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Applied Materials Announces Q3 FY2023 Earnings Webcast

Retrieved on: 
Friday, August 4, 2023

SANTA CLARA, Calif., Aug. 04, 2023 (GLOBE NEWSWIRE) -- Applied Materials, Inc. will hold a webcast to discuss its third quarter of fiscal 2023 financial results on Thursday, Aug. 17, 2023 at 4:30 p.m.

Key Points: 
  • SANTA CLARA, Calif., Aug. 04, 2023 (GLOBE NEWSWIRE) -- Applied Materials, Inc. will hold a webcast to discuss its third quarter of fiscal 2023 financial results on Thursday, Aug. 17, 2023 at 4:30 p.m.
  • ET / 1:30 p.m. PT.
  • The live webcast will be accessible via the Applied Materials website at: https://ir.appliedmaterials.com .
  • A replay will be available on the same day beginning at 8:00 p.m.

Zenas BioPharma Announces Publication of Phase 2 Study of Obexelimab, an Investigational Treatment for IgG4-Related Disease (IgG4-RD), in The Lancet Rheumatology

Retrieved on: 
Tuesday, August 1, 2023

WALTHAM, Mass., Aug. 01, 2023 (GLOBE NEWSWIRE) -- Zenas BioPharma, a global biopharmaceutical company committed to becoming a leader in the development and commercialization of immune-based therapies, announces The Lancet Rheumatology has published findings from a Phase 2 study evaluating obexelimab for the treatment of patients with IgG4-Related Disease (IgG4-RD). Based on the results of this study, a Phase 3 study in patients with IgG4-RD is ongoing to further investigate the efficacy and safety of obexelimab administered as a subcutaneous injection.

Key Points: 
  • IgG4-RD is a chronic, immune-mediated fibro-inflammatory disease that can affect multiple organs including the major salivary glands, orbits, lacrimal glands, pancreas, biliary tree, lungs, kidneys, and retroperitoneum.
  • Despite its increasing recognition, there remains a need for further research and effective therapeutic options for individuals living with this debilitating disease.
  • Across the world, the use of glucocorticoids is widely considered to be the standard of care for treating IgG4-RD.
  • “Our team is honored to have our research recognized by The Lancet Rheumatology, and we are immensely grateful to the patients who participated in this groundbreaking study.”

Why is Australia having such a warm winter? A climate expert explains

Retrieved on: 
Tuesday, August 1, 2023

If you’ve been out and about the past few days, you may have noticed Australia is experiencing an unseasonably warm winter.

Key Points: 
  • If you’ve been out and about the past few days, you may have noticed Australia is experiencing an unseasonably warm winter.
  • It’s been t-shirt weather across many parts of the country’s east, including Sydney where temperatures topped 25℃ on Sunday.
  • Should we just enjoy the pleasant conditions, or is it a troubling sign of what’s to come under climate change?

The nice weather, explained

    • Since early July, warmer and drier conditions have dominated, due to a high pressure system sitting stubbornly over Australia at the moment.
    • For example, daytime temperatures in Canberra in July – historically known for its cold winters – were the warmest on record, despite frequent frosty mornings.
    • The high pressure has caused the air over the continent’s interior to warm.
    • This is similar to the weather pattern we see in summer when cities such as Adelaide and Melbourne experience their hottest days.
    • Read more:
      Global warming to bring record hot year by 2028 – probably our first above 1.5°C limit

Looking north

    • Ocean temperatures are well above previous record highs for this time of year.
    • Worryingly, a rapid analysis by international experts suggests the extreme heat should not be viewed as unusual, given the effects of climate change.
    • For example, it says China’s recent record-breaking heatwave should now be expected about once in every five years, on average.
    • But the study found climate change significantly contributed to the recent heatwaves in China, North America and Europe.

A sign of what’s to come

    • But Australia’s temperatures are also unusually high for winter – and this is also cause for concern.
    • Warm winters in Australia can negatively affect some parts of the economy, including the ski industry.
    • The warm, dry conditions may also lead to an earlier start to the fire season in Australia’s southeast.

Walker Healthforce Redefines Healthcare Staffing and Consulting

Retrieved on: 
Monday, July 31, 2023

BOSTON, July 31, 2023 /PRNewswire/ -- Walker Healthforce, the newly formed brand resulting from the integration of Walker Healthcare and Walker Healthcare IT, is excited to announce its debut as the leading provider of healthcare IT and clinical solutions. With end-to-end healthcare consulting services and a renewed vision, Walker Healthforce is set to redefine staffing and consulting solutions in the healthcare industry, offering unparalleled value to the workforce, healthcare payers, and clinical ecosystems.

Key Points: 
  • Walker Healthcare and Walker Healthcare IT rebrand as Walker Healthforce, revolutionizing the industry through expertise and innovation in healthcare nursing, IT and allied health solutions
    BOSTON, July 31, 2023 /PRNewswire/ -- Walker Healthforce, the newly formed brand resulting from the integration of Walker Healthcare and Walker Healthcare IT, is excited to announce its debut as the leading provider of healthcare IT and clinical solutions.
  • With end-to-end healthcare consulting services and a renewed vision, Walker Healthforce is set to redefine staffing and consulting solutions in the healthcare industry, offering unparalleled value to the workforce, healthcare payers, and clinical ecosystems.
  • Under the leadership of Founder and CEO Tifiany Walker, Walker Healthforce has dedicated nearly two decades to transforming healthcare through specialized services.
  • "We are delighted to introduce Walker Healthforce as the result of our years' of expertise in the healthcare domain," said Tifiany Walker.

Penetron Concrete Waterproofing Protects New Elementary School Classrooms in Mississippi

Retrieved on: 
Friday, July 28, 2023

EAST SETAUKET, N.Y., July 28, 2023 /PRNewswire-PRWeb/ -- The $1.6 million addition of two new classrooms at the Laurel Upper Elementary School in Laurel, Mississippi, was completed at the end of July 2023, in time for the start of the new school year. PENETRON ADMIX SB, a crystalline waterproofing admixture, was specified to protect all concrete elements exposed to groundwater from deterioration.

Key Points: 
  • PENETRON ADMIX SB, a crystalline waterproofing admixture, was specified to protect all concrete elements exposed to groundwater from deterioration.
  • PENETRON ADMIX SB , a crystalline waterproofing admixture, was specified to protect all concrete elements exposed to groundwater from deterioration.
  • The Penetron Group is a leading manufacturer of specialty construction products for concrete waterproofing, concrete repairs, and floor preparation systems.
  • As an integral waterproofing solution, PENETRON ADMIX SB provides low permeability, low shrinkage and crack self-healing properties, a highly effective combination for exposed concrete structures.

4 factors driving 2023's extreme heat and climate disasters

Retrieved on: 
Thursday, July 27, 2023

Between the record-breaking global heat and extreme downpours, it’s hard to ignore that something unusual is going on with the weather in 2023.

Key Points: 
  • Between the record-breaking global heat and extreme downpours, it’s hard to ignore that something unusual is going on with the weather in 2023.
  • People have been quick to blame climate change – and they’re right, to a point: Human-caused global warming does play the biggest role.
  • A recent study determined that the weekslong heat wave in Texas and Mexico that started in June 2023 would have been virtually impossible without it.

How El Niño is involved

    • El Niño is a climate phenomenon that occurs every few years when surface water in the tropical Pacific reverses direction and heats up.
    • This happened in 2016, the time of the last strong El Niño.
    • A weak El Niño also occurred in 2019-2020, contributing to 2020 becoming the world’s second-warmest year.
    • El Niño’s opposite, La Niña, involves cooler-than-usual Pacific currents flowing westward, absorbing heat out of the atmosphere, which cools the globe.

Solar fluctuations

    • Earth’s temperature increase during a solar maximum, compared with average solar output, is only about 0.09 F (0.05 C), roughly a third of a large El Niño.
    • However, unlike the variable and unpredictable El Niño changes, the 11-year solar cycle is comparatively regular, consistent and predictable.
    • The last solar cycle hit its minimum in 2020, reducing the effect of the modest 2020 El Niño.

A massive volcanic eruption

    • In an unusual twist, the largest volcanic eruption of the 21st century so far, the 2022 eruption of Tonga’s Hunga Tonga-Hunga Ha’apai is having a warming and not cooling effect.
    • The eruption released an unusually small amount of cooling sulfate aerosols but an enormous amount of water vapor.
    • Water vapor is a powerful greenhouse gas, and the eruption may end up warming Earth’s surface by about 0.06 F (0.035 C), according to one estimate.

Underlying it all: Global warming

    • All of this comes on top of anthropogenic, or human-caused, global warming.
    • Humans have raised global average temperatures by about 2 F (1.1 C) since 1900 by releasing large volumes of greenhouse gases into the atmosphere.
    • The warming from greenhouse gases is actually greater than 2 F (1.1 C), but it has been masked by other human factors that have a cooling effect, such as air pollution.

What does this mean for the future?

    • According to climate modeling, this would likely mean even more heat waves, forest fires, flash floods and other extreme weather events.
    • Unfortunately, climate modeling shows that as temperatures continue to increase, weather events get more extreme.
    • Because of the unfortunate timing of several parts of the climate system, it seems that the odds are not in our favor.

As heat records fall, how hot is too hot for the human body?

Retrieved on: 
Wednesday, July 19, 2023

Extreme heat has been breaking records across Europe, Asia and North America, with millions of people sweltering in heat and humidity well above “normal” for days on end.

Key Points: 
  • Extreme heat has been breaking records across Europe, Asia and North America, with millions of people sweltering in heat and humidity well above “normal” for days on end.
  • Death Valley hit a temperature of 128 degrees Fahrenheit (53.3 degrees Celsius) on July 16, 2023 – not quite the world’s hottest day on record, but close.
  • Heat waves are becoming supercharged as the climate changes – lasting longer, becoming more frequent and getting just plain hotter.

The limits of human adaptability

    • Scientists and other observers have become alarmed about the increasing frequency of extreme heat paired with high humidity.
    • In the Middle East, Asaluyeh, Iran, recorded an extremely dangerous maximum wet-bulb temperature of 92.7 F (33.7 C) on July 16, 2023 – above our measured upper limit of human adaptability to humid heat.
    • It was not until recently that this limit was tested on humans in laboratory settings.

The PSU H.E.A.T. Project

    • These experiments provide insight into which combinations of temperature and humidity begin to become harmful for even the healthiest humans.
    • Each participant swallowed a small telemetry pill that continuously monitored their deep body or core temperature.
    • They then sat in an environmental chamber, moving just enough to simulate the minimal activities of daily living, such as showering, cooking and eating.
    • That would equal 87 F at 100% humidity or 100 F (38 C) at 60% humidity.

Dry vs. humid environments

    • In hot, dry environments the critical environmental limits aren’t defined by wet-bulb temperatures, because almost all the sweat the body produces evaporates, which cools the body.
    • However, the amount humans can sweat is limited, and we also gain more heat from the higher air temperatures.
    • Keep in mind that these cutoffs are based solely on keeping your body temperature from rising excessively.

How to stay safe

    • W. Larry Kenney receives research grant funding from the National Institutes of Health/National Institute on Aging.
    • Daniel Vecellio is supported by a training grant from the National Institute on Aging through the Penn State Center for Healthy Aging.
    • Rachel Cottle is supported by a training grant from the National Institute on Aging through the Penn State Center for Healthy Aging.

As a summer heat wave pummels the US, an expert warns about the dangers of humidity – particularly for toddlers, young athletes and older adults

Retrieved on: 
Monday, July 17, 2023

So we’ll have more hot days and more extremely hot days, which result in an increased frequency, duration and intensity of environmental heat waves.

Key Points: 
  • So we’ll have more hot days and more extremely hot days, which result in an increased frequency, duration and intensity of environmental heat waves.
  • Kenney: The primary means by which humans get rid of body heat that’s built up is by evaporation of sweat.
  • Why are infants and older adults particularly vulnerable to heat and humidity?
  • So individuals on both ends of the age spectrum tend to be particularly vulnerable to what we term classic heatstroke.
  • Is the heat index a good measurement of how hot it feels and how people’s bodies are affected by heat?
  • It doesn’t account for radiation from the Sun, for example‚ but it’s much better than the heat index because it’s much more physiological.
  • Watch the full interview to hear more about how heat and humidity affect your health.

Janus Henderson Corporate Debt Index: Company Debts Reach New Record but Appetite to Borrow Is Waning

Retrieved on: 
Wednesday, July 12, 2023

Verizon, the US telecoms company, became the most indebted non-financial company in the world in 2022/23 for the first time.

Key Points: 
  • Verizon, the US telecoms company, became the most indebted non-financial company in the world in 2022/23 for the first time.
  • Overall Janus Henderson expects net debt to decline by 1.9% this year, falling to $7.65 trillion.
  • Janus Henderson Investors is the name under which investment products and services are provided by Janus Henderson Investors International Limited (reg no.
  • Janus Henderson and Knowledge Shared are trademarks of Janus Henderson Group plc or one of its subsidiaries.

Does the direction water rotates down the drain depend on which hemisphere you're in? Debunking the Coriolis effect in your sink

Retrieved on: 
Monday, July 10, 2023

A presenter will position three buckets of water – one in the Northern Hemisphere, one in the Southern Hemisphere, and one directly on the equator – and let the water drain out.

Key Points: 
  • A presenter will position three buckets of water – one in the Northern Hemisphere, one in the Southern Hemisphere, and one directly on the equator – and let the water drain out.
  • Tourists are shown that, as the water drains, the water in the northern bucket rotates in one direction, the water in the southern bucket rotates in the other direction, and the water at the equator doesn’t rotate at all.
  • The demonstrator might claim that this strange phenomenon is governed by physics, that it’s an example of the Coriolis effect.

The math behind the phenomenon

    • Roughly, the Navier-Stokes equations relate the change of fluid velocity – how the fluid moves – to the forces acting on the fluid, subject to a few physical constraints.
    • For example, the equations assume that the overall amount of fluid in the system doesn’t change over time.
    • Although there is no known complete solution to Navier-Stokes equations, meteorologists and physical oceanographers can still obtain useful partial solutions.

What happens in your sink?

    • The Rossby number compares the dynamics of the fluid with the Earth’s rotation rate, taking into account how big the system is and how fast it’s moving.
    • A small Rossby number indicates that the Coriolis force has a strong effect on the system, while a large Rossby number signifies that the Coriolis force has a negligible effect.
    • So even though the way water swirls down the drain may be consistent, that isn’t due to the Coriolis effect.

So what did the tourists see?

    • Given the size of the system, physical oceanographers can comfortably conclude that the Coriolis force is not responsible for what the tourists see in those buckets or bowls.
    • Although physical oceanographers can’t deny what the tourists see, we know that the magic trick isn’t due to the Coriolis effect at such a small scale.