigation, which tested positive for Salmonella, but that product was not released into commerce.
  • The company conducted a recall of charcuterie products on January 3, 2024 , related to possible Salmonella contamination and FSIS issued a public health alert on January 18, 2024 , related to additional charcuterie products.
  • FSIS routinely conducts recall effectiveness checks to verify recalling firms notify their customers of the recall and that steps are taken to make certain that the product is no longer available to consumers.

FSIS Public Health Alert - Listeria monocytogenes

Retrieved on: 
Friday, February 9, 2024

FSIS is issuing this public health alert to ensure that consumers are aware that these products, which bear the USDA mark of inspection, should not be consumed.

Key Points: 
  • FSIS is issuing this public health alert to ensure that consumers are aware that these products, which bear the USDA mark of inspection, should not be consumed.
  • As more information becomes available, FSIS will update this public health alert.
  • The following products subject to the public health alert are [ view labels ]:
    10.53-oz.
  • The problem was discovered when the firm notified FSIS that they used FDA-regulated cotija cheese that may be contaminated with Listeria monocytogenes to produce burrito products.

KK Strategies: Thailand's Medicinal Herbal Exports Worth Over 2.8 billion USD Annually

Retrieved on: 
Thursday, February 8, 2024

According to The Department of Thai Traditional and Alternative Medicine, Thailand's medicinal herbal exports are between 100 -150 billion baht, or 2.8-4.2 billion USD annually.

Key Points: 
  • According to The Department of Thai Traditional and Alternative Medicine, Thailand's medicinal herbal exports are between 100 -150 billion baht, or 2.8-4.2 billion USD annually.
  • KK Strategies disclosed that Thailand is set for unprecedented growth due to recent government policies supporting the development medicinal herbal industry, particularly for exportation to the United States.
  • This is particularly true for the pain related medicinal herbal exports.
  • KK Strategies highlighted that its valuation for the industry is conservative, taking The Department of Thai Traditional and Alternative Medicine's low end figure of 100 billion baht or 2.8 billion USD annually into account.

Red Door Interactive Wins Gold in "Best Crisis Communications" at 2023 US Agency Awards

Retrieved on: 
Wednesday, February 7, 2024

SAN DIEGO, Feb. 7, 2024 /PRNewswire-PRWeb/ -- Today, Red Door Interactive, a fiercely independent, nationally renowned marketing agency, announced it won US Agency Awards' "Best Crisis Communications" category for its Fever Campaign, in partnership with Children's Hospital of Orange County (CHOC). The agency strategically partnered with CHOC amid the winter season rise of pediatric viral outbreaks, leading to overcrowded emergency rooms and increased strain on CHOC's emergency department. Red Door Interactive's Fever Campaign addressed one of CHOC's most acute challenges: supporting parents with proper fever protocol for their children.

Key Points: 
  • SAN DIEGO, Feb. 7, 2024 /PRNewswire-PRWeb/ -- Today, Red Door Interactive , a fiercely independent, nationally renowned marketing agency, announced it won US Agency Awards ' "Best Crisis Communications" category for its Fever Campaign, in partnership with Children's Hospital of Orange County (CHOC).
  • Red Door Interactive's Fever Campaign addressed one of CHOC's most acute challenges: supporting parents with proper fever protocol for their children.
  • "This campaign aims to equip parents with the necessary information to make informed decisions about their child's care," said Hannah Toy, business manager at at Red Door Interactive.
  • With its potential for scalability, Red Door Interactive's Fever Campaign offers a blueprint for effective marketing and crisis response in pediatric and adult healthcare.

Revive Therapeutics Explores the Use of Bucillamine for Long COVID

Retrieved on: 
Thursday, February 1, 2024

TORONTO, Feb. 01, 2024 (GLOBE NEWSWIRE) -- Revive Therapeutics Ltd. (“Revive” or the “Company”) (OTCQB: RVVTF) (CSE: RVV) (FRANKFURT:31R), a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders, announced today its initiative in Bucillamine, an oral thiol-based drug with anti-inflammatory and antiviral properties, as a potential treatment for long COVID.

Key Points: 
  • TORONTO, Feb. 01, 2024 (GLOBE NEWSWIRE) -- Revive Therapeutics Ltd. (“Revive” or the “Company”) (OTCQB: RVVTF) (CSE: RVV) (FRANKFURT:31R), a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders, announced today its initiative in Bucillamine, an oral thiol-based drug with anti-inflammatory and antiviral properties, as a potential treatment for long COVID.
  • The CDC estimates that 7.5 percent of U.S. adults have long COVID symptoms1.
  • David Cutler, PhD, a professor of economics at Harvard University, estimates in a recent research disclosure that the total economic cost of long COVID could be as much as $3.7 trillion2.
  • These findings uncovered a vulnerability of SARS-CoV-2 to thiol-based drugs and provided a rationale to test thiol-based drugs such as Bucillamine as a novel treatment for COVID-19.