Insemination

African wild dogs will soon have their own sperm bank – how artificial breeding will help them survive

Retrieved on:

Wednesday, April 10, 2024

Lion, Gene, Disease, Lycaon, Rabies, Livestock, Research, Female, University, Freezing, Male, Dog, Breeding, Animal, Insemination, Hunting

They’ve now decided to freeze sperm from as many genetically diverse male African wild dogs as possible and use this to artificially inseminate female African wild dogs for the first time.

Key Points:

They’ve now decided to freeze sperm from as many genetically diverse male African wild dogs as possible and use this to artificially inseminate female African wild dogs for the first time.
Reproductive and molecular biologist Damien Paris explains why artificial breeding is the best and most economical way to ensure that genetically diverse wild dogs live on.

Why is the African wild dog in danger?

They are highly efficient pack hunters but need large home ranges to survive and avoid competitors like lions.
The problem is that most of the remaining habitats are so small and fragmented that they can’t support large populations anymore.
Usually, when wild dogs are subadults (around two years old) they move far away and form their own pack.

How can genetic diversity help the African wild dog survive?

Those diseases can spread rapidly among wild dogs and decimate a pack, which is about five to 20 dogs.
In 2017, canine distemper virus completely wiped out 21 out of 22 packs of wild dogs in Laikipia County, Kenya in less than four weeks.
We plan to use sperm freezing and artificial insemination to help distribute genetic diversity between isolated populations.

What conservation methods have been used before?

To increase genetic diversity, African wild dogs have been translocated (moved) across South Africa since 1998.
Over several weeks, they form a new genetically mixed pack that is released into the wild.
A whole population of wild dogs could be lost with the next disease outbreak.

How will sperm freezing and artificial insemination help?

Our back-up plan against disease outbreaks is to create a bank of African wild dog sperm from multiple males.
Sperm frozen in liquid nitrogen tanks at very cold temperatures can last 50 or 100 years and still produce offspring.
We recently improved the freezing technique so African wild dog sperm are now able to swim and survive for eight hours after being thawed.
We plan to build a consortium so that we can have multiple sperm banks throughout South Africa as back-ups.

Will this be very expensive?

Some recent modelling in other species found that the hybrid approach was between seven and 84 times cheaper than the natural breeding approach.
This is because it needed 13-100 times fewer animals to maintain 90% genetic diversity in the population over a 100-year period.

Damien Boyd Bertrand Paul Paris receives funding from Morris Animal Foundation, Roger Willliams Park
Zoo and Fresno Chaffee Zoo. He is affiliated with James Cook University, the Institute for Breeding Rare and Endangered African Mammals, and is a Visiting Fellow of the Mammal Research Institute.

Femasys Announces Financial Results for Year Ended December 31, 2023 and Provides Corporate Update

Retrieved on:

Thursday, March 28, 2024

Woman, Male, FDA, Infertility, Insemination, Pharmaceutical industry

ATLANTA, March 28, 2024 (GLOBE NEWSWIRE) -- Femasys Inc. (NASDAQ: FEMY), a leading biomedical company focused on addressing significant unmet needs of women worldwide with a broad portfolio of in-office, accessible and innovative therapeutic and diagnostic products, announces financial results for the year ended December 31, 2023 and provides a corporate update.

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ATLANTA, March 28, 2024 (GLOBE NEWSWIRE) -- Femasys Inc. (NASDAQ: FEMY), a leading biomedical company focused on addressing significant unmet needs of women worldwide with a broad portfolio of in-office, accessible and innovative therapeutic and diagnostic products, announces financial results for the year ended December 31, 2023 and provides a corporate update.
Following FDA clearance of FemaSeed, the Company’s revolutionary approach to artificial insemination, Femasys announced completion of enrollment in pivotal trial in support of commercial launch
Appointed Richard Spector as Chief Commercial Officer and James Liu, M.D.
Notably, the majority of women who became pregnant did so after the first FemaSeed procedure,” said Femasys’ CEO Kathy Lee-Sepsick.
“Our focus is now on executing on commercialization of FemaSeed and our other available products, as well as advancing the clinical pivotal trial for FemBloc.

Femasys Announces Positive Topline Data from Pivotal Trial for its FDA-Cleared FemaSeed® for the Treatment of Infertility

Retrieved on:

Wednesday, March 20, 2024

Infertility, TMSC, Pregnancy rate, IVF, IUI, Pregnancy, Fertilisation, Woman, Male, Safety, Literature, FDA, ICSI, Insemination, Physician, Birth control

ATLANTA, March 20, 2024 (GLOBE NEWSWIRE) -- Femasys Inc. (NASDAQ: FEMY), a leading biomedical company focused on addressing significant unmet needs of women worldwide with a broad portfolio of in-office, accessible, and innovative therapeutic and diagnostic products, today announces topline data from its FemaSeed Localized Directional Insemination for artificial insemination pivotal trial (NCT04968847). The trial investigated its FemaSeed product in women with a variety of infertility factors with the primary efficacy analysis focused on the severe male factor infertility. FemaSeed, engineered to enhance fertilization by precisely delivering sperm into the fallopian tube, the site of conception, demonstrated 24% of women became pregnant after FemaSeed with severe male factor (1 million to 20 million total motile sperm count (TMSC)). In contrast, a 6.7% pregnancy rate by cycle was described in the literature for intrauterine insemination (IUI) with male factor (greater than 1 million TMSC).1 Although permitted to have multiple FemaSeed attempts, the majority of women who became pregnant did so after the first FemaSeed procedure. The poor IUI pregnancy rates for this infertility segment usually necessitates assisted reproductive approaches, such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

Key Points:

The trial investigated its FemaSeed product in women with a variety of infertility factors with the primary efficacy analysis focused on the severe male factor infertility.
“These impressive topline results for our now FDA-cleared FemaSeed, demonstrate significant progress in the treatment of infertility, while confirming its safety profile.
“The pivotal trial amassed substantial prospective data in support of the safety and efficacy of FemaSeed as a groundbreaking advancement in artificial insemination.
The pivotal trial was concluded prior to completing full enrollment due to Femasys receiving FDA clearance for FemaSeed under the 510(k) pathway in September 2023.

San Diego Zoo Wildlife Alliance and China Wildlife Conservation Association Sign a New Cooperative Agreement for Giant Panda Collaboration

Retrieved on:

Thursday, February 22, 2024

SAN, Intake, Insemination, Genetics, San Diego Zoo, Physiology, Conservation science, Health, Climate change, GPS, Reproduction, Survival, Science, Partnership

SAN DIEGO, Feb. 22, 2024 /PRNewswire/ -- San Diego Zoo Wildlife Alliance (SDZWA) took an important step forward in having giant pandas return to the San Diego Zoo by signing a cooperative agreement with China Wildlife Conservation Association and filing a permit application with the U.S. Fish and Wildlife Service.

Key Points:

SAN DIEGO, Feb. 22, 2024 /PRNewswire/ -- San Diego Zoo Wildlife Alliance (SDZWA) took an important step forward in having giant pandas return to the San Diego Zoo by signing a cooperative agreement with China Wildlife Conservation Association and filing a permit application with the U.S.
SDZWA has a nearly 30-year conservation partnership with research collaborators in China focused on protecting and recovering giant pandas.
As such, San Diego Zoo Wildlife Alliance is taking important steps to ensure we are prepared for a potential return.
San Diego Zoo Wildlife Alliance is uniquely positioned to collaborate toward a shared goal of creating a sustainable future for giant pandas."

PherDal, the First and Only Sterile At-Home Insemination Kit, Awarded FDA Clearance; Now Accepting Pre-Orders

Retrieved on:

Tuesday, January 16, 2024

Fertility, Infertility, Science, Insemination, LSI, Kit, Genomics, Conference, IVI, Femtech, FDA

DIXON, Ill., Jan. 16, 2024 /PRNewswire-PRWeb/ -- PherDal Fertility Science, Inc., creators of the first and only sterile, at-home insemination kit, is now accepting pre-orders of its intravaginal insemination (IVI) device, following FDA class II clearance. Rooted in science, the PherDal Kit is the first and only to combine the sterile environment of the fertility clinic with the at-home capabilities of insemination.

Key Points:

Rooted in science, the PherDal Kit is the first and only to combine the sterile environment of the fertility clinic with the at-home capabilities of insemination.
Rooted in science, the PherDal Kit is the first and only to combine the sterile environment of the fertility clinic with the at-home capabilities of insemination.
Each PherDal Kit includes three (3) sterile syringes and three (3) sterile collection cups to make at-home insemination as sterile, safe and accessible as possible.
My husband, a mechanical engineer, and I invented the PherDal Kit, which successfully conceived our daughter with the second use.

Femasys Inc. Announces the Appointment of James Liu, M.D., as Chief Medical Officer

Retrieved on:

Thursday, November 30, 2023

Dr. Liu joins Femasys as the company accelerates commercialization of its product pipeline, including a new therapeutic for artificial insemination, FemaSeed®.

Key Points:

Dr. Liu joins Femasys as the company accelerates commercialization of its product pipeline, including a new therapeutic for artificial insemination, FemaSeed®.
“With an exciting product pipeline and a culture focused on execution of the development and commercialization of differentiated women’s health procedures, Femasys stands apart in the industry,” said Dr. Liu.
He also served as the Division head, Reproductive Endocrinology and Infertility at the University of Cincinnati.
Ms. Kathy Lee-Sepsick, founder, president and chief executive officer of Femasys, commented on the appointment of Dr. Liu, stating, “It is a great pleasure to welcome Dr. James Liu to Femasys as the Company’s next chief medical officer.

Global Swine Artificial Insemination Market Analysis 2023-2030: Technological Advancements in AI Techniques Driving Industry Growth

Retrieved on:

Friday, August 11, 2023

Zoonosis, Genetics, COVID-19, Pig, Semen, USD, Chapter Three, Investment, PIC, Insemination, Health, Meat, Agriculture, Genus

The global swine artificial insemination market is projected to reach USD 3.16 billion by 2030, growing at a CAGR of 6.67% from 2023 to 2030.

Key Points:

The global swine artificial insemination market is projected to reach USD 3.16 billion by 2030, growing at a CAGR of 6.67% from 2023 to 2030.
Factors driving market growth include the increasing demand for pork products, advancements in artificial insemination technology, growing awareness about its benefits, and a focus on swine genetics.
The swine artificial insemination market is driven by factors like the increasing demand for pork products, advancements in technology, and supportive initiatives.
Overall, the market is expected to thrive in the coming years, fueled by the rising demand for pork and ongoing technological advancements in artificial insemination techniques.

Global Infertility Treatment Devices and Equipment Market Report 2023: Continuous Rise in Infertility Rates Drives Growth - ResearchAndMarkets.com

Retrieved on:

Monday, July 10, 2023

General Health, Health, Other Health, Prevalence, Semen, ART, Infertility, Fertility clinic, USD, IVF, CDC, Special Program of Assisted Reproduction, Korea Disease Control and Prevention Agency, Assisted reproductive technology, Growth, Patient, Insemination, Birth control

The "Infertility Treatment Devices And Equipment Market Size, Share & Trends Analysis Report 2023 - 2030" report has been added to ResearchAndMarkets.com's offering.

Key Points:

The "Infertility Treatment Devices And Equipment Market Size, Share & Trends Analysis Report 2023 - 2030" report has been added to ResearchAndMarkets.com's offering.
The global infertility treatment devices and equipment market size is expected to reach USD 555.2 million by 2030.
High adoption of Assisted Reproductive Technology (ART) is a significant driver in the market for infertility treatment devices & equipment.
The number of medical centers providing infertility treatment has increased over the past few years due to an increase in the prevalence of infertility cases around the world.

LGBTQ+ parents are being removed from their children’s birth certificates in Italy – here’s what’s behind this disturbing trend

Retrieved on:

Wednesday, June 28, 2023

The prosecutor, Valeria Sanzani, also seeks to remove the names of the mothers considered “non-genetic” from the birth certificates.

Key Points:

The prosecutor, Valeria Sanzani, also seeks to remove the names of the mothers considered “non-genetic” from the birth certificates.
This includes another case in Milan, in which the birth certificate of a child born abroad via surrogacy to two men was annulled.

Going back a few months

In April, the Milan prefecture extended the logic of the circular to same-sex couples who conceived abroad via insemination by a donor.
Also in April, the birth certificate of one child born to two mothers was annulled in the city of Bergamo.
The prosecutor has challenged the legitimacy of many more birth certificates, and going as far back as 2017 (the year after civil unions for same-sex couples were legalised in Italy).
The children, some as old as six, would have their names and parental status forcibly changed by an act of the state.

Moves from the Meloni government

While campaigning, Meloni made clear the stance that her government could be expected to have regarding LGBTQ+ rights.
In a 2022 rally in Spain, Meloni exclaimed: “Yes to the natural family!
No to the LGBT lobby!” The January circular marked the beginnings of the Meloni government’s actions to make good on such positions.

Problems with citizenship

Should Sanzari’s challenge be successful in court, the question will become: what to make of the children whose Italian citizenship derives from the non-genetic/gestational parent?
With the removal of non-genetic same-sex partners on birth certificates, there is a potential loss of citizenship for the children.

‘Protecting the children’

From drag queen story hour to gay marriage, many elements of LGBTQ+ inclusion have been framed as a threat to children.
Meloni’s government ran on a platform of protecting the family, attempting to connect conservative policies on LGBTQ+ inclusion and migration through the frame of defending a homeland and family.
One of her campaign slogans was “God, homeland, family.” An unfortunate irony, then, that this policy is proving so destructive to families.

Tractor Supply Company and Tractor Supply Company Foundation Support Farmer Veterans With $100,000 Donation

Retrieved on:

Tuesday, June 27, 2023

Tractor Supply Company (NASDAQ: TSCO ), the largest rural lifestyle retailer in the United States, and the Tractor Supply Company Foundation have donated $100,000 to Farmer Veteran Coalition’s (FVC) Fellowship Fund.

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Tractor Supply Company (NASDAQ: TSCO ), the largest rural lifestyle retailer in the United States, and the Tractor Supply Company Foundation have donated $100,000 to Farmer Veteran Coalition’s (FVC) Fellowship Fund.
“Our longstanding support for veterans is rooted in our core values of gratitude, integrity and community,” said Mary Winn Pilkington, president of the Tractor Supply Company Foundation.
“The Farmer Veteran Coalition is grateful for our long-time partnerships with Tractor Supply,” said Jeanette Lombardo, FVC executive director.
Fifty winners were awarded $1,000 Tractor Supply gift cards while an additional $50,000 grant from the Tractor Supply Company Foundation will benefit farmer veterans in the form of grants and through FVC programming.