Denali

Denali Therapeutics Reports Third Quarter 2023 Financial Results and Business Highlights

Retrieved on: 
Tuesday, November 7, 2023
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SOUTH SAN FRANCISCO, Calif., Nov. 07, 2023 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (Nasdaq: DNLI), a biopharmaceutical company developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for the treatment of neurodegenerative diseases and lysosomal storage diseases, today reported financial results for the third quarter ended September 30, 2023, and provided business highlights.

Key Points: 
  • SOUTH SAN FRANCISCO, Calif., Nov. 07, 2023 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (Nasdaq: DNLI), a biopharmaceutical company developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for the treatment of neurodegenerative diseases and lysosomal storage diseases, today reported financial results for the third quarter ended September 30, 2023, and provided business highlights.
  • Denali has selected five ASO targets for further development and is focused on advancing two OTV candidates towards clinical development.
  • 2023 Guidance on Operating Expenses:
    Cash, cash equivalents, and marketable securities were approximately $1.12 billion as of September 30, 2023.
  • General and administrative expenses were $25.3 million and $23.3 million for the three months ended September 30, 2023 and 2022, respectively.

Holland America Line's Black Friday Sale Features Prepaid Crew Appreciation and Up to 30% Off Cruise Fares

Retrieved on: 
Tuesday, November 7, 2023
Black Friday Sale, Canaletto, Sport, Black, Beer, Coffee, News, Holland America Line, Black Friday, Denali, America Line, Black Friday (shopping), Wine, Tourism, Antarctica

SEATTLE, Nov. 7, 2023 /PRNewswire/ -- Cruisers can get an early start shopping for the holiday season with Holland America Line's Black Friday Sale that runs from Nov. 17 to Dec. 1, 2023. Guests who book select cruises through 2025 will receive prepaid stateroom crew appreciation, resulting in an added value of up to nearly $700 per person depending on the length of sailing. Black Friday promotional sailings also feature discounts of up to 30% off cruise-only fares.

Key Points: 
  • Guests who want to add even more value to their cruise can combine the Black Friday offer with Holland America Line's popular Have It All premium cruise package.
  • "Black Friday is synonymous with the best holiday season deals, and Holland America Line's Black Friday Sale is no exception," said Beth Bodensteiner, chief commercial officer for Holland America Line.
  • "With included crew appreciation and reduced cruise fares, guests can take advantage of significant savings.
  • Depending on the ship and cruise duration, guests can indulge in Holland America Line's award-winning specialty dining for up to three nights.

Momentum in Alzheimer's Research Guided by the Biology of Aging to be Highlighted in Session Moderated by Alzheimer's Drug Discovery Foundation at 2023 Clinical Trials on Alzheimer's Disease Conference

Retrieved on: 
Tuesday, October 17, 2023
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NEW YORK, Oct. 17, 2023 /PRNewswire/ -- The Alzheimer's Drug Discovery Foundation (ADDF) will be moderating a session, "Emerging Solutions: Novel Approaches to Treating Alzheimer's Disease," at the 2023 Clinical Trials on Alzheimer's Disease (CTAD) conference, which will be held October 24th through 27th at Boston Park Plaza in Boston, Massachusetts.

Key Points: 
  • This session will highlight the biology of aging and promising drugs in the pipeline that are targeting the many underlying aging pathologies contributing to the onset of Alzheimer's.
  • This is timely, as 75% of Alzheimer's drugs in clinical trials are exploring novel targets beyond amyloid and tau.
  • The session will also feature innovative research on regenerative therapies for Alzheimer's as well as novel approaches for targeting inflammation.
  • The panel will discuss the strategic investments needed to accelerate the recent momentum in the field, which is critical for fast-tracking the next generation of Alzheimer's therapeutics.

Exclusive Offer Will Give California Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, World Heritage Site, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush National Historical Park, Drink, Klondike Gold Rush, UNESCO, Denali, Zaandam, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for California residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for California residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Exclusive Offer Will Give Texas Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, World Heritage Site, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush, Drink, UNESCO, Denali, Zaandam, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Texas residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Texas residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Exclusive Offer Will Give Wisconsin Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, World Heritage Site, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush, Drink, UNESCO, Denali, Zaandam, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Wisconsin residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Wisconsin residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Exclusive Offer Will Give Illinois Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, World Heritage Site, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush, Drink, UNESCO, Denali, Zaandam, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Illinois residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Illinois residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Exclusive Offer Will Give Michigan Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, World Heritage Site, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush, Drink, UNESCO, Denali, Zaandam, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Michigan residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Michigan residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Exclusive Offer Will Give Florida Residents Spending Money for Holland America Line's 2024 Alaska Cruisetours to the Yukon

Retrieved on: 
Tuesday, October 10, 2023
HAL, Denali National Park and Preserve, Have It All, Glacier Discovery, USD, Travel, Holland America Line, America Line, MS Koningsdam, CAD, EXC, History, Klondike Gold Rush National Historical Park, Drink, Klondike Gold Rush, UNESCO, Denali, World Heritage Site, Zaandam, Hotel, Tourism, Interior design, MS Noordam

SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Florida residents. This limited-time promotion runs from Oct. 13 to Nov. 15 and will provide $150 of bonus spending money per person when booking select 2024 Yukon & Denali Cruisetours. This $150 credit also can be combined with Holland America Line's "Have It All" premium package that features a shore excursion, beverage package, specialty dining and Wi-Fi at special pricing.

Key Points: 
  • SEATTLE, Oct. 10, 2023 /PRNewswire/ -- Holland America Line is gearing up for the 2024 Alaska season with an exclusive offer just for Florida residents.
  • Holland America Line is the only cruise line that extends the Alaska Cruisetours up to the unspoiled reaches of Canada's Yukon Territory.
  • With six different Cruisetours to the Yukon in 2024, guests can choose to cruise to Alaska or travel overland first.
  • Holland America Line's Cruisetours combine an Alaska cruise with an inland journey to Denali and the Yukon.

Karina Brez Launches the Cowgirl LUV Collection, a Tribute to America's Majestic Mountains

Retrieved on: 
Tuesday, September 26, 2023
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NEW YORK, Sept. 26, 2023 /PRNewswire-PRWeb/ -- A tribute to the untamed spirit of the American West, renowned equestrian jewelry designer Karina Brez unveils her latest signature collection, Cowgirl LUV, an ode to the inspiring mountains and cities that grace the landscape of the USA. The collection pays homage to the rugged beauty of the American West, featuring stackable rings that artfully symbolize various mountain ranges, and a thoughtful double entendre, with each mountain range doubling as a cowgirl name, embodying the spirit of adventure and independence.

Key Points: 
  • Western charm meets everyday luxury in Karina Brez's new signature collection, Cowgirl LUV, which echoes the vibrant landscapes of the USA.
  • Cowgirl LUV is a symbol of tradition and a nod to the enduring legacy of Western fashion.
  • The Cowgirl LUV collection by Karina Brez invites one to embark on a journey through captivating landscapes, spirited names, and places that define the heart of America.
  • For more information about the Cowgirl LUV collection and to explore the full range of Karina Brez's equestrian designs, visit karinabrez.com .