Leicester

RS Oncology Announces New Preclinical Data Show RSO-021 May Block and/or Reverse the Progression of Aggressive Mesotheliomas, Improving Druggability

Retrieved on: 
Wednesday, September 13, 2023
Oncology, Health, Clinical Trials, Research, Science, Pharmaceutical, Biotechnology, Malignant pleural effusion, Tissue, Partnership, AACR, University, Spatial analysis, Neoplasm, Mesothelioma, Survival, EMT, Lung cancer, Multimedia, Photograph, Drug resistance, Oxidative stress, Glycolysis, Patient, Nature, Lunch, RS, University of Leicester, Hypoxia, Conference, Leicester, Pharmaceutical industry

View the full release here: https://www.businesswire.com/news/home/20230912702236/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20230912702236/en/
    “Sarcomatoid tumors are highly resistant to anti-cancer therapies, and many patients run out of available treatment options.
  • Our findings here might have unveiled a druggable ‘Achilles Heel’ against this terrible disease,” said Dr. Fennell, presenting author on the study.
  • (Photo courtesy of George Naumov)
    Mesotheliomas can transform from a less aggressive epithelioid malignancy to a more aggressive sarcomatoid form.
  • RSO-021 treatment reversed the gene signatures associated with epithelial-to-sarcomatoid transition, including downregulation of hypoxia, glycolysis, and epithelial-to-mesenchymal transition (EMT)-associated genes.

Medical students lose their empathy – here's what can be done about it

Retrieved on: 
Wednesday, April 26, 2023
Review, Systematic review, Optimism, University, General Medical Council, Student, Education, Gesture, Hospital, Curriculum, Mid Staffordshire (UK Parliament constituency), Leicester, Shrewsbury and Telford Hospital NHS Trust, Type 2 diabetes, Shock, BioMed Central, Research, Mid Staffordshire NHS Foundation Trust, Death, Patient, University of Leicester, Empathy, Social Problems, Disease, Pharmaceutical industry, Nursing

The Francis report, which investigated the causes of the failings, concluded that a lack of empathy contributed to the catastrophe.

Key Points: 
  • The Francis report, which investigated the causes of the failings, concluded that a lack of empathy contributed to the catastrophe.
  • The Ockenden Report, which investigated the causes of these deaths, stated that lack of empathy exacerbated the problem.
  • Meanwhile, research suggests empathy in doctors may even reduce premature death in patients with type 2 diabetes.
  • In a recently published systematic review, my colleagues and I analysed data from 16 qualitative studies and 771 medical students.
  • However, the remarkable consistency of the identified themes warrants rigorous efforts to reverse the empathy decline.

How to fix the problem


    By bringing the cause of empathy decline to light, our study paves the way for educational programmes that foster, maintain and even enhance empathy in medical students. These interventions are described briefly below.
    • Implementing these empathy interventions is difficult given the pressures on the tightly packed medical school curriculum.
    • Now that we have identified the causes of its deterioration, medical schools can focus on curriculum interventions that enhance it.

Serabi exceeds production guidance for 2022

Retrieved on: 
Tuesday, January 17, 2023
Bismuth, Mineral, Copper, Knowledge, Technical report, Canadian Institute of Mining, Metallurgy and Petroleum, Iron, Mineral resource estimation, Oil, Sale, Leicester, National instrument, ALS, Metal, Khyber Pakhtunkhwa Oil & Gas Company, University, Bachelor of Science, Geology, Coal, Silver, Water, Toronto Stock Exchange, Resource management, Master of Science, Engineering Council, Fellow of the Institute of Materials, Minerals and Mining, Petroleum, Engineering, Vein, NCL, Metallurgy, University of Leicester, European Union (Withdrawal) Act 2018, University of London, Atmosphere, Nature, Gold, Technical, Uranium, Mining, Audit, Palito, Earth, Coringa, EU

The extensive underground exploration drilling programme of 2022 has seen over 17,000 metres of drilling completed.

Key Points: 
  • The extensive underground exploration drilling programme of 2022 has seen over 17,000 metres of drilling completed.
  • This compares with a cash balance of US$10.3 million at the end of September 2022.
  • 2023 PRODUCTION GUIDANCE The Company forecasts combined production from the Palito Complex operations and Coringa Project of between 33,500 and 35,000 ounces of gold during 2023.
  • Serabi closely monitors the performance of its own facility against results from independent laboratory analysis for quality control purpose.

Chip Industry Veteran Dan Harper Appointed Boréas VP of Sales

Retrieved on: 
Wednesday, October 19, 2022
University of Leicester, IOT, Name, Leicester, Warwick Business School, EE Times, Original equipment manufacturer, Texas Instruments, Research, Google, PC, Silego Technology Inc., University, Industry, IP, Awareness, Harvard University, GLOBE, Internet of things, Mobile phone, Renesas Electronics, Logitech, Amazon

BROMONT, Québec, Oct. 19, 2022 (GLOBE NEWSWIRE) -- Boréas Technologies, the semiconductor company commercializing piezo integrated circuits, today announced the appointment of 30-year semiconductor industry veteran Dan Harper as vice president of sales.

Key Points: 
  • BROMONT, Qubec, Oct. 19, 2022 (GLOBE NEWSWIRE) -- Boras Technologies , the semiconductor company commercializing piezo integrated circuits, today announced the appointment of 30-year semiconductor industry veteran Dan Harper as vice president of sales.
  • Throughout his extensive career, Dan has successfully built sales relationships with C-level executives at many of the worlds most influential tech companies, said Simon Chaput, founder and chief executive, Boras Technologies.
  • He is the perfect industry professional to help boost Boras beyond startup-phase to our next level of growth.
  • There are a number of reasons why Boras is a brilliant industry partner, he said.

Palito Exploration Update

Retrieved on: 
Monday, September 26, 2022
Institute, Engineering, University of London, University of Leicester, Master of Science, Southern California Gas Company, Mining, Oil, Nature, Director, Company, Compliance, Mineral, Industry, Leicester, Phrase, Bachelor of Science, Fellow of the Institute of Materials, Minerals and Mining, UK, ALS, Water, University, National instrument, Geology, Atmosphere, Engineering Council, Limestone, Uranium, Audit, Palito

Assay results reported within this release include those provided by the Company's own on-site laboratory facilities at Palito and these will not have been independently verified.

Key Points: 
  • Assay results reported within this release include those provided by the Company's own on-site laboratory facilities at Palito and these will not have been independently verified.
  • Since mid-2019, over 10,000 exploration drill core samples have been assayed at both the Palito laboratory and certified external laboratory, in most cases the ALS laboratory in Belo Horizonte, Brazil.
  • When comparing significant assays with grades exceeding 1 g/t gold, comparison between Palito versus external results record an average over-estimation by the Palito laboratory of 6.7% over this period.
  • Based on the results of this work, the Company's management are satisfied that the Company's own facility shows sufficiently good correlation with independent laboratory facilities for exploration drill samples.

Operational Update

Retrieved on: 
Wednesday, August 17, 2022
Atmosphere, University of London, Industry, Phrase, Leicester, Mineral, Oil, Southern California Gas Company, National instrument, Bachelor of Science, Engineering Council, University of Leicester, Compliance, Institute, Mining, Company, UK, Director, Water, Nature, Fellow of the Institute of Materials, Minerals and Mining, Engineering, Master of Science, University, Geology, ALS, Limestone, Uranium, Audit, Palito

are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.

Key Points: 
  • are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.
  • is the economically mineable part of an Indicated and, in some circumstances, a Measured Mineral Resource demonstrated by at least a Preliminary Feasibility Study.
  • A Proven Mineral Reserve implies a high degree of confidence in the Modifying Factors
    is a weathered or decomposed clay-rich rock.
  • refers to versa time domain electromagnetic, a particular variant of time-domain electromagnetic geophysical survey to prospect for conductive bodies below surface.

Coringa Development Update

Retrieved on: 
Wednesday, June 22, 2022
Industry, Water, Phrase, Geology, Mineral, University of London, Southern California Gas Company, Compliance, Leicester, Institute, Director, Oil, Company, National instrument, UK, University, Master of Science, Bachelor of Science, Mining, Nature, Atmosphere, University of Leicester, Engineering Council, ALS, Engineering, Fellow of the Institute of Materials, Minerals and Mining, Limestone, Uranium, Audit, Palito

are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.

Key Points: 
  • are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.
  • is the economically mineable part of an Indicated and, in some circumstances, a Measured Mineral Resource demonstrated by at least a Preliminary Feasibility Study.
  • A Proven Mineral Reserve implies a high degree of confidence in the Modifying Factors
    is a weathered or decomposed clay-rich rock.
  • refers to versa time domain electromagnetic, a particular variant of time-domain electromagnetic geophysical survey to prospect for conductive bodies below surface.

Production Update

Retrieved on: 
Monday, June 13, 2022
Mining, Southern California Gas Company, University of Leicester, Company, Director, Bachelor of Science, University of London, Nature, Fellow of the Institute of Materials, Minerals and Mining, National instrument, Engineering, Mineral, Engineering Council, University, Master of Science, UK, ALS, Compliance, Atmosphere, Phrase, Geology, Industry, Water, Leicester, Institute, Oil, Limestone, Uranium, Audit, Palito

are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.

Key Points: 
  • are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.
  • is the economically mineable part of an Indicated and, in some circumstances, a Measured Mineral Resource demonstrated by at least a Preliminary Feasibility Study.
  • A Proven Mineral Reserve implies a high degree of confidence in the Modifying Factors
    is a weathered or decomposed clay-rich rock.
  • refers to versa time domain electromagnetic, a particular variant of time-domain electromagnetic geophysical survey to prospect for conductive bodies below surface.

Chinook Therapeutics, IgA Nephropathy Foundation and Komodo Health Collaborate to Provide Nephrologists with Support and Information to Help Reduce Barriers to Diagnosis and Care

Retrieved on: 
Tuesday, April 5, 2022
Komodo, Therapy, A1, Chronic kidney disease, Caregiver, Kidney, Research, SEC, Technology, Nasdaq, GLOBE, Solution, Education, University, Immunoglobulin A, Disease, Urine, Dialysis, Diagnosis, Health, IgA nephropathy, Autoimmune disease, Industry, Hope, LDHA, List of life sciences, Uncertainty, Atrasentan, Leicester General Hospital, Forward-looking statement, Emotion, Approximation error, Nephrology, University of Leicester, Leicester, Awareness, Patient, Primary hyperoxaluria, Waste, Hematuria, Proteinuria, Hospital, Kidney disease, RNA, COVID-19, Blood, Pharmaceutical industry, Medical device, Medicine, Chinook

Through our collaborative efforts with the IgA Nephropathy Foundation as well as our work at Chinook developing atrasentan and BION-1301 for IgA nephropathy, we have learned that the patient journey can be daunting and isolating.

Key Points: 
  • Through our collaborative efforts with the IgA Nephropathy Foundation as well as our work at Chinook developing atrasentan and BION-1301 for IgA nephropathy, we have learned that the patient journey can be daunting and isolating.
  • It is these very challenges facing patients thatserve as a driving force for the IgA Nephropathy Foundation in pursuing its mission.
  • Although we are making strides, IgA nephropathy remains poorly understood and is often misdiagnosed, said Bonnie Schneider, director and co-founder of the IgA Nephropathy Foundation.
  • The IgA Nephropathy Foundation helps patients navigate the important steps necessary to support their kidney health and manage the challenges of living with IgA nephropathy.

Exploration Success Continues at Piaui Prospect

Retrieved on: 
Friday, March 18, 2022
Company, University, Engineering, Fellow of the Institute of Materials, Minerals and Mining, University of London, UK, Compliance, Mining, ALS, Atmosphere, National instrument, Mineral, Questar Corporation (gas company), Industry, Master of Science, Engineering Council, Institute, Oil, University of Leicester, Phrase, Leicester, Geology, Nature, Director, Water, Bachelor of Science, Limestone, Uranium, Audit, Palito

are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.

Key Points: 
  • are near surface bed-rock which has been weathered and oxidised by long term exposure to the effects of water and air.
  • is the economically mineable part of an Indicated and, in some circumstances, a Measured Mineral Resource demonstrated by at least a Preliminary Feasibility Study.
  • A Proven Mineral Reserve implies a high degree of confidence in the Modifying Factors
    is a weathered or decomposed clay-rich rock.
  • refers to versa time domain electromagnetic, a particular variant of time-domain electromagnetic geophysical survey to prospect for conductive bodies below surface.