AM

Pillar Biosciences to Present New Scientific Data at Association for Molecular Pathology Annual Meeting

Retrieved on: 
Wednesday, November 8, 2023
Pillar, Laboratory, NSCLC, Liquid biopsy, AMP, IVD, Bandwidth (signal processing), Microsatellite instability, Automation, MSI, Neoplasm, Research, Microdissection, AM, Beckman Coulter, Detection, Chemistry, Test management, UMI, RUO, Methylation, NGS, Targeted molecular therapy for neuroblastoma, CRC, Health care, Partnership, HRD, Urinary cell-free DNA, Column, Pension fund, Medical imaging, Instrumentation, Multiplexing

NATICK, Mass., Nov. 8, 2023 /PRNewswire/ -- Pillar Biosciences, Inc., the leader in Decision Medicine™, today announced the company and scientific collaborators will collectively present eleven studies and two corporate workshops at the 2023 Association for Molecular Pathology (AMP) Annual Meeting from November 14 -18, 2023 in Salt Lake City, UT (Booth #619).

Key Points: 
  • NATICK, Mass., Nov. 8, 2023 /PRNewswire/ -- Pillar Biosciences, Inc., the leader in Decision Medicine™, today announced the company and scientific collaborators will collectively present eleven studies and two corporate workshops at the 2023 Association for Molecular Pathology (AMP) Annual Meeting from November 14 -18, 2023 in Salt Lake City, UT (Booth #619).
  • "Pillar Biosciences is committed to developing the data necessary to support the quality, accuracy and value of our leading IVD & RUO kitted products which can be used locally by laboratories to perform NGS sequencing," said Randy Pritchard, CEO of Pillar Biosciences, Inc. "We are proud to present these data in partnership with our collaborators at this year's AMP Annual Meeting as we continue to enable more laboratories globally with NGS assays that can be performed in a low-cost, high-multiplexed manner, thus enabling actionable, accessible NGS profiling results."
  • The scientific data presented at AMP will focus on Pillar Biosciences oncoReveal™ Research-Use-Only (RUO) kitted NGS products for liquid biopsy (LBx), HRD, methylation, solid tumor and automation.
  • Localized NGS-based Methylation Testing to Help Inform BioPharma Clinical Trials and Improve Patient Care in Oncology (Room 251F: 8:00-8:50 AM MDT)
    Highly Accurate and Automated NGS assays for Efficient Localized LBx and TBx Clinical Testing in Oncology (Room 251F: 9:00-9:51 AM MDT)
    Comparative Laboratory Performance Evaluation of Pillar Biosciences, ArcherDx, and ThermoFisher Sequencing Chemistries for The Targeted Characterization of CRC & NSCLC Samples (Poster Number: ST120)
    Robust Low Frequency Somatic Variant Detection in cfDNA Using a SLIMamp® Based Liquid Biopsy Assay (Poster Number: ST035)
    Detection of Microsatellite Instability (MSI) Using oncoReveal Core LBx, a Multiplexed, Single Tube, Liquid Biopsy Assay (Poster Number: ST107)
    Automation of The Pillar Biosciences oncoReveal Solid Tumor 22 gene panel (ORST22) on the Biomek NGeniuS Next Generation Library Prep System (Poster Number: ST029)
    QCPRECISE!™: An Automated Spatially Targeted Microdissection Platform Driven by AI Guided Digital Pathology Improves Extracted Solid Tumor DNA Purity Relative to Conventional Macrodissection (Poster Number: TT007)
    To UMI or Not to UMI: Obtaining Robust Low-Frequency Variant Identification for Liquid Biopsy with a SLIMamp-Based NGS Chemistry Without Molecular Barcoding (Poster Number: ST145)
    Robust Bioinformatic Method for Estimating Tumor Content in cfDNA Using Denoised Target Sequencing (Poster Number: I031)
    Pillar Biosciences oncoReveal methylQuant Panels: Accurate and Easy-to-Use Methylation NGS Assays Leveraging SLIMamp Technology (Poster Number: ST031)
    oncoReveal Fusion LBx: Single-Tube Multiplexed PCR-Based NGS assay for Detection of Multiple Gene Fusions from Cell Free RNA (Poster Number: ST041)
    Robust Detection of Copy Number Amplifications Using Pillar's oncoReveal™ Core LBx Panel with Low Input from Liquid Biopsy Samples (Poster Number: I011)
    Poster and abstract summaries of this research will be available onsite at Pillar Biosciences' booth #619.

ELEGOO Unveils Game-Changing Solutions for Big 3D Printing Ambitions at Formnext 2023

Retrieved on: 
Wednesday, November 8, 2023
3D, FDM, Life, Kickstarter, Research, AM, Multimedia, Growth, USD, CMO, 3D printing, Messe Frankfurt

Notable highlights include the global debut of the cutting-edge Jupiter SE resin 3D printer and the OrangeStorm Giga, an impressive large FDM industrial printer.

Key Points: 
  • Notable highlights include the global debut of the cutting-edge Jupiter SE resin 3D printer and the OrangeStorm Giga, an impressive large FDM industrial printer.
  • With these groundbreaking innovations, ELEGOO is set to redefine 3D printing, delivering advanced features and unparalleled performance.
  • The OrangeStorm Giga printer delivers size, speed, precision, and quality to enable creators to bring their boldest 3D printing ideas to life.
  • This exhibit served as a demonstration of the extensive applications of ELEGOO's 3D printing technology across diverse industries.

ELEGOO Unveils Game-Changing Solutions for Big 3D Printing Ambitions at Formnext 2023

Retrieved on: 
Wednesday, November 8, 2023
3D, FDM, Life, Kickstarter, Research, AM, Growth, USD, CMO, 3D printing, Messe Frankfurt

Notable highlights include the global debut of the cutting-edge Jupiter SE resin 3D printer and the OrangeStorm Giga, an impressive large FDM industrial printer.

Key Points: 
  • Notable highlights include the global debut of the cutting-edge Jupiter SE resin 3D printer and the OrangeStorm Giga, an impressive large FDM industrial printer.
  • With these groundbreaking innovations, ELEGOO is set to redefine 3D printing, delivering advanced features and unparalleled performance.
  • The OrangeStorm Giga printer delivers size, speed, precision, and quality to enable creators to bring their boldest 3D printing ideas to life.
  • This exhibit served as a demonstration of the extensive applications of ELEGOO's 3D printing technology across diverse industries.

RTI to Exhibit and Present at I/ITSEC Conference 2023

Retrieved on: 
Tuesday, November 7, 2023
Booth, Data Distribution Service, MDO, Secure, Conference, PM, OMG, Interservice/Industry Training, Simulation and Education Conference, AM, Orange County Convention Center, Environment, RTI, Distribution, Simulation, Video game

SUNNYVALE, Calif., Nov. 07, 2023 (GLOBE NEWSWIRE) -- Real-Time Innovations (RTI) , the largest software framework company for autonomous systems, will be exhibiting and presenting at the Interservice/Industry Training, Simulation and Education Conference (I/ITSEC) 2023, the world's largest modeling simulation and training (MS&T) event, taking place November 27 – December 1 in the Orange County Convention Center.

Key Points: 
  • SUNNYVALE, Calif., Nov. 07, 2023 (GLOBE NEWSWIRE) -- Real-Time Innovations (RTI) , the largest software framework company for autonomous systems, will be exhibiting and presenting at the Interservice/Industry Training, Simulation and Education Conference (I/ITSEC) 2023, the world's largest modeling simulation and training (MS&T) event, taking place November 27 – December 1 in the Orange County Convention Center.
  • At Booth #2020, RTI will showcase RTI Connext® and demonstrate a cockpit experience in an integration of multiple systems, simulating a FACE™ certifiable solution.
  • Connext is the leading interoperability framework for the MS&T industry with expertise spanning security, cloud, gaming, and real-time embedded systems.
  • Connext increases fidelity in today’s training systems while supporting the DoD’s vision for data-centricity – using data at speed and scale for operation advantage and increased efficiency.

AM Best Revises Outlooks to Positive for Members of IFG Companies

Retrieved on: 
Tuesday, November 7, 2023
Professional Services, Insurance, Finance, AM Best, Credit, News, AM, FSR, Risk management, ERM, ALL

AM Best has revised the outlooks to positive from stable and affirmed the Financial Strength Rating (FSR) of A (Excellent) and the Long-Term Issuer Credit Ratings (Long-Term ICRs) of “a+” (Excellent) for the members of IFG Companies (IFG) (Burlington, NC).

Key Points: 
  • AM Best has revised the outlooks to positive from stable and affirmed the Financial Strength Rating (FSR) of A (Excellent) and the Long-Term Issuer Credit Ratings (Long-Term ICRs) of “a+” (Excellent) for the members of IFG Companies (IFG) (Burlington, NC).
  • (See below for a detailed listing of the members and Credit Ratings [ratings]).
  • The revision of the outlooks to positive from stable is driven by IFG’s operating performance, which has shown sustained improvement in underwriting and operating profitability since 2021.
  • IFG also has been the beneficiary of high persistency, adherence to price adequacy, minimal volatility, favorable loss reserve development and disciplined expense management.

Takeda Announces Late-Breaking Data from Phase 2b Study of TAK-279, an Investigational, Oral, Once-Daily TYK2 Inhibitor, in Patients with Active Psoriatic Arthritis at American College of Rheumatology Convergence Annual Meeting

Retrieved on: 
Tuesday, November 7, 2023
Health, Other Health, Clinical Trials, Research, Science, Pharmaceutical, Biotechnology, C-reactive protein, Headache, American College, TAK, MDA, PGA, MD, Research and development, Skin, Inflammation, AM, Ulcerative colitis, Psoriasis Area and Severity Index, Rash, MACR, Lower respiratory tract infection, Lupus, Common, American College of Rheumatology, Body surface area, Safety, Patient, ACR, BSA, Abstract, PASI, TYK2, Pharmaceutical industry, Copper, Takeda, Psoriasis

These data ( Abstract #L12 ) will be presented on Tuesday, November 14 as part of the late-breaking poster session from 9:00 AM - 11:00 AM PT at the American College of Rheumatology (ACR) Convergence 2023 in San Diego, California.

Key Points: 
  • These data ( Abstract #L12 ) will be presented on Tuesday, November 14 as part of the late-breaking poster session from 9:00 AM - 11:00 AM PT at the American College of Rheumatology (ACR) Convergence 2023 in San Diego, California.
  • There was no clinically significant difference in adverse event rates between doses of TAK-279.
  • “We are also advancing the development of TAK-279 in Crohn’s disease, ulcerative colitis and systemic lupus erythematosus and exploring a range of other potential indications.
  • These opportunities are being explored in parallel with the psoriasis and psoriatic arthritis programs.”

AM Best Affirms Credit Ratings of Tokio Marine HCC Mexico Compañía Afianzadora, S.A. de C.V.

Retrieved on: 
Tuesday, November 7, 2023
Banking, Professional Services, Insurance, Finance, Tokio Marine HCC, Tokio Marine, TMX, Policy, AM Best, Credit, News, MXN, AM, ERM, Risk, USD, S.A, ALL, Risk management, Reinsurance, Bank, HC

AM Best has affirmed the Financial Strength Rating of A (Excellent), the Long-Term Issuer Credit Rating of “a” (Excellent) and the Mexico National Scale Rating of “aaa.MX” (Exceptional) of Tokio Marine HCC Mexico Compañía Afianzadora, S.A. de C.V. (TMHCC Mexico) (Mexico City, Mexico).

Key Points: 
  • AM Best has affirmed the Financial Strength Rating of A (Excellent), the Long-Term Issuer Credit Rating of “a” (Excellent) and the Mexico National Scale Rating of “aaa.MX” (Exceptional) of Tokio Marine HCC Mexico Compañía Afianzadora, S.A. de C.V. (TMHCC Mexico) (Mexico City, Mexico).
  • HC and TMHCC Mexico also have a sister company, Tokio Marine Compañía de Seguros, S.A. de C.V. (TMX), which is domiciled in Mexico.
  • For additional information regarding the use and limitations of Credit Rating opinions, please view Guide to Best’s Credit Ratings .
  • For information on the proper use of Best’s Credit Ratings, Best’s Performance Assessments, Best’s Preliminary Credit Assessments and AM Best press releases, please view Guide to Proper Use of Best’s Ratings & Assessments .

AM Best Affirms Credit Ratings of Family Guardian Insurance Company Limited and FamGuard Corporation Limited

Retrieved on: 
Tuesday, November 7, 2023
Insurance, Professional Services, Good, AM Best, Credit, News, AM, ERM, Family, ALL, Security (finance), Risk management

AM Best has affirmed the Financial Strength Rating of B++ (Good) and the Long-Term Issuer Credit Rating (Long-Term ICR) of “bbb+” (Good) of Family Guardian Insurance Company Limited (Family Guardian).

Key Points: 
  • AM Best has affirmed the Financial Strength Rating of B++ (Good) and the Long-Term Issuer Credit Rating (Long-Term ICR) of “bbb+” (Good) of Family Guardian Insurance Company Limited (Family Guardian).
  • Concurrently, AM Best has affirmed the Long-Term ICR of “bb+” (Fair) of FamGuard Corporation Limited (FamGuard).
  • For additional information regarding the use and limitations of Credit Rating opinions, please view Guide to Best's Credit Ratings .
  • For information on the proper use of Best’s Credit Ratings, Best’s Performance Assessments, Best’s Preliminary Credit Assessments and AM Best press releases, please view Guide to Proper Use of Best’s Ratings & Assessments .

AM Best Assigns Indicative Issue Credit Ratings to Elevance Health, Inc.’s New Shelf Registrations

Retrieved on: 
Tuesday, November 7, 2023
Insurance, Professional Services, Good, ELV, AM Best, NYSE, Tax, Elevance Health, Credit, News, Acquisition, AM, ALL, Bank

AM Best has assigned indicative Long-Term Issue Credit Ratings of “bbb” (Good) to subordinated issues, “bbb-” (Good) to preferred stock issues and “bbb+” (Good) to senior unsecured issues on the recently filed shelf registrations of Elevance Health, Inc. (Elevance Health) (Indianapolis, IN) [NYSE: ELV].

Key Points: 
  • AM Best has assigned indicative Long-Term Issue Credit Ratings of “bbb” (Good) to subordinated issues, “bbb-” (Good) to preferred stock issues and “bbb+” (Good) to senior unsecured issues on the recently filed shelf registrations of Elevance Health, Inc. (Elevance Health) (Indianapolis, IN) [NYSE: ELV].
  • Concurrently, AM Best has withdrawn the ratings of the previous shelf registration, which expired.
  • For additional information regarding the use and limitations of Credit Rating opinions, please view Guide to Best's Credit Ratings .
  • For information on the proper use of Best’s Credit Ratings, Best’s Performance Assessments, Best’s Preliminary Credit Assessments and AM Best press releases, please view Guide to Proper Use of Best’s Ratings & Assessments .

AM Best Downgrades Issuer Credit Rating of Kot Insurance Company AG

Retrieved on: 
Tuesday, November 7, 2023
Finance, Data Analytics, Banking, Professional Services, Insurance, Good, AM Best, PEMEX, Credit, News, Pemex, AM, FSR, Risk management, Risk, ALL, Reinsurance

AM Best has downgraded the Long-Term Issuer Credit Rating (Long-Term ICR) to “bbb” (Good) from “bbb+” (Good) and affirmed the Financial Strength Rating (FSR) of B++ (Good) of Kot Insurance Company AG (Kot) (Switzerland).

Key Points: 
  • AM Best has downgraded the Long-Term Issuer Credit Rating (Long-Term ICR) to “bbb” (Good) from “bbb+” (Good) and affirmed the Financial Strength Rating (FSR) of B++ (Good) of Kot Insurance Company AG (Kot) (Switzerland).
  • The downgrading of the Long-Term ICR reflects the further deterioration of PEMEX’s credit profile since AM Best’s last rating review.
  • For additional information regarding the use and limitations of Credit Rating opinions, please view Guide to Best’s Credit Ratings .
  • AM Best is a global credit rating agency, news publisher and data analytics provider specialising in the insurance industry.