Metal toxicity

Siteman Cancer Center Begins Treatment with Latest Mevion Proton Therapy System

Retrieved on: 
Thursday, November 16, 2023

Mevion Medical Systems announced today that the world’s first single-room proton therapy system has completed the upgrade to the latest MEVION S250i Proton Therapy System® with FLASH* capabilities, and has begun treating patients in November at the S. Lee Kling Proton Therapy Center at Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, MO.

Key Points: 
  • Mevion Medical Systems announced today that the world’s first single-room proton therapy system has completed the upgrade to the latest MEVION S250i Proton Therapy System® with FLASH* capabilities, and has begun treating patients in November at the S. Lee Kling Proton Therapy Center at Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, MO.
  • View the full release here: https://www.businesswire.com/news/home/20231116635095/en/
    The MEVION S250i Proton Therapy System (Photo: Business Wire)
    Siteman Cancer Center is an NCI-designated Comprehensive Cancer Center that draws patients from Missouri, Southern Illinois and beyond.
  • “Our team also looks forward to advancing FLASH dosimetry research.”
    This latest system incorporates Mevion's cutting-edge HYPERSCAN® Pencil Beam Scanning for Intensity Modulated Proton Therapy (IMPT) with a proton MLC, along with an advanced 3D imaging system for high-precision Image-Guided Radiation Therapy (IGRT) and adaptive therapy.
  • These latest capabilities are the result of a collaborative effort between Mevion and Siteman Cancer Center, initiated in 2019.

Freeline Publishes Preclinical Proof-of-Concept Data for FLT190, its AAV Gene Therapy Candidate for Fabry Disease, in the Nature Journal Gene Therapy

Retrieved on: 
Thursday, January 19, 2023

LONDON, Jan. 19, 2023 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (Nasdaq: FRLN) today announced the publication of preclinical proof-of-concept data for its gene therapy candidate for Fabry disease, FLT190, in the Nature journal Gene Therapy. Fabry disease is a debilitating genetic disorder in which an enzyme deficiency leads to a harmful build-up of fat in the cells that causes progressive organ damage and can result in early death.

Key Points: 
  • Data show increased enzyme activity and reduction of harmful substrate, an established biomarker of efficacy in Fabry disease, in key tissues and organs
    LONDON, Jan. 19, 2023 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (Nasdaq: FRLN) today announced the publication of preclinical proof-of-concept data for its gene therapy candidate for Fabry disease, FLT190, in the Nature journal Gene Therapy.
  • “People living with Fabry disease can experience debilitating symptoms and disease progression, even with current treatments.
  • There is a pressing need for therapies with more lasting efficacy that are less burdensome on Fabry families,” said Pamela Foulds, M.D., Chief Medical Officer at Freeline.
  • The company expects to share initial safety and efficacy data from the second dose cohort of MARVEL-1, as well as updated data from the first cohort, in the first half of 2023.

Insights on the Stable Isotope Labeled Compounds Global Market to 2026 - Stable Isotope Studies Aid in Integration of Non-essential Amino Acids in Pea Aphids - ResearchAndMarkets.com

Retrieved on: 
Thursday, August 25, 2022

The "Stable Isotope Labeled Compounds - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Stable Isotope Labeled Compounds - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.
  • Stable isotope labelling comprises the use of non-radioactive isotopes which can act as tracers employed to model various chemical and biochemical systems.
  • Aside from their use in metabolomics research, stable isotope-labeled compounds are finding use in medical diagnostic research, proteomics, and environmental analysis.
  • Stable isotope labeled compounds is witnessing growing use in metabolism mediated toxicity research.

Global Heavy Metal Poisoning Market to 2030 - Insights, Epidemiology, and Forecasts - ResearchAndMarkets.com

Retrieved on: 
Friday, February 26, 2021

The "Heavy Metal Poisoning - Market Insights, Epidemiology, and Market Forecast - 2030" drug pipelines has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Heavy Metal Poisoning - Market Insights, Epidemiology, and Market Forecast - 2030" drug pipelines has been added to ResearchAndMarkets.com's offering.
  • The heavy metal poisoning market report provides analysis regarding current treatment practices, emerging drugs like Emeramide, potential therapies, market share of the individual therapies, and historical, current and forecasted Heavy Metal Poisoning market size from 2017 to 2030, segmented by seven major markets.
  • The Heavy Metal Poisoning epidemiology chapters provide insights about historical and current heavy metal poisoning patient pool and forecasted trend for every seven major countries.
  • Heavy metal poisoning epidemiology is segmented by total incident cases of heavy metal poisoning by age and by metal type.

Global Heavy Metal Poisoning Epidemiology Forecast Report 2017-2020 & 2021-2030 - ResearchAndMarkets.com

Retrieved on: 
Tuesday, February 23, 2021

The Heavy Metal Poisoning epidemiology report gives a thorough understanding of the heavy metal poisoning by including details such as disease definition, symptoms, causes, pathophysiology, and diagnosis.

Key Points: 
  • The Heavy Metal Poisoning epidemiology report gives a thorough understanding of the heavy metal poisoning by including details such as disease definition, symptoms, causes, pathophysiology, and diagnosis.
  • The heavy metal poisoning report and model provide an overview of the global trends of heavy metal poisoning in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).
  • The heavy metal poisoning epidemiology report will allow the user to:
    Develop business strategies by understanding the trends shaping and driving the heavy metal poisoning market.
  • Quantify patient populations in the global heavy metal poisoning market to improve product design, pricing, and launch plans
    The Heavy Metal Poisoning Epidemiology Model developed by the publisher is easy to navigate, interactive with dashboards, and epidemiology based with transparent and consistent methodologies.

Baby Food Attorney Taking Cases for Parents of Kids with Autism and ADHD

Retrieved on: 
Wednesday, February 10, 2021

LOS ANGELES, Feb. 10, 2021 /PRNewswire/ -- The law firm of Baum Hedlund Aristei & Goldman is accepting toxic baby food lawsuit cases on behalf of parents of children with autism and ADHD who purchased foods from several leading brands.

Key Points: 
  • LOS ANGELES, Feb. 10, 2021 /PRNewswire/ -- The law firm of Baum Hedlund Aristei & Goldman is accepting toxic baby food lawsuit cases on behalf of parents of children with autism and ADHD who purchased foods from several leading brands.
  • These toxic metals are associated with autism, autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in children.
  • The report also found that the companies knew their baby food products were tainted with high levels of toxic metals but decided to sell them anyway.
  • "The level of exposure to arsenic, lead, cadmium, and mercury known to be safe for infants is zero," attorney Pedram Esfandiary .

Heavy Metal Poisoning Pipeline Review, H2 2020 - Therapeutic Assessment of 5 Companies & 8 Drug Profiles - ResearchAndMarkets.com

Retrieved on: 
Wednesday, November 4, 2020

The "Heavy Metal Poisoning - Pipeline Review, H2 2020" drug pipelines has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Heavy Metal Poisoning - Pipeline Review, H2 2020" drug pipelines has been added to ResearchAndMarkets.com's offering.
  • Heavy Metal Poisoning - Pipeline Review, H2 2020, provides comprehensive information on the therapeutics under development for Heavy Metal Poisoning (Toxicology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
  • The Heavy Metal Poisoning (Toxicology) pipeline guide also reviews of key players involved in therapeutic development for Heavy Metal Poisoning and features dormant and discontinued projects.
  • Formulate corrective measures for pipeline projects by understanding Heavy Metal Poisoning (Toxicology) pipeline depth and focus of Indication therapeutics.

Pipeline Review for Heavy Metal Poisoning - H1 2020 - ResearchAndMarkets.com

Retrieved on: 
Tuesday, October 6, 2020

The "Heavy Metal Poisoning - Pipeline Review, H1 2020" drug pipelines has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Heavy Metal Poisoning - Pipeline Review, H1 2020" drug pipelines has been added to ResearchAndMarkets.com's offering.
  • This Pharmaceutical and Healthcare latest pipeline guide Heavy Metal Poisoning - Pipeline Review, H1 2020, provides comprehensive information on the therapeutics under development for Heavy Metal Poisoning (Toxicology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
  • The Heavy Metal Poisoning (Toxicology) pipeline guide also reviews of key players involved in therapeutic development for Heavy Metal Poisoning and features dormant and discontinued projects.
  • Formulate corrective measures for pipeline projects by understanding Heavy Metal Poisoning (Toxicology) pipeline depth and focus of Indication therapeutics.

Common Fireworks Release Toxic Metals Into the Air

Retrieved on: 
Thursday, July 2, 2020

These metals, which are used to give fireworks their vibrant color, also damage human cells and animal lungs.

Key Points: 
  • These metals, which are used to give fireworks their vibrant color, also damage human cells and animal lungs.
  • Led by researchers at NYU Grossman School of Medicine, the study showed harmful levels of lead in two of 12 types of commercially-available fireworks sampled.
  • They found that levels of toxic metals were higher in samples taken near Independence Day and New Year's Eve celebrations than at any other time of the year.
  • Gordon cautions that the current investigation is a first step, only addressing the potential effects of one-time exposure to the fireworks metals.

New Government of Canada regulations protect children from exposure to lead and cadmium

Retrieved on: 
Wednesday, May 2, 2018

That is why Health Canada is introducing new limits for toxic metals in children's products to protect children from exposure to lead and cadmium through updates to the Children's Jewellery Regulations and through new Consumer Products Containing Lead Regulations.

Key Points: 
  • That is why Health Canada is introducing new limits for toxic metals in children's products to protect children from exposure to lead and cadmium through updates to the Children's Jewellery Regulations and through new Consumer Products Containing Lead Regulations.
  • Exposure to lead or cadmium may pose a significant health risk to children who chew, suck or swallow items made with these metals.
  • Current science indicates that ingestion of even very low levels of lead or cadmium may be harmful to children.
  • To protect children from exposure to lead and cadmium in children's jewellery, Health Canada is:
    reducing the level of total allowable lead from 600 mg/kg to 90 mg/kg in children's jewellery; and
    introducing a strict 130 mg/kg total cadmium limit in these products.