Diffusion MRI

Longeveron Announces Additional Positive Clinical Data and Imaging Biomarker Results from the CLEAR MIND Phase 2a Trial of Lomecel-B™ in the Treatment of Mild Alzheimer’s Disease

Retrieved on: 
Wednesday, December 20, 2023

The expanded data set reinforced the earlier top-line findings showing that the primary safety endpoint was met and provided further support for Lomecel-B’s positive benefit/risk profile.

Key Points: 
  • The expanded data set reinforced the earlier top-line findings showing that the primary safety endpoint was met and provided further support for Lomecel-B’s positive benefit/risk profile.
  • Wa’el Hashad, CEO of Longeveron, commented: “These new data support our initial results for CLEAR MIND that we announced in October and provide further validation of both the safety and therapeutic potential of Lomecel-B™ in the treatment of mild Alzheimer’s disease.
  • In addition to these clinical findings, brain imaging showed improvement in brain architecture measured by volumetric MRI and DTI, respectively.
  • Taken together, the Company believes the results of the CLEAR MIND study build a strong foundation for further development in mild Alzheimer's disease patients.

Stryker Announces Commercial Launch of Q Guidance System With Cranial Guidance Software

Retrieved on: 
Tuesday, July 11, 2023

Stryker (NYSE: SYK), one of the world’s leading medical technology companies, has commercially launched its Q Guidance System with Cranial Guidance Software to provide surgeons with an image-based planning and intraoperative guidance system that assists in positioning instruments and identifying patient anatomy during cranial surgery.

Key Points: 
  • Stryker (NYSE: SYK), one of the world’s leading medical technology companies, has commercially launched its Q Guidance System with Cranial Guidance Software to provide surgeons with an image-based planning and intraoperative guidance system that assists in positioning instruments and identifying patient anatomy during cranial surgery.
  • View the full release here: https://www.businesswire.com/news/home/20230711948261/en/
    Stryker's Q Guidance System with Cranial Guidance Software includes a touchscreen monitor for control inside/outside the sterile field that provides high-performance 2D-3D visualization.
  • (Photo: Business Wire)
    “With Cranial Guidance Software powered by Q, neurosurgeons have more surgical planning and guidance capabilities than ever before, with a special focus on biopsies and shunt placements,” said Robbie Robinson, president of Stryker’s Spine division.
  • “The new user interface and workflows are slick, and our staff loves the intuitive new views like 3D targeting and the new skull stripping feature.”
    The Q Guidance System with Cranial Guidance Software was used at six early product surveillance sites in May 2023.

Regeneration and Reinnervation of Spinal Cord in Rats Treated with NurExone's Intranasal ExoPTEN

Retrieved on: 
Thursday, June 22, 2023

The image analysis and measurements confirmed successful nerve regeneration following traumatic transection of the spinal cord in rats.

Key Points: 
  • The image analysis and measurements confirmed successful nerve regeneration following traumatic transection of the spinal cord in rats.
  • Subsequently, the spinal cords of rats from the study were subjected to advanced Diffusion Tensor Imaging (DTI) to assess the structural integrity of the spinal cord.
  • ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI) administrated intranasally and yielding neuron regeneration and rewiring in traumatically damaged spinal cords.
  • These DTI tractography images and measurements indicate re-innervation and nourishment to the caudal spinal cords in ExoPTEN rats treated intranasally.

The Flomenhaft Law Firm, PLLC wins hallmark brain imaging litigation discovery victory before the Supreme Court of the State of New York Appellate Division, First Judicial Department

Retrieved on: 
Thursday, June 8, 2023

The Flomenhaft Law Firm, PLLC, www.brainjusticeny.com , won a hallmark victory before the Supreme Court of the State of New York Appellate Division, First Judicial Department in Almonte v. Con Edison Company of New York, Inc., Index No.

Key Points: 
  • The Flomenhaft Law Firm, PLLC, www.brainjusticeny.com , won a hallmark victory before the Supreme Court of the State of New York Appellate Division, First Judicial Department in Almonte v. Con Edison Company of New York, Inc., Index No.
  • The appellate panel reversed the order of the trial court requiring production of various technical data supporting Diffusion Tensor Imaging (“DTI”).
  • DTI is a special sequence of brain MRI used to detect white matter abnormalities.
  • The brain’s white matter furnishes the communication network among the brain’s approximately eight- six billion brain cells.

Total Brain Licenses iSPOT-D for Depression Research to Alto Neuroscience

Retrieved on: 
Wednesday, January 5, 2022

Alto Neuroscience will analyze data from Total Brain's iSPOT-D alongside the company's internally generated biomarker data to inform the ongoing development of Alto's product candidates in depression.

Key Points: 
  • Alto Neuroscience will analyze data from Total Brain's iSPOT-D alongside the company's internally generated biomarker data to inform the ongoing development of Alto's product candidates in depression.
  • Total Brain's license agreement with Alto reflects the extraordinary value of this data.
  • "The scope of Total Brain's unique standardization and complementary datasets are unprecedented," said Dr. Evian Gordon, chairman and chief medical officer, Total Brain.
  • "Total Brain's license agreement with Alto reflects the extraordinary value of this data; and its potential to impact Alto's mission to bring precision medicine to the treatment of depression."

Encyclopedia of Behavioral Neuroscience: Cognitive Psychology, Cognitive Science, Clinical Neurology, Neuroanatomy, and Neurophysiology, Edition No. 2 (2021) - ResearchAndMarkets.com

Retrieved on: 
Thursday, November 25, 2021

2" book from Elsevier Science and Technology has been added to ResearchAndMarkets.com's offering

Key Points: 
  • 2" book from Elsevier Science and Technology has been added to ResearchAndMarkets.com's offering
    Behavioral Neuroscience is a relatively recent discipline which unifies different fields encompassing Cognitive Psychology, Cognitive Science, Clinical Neurology, Neuroanatomy, and Neurophysiology.
  • Published in 2010, it comprised 212 articles and was a unique and essential resource for students and professionals in several fields including neuroscience, psychology, neurology, psychiatry, and cognitive science.
  • It was by far the most comprehensive reference work available addressing the advances in all the field of behavioral neuroscience.
  • Clinical Neuroanatomy (including Diffusion Tensor Imaging), Brain structures and functions (including the senses, biorhythms, plasticity and the perceptual/motor systems)
    2.

3T MRI at Belfair Integrates CorTechs Labs' Latest Software to Support Improved Prostate Cancer Detection

Retrieved on: 
Wednesday, November 11, 2020

BLUFFTON, S.C.and SAN DIEGO, Nov. 11, 2020 /PRNewswire/ -- 3T MRI at Belfair has officially implemented CorTechs Labs' OnQ ProstateTM to advance its radiology interpretations of prostate cancer imaging.

Key Points: 
  • BLUFFTON, S.C.and SAN DIEGO, Nov. 11, 2020 /PRNewswire/ -- 3T MRI at Belfair has officially implemented CorTechs Labs' OnQ ProstateTM to advance its radiology interpretations of prostate cancer imaging.
  • 3T MRI at Belfair was one of the first imaging centers on North America's east coast to implement NeuroQuant , CorTechs Labs' flagship software for advanced volumetric imaging.
  • Today, the imaging center announced its integration of the latest CorTechs Labs product, OnQ Prostate , to support improved detection of clinically significant prostate cancer, made possible through the software's integration of an advanced diffusion MRI technique known as restriction spectrum imaging (RSI).
  • OnQ Prostate is FDA-cleared post-processing software that supports improved prostate cancer detection for a more accurate diagnosis and treatment planning.

  Random Walk Imaging Launches dVIEWR MRI Image Analysis and Workflow Software Platform during ISMRM Conference

Retrieved on: 
Wednesday, August 12, 2020

Random Walk Imaging AB (RWI), a company developing novel software solutions for diffusion magnetic resonance imaging (MRI), today announced the launch of its first commercial software product for clinical researchers and radiologists.

Key Points: 
  • Random Walk Imaging AB (RWI), a company developing novel software solutions for diffusion magnetic resonance imaging (MRI), today announced the launch of its first commercial software product for clinical researchers and radiologists.
  • Bottom: Conventional diffusion MRI map which is not able to resolve the same wealth of actionable information from the MRI signal.
  • With extensive experience in radiotherapy, medical imaging, medical image analysis and machine learning, NONPI Medical strives to create software that is intuitive, innovative and based on actual research needs - Medical Image analysis made easy.
  • Further information can be found at www.nonpimedical.com
    Random Walk Imaging AB is developing a novel proprietary approach to diffusion MRI.

InspireMD Announces Late-Breaking Presentation of Early SIBERIA Clinical Trial Results to be Featured in an e-Course at EuroPCR

Retrieved on: 
Thursday, June 25, 2020

The study evaluated 30-day silent brain infarcts associated with the use of the Acculink conventional open-cell nitinol stent vs the CGuard Micronet-covered stent.

Key Points: 
  • The study evaluated 30-day silent brain infarcts associated with the use of the Acculink conventional open-cell nitinol stent vs the CGuard Micronet-covered stent.
  • Primary endpoints were incidence and volume of new cerebral embolic post-procedural lesions (24-48 hours) as determined by diffusion weighted magnetic resonance imaging (DW-MRI).
  • We are grateful to Prof. Karpenko, Dr. Ignatenko, their colleagues and the patients who made this trial possible.
  • The Company assumes no obligation to publicly update or revise its forward-looking statements as a result of new information, future events or otherwise.

HealthLytix Receives FDA Clearance for Breakthrough Prostate Imaging Solution, RSI-MRI+

Retrieved on: 
Tuesday, November 26, 2019

RSI-MRI+ utilizes a patented advanced diffusion MRI technique called Restriction Spectrum Imaging (RSI) to help improve early detection and diagnosis of prostate cancer by clinicians.

Key Points: 
  • RSI-MRI+ utilizes a patented advanced diffusion MRI technique called Restriction Spectrum Imaging (RSI) to help improve early detection and diagnosis of prostate cancer by clinicians.
  • Many cancers, including prostate cancer, are highly cellular tissues that trap or restrict water.
  • HealthLytix plans to seek FDA clearance for additional body regions in the future.
  • HealthLytix is debuting RSI-MRI+ during the Radiological Society of North America (RSNA) annual meeting taking place Dec. 1-6 in Chicago.