FH

Evkeeza® (evinacumab-dgnb) sBLA for Children with Ultra-rare Inherited Form of High Cholesterol Accepted for FDA Priority Review

Retrieved on: 
Wednesday, November 30, 2022

TARRYTOWN, N.Y., Nov. 30, 2022 /PRNewswire/ -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the supplemental Biologics License Application (sBLA) for Evkeeza® (evinacumab-dgnb) as an adjunct to other lipid-lowering therapies to treat children aged 5 to 11 years with homozygous familial hypercholesterolemia (HoFH). The FDA target action date is March 30, 2023.

Key Points: 
  • HoFH is an ultra-rare inherited condition that affects approximately 1,300 patients in the U.S. and is the most severe form of familial hypercholesterolemia (FH).
  • The sBLA is supported by data from a three-part trial evaluating Evkeeza in children aged 5 to 11 years with HoFH.
  • The trial met its primary endpoint, showing children who added Evkeeza to other lipid-lowering therapies reduced their LDL-C by 48% at week 24 on average.
  • Part A (n=6) was a Phase 1b trial designed to assess the pharmacokinetics (PK), safety and tolerability of Evkeeza.

Emory Doctors and Family Heart Foundation Team Up to Help Patients with Dangerously High Cholesterol Caused by Genetic Condition

Retrieved on: 
Tuesday, November 29, 2022

Although its one of the most common genetic causes of early heart attacks and premature coronary heart disease, FH is dramatically underdiagnosed in patients.

Key Points: 
  • Although its one of the most common genetic causes of early heart attacks and premature coronary heart disease, FH is dramatically underdiagnosed in patients.
  • Without proper treatment, impacted individuals have up to a 20-fold increased risk of a heart attack or development of premature coronary artery disease.
  • As part of the new collaborative project, Emory Heart & Vascular Center will use the Family Heart Foundations innovative machine-learning technology, FIND FH , to identify and screen individuals at risk.
  • As a result of this mutation, cholesterol is not adequately cleared, leading to high levels of low-density lipoprotein cholesterol (LDL-C) or bad cholesterol in the bloodstream.

Grand Ming Group Holdings Limited Announces Interim Results for the Six Months Ended 30 September 2022

Retrieved on: 
Saturday, November 12, 2022

HONG KONG, Nov 12, 2022 - (ACN Newswire) - Grand Ming Group Holdings Limited (the "Company" and together with its subsidiaries, the "Group", stock code: 1271.HK) today announces its interim results for the six months ended 30 September 2022 ("FH 2022/23").

Key Points: 
  • HONG KONG, Nov 12, 2022 - (ACN Newswire) - Grand Ming Group Holdings Limited (the "Company" and together with its subsidiaries, the "Group", stock code: 1271.HK) today announces its interim results for the six months ended 30 September 2022 ("FH 2022/23").
  • The Group's consolidated revenue increased by 7.4 times from HK$586.1 million for the six months ended 30 September 2021 ("FH 2021/22") to HK$4,920.1 million for FH 2022/23.
  • Handover of the pre-sold units to buyers subsequently commenced in April 2022, with revenue of HK$4.77 billion recognised during FH 2022/23.
  • About Grand Ming Group Holdings Limited (Stock code: 1271.HK)
    The Group is principally engaged in the business of building construction, property leasing and property development.

EQS-News: Management Board change at FORTEC Elektronik AG

Retrieved on: 
Friday, November 11, 2022

FORTEC Elektronik AG has completed the succession process for Mr Bernhard Staller (62) who will retire on 30th June 2023 for age reasons.

Key Points: 
  • FORTEC Elektronik AG has completed the succession process for Mr Bernhard Staller (62) who will retire on 30th June 2023 for age reasons.
  • The Supervisory Board has appointed Ulrich Ermel (38) to the Management Board (COO) as of 1st March 2023 for a duration of 3 years.
  • Christoph Schubert, head of the Supervisory Board at FORTEC Elektronik AG: I am delighted that we have been able to bring Ulrich Ermel to FORTEC.
  • The FORTEC Elektronik AG Management Board will therefore comprise Sandra Maile, Chair of the Management Board along with Bernhard Staller and Ulrich Ermel, Members of the Management Board as of 1st March 2023.

Omron Announces REVTECH as Certified Systems Integrator Partner

Retrieved on: 
Tuesday, November 8, 2022

HOFFMAN ESTATES, Ill., Nov. 8, 2022 /PRNewswire-PRWeb/ -- Omron Automation Americas recently announced REVTECH as a new partner in its Certified Systems Integrator program. Based near Quebec City, REVTECH has been providing robotic and automation solutions for companies of various sizes across industries.

Key Points: 
  • Industry-leading automation solutions provider Omron Automation Americas welcomes new partner REVTECH SYSTEMS, an automation specialist with a young, dynamic team and leading-edge expertise.
  • HOFFMAN ESTATES, Ill., Nov.8, 2022 /PRNewswire-PRWeb/ -- Omron Automation Americas recently announced REVTECH as a new partner in its Certified Systems Integrator program.
  • The Omron Certified Systems Integrator program matches best-in-class solution providers with the technology, training, and resources required to deliver innovative and competitive solutions.
  • REVTECH also specializes in vision-based robot systems and connecting their solutions to data systems (ERP, database, RFID systems, technical files, etc.).

Family Heart Foundation Study Shows Significant Health Disparities in Treatment of Familial Hypercholesterolemia

Retrieved on: 
Monday, November 7, 2022

The Family Heart Foundation , a leading research and advocacy organization, shared results from an analysis of its large U.S. Family Heart DatabaseTM showing significant disparities exist in the treatment of familial hypercholesterolemia (FH) among racial groups, and by income and education levels.

Key Points: 
  • The Family Heart Foundation , a leading research and advocacy organization, shared results from an analysis of its large U.S. Family Heart DatabaseTM showing significant disparities exist in the treatment of familial hypercholesterolemia (FH) among racial groups, and by income and education levels.
  • These findings highlight the significant unmet need for improving equity and providing all individuals with FH an opportunity for cardiovascular risk reduction.
  • The observational study included patients diagnosed with FH and those likely to have FH but not yet diagnosed (probable FH).
  • Probable FH patients were identified by the Family Heart Foundations validated FIND-FH machine learning model.

Family Heart Foundation Study Shows Some Children With Homozygous Familial Hypercholesterolemia Miss out on Decades of Life-Saving Treatment

Retrieved on: 
Tuesday, October 11, 2022

The data raises the possibility that only children with the most severe cases of HoFH are being diagnosed early.

Key Points: 
  • The data raises the possibility that only children with the most severe cases of HoFH are being diagnosed early.
  • In addition, others who may have somewhat lower LDL-C are not identified early and miss out on decades of life-saving treatment, which could lead to heart disease earlier in life.
  • HoFH, a rare genetic condition characterized by extremely elevated levels of serum LDL-C, affects both children and adults.
  • There are two forms of FH: Heterozygous Familial Hypercholesterolemia and Homozygous Familial Hypercholesterolemia.

Two Volvo trucks fall head over wheels for each other in new film

Retrieved on: 
Tuesday, October 11, 2022

This is illustrated in the company's latest animated film, which centres on a love story between two Volvo FH trucks.

Key Points: 
  • This is illustrated in the company's latest animated film, which centres on a love story between two Volvo FH trucks.
  • The I-Save package was introduced to customers in 2019 and has since been a sales success for Volvo Trucks.
  • Volvo Trucks supplies complete transport solutions for professional customers with its full range of medium- and heavy-duty trucks.
  • Volvo Trucks is part of the Volvo Group.

Two Volvo trucks fall head over wheels for each other in new film

Retrieved on: 
Tuesday, October 11, 2022

This is illustrated in the company's latest animated film, which centres on a love story between two Volvo FH trucks.

Key Points: 
  • This is illustrated in the company's latest animated film, which centres on a love story between two Volvo FH trucks.
  • The I-Save package was introduced to customers in 2019 and has since been a sales success for Volvo Trucks.
  • Volvo Trucks supplies complete transport solutions for professional customers with its full range of medium- and heavy-duty trucks.
  • Volvo Trucks is part of the Volvo Group.

Omron showcases latest machine vision technology at the A3 Vision Show

Retrieved on: 
Friday, October 7, 2022

HOFFMAN ESTATES, Ill., Oct.  07, 2022 /PRNewswire-PRWeb/ -- Omron Automation Americas, a global leader in providing advanced automation solutions for sensing, control, safety, and vision technology, will showcase its most advanced machine vision cameras during the A3 Vision Show 2022 in Boston. This type of technology eliminates the need for high-end computing hardware or specialized engineers to configure a system to suit an application's requirements.

Key Points: 
  • Omron's comprehensive machine vision portfolio includes industrial cameras, vision systems, and PC-based cameras that are scalable across software platforms.
  • HOFFMAN ESTATES, Ill., Oct. 07, 2022 /PRNewswire-PRWeb/ -- Omron Automation Americas, a global leader in providing advanced automation solutions for sensing, control, safety, and vision technology, will showcase its most advanced machine vision cameras during the A3 Vision Show 2022 in Boston.
  • Omron's unique vision system demo includes direct-to-monitor GigE Vision and USB3 vision industrial cameras, smart cameras for defect analysis and code reading, and an FH vision system with AI for fine matching.
  • Omron vision expert Tad Newman is speaking at the event on the topic of quality inspection using machine vision with AI.