Attention deficit hyperactivity disorder

You might have heard ADHD risks being over-diagnosed. Here's why that's not the case

Retrieved on: 
Wednesday, June 28, 2023

One hot topic is whether ADHD is being over-diagnosed.

Key Points: 
  • One hot topic is whether ADHD is being over-diagnosed.
  • Public hearings for the Australian Senate’s inquiry into “consistent, timely and best practice assessment” of ADHD and support services begin today.

What is ADHD?

    • Worldwide, around 5% of children and 2.5% of adults meet the full diagnostic criteria for ADHD.
    • Importantly, just having hyperactive, impulsive and inattentive symptoms is not sufficient to qualify for a diagnosis of ADHD.
    • To meet current diagnostic criteria, these symptoms must have a negative effect on a person’s “social, school, or work functioning”.

Overdiagnosis or misdiagnosis?

    • Overdiagnosis is a concept first developed in cancer screening to highlight situations where “the diagnosis of disease that would never cause symptoms or death during a given patient’s lifetime”.
    • This definition has since been employed in many other areas of medicine, as well as analyses of health systems.
    • When defined in this way, overdiagnosis is distinct from the concept of misdiagnosis, which is where an incorrect diagnosis has been made.

Different definitions

    • One 2021 article on ADHD and overdiagnosis defined it as occurring when the “net effect of the diagnosis is unfavourable”.
    • There are many reasons an ADHD diagnosis may be “unfavourable”, for some individuals.
    • Some people experience negative side effects from ADHD treatments, or experience stigma as a result of ADHD diagnosis.
    • But when you think about ADHD as not just having certain symptoms, but as having harmful outcomes, this might be expected.

Not a medical condition

    • Some concerns about ADHD overdiagnosis appear to be based on a belief ADHD should not be considered as a medical condition.
    • From this perspective, the concerns would again be more accurately and transparently phrased in terms of misdiagnosis.
    • Even in the United States where rates of ADHD diagnosis exceed 5%, they still fall short of the estimated epidemiological prevalence.

Where to from here?

    • So GPs and others – like Mental Health Nurse Practitioners – may well play an important role in assessing and managing ADHD.
    • There would clearly need to be extensive training and support and also changes in the way assessments are funded.
    • He also receives funding from the Medical Research Future Fund David Coghill receives funding from The National Health & Medical Research Council and the Medical Research Future Fund.

Journal Frontiers in Psychiatry Publishes Analysis of Open Label Safety Study Showing Improvements in Sleep Habits for Children With ADHD After Treatment With AZSTARYS® (serdexmethylphenidate and dexmethylphenidate)

Retrieved on: 
Monday, June 26, 2023

BOSTON, June 26, 2023 /PRNewswire/ -- Corium, LLC, a commercial-stage biopharmaceutical company leading the development and commercialization of novel central nervous system (CNS) therapies, announced today that the peer-reviewed journal Frontiers in Psychiatry published an analysis of a yearlong open-label safety study of Corium's attention-deficit hyperactivity disorder (ADHD) medicine AZSTARYS (serdexmethylphenidate [SDX] and dexmethylphenidate [d-MPH]). AZSTARYS was approved by the U.S. Food and Drug Administration in 2021 for the treatment of ADHD symptoms in people aged 6 years through adulthood. The analysis showed that study participants, children aged 6 to 12 years with ADHD and treated with AZSTARYS for up to twelve months, had statistically significant and lasting improvements in their sleep as assessed by the Children's Sleep Habits Questionnaire (CSHQ), a caregiver-reported screening survey designed to assess behavioral and medically based sleep problems in school children.

Key Points: 
  • AZSTARYS was approved by the U.S. Food and Drug Administration in 2021 for the treatment of ADHD symptoms in people aged 6 years through adulthood.
  • Almost three in four children with ADHD have some sleep impairment, according to Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), a national nonprofit organization serving people affected by ADHD.
  • After one month of AZSTARYS treatment, the children's average CSHQ total sleep disturbance score significantly decreased, indicating improved sleep.
  • Moreover, after 12 months of treatment their average CSHQ total score remained in the 48.9 to 50.1 range, indicating the children sustained overall sleep improvements while receiving AZSTARYS.

Making pride more inclusive means creating space for 2SLGBTQ+ people with disabilities

Retrieved on: 
Sunday, June 25, 2023

Although 2SLGBTQ+ people are becoming more accepted, those living with disabilities still struggle to be seen and heard.

Key Points: 
  • Although 2SLGBTQ+ people are becoming more accepted, those living with disabilities still struggle to be seen and heard.
  • For instance, in one study from the United States, LGBTQ+ autistic people reported:
    feeling “othered,” discredited [and] tolerated rather than accepted.
  • As a consequence, some disabled people choose to avoid disclosing their disability in queer spaces to avoid negative responses and rejection.

Feeling like outsiders in their own communities

    • Some disabled people reported feeling like outsiders in queer spaces and communities.
    • As a participant noted: “I didn’t really want to participate in queer spaces because I felt like an interloper.
    • In another study with autistic adults, participants talked about how both the disabled and queer communities can sometimes ostracize autistic people rather than being “open-minded” and “accepting” spaces.
    • For those who are disabled and queer, being left out of 2SLGBTQ+ spaces means they do not receive the benefits of feeling like they belong.

Making queer spaces more accessible

    • Participants from various studies have shared suggestions for making queer spaces more accessible.
    • They do not wish to have to fight for the right to exist in queer spaces safely.
    • 2SLGBTQ+ spaces should inherently be where people can learn more about different identities and build communities, not spaces of exclusion.
    • Disabled people should be meaningfully invited into queer spaces.

Hopper Health Names Former Brightline Executive Jonathan Simon Co-Founder and Chief Technology Officer

Retrieved on: 
Tuesday, June 20, 2023

His appointment at Hopper Health signifies the company's commitment to innovation and advancing healthcare accessibility for neurodivergent communities.

Key Points: 
  • His appointment at Hopper Health signifies the company's commitment to innovation and advancing healthcare accessibility for neurodivergent communities.
  • As CTO, Jonathan will spearhead Hopper's technology strategy, playing a pivotal role in enhancing the company's digital infrastructure, expanding its offerings, acquiring new patients, and building out the technology team.
  • "We are delighted to welcome Jonathan Simon to Hopper as our new Chief Technology Officer and my co-founder.
  • Prior to his role at Brightline, Simon served in technology leadership positions at companies including Meta, AllTrails, and Qualcomm.

TELUS Health 2023 Drug Trends Report: Diabetes now the top drug category for claims; antidepressants surged for youth

Retrieved on: 
Tuesday, June 13, 2023

TORONTO, June 13, 2023 (GLOBE NEWSWIRE) -- Today, TELUS Health issued its annual 2023 Drug Data Trends and National Benchmarks Report , revealing that diabetes has replaced inflammatory diseases, such as rheumatoid arthritis, as the top drug category for claims in Canada.

Key Points: 
  • TORONTO, June 13, 2023 (GLOBE NEWSWIRE) -- Today, TELUS Health issued its annual 2023 Drug Data Trends and National Benchmarks Report , revealing that diabetes has replaced inflammatory diseases, such as rheumatoid arthritis, as the top drug category for claims in Canada.
  • “It is our hope that the findings in our 2023 Drug Trends Report will continue to offer private payors and benefits advisors valuable insights to help adjust and improve benefits plans,” said Martin Bélanger, Managing Director, Payor Solutions, TELUS Health.
  • “The fact that growth in spend has been observed in a specific diabetes class of drugs suggests that existing claimants are switching to more costly therapies,” noted Lavina Viegas, Pharmacist, TELUS Health.
  • Published annually since 2015, the TELUS Health Drug Data Trends and National Benchmarks Report is based on the claims data of the 2022 TELUS Health portfolio, and provides a contextual view of adoption rates of plan management trends to help insurers and employers alike understand major trends in prescription drug utilization.

PADAGIS ANNOUNCES TWO PRODUCT LAUNCHES

Retrieved on: 
Friday, June 9, 2023

Tazorac® Gel 0.1% is also indicated for the topical treatment of patients with facial acne vulgaris of mild to moderate severity.

Key Points: 
  • Tazorac® Gel 0.1% is also indicated for the topical treatment of patients with facial acne vulgaris of mild to moderate severity.
  • Annual market sales for Tazorac® Gel were approximately $11 million in the 12 months ended April 2023 as measured by IQVIA.
  • Padagis President, Pam Hoffman, stated, "Padagis enters as the second generic prescription product to launch in each of these markets, demonstrating our ability to select and execute on pipeline products that bring value to our customers and patients alike.
  • Many thanks to the development, regulatory, supply chain and commercial teams at Padagis for their work on these important launches."

ADHD: inattention and hyperactivity have been the focus of research – but emotional problems may be the missing link

Retrieved on: 
Saturday, June 10, 2023

ADHD is diagnosed using criteria from a document called DSM-5, which include symptoms of inattention, hyperactivity and impulsivity.

Key Points: 
  • ADHD is diagnosed using criteria from a document called DSM-5, which include symptoms of inattention, hyperactivity and impulsivity.
  • But it is becoming increasingly clear to researchers that the condition also comes with self-control problems, affecting the ability to regulate emotions.
  • For example, 2.1% of children with a diagnosis of ADHD also have a mood disorder, such as depression, while 27.4% have an anxiety disorder.
  • Children with anxiety and depression symptoms only exhibited those deficits if they also had problems with attention.
  • So it seems that one possible route to helping children with ADHD or mood disorders with cognitive development is to focus on improving their attention.

Treatments

    • Methylphenidate roughly works by increasing three chemicals in the brain: dopamine, serotonin and noradrenaline.
    • Dopamine can improve attention, learning, working memory and motivation, while noradrenaline reduces impulsivity and boosts attention.
    • This research suggests that cognitive control, which is associated with frontal areas, can be improved by methylphenidate.
    • This should be offered to children with ADHD, in conjunction with pharmacological treatments.

ADHD on the rise

    • The number of ADHD diagnoses are rising across the world, and so are prescriptions of methylphenidate.
    • In the UK, a study estimated that the use of ADHD medications has increased by almost 800% from 2000 to 2015.
    • It may be that the prevalence of ADHD will increase even more in the future as coping strategies become less effective and people seek help and ultimately receive a diagnosis.
    • The more we learn about brain basis of ADHD, the easier it will get to treat.

ChildCare Education Institute Offers No-Cost Online Course on Attention Deficit Hyperactivity Disorder

Retrieved on: 
Thursday, June 1, 2023

ATLANTA, GA, June 01, 2023 (GLOBE NEWSWIRE) -- ChildCare Education Institute® (CCEI), one of the largest online training providers dedicated exclusively to the early care and education workforce, offers SPN107: Attention Deficit Hyperactivity Disorder as a no-cost trial course to new CCEI users June 1-30, 2023.

Key Points: 
  • ATLANTA, GA, June 01, 2023 (GLOBE NEWSWIRE) -- ChildCare Education Institute® (CCEI), one of the largest online training providers dedicated exclusively to the early care and education workforce, offers SPN107: Attention Deficit Hyperactivity Disorder as a no-cost trial course to new CCEI users June 1-30, 2023.
  • For a child care provider, the effects of Attention Deficit Hyperactivity Disorder (ADHD) in the classroom can be quite obvious.
  • This course presents basic facts about Attention Deficit Hyperactivity Disorder (ADHD), including characteristics of children diagnosed with ADHD, recommended classroom accommodations, and strategies to support adults with ADHD.
  • “Early childhood professionals must implement strategies and apply specialized knowledge to meet all children's individual needs.”
    SPN107: Attention Deficit Hyperactivity Disorder is a two-hour, beginner-level course and grants 0.2 IACET CEU upon successful completion.

Qbtech, Inc. Issues Commentary In Support of DEA’s Extension of Temporary Rule for Telehealth Treatment

Retrieved on: 
Tuesday, May 23, 2023

Qbtech , Inc., a leading advocate on a mission to improve mental health outcomes, shares its full support for the extension of the Drug Enforcement Administration's (DEA) temporary rule through November 11, 2023.

Key Points: 
  • Qbtech , Inc., a leading advocate on a mission to improve mental health outcomes, shares its full support for the extension of the Drug Enforcement Administration's (DEA) temporary rule through November 11, 2023.
  • “The adoption of measurement-based care in behavioral health, already the standard in England, is gaining traction in the U.S., including through telehealth models.
  • “We maintain a hopeful outlook as the extension of the temporary rule potentially signifies a meaningful step toward addressing these concerns,” adds Letterle.
  • To show your support, you can add your signature to the ADHD Expert Consortium’s Consensus Statement , which calls for the standardization of care.

Myriad Genetics Reports First Quarter 2023 Financial Results; Achieves 10% Revenue Growth Year-Over-Year, the Second Consecutive Quarter of Double-Digit Year-Over-Year Revenue Growth; Raises Mid-Point of 2023 Revenue Guidance Range

Retrieved on: 
Wednesday, May 3, 2023

SALT LAKE CITY, May 03, 2023 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc. (NASDAQ: MYGN), a leader in genetic testing and precision medicine, today announced financial results for its first quarter ended March 31, 2023. The company also updated its 2023 financial guidance and provided an update on business performance.

Key Points: 
  • GAAP total operating expenses in the first quarter of 2023 were $174.2 million, decreasing $31.7 million year-over-year.
  • Ended the first quarter of 2023 with $109.1 million in cash, cash equivalents and marketable investment securities.
  • The Myriad Genetics Oncology business provides hereditary cancer testing, including the MyRisk® hereditary cancer test for patients who have cancer.
  • ET to discuss Myriad Genetics’ financial results and business developments for the first quarter 2023.