LBM

EQS-News: beaconsmind Group gains rapidly growing student dormitory operator as a new customer

Retrieved on: 
Wednesday, March 13, 2024
LBM, Ticker, Software as a service, WLAN, VPN

beaconsmind Group has developed a VPN concept with camera surveillance for all 10 locations of the company in Germany and Austria, comprising a total of over 3,000 apartments.

Key Points: 
  • beaconsmind Group has developed a VPN concept with camera surveillance for all 10 locations of the company in Germany and Austria, comprising a total of over 3,000 apartments.
  • In the medium term, beaconsmind Group plans to expand its activities into areas such as WLAN infrastructure.
  • This customer project generates a revenue of approximately EUR 0.5 million for beaconsmind Group.
  • The contract signing presents attractive growth opportunities for beaconsmind Group."

EQS-News: beaconsmind Group has delivered and installed new projection technology for the stage at the Semperoper Dresden, one of Germany's largest opera houses

Retrieved on: 
Wednesday, March 13, 2024
Analytics, LBM, EUR, Software as a service, TSD, Music

beaconsmind Group has delivered and installed new projection technology for the stage at the Semperoper Dresden, one of Germany's largest opera houses

Key Points: 
  • beaconsmind Group has delivered and installed new projection technology for the stage at the Semperoper Dresden, one of Germany's largest opera houses
    The issuer is solely responsible for the content of this announcement.
  • beaconsmind Group has delivered and installed new projection technology for the stage at the Semperoper Dresden, one of Germany's largest opera houses
    The customer project is associated with a revenue of 200 TSD.
  • The use of projection technology enables more stage areas to be illuminated than ever before while simultaneously reducing the need for physical set construction.
  • The contract conclusion has generated a total revenue volume of approximately 200 thousand euros for the beaconsmind Group.

EQS-News: beaconsmind-solution enables significant improvement in customer ratings for a salon business Ryf with around 100 locations in Germany and Switzerland

Retrieved on: 
Wednesday, March 13, 2024
Marketing, Analytics, LBM, Software as a service, Partnership

This success was made possible through collaboration with Socialwave GmbH, a subsidiary of beaconsmind Group in Munich.

Key Points: 
  • This success was made possible through collaboration with Socialwave GmbH, a subsidiary of beaconsmind Group in Munich.
  • The average rating of the participating salons increased from 4.4 to 4.7 stars, while the number of ratings doubled.
  • This success story underscores Ryf's commitment to excellence and customer satisfaction as well as the effectiveness of the innovative solutions from the beaconsmind Group.
  • Jonathan Sauppe, CEO of beaconsmind Group: "We are proud to have supported Ryf in significantly increasing their online presence and customer ratings.

EQS-News: beaconsmind Group: The retail company Müller deploys innovative WLAN solutions by beaconsmind group across its European stores

Retrieved on: 
Wednesday, March 13, 2024
Multimedia, DACH, LBM, Internet access, Customer, Software as a service, AG, Wi-Fi, Internet service provider

Müller Holding GmbH & Co. KG is present in eight countries across Europe with over 900 stores.

Key Points: 
  • Müller Holding GmbH & Co. KG is present in eight countries across Europe with over 900 stores.
  • The company was closely involved in installing the solution in all markets and, as an internet provider, ensures network stability and security in Müller stores.
  • Müller's IT, swissnet, and the beaconsmind Group equipped Müller's stores with customer Wi-Fi within just six months through close collaboration.
  • Felix Leupert, VP Sales of beaconsmind AG, stated: "We are very pleased to have gained another traditional retail company like Müller as a long-term customer for our solution.

Reflection paper on investigation of pharmacokinetics in the obese population - Scientific guideline

Retrieved on: 
Wednesday, February 14, 2024
Leptin, PD, Metabolism, Toxicity, Body composition, Ciprofloxacin, Clinical Pharmacokinetics, Water, LBW, Perfusion, LBM, Canadian International Council, AUC, PLOS One, Bariatric surgery, Clopidogrel, CYP, Breast, Health, DNA-binding protein, BMC Public Health, Pharmacology, BMI, CRP, Pharmaceutical Research (journal), Organ, Draft, Guideline, Bypass surgery, WHO, Ageing, INT, Pharmacokinetics, Liver, Bioavailability, Chronic liver disease, Human, Incidence, Committee, Absorption, TBW, Cardiovascular disease, Anatomy, CYP2C19, PBPK, Cmax, Factorization of polynomials, European, Lancet, CHMP, Journal, NASH, Pharmacotherapy, Adipose tissue, Non-alcoholic fatty liver disease, Journal of Clinical Investigation, Medication package insert, Overweight, NPS MedicineWise, Permeability, Benzodiazepine, Meta-analysis, Liver disease, Half-life, Acetylcholine, Ciclosporin, AAG, Kinetics, Midazolam, Kidney, Safety, Biomarker, Clinical Pharmacology & Therapeutics, Peptide, Classification, Hypertension, Metabolic syndrome, Acute coronary syndrome, Insulin resistance, Fatty liver disease, CYP2E1, Lithium, Body mass index, Reproduction, EMA, IBW, Injection, Anker, NCA, Enzyme, Inflammation, Cancer, Weight loss, Gastrointestinal tract, Cardiac output, Public health, Adipokine, CYP2C9, E pluribus unum, Physiology, Agency, Risk, Steroid, Lymph, CYP2D6, BSA, GI, Cytokine, Systematic review, Vaccine

Reflection paper on investigations of pharmacokinetics in

Key Points: 
    • Reflection paper on investigations of pharmacokinetics in
      the obese population
      Table of contents
      1.
    • References .............................................................................................. 9

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 2/12

      1.

    • This is considered
      a shortcoming that is potentially compounded by obese patients often being poorly represented in
      clinical studies.
    • The specific aims of this reflection paper are to:
      ?

      describe how the effects of obesity can be investigated during clinical medicinal product
      development.

    • ?

      provide recommendations on when investigations of the effect of obesity on the PK of a
      medicinal product should be particularly considered.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 3/12

      ?

      discuss how to reflect PK (and/or PK/PD) findings in weight/weight-based dosing
      recommendations.

    • Absorption
      Reduced rate of absorption linked to locally reduced blood flow (8) is reported for the subcutaneous
      and transdermal routes in obese subjects.
    • Distribution
      The distribution of medicinal products is driven by body composition, regional blood flow and binding to
      tissue and plasma proteins.
    • Obese subjects have a larger absolute lean body weight (LBW) as well as fat mass.
    • The physicochemical properties of a medicinal product (lipophilicity, polarity, molecular size, and
      degree of ionization) influence its distribution in the body.
    • In BMI class III obese
      subjects, the blood flow per gram of fat is significantly lower than that observed in class I obese or
      lean subjects (4).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 4/12

      An increased amount of alpha-1-acid-glycoprotein (AAG), linked to a chronic inflammatory state, is
      reported in obese individuals.

    • Fatty infiltrations are present in the liver for 90% of obese subjects, with the extent of the infiltrations
      being proportional to the degree of obesity.
    • In some cases, in particular for CYP3A4 metabolized medicinal products,
      bodyweight normalized clearance can be lower in obese patients (23).
    • Based on presently available data, it has been suggested that uptake transporters

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 5/12

      are downregulated while efflux transporters may be upregulated (31).

    • Platelet hyper-reactivity is also observed,
      which can impair the response to anti-platelet medicinal products in obese patients (42, 43).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 6/12

      3.

      the medicinal product properties and scientific literature indicate that obesity may lead to a
      marked effect on elimination and/or distribution or on the PK/PD relationship.

    • These
      models may aid in extrapolating the known efficacy and safety in the non-obese population to the
      obese population.
    • The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients
      Before and One Year After Bariatric Surgery.
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 11/12

      41.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 12/12

ECI Software Solutions to Share Expert Insights on Ecommerce Integration for Lumber and Building Materials (LBM) Businesses at the True Value Spring Reunion

Retrieved on: 
Tuesday, January 30, 2024
LBM, ECI, Online shopping

FORT WORTH, Texas, Jan. 30, 2024 /PRNewswire-PRWeb/ --

Key Points: 
  • The event aims to promote collaboration among businesses through a series of presentations, activities, demonstrations and more.
  • ECI Software Solutions , a global provider of cloud-based business management software and services, will share expert insights, go-forward strategies and pitfalls to avoid when integrating ecommerce solutions.
  • Tailored for small- and medium-sized LBM and hardlines distributors, the ecommerce presentation will take place during the True Value Reunion February 1-4, 2024 in New Orleans.
  • To learn more about the True Value 2024 Spring Reunion, visit the event website .

EQS-News: beaconsmind Group is supporting one of the largest nursing home operators in Germany in furthering their digitalization process

Retrieved on: 
Tuesday, January 30, 2024
Housing, Software as a service, Documentation, Computer, Ticker, Caregiver, EUR, Tablet, Telephone, Nursing, Television, LBM, Internet service provider

The company is expanding its existing collaboration with Vitanas Group ("Vitanas"), one of the largest private nursing home operators in Germany.

Key Points: 
  • The company is expanding its existing collaboration with Vitanas Group ("Vitanas"), one of the largest private nursing home operators in Germany.
  • The beaconsmind Group is implementing its cloud solution FREDERIX CloudWiFi for comprehensive Wi-Fi coverage at 15 Vitanas locations with a total of around 2,500 nursing care places.
  • Using existing telephone and television cabling as a computer network, beaconsmind Group's Wi-Fi solutions help reduce installation effort and costs significantly.
  • Jonathan Sauppe, CEO of beaconsmind, commented: "The new deal presents exciting growth opportunities for beaconsmind Group.

EQS-News: beaconsmind AG presents new Smart Urban Lightning Eco System at upcoming trade fairs

Retrieved on: 
Wednesday, January 17, 2024
Light, Lighting, Intersec, Heart, City, Software as a service, Wi-Fi, Sale, Exhibition, Ticker, Axis Communications, Safety, LBM, Smart, Internet of things

The exhibition will focus on the Smart Urban Lighting Eco System, a holistic solution for smart cities and urban environments developed by beaconsmind, WE-EF Leuchten GmbH, which is active in the field of outdoor lighting technology, and Axis Communications AB, the industry leader in video security.

Key Points: 
  • The exhibition will focus on the Smart Urban Lighting Eco System, a holistic solution for smart cities and urban environments developed by beaconsmind, WE-EF Leuchten GmbH, which is active in the field of outdoor lighting technology, and Axis Communications AB, the industry leader in video security.
  • At the heart of this system is the Smart Lighting Pole, an intelligent lighting pole with numerous functions and tools that can be adapted to the individual needs of cities, municipalities and private companies.
  • The beaconsmind Suite software is also integrated into the Smart Lighting Pole.
  • beaconsmind offers operators of the Smart Lighting Pole all managed services relating to the pole from a single source on request.

Virta Expands its Provider-led Weight Loss Program to Adults with BMI >25 As Demand Surges for Cost Effective Alternatives to GLP-1 Drugs

Retrieved on: 
Thursday, January 4, 2024
Diabetes, Health, Fitness & Nutrition, Well, Patient, Blue Shield, Semaglutide, Overweight, Weight loss, AutoZone, BMI, Conditional sentence, LBM, Pilot Flying J, Name, Metabolic disorder, Obesity, Type 2 diabetes, Traction, U-Haul, Prediabetes, Magic, Growth, Life, Pharmaceutical industry

Virta Health, the leader in drug-free clinical weight loss and type 2 diabetes reversal, today announced significant traction against the company’s expansion into weight loss solutions.

Key Points: 
  • Virta Health, the leader in drug-free clinical weight loss and type 2 diabetes reversal, today announced significant traction against the company’s expansion into weight loss solutions.
  • “Virta delivers drug-like impact, without the drugs,” said Dr. Adam Wolfberg, Chief Medical Officer at Virta.
  • For nearly a decade, Virta Health has been de-prescribing GLP-1 drugs while sustaining clinically significant weight loss.
  • Because much of the weight loss is regained once people stop using the drugs, much of the spend on GLP-1s is also therefore wasted.

Dotmatics Acquires M-Star to Expand Presence in Bioprocessing and Chemicals & Materials Markets

Retrieved on: 
Thursday, January 4, 2024
Conference, Software, Research, Acquisition, Mechanical engineering, LBM, MBA, Doctor of Philosophy, Carnegie Mellon University, GPU, BVH, Growth, CFD, Mechanical, Acceleration, Algorithm, Environment, Online shopping

BOSTON, Jan. 4, 2024 /PRNewswire/ -- Dotmatics, a leader in R&D scientific software connecting science, data, and decision-making, today announced the acquisition of M-Star, a leading computational fluid dynamics (CFD) software company headquartered outside of Baltimore, Maryland. The deal marks the 13th acquisition by Dotmatics expanding its comprehensive, multimodal platform for life sciences research & development and extending its product capabilities in chemicals and materials sciences. The addition of M-Star provides additional opportunities for innovation in the bioprocessing market including the manufacturing of cell and gene therapies in life sciences R&D.

Key Points: 
  • The deal marks the 13th acquisition by Dotmatics expanding its comprehensive, multimodal platform for life sciences research & development and extending its product capabilities in chemicals and materials sciences.
  • The addition of M-Star provides additional opportunities for innovation in the bioprocessing market including the manufacturing of cell and gene therapies in life sciences R&D.
  • "M-Star is known for its differentiated CFD analysis product, featuring accelerated analysis capabilities, superior user experiences, and rapid time-to-value compared to other market solutions," said Thomas Swalla, CEO of Dotmatics.
  • To schedule a meeting with Dotmatics executives and corporate development team, please contact [email protected] .