Cofactors

BridgeBio Pharma’s Origin Biosciences Presents New Data on the Natural History of Molybdenum Cofactor Deficiency (MoCD) Type A at the Society of the Study of Inborn Errors of Metabolism (SSIEM) Conference

Retrieved on: 
Thursday, September 5, 2019
Chemistry, Enzymes, Physical sciences, Organophosphates, Cofactors, Pteridines, Molybdenum cofactor deficiency, Cyclic pyranopterin monophosphate, Pterin, Molybdenum, Tyrosine hydroxylase, MOCS1

The majority of patients had MoCD Type A (n=37), followed by MoCD Type B (n=16) and Other (n=12).

Key Points: 
  • The majority of patients had MoCD Type A (n=37), followed by MoCD Type B (n=16) and Other (n=12).
  • Nearly all patients (n=57) had first presenting symptoms by Day 28 with median onset for MoCD Type A patients at 2days.
  • 2Mechler K, Mountford WK, Hoffmann GF, Ries M. Ultra-orphan diseases: a quantitative analysis of the natural history of molybdenum cofactor deficiency.
  • Efficacy and safety of cyclic pyranopterin monophosphate substitution in severe molybdenum cofactor deficiency type A: a prospective cohort study.

Veravas Launches Product Portfolio to Mitigate Biotin Interference and Improve Diagnostic Assay Accuracy

Retrieved on: 
Thursday, July 11, 2019
Biotechnology, General Health, Health, Medical devices, Hospitals, Other Health, Chemistry, Organic compounds, Physical sciences, Biotin, Cofactors, Ureas, Molecular binding, Streptavidin

Veravas, Inc. , an emerging diagnostic company, launched a portfolio of products that can improve the accuracy of current diagnostic test results by helping laboratory professionals detect and manage biotin interference in patient samples with VeraTest Biotin and VeraPrep Biotin.

Key Points: 
  • Veravas, Inc. , an emerging diagnostic company, launched a portfolio of products that can improve the accuracy of current diagnostic test results by helping laboratory professionals detect and manage biotin interference in patient samples with VeraTest Biotin and VeraPrep Biotin.
  • VeraTest Biotin and VeraPrep Biotin offer immediate solutions to address biotin interference in existing diagnostic tests.
  • VeraTest Biotin is a digital qualitative test that screens for biotin interference in less than five minutes.
  • This antibody retains a high binding affinity to conjugated biotin with a low binding affinity to free biotin, thus eliminating the impact of biotin interference on test results.

Precision BioLogic's CRYOcheck™ Factor VIII Inhibitor Kit Cleared for Sale in U.S.

Retrieved on: 
Wednesday, March 13, 2019
Coagulation system, Proteins, Branches of biology, Recombinant proteins, Cofactors, Factor VIII, Factor VII, Reaction inhibitor

The presence of factor VIII (FVIII) inhibitors reduces therapy effectiveness and is one of the most complex and costly complications for people with hemophilia A.

Key Points: 
  • The presence of factor VIII (FVIII) inhibitors reduces therapy effectiveness and is one of the most complex and costly complications for people with hemophilia A.
  • Precision BioLogic developed the CRYOcheckFactor VIII Inhibitor Kit to address this challenge.
  • A modified Nijmegen-Bethesda assay is used to determine FVIII inhibitor levels in people with hemophilia A.
  • According to Paul Empey, President & CEO of Precision BioLogic, FDA 510(k) clearance of the CRYOcheckFactor VIII Inhibitor Kit is an exciting milestone for the company but more importantly, a step forward for patient care.

Precision BioLogic Launches Product to Improve Inhibitor Testing for People With Hemophilia A

Retrieved on: 
Monday, February 11, 2019
Branches of biology, Natural sciences, Coagulation system, Chemistry, Cofactors, Factor VIII, Assay

Precision BioLogic developed the CRYOcheckFactor VIII Inhibitor Kit to address this challenge.

Key Points: 
  • Precision BioLogic developed the CRYOcheckFactor VIII Inhibitor Kit to address this challenge.
  • A modified Nijmegen-Bethesda assay is used to determine FVIII inhibitor levels in people with hemophilia A.
    Paul Empey, President & CEO of Precision BioLogic, notes that the launch of the CRYOcheckFactor VIII Inhibitor Kit is an important step forward for patient care.
  • "Enhancing patient care is at the core of everything we do at Precision BioLogic," he says.
  • Validation of Nijmegen-Bethesda assay modifications to allow inhibitor measurement during replacement therapy and facilitate inhibitor surveillance.J Thromb Haemost2012; 10: 1055-1061.

SynTech Nutrition's SynTsize Recovery Post-Workout Shake Coming to America

Retrieved on: 
Thursday, January 24, 2019
Organic compounds, Branches of biology, Exercise physiology, Physical exercise, Chemical compounds, Antioxidants, Cofactors, Eli Lilly and Company, Lipoic acid, Metabolic window

"It's crucial to have a high-quality post-workout shake during the anabolic window after a workout," said Bob Wigman of SynTech.

Key Points: 
  • "It's crucial to have a high-quality post-workout shake during the anabolic window after a workout," said Bob Wigman of SynTech.
  • SynTsize Recovery features 47g of carbohydrates in a blend of fast carbs that quickly replenish the body's carbohydrate stocks after a workout.
  • Other important ingredients in SynTsize Recovery include 2g of Crea-Trona, 2g of beta-alanine and 200mg of alpha-lipoic acid.
  • To learn more about SynTech's products, including SynTsize Recovery, visit the company's website at www.syntech-nutrition.com .

Global Nucleic Acid Labeling Market 2018-2023 by Label Type, Technique, Application and Geography

Retrieved on: 
Tuesday, October 2, 2018
Biology, Chemistry, Biochemistry, Molecular biology, Biotin, Cofactors, Ureas, Nucleic acid, Aminoallyl nucleotide, Biotinylation

The "Global Nucleic Acid Labeling Market - Segmented by Label Type (Biotin-based, Fluorescent, Radioactive, and Others), by Technique, by Application, and by Geography - Growth, Trends, and Forecast (2018 - 2023)" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Nucleic Acid Labeling Market - Segmented by Label Type (Biotin-based, Fluorescent, Radioactive, and Others), by Technique, by Application, and by Geography - Growth, Trends, and Forecast (2018 - 2023)" report has been added to ResearchAndMarkets.com's offering.
  • The Nucleic Acid Labeling market is expected to register a CAGR of 9% over the forecast period.
  • Nucleic acid labeling is a procedure in which nucleic acids are modified or attached with tags that enable their detection or purification.
  • Common labels used to generate nucleic acid probes include biotin, radioactive phosphates, fluorophores, and enzymes.

Bayer Receives FDA Approval for Jivi®, New Hemophilia A Treatment With Step-Wise Prophylaxis Dosing Regimen

Retrieved on: 
Friday, August 31, 2018
Coagulation system, Recombinant proteins, Health, Biology, Biotechnology, Cofactors, Factor VIII, Bayer, Factor VII, Food and Drug Administration

The FDA also approved Jivi for on-demand treatment and the perioperative management of bleeding in the same population.

Key Points: 
  • The FDA also approved Jivi for on-demand treatment and the perioperative management of bleeding in the same population.
  • Jivi works by replacing the reduced or missing factor VIII (FVIII) in adults and adolescents 12 years of age or older with hemophilia A.
  • Treatment with Jivi was well tolerated in the majority of adult and adolescent patients in clinical trials.
  • Bayer has also submitted marketing authorization applications for BAY94-9027 for the treatment of hemophilia A in the European Union and Japan.

Bayer Receives FDA Approval for Jivi®, New Hemophilia A Treatment With Step-Wise Prophylaxis Dosing Regimen

Retrieved on: 
Thursday, August 30, 2018
Coagulation system, Recombinant proteins, Health, Biology, Biotechnology, Cofactors, Factor VIII, Bayer, Factor VII, Food and Drug Administration

The FDA also approved Jivi for on-demand treatment and the perioperative management of bleeding in the same population.

Key Points: 
  • The FDA also approved Jivi for on-demand treatment and the perioperative management of bleeding in the same population.
  • Jivi works by replacing the reduced or missing factor VIII (FVIII) in adults and adolescents 12 years of age or older with hemophilia A.
  • Treatment with Jivi was well tolerated in the majority of adult and adolescent patients in clinical trials.
  • Bayer has also submitted marketing authorization applications for BAY94-9027 for the treatment of hemophilia A in the European Union and Japan.

Alpha Lipoic Acid Market in Asia Pacific to see 7%+ CAGR to 2024

Retrieved on: 
Friday, August 3, 2018
Carboxylic acids, Antioxidants, Cofactors, Eli Lilly and Company, Lipoic acid, Chemistry, Organic chemistry

SELLBYVILLE, Del., Aug. 3, 2018 /PRNewswire-iReach/ -- The world trends report says, " Alpha Lipoic Acid Market is poised to exceed USD 19 million by 2024.

Key Points: 
  • SELLBYVILLE, Del., Aug. 3, 2018 /PRNewswire-iReach/ -- The world trends report says, " Alpha Lipoic Acid Market is poised to exceed USD 19 million by 2024.
  • Prevailing trends for diabetic people primarily in China, Australia and India has resulted in rising product demand to manufacture medical drugs which in turn will boost alpha lipoic acid market by 2024.
  • R-lipoic acid led the global alpha lipoic acid market and accounted for over 80% business in 2016.
  • in the region which will help generate significant revenue for the alpha lipoic acid market by 2024.

Big Developments at AACC 2018 - New Alzheimer's Test, Chagas Detection, Faster Microbiology and New Molecular POC and B12 Testing Improvements

Retrieved on: 
Monday, July 30, 2018
Nutrition, RTT, Vitamin B12, B vitamins, Hematopathology, Cofactors, Health, Cobalamin, Anemia, Vitamin

Chagas Test: Chagas is spread by insects nicknamed "kissing bugs," but symptoms are anything but benign.

Key Points: 
  • Chagas Test: Chagas is spread by insects nicknamed "kissing bugs," but symptoms are anything but benign.
  • Several studies support that holoTC is a better indicator of vitamin B12 status than total serum cobalamin for anemia detection.
  • holoTC is the only form of vitamin B12 that is taken up and used by cells of the body.
  • SHERLOCK Gene Editing Update: AACC will once again be a central point for gene editing and its potential use in diagnostics.