Vertex

Royalty Pharma Reports Q4 and Full Year 2023 Results

Retrieved on: 
Thursday, February 15, 2024

In October 2023, Royalty Pharma drew $350 million under its existing unsecured revolving credit facility, which was repaid during the fourth quarter of 2023.

Key Points: 
  • In October 2023, Royalty Pharma drew $350 million under its existing unsecured revolving credit facility, which was repaid during the fourth quarter of 2023.
  • Royalty Pharma began repurchasing its Class A ordinary shares in April 2023 under a $1.0 billion multi-year share repurchase program.
  • During the fourth quarter of 2023, Royalty Pharma announced new transactions of up to $1.6 billion.
  • Royalty Pharma will host a conference call and simultaneous webcast to discuss its fourth quarter and full year 2023 results today at 8:00 a.m., Eastern Time.

European Commission Approves First CRISPR/Cas9 Gene-Edited Therapy, CASGEVY™ (exagamglogene autotemcel), for the Treatment of Sickle Cell Disease (SCD) and Transfusion-Dependent Beta Thalassemia (TDT)

Retrieved on: 
Tuesday, February 13, 2024

ZUG, Switzerland and BOSTON, Feb. 13, 2024 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, announced today that the European Commission has granted conditional marketing authorization to CASGEVY™ (exagamglogene autotemcel [exa-cel]), a CRISPR/Cas9 gene edited therapy. CASGEVY is approved for the treatment of patients who are 12 years of age and older with severe sickle cell disease (SCD) characterized by recurrent vaso-occlusive crises (VOCs) or transfusion-dependent beta thalassemia (TDT), for whom hematopoietic stem cell (HSC) transplantation is appropriate and a human leukocyte antigen matched related HSC donor is not available.

Key Points: 
  • “The approval by the European Commission is yet another important regulatory milestone underscoring the potentially transformative benefit of CASGEVY for patients with severe sickle cell disease and transfusion-dependent beta thalassemia,” said Samarth Kulkarni, Chairman and Chief Executive Officer of CRISPR Therapeutics.
  • Vertex is working closely with national health authorities in the European Union (EU) to secure access for eligible patients as quickly as possible.
  • Through this work, they have secured early access for eligible TDT patients in France ahead of the national reimbursement process.
  • There are currently three activated ATCs in the EU with plans to activate a total of approximately 25 centers across Europe.

Vertex Global Survey Reveals the Regions Championing and Struggling with Indirect Tax Compliance, With the U.S. Taking the Lead

Retrieved on: 
Monday, February 12, 2024

Vertex surveyed 580 indirect tax decision makers (representing global companies with annual revenue of at least $50 million) and asked each to categorise themselves according to their indirect tax performance, ranging from 'champion’ (best) to ‘crawler’ (worst).

Key Points: 
  • Vertex surveyed 580 indirect tax decision makers (representing global companies with annual revenue of at least $50 million) and asked each to categorise themselves according to their indirect tax performance, ranging from 'champion’ (best) to ‘crawler’ (worst).
  • 43% of U.S. organisations marked themselves as ‘champions’, meaning their business is protected and future-proofed with an efficient technology led approach.
  • Across Europe, there are numerous drivers causing businesses to take a more cautious approach to managing indirect tax compliance.
  • The adoption of tax technology solutions has also played a role in separating ‘champion’ regions from ‘crawler’ regions.

Trina Solar Vertex S+ 505W n-type dual-glass modules enter mass production

Retrieved on: 
Thursday, February 8, 2024

As part of the Vertex S+ series specifically designed for commercial and industrial rooftops, Vertex S+ 505W just made its debut in Europe at the Trina Solar booth at Genera in Spain on February 6.

Key Points: 
  • As part of the Vertex S+ series specifically designed for commercial and industrial rooftops, Vertex S+ 505W just made its debut in Europe at the Trina Solar booth at Genera in Spain on February 6.
  • The Vertex S+ 505W, guided by higher power yet lower BOS and LCOE, is tailored to meet a customer core requirement of shorter payback time.
  • Trina Solar's Vertex S+ series modules have been highly recognized in the non-utility market by industry partners and customers.
  • The mass production of Vertex S+ 505W will guarantee subsequent full delivery to Europe, Australia, the Asia-Pacific and other regions.

Trina Solar Vertex S+ 505W n-type dual-glass modules enter mass production

Retrieved on: 
Thursday, February 8, 2024

As part of the Vertex S+ series specifically designed for commercial and industrial rooftops, Vertex S+ 505W just made its debut in Europe at the Trina Solar booth at Genera in Spain on February 6.

Key Points: 
  • As part of the Vertex S+ series specifically designed for commercial and industrial rooftops, Vertex S+ 505W just made its debut in Europe at the Trina Solar booth at Genera in Spain on February 6.
  • The Vertex S+ 505W, guided by higher power yet lower BOS and LCOE, is tailored to meet a customer core requirement of shorter payback time.
  • Trina Solar's Vertex S+ series modules have been highly recognized in the non-utility market by industry partners and customers.
  • The mass production of Vertex S+ 505W will guarantee subsequent full delivery to Europe, Australia, the Asia-Pacific and other regions.

Vertex's Bradd Wildstein Recognized as a 2024 CRN® Channel Chief

Retrieved on: 
Tuesday, February 6, 2024

The designation recognizes IT vendors and distribution executives who drive strategy and set the channel agenda for their companies.

Key Points: 
  • The designation recognizes IT vendors and distribution executives who drive strategy and set the channel agenda for their companies.
  • Wildstein and his team built out a cross-functional partner enablement organization and formalized the Vertex Global Partner Program.
  • "I am incredibly honored to be recognized as a 2024 CRN® Channel Chief.
  • The Channel Company is pleased to acknowledge these prominent channel leaders and looks forward to chronicling their achievements throughout the year.”

Vertex Announces Positive Results From Pivotal Trials of Vanzacaftor/Tezacaftor/Deutivacaftor, Next-In-Class Triple Combination Treatment for Cystic Fibrosis

Retrieved on: 
Monday, February 5, 2024

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced positive results from its once-daily vanzacaftor/tezacaftor/deutivacaftor (the “vanza triple”) program, the most comprehensive Phase 3 pivotal program ever conducted by Vertex for the treatment of cystic fibrosis (CF), a progressive, multi-organ disease caused by dysfunction of the CFTR protein.

Key Points: 
  • Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced positive results from its once-daily vanzacaftor/tezacaftor/deutivacaftor (the “vanza triple”) program, the most comprehensive Phase 3 pivotal program ever conducted by Vertex for the treatment of cystic fibrosis (CF), a progressive, multi-organ disease caused by dysfunction of the CFTR protein.
  • In both SKYLINE 102 and SKYLINE 103, the primary endpoint of absolute change from baseline in ppFEV1 through week 24 was met and showed that treatment with vanza triple was non-inferior to treatment with TRIKAFTA.
  • The results from other secondary endpoints were consistent with results of the primary and key secondary endpoints.
  • Treatment with the vanza triple was well tolerated in all three studies, and the safety was similar between the vanza triple and TRIKAFTA treatment groups in SKYLINE 102 and SKYLINE 103.

Vertex to Announce Fourth Quarter 2023 Financial Results on Thursday, February 29, 2023

Retrieved on: 
Friday, February 2, 2024

KING OF PRUSSIA, Pa., Feb. 01, 2024 (GLOBE NEWSWIRE) -- Vertex, Inc. (NASDAQ:VERX), a leading global technology provider of indirect tax solutions, today announced that it will release fourth quarter 2023 financial results before the market opens on Thursday, February 29, 2023.

Key Points: 
  • KING OF PRUSSIA, Pa., Feb. 01, 2024 (GLOBE NEWSWIRE) -- Vertex, Inc. (NASDAQ:VERX), a leading global technology provider of indirect tax solutions, today announced that it will release fourth quarter 2023 financial results before the market opens on Thursday, February 29, 2023.
  • A conference call to discuss the results will be held at 8:30 a.m. Eastern Time that same day.
  • Those wishing to participate may do so by dialing 1-412-317-6026 approximately ten minutes prior to start time.
  • A listen-only webcast of the call will also be available through the Company’s Investor Relations website at https://ir.vertexinc.com .

World Wetlands Day | Trina Solar unleashes solar power to safeguard human well-being

Retrieved on: 
Friday, February 2, 2024

The spotlight of Trina Solar's impactful initiatives is the transformation of the saline wetlands in Houzhen, Shandong province, once vulnerable and barren.

Key Points: 
  • The spotlight of Trina Solar's impactful initiatives is the transformation of the saline wetlands in Houzhen, Shandong province, once vulnerable and barren.
  • Houzhen's success serves as a precursor to Trina Solar's transforming the saline wetlands of Yangkou, less than 40 kilometers away.
  • Trina Solar, guided by its mission of "Solar Energy for All," remains unwavering in providing tailor-made smart energy solutions for large-scale applications like wetlands.
  • Trina Solar stands firm in safeguarding the environment and advancing human well-being through sustainable initiatives.

World Wetlands Day | Trina Solar unleashes solar power to safeguard human well-being

Retrieved on: 
Friday, February 2, 2024

The spotlight of Trina Solar's impactful initiatives is the transformation of the saline wetlands in Houzhen, Shandong province, once vulnerable and barren.

Key Points: 
  • The spotlight of Trina Solar's impactful initiatives is the transformation of the saline wetlands in Houzhen, Shandong province, once vulnerable and barren.
  • Houzhen's success serves as a precursor to Trina Solar's transforming the saline wetlands of Yangkou, less than 40 kilometers away.
  • In Haiyan Town, Guangdong province, Trina Solar supplied all modules in the first phase of the 100MW PV project.
  • Trina Solar, guided by its mission of "Solar Energy for All," remains unwavering in providing tailor-made smart energy solutions for large-scale applications like wetlands.