McMaster University

• Dr. Kieran Murphy MD, FRCPC, FSIR, Founder, Inventor, and CMO of Cora Therapeutics, announced the efficacy of a proprietary antioxidant complex in safeguarding DNA from radiation exposure during life-saving aortic aneurysm stenting procedures guided by X-ray technology.
• During these high-intensity image-guided procedures, physicians were administered the antioxidant complex as two capsules, one hour prior to exposure.
• Dr. Murphy's team has successfully demonstrated the protection of mitochondrial DNA from radiation in these subjects, marking a significant milestone in medical literature.
• Considering that mitochondrial DNA is inherited maternally and is 13 times more vulnerable to radiation than nuclear DNA, this achievement holds tremendous promise.

• “Our team significantly advanced toward several key milestones related to new product development as well as strategic corporate initiatives.
• Up to 96 subjects may be included in the study and dosages will escalate from 30 mg to 960 mg according to response.
• Announced positive results from animal studies conducted by Angiogenesis Foundation on a wound healing model.
• Financial Highlights for the First Quarter Ended March 31, 2023
  Total sales of $3,500,000 for the first quarter of 2023 compared to $6,172,000 for the comparative period in 2022.

• Though dementia cannot be prevented and there is currently no cure, adopting healthy lifestyle behaviours can help reduce the risk.
• The Government of Canada is committed to supporting the more than 450,000 Canadians living with diagnosed dementia, their families, and caregivers.
• We are also working with organizations across the country to increase awareness, reduce the risk of developing dementia, reduce stigma, and improve the quality of life of people living with dementia and their caregivers.
• Since 2019, the Government of Canada has announced more than $300 million in funding that supports the national dementia strategy.

• The World Heath Organization (WHO) has declared the end of the global emergency caused by the COVID-19 pandemic.
• Although COVID-19 remains a danger for many, especially with the possibility of new variants, experts are urging that we move forward to prepare for the next pandemic.
• But the pandemic also created the circumstances for a type of global, national and local solidarity that has rarely been seen before.

Caremongering

• A study led by researchers at McMaster University on caremongering Facebook groups found that the majority of posts were to request or offer materials like personal protective equipment, food and clothes or services like picking up groceries and prescriptions.
• There was also a lot of information-sharing about COVID-19, community updates, inspiration and advice.

Pandemic unveiled systemic issues

• Disasters like the pandemic provide an opportunity to examine the exception in order to understand the rule and to expose the unequal social structures that are often hidden in everyday life.
• A University of Guelph study found that in 2020, as the reality of the pandemic set in, discussions in caremonger groups turned towards difficult topics of social justice, inequality and colonization.
• One group organizer who took part in the study shared that she felt COVID-19 unveiled the challenges faced by marginalized people.

A more equitable post-pandemic world

• As the global emergency ends, we need to ask ourselves how a post-pandemic world could be more equitable, just and nurturing.
• The pandemic allowed people to connect with strangers in their neighbourhoods and country through the development of community good will across different geographies.
• Pandemic travel restrictions also produced some positive environmental effects around the world.
• As we reflect on the last three years, let us seize the opportunity to use the experience to create a more equitable, just and nurturing post-pandemic world.