Homeostasis

GRI Bio Announces Partnership with the Respiratory Translational Research Collaboration to Advance Leading NKT Regulation Technology Targeting Earlier in the Inflammatory Cascade to Modulate Disease Progression

Retrieved on: 
Tuesday, October 17, 2023

LA JOLLA, CA, Oct. 17, 2023 (GLOBE NEWSWIRE) -- GRI Bio, Inc. (NASDAQ: GRI) (“GRI Bio” or the “Company”), a biotechnology company advancing an innovative pipeline of Natural Killer T (“NKT”) cell modulators for the treatment of inflammatory, fibrotic and autoimmune diseases, today announced it has entered into a collaboration with the UK consortia, National Institute for Health and Care Research Respiratory Translational Research Collaboration (“NIHR Respiratory TRC”) to advance its leading NKT regulation technology to treat inflammatory, fibrotic and autoimmune diseases.

Key Points: 
  • Together with the NIHR Respiratory TRC, GRI Bio will design and execute complex multi-center studies that accelerate research for the benefit of respiratory disease patients.
  • “As a Company, we are dedicated to revolutionizing the way that inflammatory, fibrotic and autoimmune diseases like IPF are treated.
  • The establishment of this collaboration represents another important step forward as we work to advance our clinical development programs.
  • The NIHR Respiratory TRC offers cutting-edge translational research that we believe will assist in executing clinical studies underpinned by excellent scientific rigor.

Amolyt Pharma Announces Data on Prevalence of Bone Disease in Patients with Hypoparathyroidism and Favorable Bone Effects of Eneboparatide at the American Society for Bone and Mineral Research (ASBMR) 2023 Annual Meeting

Retrieved on: 
Monday, October 16, 2023

LYON, France, and CAMBRDIGE, Mass., Oct. 16, 2023 (GLOBE NEWSWIRE) -- Amolyt Pharma, a global company specialized in developing therapeutic peptides for rare endocrine and related diseases, today announced data from two posters that were presented at the American Society for Bone and Mineral Research (ASBMR) 2023 Annual Meeting, which is being held October 13-16, 2023, in Vancouver, BC, Canada. The data include a prospective analysis of bone disease in patients with hypoparathyroidism from the Canadian National Hypoparathyroidism Registry with evidence of significant bone disease burden in postmenopausal females (PMF). In addition, data from both pre-clinical and clinical studies of eneboparatide continue to demonstrate its ability to restore balanced bone turnover, preserving bone integrity, while maintaining calcium homeostasis and normalizing urinary calcium.

Key Points: 
  • The data include a prospective analysis of bone disease in patients with hypoparathyroidism from the Canadian National Hypoparathyroidism Registry with evidence of significant bone disease burden in postmenopausal females (PMF).
  • In addition, data from both pre-clinical and clinical studies of eneboparatide continue to demonstrate its ability to restore balanced bone turnover, preserving bone integrity, while maintaining calcium homeostasis and normalizing urinary calcium.
  • “We’re very pleased to have a strong presence at this year’s ASBMR Annual Meeting.
  • These data increase our understanding of the relationship between hypoparathyroidism and bone strength.

Lily Jan and Eve Marder to receive 2023 Pearl Meister Greengard Prize

Retrieved on: 
Friday, September 15, 2023

NEW YORK, Sept. 15, 2023 /PRNewswire/ -- Groundbreaking neuroscientists Lily Jan and Eve Marder will jointly receive the 2023 Pearl Meister Greengard Prize, an award which recognizes outstanding women scientists.

Key Points: 
  • NEW YORK, Sept. 15, 2023 /PRNewswire/ -- Groundbreaking neuroscientists Lily Jan and Eve Marder will jointly receive the 2023 Pearl Meister Greengard Prize, an award which recognizes outstanding women scientists.
  • "This year's awardees are two outstanding scientists who have made fundamental contributions to neurobiology," says Michael W. Young , Richard and Jeanne Fisher Professor, Nobel Laureate, and chair of the Pearl Meister Greengard Prize selection committee.
  • Marder, most recognized for her work understanding the modulation of neural networks, is the Victor and Gwendolyn Beinfield University Professor at Brandeis University.
  • To attend the Pearl Meister Greengard Prize ceremony and learn more about the award, register here .

Study Validating MoA of Intranasal Foralumab in Alzheimer’s Disease Published in the Prestigious Journal PNAS, Following FDA IND Clearance

Retrieved on: 
Wednesday, September 6, 2023

Remarkably, we found this benefit occurred independent of reduction of amyloid beta plaque in the brain.

Key Points: 
  • Remarkably, we found this benefit occurred independent of reduction of amyloid beta plaque in the brain.
  • This represents a unique approach to treating Alzheimer’s disease that could also potentially be employed in combination with anti-amyloid therapy.
  • Alzheimer's disease is a neurodegenerative disease characterized by amyloid beta (Aβ) plaques, neurofibrillary tangles, and microglial activation.
  • In this study, mice were treated three times a week with intranasal anti-CD3 for five months and compared against isotype control or saline.

Italfarmaco Group Receives EMA Validation of Marketing Authorization Application for Givinostat in Duchenne Muscular Dystrophy

Retrieved on: 
Tuesday, September 5, 2023

Italfarmaco Group announced today that its Marketing Authorization Application (MAA) for Givinostat as a potential treatment for Duchenne Muscular Dystrophy (DMD) has been submitted to the European Medicine Agency (EMA) and that the EMA has started its regulatory review process.

Key Points: 
  • Italfarmaco Group announced today that its Marketing Authorization Application (MAA) for Givinostat as a potential treatment for Duchenne Muscular Dystrophy (DMD) has been submitted to the European Medicine Agency (EMA) and that the EMA has started its regulatory review process.
  • The MAA submission to the EMA follows Italfarmaco Group's New Drug Application (NDA) submission for Givinostat to the U.S. Food and Drug Administration (FDA), which has granted priority review for Givinostat as announced in June this year .
  • “The Phase 3 evaluation of Givinostat demonstrated that it can slow DMD progression in boys six years and older.
  • If approved, Givinostat could greatly benefit younger and older DMD patients by preserving their motor skills and muscle strength,” said Paolo Bettica, MD, PhD, Chief Medical Officer at Italfarmaco Group.

Stress Affects Sex. Male Plus Can Help.

Retrieved on: 
Wednesday, August 30, 2023

Fort Lauderdale, FL, Aug. 30, 2023 (GLOBE NEWSWIRE) -- Male Plus is a natural libido-enhancing brand that has recently entered the U.S. marketplace.

Key Points: 
  • Fort Lauderdale, FL, Aug. 30, 2023 (GLOBE NEWSWIRE) -- Male Plus is a natural libido-enhancing brand that has recently entered the U.S. marketplace.
  • It can derail your focus and undermine your emotional state.”
    Torfs clarifies that stress is a major factor in life.
  • However, high levels of stress or chronic stress can negatively impact the body.
  • With ginseng in the mix, Male Plus becomes not just a libido enhancer but a destressing agent.

Hua Medicine Announces 2023 Interim Results

Retrieved on: 
Friday, August 25, 2023

Hua Medicine (the "Company", HKEx: 2552) today announces the unaudited consolidated results of the Company and its subsidiaries for the six months ended June 30, 2023 (the "Reporting Period").

Key Points: 
  • Hua Medicine (the "Company", HKEx: 2552) today announces the unaudited consolidated results of the Company and its subsidiaries for the six months ended June 30, 2023 (the "Reporting Period").
  • Dr. Li Chen, the founder and CEO of Hua Medicine, said, "the first half of 2023 was a critical stage for Hua Medicine to begin commercialization.
  • The revenue of Hua Medicine for the first half of 2023 was RMB70.3 million, which was an increase of approximately 299.6% comparing to the second half of 2022.
  • This article contains the statements regarding the future expectations, plans and prospects for Hua Medicine and the investigational product.

Kanazawa University research: Researchers define a nanopipette fabrication protocol for high resolution cell imaging

Retrieved on: 
Tuesday, August 22, 2023

KANAZAWA, Japan, Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.

Key Points: 
  • KANAZAWA, Japan, Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.
  • Now researchers led by Yasufumi Takahashi at Kanazawa University's Nano LSI and Nagoya University have devised a protocol for reproducibly fabricating nanopipettes with the preferred geometry for high quality imaging.
  • Scanning ion conductance microscopy (SICM) uses a nanopipette to control the nanopipette-samples distance using an ion current as feedback signal.
  • Nanopipette Fabrication Guidelines for SICM Nanoscale Imaging, Analytical Chemistry August 20, 2023.

Kanazawa University research: Researchers define a nanopipette fabrication protocol for high resolution cell imaging

Retrieved on: 
Tuesday, August 22, 2023

KANAZAWA, Japan , Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.

Key Points: 
  • KANAZAWA, Japan , Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.
  • Now researchers led by Yasufumi Takahashi at Kanazawa University's Nano LSI and Nagoya University have devised a protocol for reproducibly fabricating nanopipettes with the preferred geometry for high quality imaging.
  • Scanning ion conductance microscopy (SICM) uses a nanopipette to control the nanopipette-samples distance using an ion current as feedback signal.
  • Nanopipette Fabrication Guidelines for SICM Nanoscale Imaging, Analytical Chemistry August 20, 2023.

Specialdocs Launches 10 Personalized Care Practices Nationwide Since the Start of 2023

Retrieved on: 
Tuesday, July 18, 2023

“Like concierge medicine itself, which allows for deeply personalized doctor-patient relationships, our model is grounded in a trusted and enduring partnership.

Key Points: 
  • “Like concierge medicine itself, which allows for deeply personalized doctor-patient relationships, our model is grounded in a trusted and enduring partnership.
  • It’s like night and day in terms of how I can care for and really know my patients.
  • We signed up for her personalized medical care as soon as she made it available.
  • I told her then ‘I’d been hoping for years you would start a practice like this.