ACT

Alpha Cancer Technologies Presents New Data from ACT-903, an AFP-Maytansine Conjugate, in Online Publication at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting

Retrieved on: 
Wednesday, May 31, 2023
Biotechnology, Health, Pharmaceutical, Clinical Trials, Oncology, ACT, Alpha-fetoprotein, American Journal of Clinical Oncology, Survival, AFP, Cancer, Immunomodulation, Research, ASCO, Journal, American Society of Clinical Oncology, Patient, Organoid, Annual general meeting, ADC, Neoplasm, Society, Safety, Medical imaging

The ASCO meeting will take place in Chicago from June 2-6, 2023.

Key Points: 
  • The ASCO meeting will take place in Chicago from June 2-6, 2023.
  • Now across multiple tumor models, we have observed high activity in treatment groups including statistically significant dose-dependent reduction in tumor volume and increased survival.
  • The research used an ovarian xenograft model compared to control with four dosing regimens of the AFP-maytansine conjugate, ACT-903.
  • ACT plans to submit an Investigational New Drug (IND) application for ACT-903 in 2024.

Digicel announces successful completion of its consent solicitation in respect of Digicel Limited Notes

Retrieved on: 
Monday, May 29, 2023
ACT, BY, AS, OR, Disclosure, SELL, SALE, Knowledge

Readers are cautioned not to place undue reliance on these materials and are referred to the Company's current public disclosure.

Key Points: 
  • Readers are cautioned not to place undue reliance on these materials and are referred to the Company's current public disclosure.
  • This material may contain certain "forward-looking statements" and information relating to the Company and its affiliates that reflects the current views and/or expectations of the Company and its management with respect to future events.
  • Such statements are subject to a number of risks, uncertainties and assumptions.
  • ANY PUBLIC OFFERING OF SECURITIES IN THE UNITED STATES WILL BE MADE BY MEANS OF A PROSPECTUS.

Inside information: Citycon Oyj announces the results of its tender offer for outstanding notes due 2024 of Citycon Treasury B.V.

Retrieved on: 
Monday, May 29, 2023
ACT, ISLAND, AS, NOT, FOR, Interest, WAKE, SEE, EUR, ITS, ANY, ISIN, Cryptocurrency

HELSINKI, May 29, 2023 /PRNewswire/ -- On 22 May 2023, Citycon Oyj (the "Company") launched its invitation to holders of the EUR 457,617,000 2.50 per cent Guaranteed Notes due 2024 of Citycon Treasury B.V. guaranteed by the Company (ISIN: XS1114434167) issued in separate tranches on 1 October 2014 and 10 June 2020 (the "Securities"), to tender such Securities for purchase by the Company for cash (the "Offer"), on the terms and subject to the conditions set out in the tender offer memorandum dated 22 May 2023 (the "Tender Offer Memorandum") prepared by the Company. The Offer remains subject to the offer and distribution restrictions set out in the Tender Offer Memorandum. Capitalised terms used in this announcement but not defined have the meanings given to them in the Tender Offer Memorandum.The Company today announces that it will accept for purchase EUR 138,275,000 in aggregate principal amount of Securities validly tendered pursuant to the Offer. The total purchase consideration (including Accrued Interest Payments) for Securities validly tendered and accepted for purchase pursuant to the Offer will be EUR 137,110,080.32 (the "Total Purchase Consideration"), which will be funded by cash on the Company's balance sheet.The final results of the Offer are as follows:

Key Points: 
  • PERSON (AS DEFINED IN REGULATION S OF THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT")) OR IN OR INTO ANY OTHER JURISDICTION WHERE IT IS UNLAWFUL TO RELEASE, PUBLISH OR DISTRIBUTE THIS DOCUMENT (SEE "OFFER AND DISTRIBUTION RESTRICTIONS" IN THE TENDER OFFER MEMORANDUM).
  • The Offer remains subject to the offer and distribution restrictions set out in the Tender Offer Memorandum.
  • Capitalised terms used in this announcement but not defined have the meanings given to them in the Tender Offer Memorandum.
  • The Company today announces that it will accept for purchase EUR 138,275,000 in aggregate principal amount of Securities validly tendered pursuant to the Offer.

Lehrmann inquiry: what's a director of public prosecutions or DPP? A legal expert explains

Retrieved on: 
Saturday, May 27, 2023
ACT, Rape, Human, Democracy, Crime, Persecution, Politics, Fear, Director of Public Prosecutions (Ireland), Parliament House, DPP, Government, Retirement, Shane Drumgold, Risk, Police, 1922 Bulgarian war criminal prosecution referendum, 2021 Australian Parliament House sexual misconduct allegations, Commonwealth, Debra Lehrmann, DPP v Santana-Bermudez, Private investigator, Birth control, Audit, Drug, District attorney, Crown

Every Australian state and territory, and the Commonwealth itself, has a Director of Public Prosecutions (DPP).

Key Points: 
  • Every Australian state and territory, and the Commonwealth itself, has a Director of Public Prosecutions (DPP).
  • Their main role is to initiate and conduct prosecutions of serious crimes in the superior courts.
  • If police charge a suspect for a serious crime, they prepare a brief of evidence and provide it to the office of the DPP.
  • If the prosecutor decides to prosecute a serious crime, the lives of the defendant and the victim are changed forever.
  • Reasonable minds often differ on prosecutorial decisions, and disagreement can be a healthy “check and balance” within the system.

What is a DPP?

    • They sell their worth to voters by showing themselves to be “tough on crime” and on the people who commit crime.
    • They should only prosecute a case if it’s in the public interest and there’s a reasonable prospect of a conviction.
    • The outcome of any trial must be fair and just, and not simply a “notch in the belt” of a prosecutor.

Political dilemma

    • An increasingly cynical public had trouble accepting that an attorney-general could really make decisions about prosecutions without being influenced by the political consequences for themselves, their party or their government.
    • So there’s a balancing issue: how to make sure prosecutorial decisions are not so political that they are made in the short-term interests of governments, but political enough that they reflect community standards.
    • To put the dilemma in legal terms, how do we achieve independence, accountability and the public interest in prosecutorial decisions?

An odd compromise

    • The question is answered in Australia by way of a rather odd compromise.
    • The DPP makes prosecutorial decisions in a statutory office independent of politics, but the DPP is appointed by the governor, who is advised by the government.
    • DPPs are appointed for limited terms (unlike judges who are appointed until retirement), so if they displease the government, they may not be reappointed.

Electricity prices are rising again. Here's how to ensure renters can cash-in on rooftop solar

Retrieved on: 
Saturday, May 27, 2023
ACT, Exercise, Technology, Housing, Industry, Teaching, Perception, Policy, Research, Attention, Australian Energy Regulator, Carbon, Sale, Government, Bill shock, Cooking, Heat, Federation, Renewable energy, Lease, Renting, Property management

For the one in three Australian homes with rooftop solar, the bill shock will be reduced – together with their carbon emissions.

Key Points: 
  • For the one in three Australian homes with rooftop solar, the bill shock will be reduced – together with their carbon emissions.
  • But households without solar, such as renters and social housing tenants, are missing out on the benefits.
  • New measures are needed to make sure renters benefit from solar technology – both through lower bills, and more liveable homes.

Solar haves and solar have-nots

    • But as of 2017-2018, there was only a 3-4% chance a rental property had solar panels on the roof.
    • The conventional view is that two main barriers exist to solar being installed on rentals.
    • Until now, efforts to increase solar on rental properties have focused on reducing this cost through subsidies and low-interest finance.
    • This involved a ranking exercise where landlords selected the most and least important reasons for not yet putting solar panels on their rental home.

Our findings

    • They ranked it as one of two top reasons why they hadn’t installed rooftop panels.
    • But when offered a choice of hypothetical policy options, about two-thirds opted for upfront payment of solar systems rather than an interest-free loan.
    • Our research also examined barriers for apartment landlords when it comes to energy efficiency upgrades and installing solar panels.
    • Read more:
      Check your mirrors: 3 things rooftop solar can teach us about Australia's electric car rollout

So what next?

    • Property managers have relationships with both landlords and tenants, and deep knowledge of the rental market.
    • Resources could, for instance, be invested into teaching property managers about the benefits of rooftop solar and energy efficiency upgrades.
    • Additional incentives could be provided to investors and property managers who, say, make a home less reliant on gas over time.
    • Lee White received funding from Energy Consumers Australia (APAPR21003) for the research on solar for rental properties discussed in this piece.
    • The views expressed in this document do not necessarily reflect the views of Energy Consumers Australia.

AltaPointe Health Celebrates the Ribbon Cutting of its Newest Facility in Clay County

Retrieved on: 
Friday, May 26, 2023
ACT, Alabama Department of Public Health, Health, Initiative, Mental health, Associate, Alabama Department of Mental Health, Talladega, MD, Patient, Mental, Clay County Hospital, Hospital, Environment, Safety, NJIT Steel Bridge Team, Nursing

ASHLAND, Ala., May 26, 2023 /PRNewswire-PRWeb/ -- AltaPointe Health, a leading provider of comprehensive mental health services, is pleased to announce the official ribbon-cutting ceremony for its brand-new clinic in Clay County. The Ashland, AL facility marks a significant milestone in the organization's ongoing commitment to improving access to mental healthcare.

Key Points: 
  • AltaPointe Health, a leading provider of comprehensive mental health services, is pleased to announce the official ribbon-cutting ceremony for its brand-new clinic in Clay County.
  • ASHLAND, Ala., May 26, 2023 /PRNewswire-PRWeb/ -- AltaPointe Health, a leading provider of comprehensive mental health services, is pleased to announce the official ribbon-cutting ceremony for its brand-new clinic in Clay County.
  • "The building is an investment in the community and shows AltaPointe's commitment to providing the utmost in mental healthcare to the people of Clay County," said Tuerk Schlesinger, AltaPointe Health CEO.
  • Clay County now offers more services than before AltaPointe and Cheaha Mental Health Center merged in 2016.

Form 8.3 - The Vanguard Group, Inc.: Horizon Therapeutics plc

Retrieved on: 
Saturday, May 27, 2023
ACT, Disclosure, IRISH, Life insurance

OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER

Key Points: 
  • OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER
    Owner or controller of interests and short positions disclosed, if different from 1(a)
    The naming of nominee or vehicle companies is insufficient.
  • For a trust, the trustee(s), settlor and beneficiaries must be named.
  • If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)
    For an opening position disclosure, state the latest practicable date prior to the disclosure
    In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer?
  • If it is a cash offer or possible cash offer, state “N/A”
    If there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.

Form 8.3 - The Vanguard Group, Inc.: Horizon Therapeutics plc

Retrieved on: 
Saturday, May 27, 2023
ACT, Disclosure, IRISH, Life insurance

OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER

Key Points: 
  • OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER
    Owner or controller of interests and short positions disclosed, if different from 1(a)
    The naming of nominee or vehicle companies is insufficient.
  • For a trust, the trustee(s), settlor and beneficiaries must be named.
  • If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)
    For an opening position disclosure, state the latest practicable date prior to the disclosure
    In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer?
  • If it is a cash offer or possible cash offer, state “N/A”
    If there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.

Form 8.3 - The Vanguard Group, Inc.: Horizon Therapeutics plc

Retrieved on: 
Saturday, May 27, 2023
ACT, Disclosure, IRISH, Life insurance

OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER

Key Points: 
  • OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER
    Owner or controller of interests and short positions disclosed, if different from 1(a)
    The naming of nominee or vehicle companies is insufficient.
  • For a trust, the trustee(s), settlor and beneficiaries must be named.
  • If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)
    For an opening position disclosure, state the latest practicable date prior to the disclosure
    In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer?
  • If it is a cash offer or possible cash offer, state “N/A”
    If there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.

Form 8.3 - The Vanguard Group, Inc.: Horizon Therapeutics plc

Retrieved on: 
Saturday, May 27, 2023
ACT, Disclosure, IRISH, Life insurance

OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER

Key Points: 
  • OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER
    Owner or controller of interests and short positions disclosed, if different from 1(a)
    The naming of nominee or vehicle companies is insufficient.
  • For a trust, the trustee(s), settlor and beneficiaries must be named.
  • If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)
    For an opening position disclosure, state the latest practicable date prior to the disclosure
    In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer?
  • If it is a cash offer or possible cash offer, state “N/A”
    If there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.