Study Links "Stuck" Stem Cells to Hair Turning Gray
This means that during normal hair growth, such cells continually move back and forth on the maturity axis as they transit between compartments of the developing hair follicle.
- This means that during normal hair growth, such cells continually move back and forth on the maturity axis as they transit between compartments of the developing hair follicle.
- The researchers found that as hair ages, sheds, and then repeatedly grows back, increasing numbers of McSCs get stuck in the stem cell compartment called the hair follicle bulge.
- "Our study adds to our basic understanding of how melanocyte stem cells work to color hair," said study lead investigator Qi Sun, PhD, a postdoctoral fellow at NYU Langone Health.
- For example, transit-amplifying hair follicle cells never revert to their original stem cell state.