Blood pressure

Alnylam Presents Positive Results from the KARDIA-2 Phase 2 Study of Zilebesiran Added to Standard of Care Antihypertensives in Patients with Inadequately Controlled Hypertension

Retrieved on: 
Sunday, April 7, 2024

Zilebesiran is an investigational RNAi therapeutic targeting liver-expressed angiotensinogen (AGT) in development for the treatment of hypertension with the potential for biannual dosing.

Key Points: 
  • Zilebesiran is an investigational RNAi therapeutic targeting liver-expressed angiotensinogen (AGT) in development for the treatment of hypertension with the potential for biannual dosing.
  • The results were presented today as a late-breaking clinical trial at the 2024 American College of Cardiology (ACC) Annual Scientific Session.
  • The Company previously announced positive topline results from the KARDIA-2 study in March 2024.
  • “Although many effective oral treatments are available, a large proportion of patients with hypertension are not managed to guideline-recommended targets.

NeuroCatch Introduces PeakSelect, Enabling a Deeper Clinical Dive into Brain Vital Signs at a Doctor's Office Near You

Retrieved on: 
Tuesday, April 9, 2024

BOSTON, April 9, 2024 /PRNewswire/ -- NeuroCatch Inc., a leading medical device company that enables rapid access to an objective assessment of brain health at the point of care, today announced the release of PeakSelect, an innovative software tool designed to improve clinical decision making. An enhancement to the NeuroCatch Platform, PeakSelect allows users to evaluate specific brain vital sign responses for precision medicine in patients undergoing portable neuro-physiological brain function assessment.

Key Points: 
  • An enhancement to the NeuroCatch Platform, PeakSelect allows users to evaluate specific brain vital sign responses for precision medicine in patients undergoing portable neuro-physiological brain function assessment.
  • "The first of an ongoing cadence of planned software upgrades, PeakSelect enhances the impact of NeuroCatch's brain health vital sign data to inform better clinical decision-making, more robust clinical trials, and more effective training regimes."
  • Through regular, over-the-air updates, NeuroCatch is continually advancing the powerful impact of brain vital sign monitoring for frontline health impacts.
  • "The NeuroCatch platform has already proven itself a breakthrough device with its mobile ability, rapid analysis and sophisticated sensitivity to analyze brain vital sign data.

How to keep your kidneys healthy – and how to spot when things are going wrong

Retrieved on: 
Tuesday, April 9, 2024

To keep your kidneys healthy there are several things you can do to help yourself.

Key Points: 
  • To keep your kidneys healthy there are several things you can do to help yourself.
  • Don’t let your kidneys dry out; make sure you drink a decent amount of fluid every day.
  • Drinking water is the best way to keep your kidneys hydrated, but any fluid such as tea or fruit-flavoured drinks are fine.
  • Smoking is bad for your kidneys, as it closes up the blood vessels in the kidneys and also increases blood pressure.

Musicians On Call’s Programs Expand Nationwide to Deliver the Healing Power of Music to Hospitals When Needed Most

Retrieved on: 
Monday, March 25, 2024

Through Musicians On Call’s bedside and virtual programs, patients experience the physical, mental and emotional benefits of live music in the hospital setting.

Key Points: 
  • Through Musicians On Call’s bedside and virtual programs, patients experience the physical, mental and emotional benefits of live music in the hospital setting.
  • “For nearly four years, volunteer and visitor restrictions in local hospitals paused Musicians On Call’s in-person programs.
  • “Our commitment to enhancing the hospital environment through the transformative power of music continues as the demand for our programs grows.
  • As the nation’s leading provider of live music in hospitals, MOC volunteers have performed for more than one million individuals in healthcare facilities nationwide.

Keep America Beautiful Kicks off the 2024 Great American Cleanup

Retrieved on: 
Tuesday, March 19, 2024

Stamford, CT, March 19, 2024 (GLOBE NEWSWIRE) -- Keep America Beautiful® today officially kicks off its 2024 Great American Cleanup®, the annual spring-cleaning event in which 300,000 Americans are expected to take part in activities to pick up litter and green their communities between now and the first day of summer.

Key Points: 
  • Stamford, CT, March 19, 2024 (GLOBE NEWSWIRE) -- Keep America Beautiful® today officially kicks off its 2024 Great American Cleanup®, the annual spring-cleaning event in which 300,000 Americans are expected to take part in activities to pick up litter and green their communities between now and the first day of summer.
  • “Thanks to our amazing volunteers, we set a cleanup record in 2023, and we’re aiming to break that record in 2024,” said Keep America Beautiful President and CEO Jennifer Lawson.
  • But Keep America Beautiful officials say the impact of the cleanup goes far beyond simply making communities look nicer.
  • Sponsors for the 2024 Great American Cleanup include Altria, Cox, Diageo, Dow, McDonald's, Reynolds American, Santa Fe Natural Tobacco Company, and Yuengling.

ONWARD® Medical Reaffirms Guidance, Shares 2024 Strategic Priorities, and Releases Unaudited Q4 Financial Highlights

Retrieved on: 
Friday, March 15, 2024

The Company expects to launch its investigational ARC-EX Therapy to improve the strength and function of the upper extremities after SCI in the US in Q4 2024.

Key Points: 
  • The Company expects to launch its investigational ARC-EX Therapy to improve the strength and function of the upper extremities after SCI in the US in Q4 2024.
  • Major associated milestones this year include FDA De Novo submission, FDA clearance, and first commercial sale.
  • The Company plans to publish its Full Year 2023 financial statements on April 25, 2024.
  • Net cash outflow in Q4, 2023 was EUR 7.0 million, consistent with the EUR 7.0M cash burn in Q3, 2023.

Aquestive Therapeutics Announces Pivotal Study for Anaphylm™ (epinephrine) Sublingual Film Successfully Meets Primary and Secondary Endpoints and Provides Clinical Development Update Following FDA Meeting

Retrieved on: 
Thursday, March 14, 2024

“We are extremely pleased with the pivotal study results as well as our recent FDA interaction,” said Daniel Barber, President and Chief Executive Officer of Aquestive.

Key Points: 
  • “We are extremely pleased with the pivotal study results as well as our recent FDA interaction,” said Daniel Barber, President and Chief Executive Officer of Aquestive.
  • “We believe we have a clear understanding of the remaining clinical development steps necessary for a pre-NDA meeting with the FDA in the second half of the year.
  • These latest study results show that the sublingual administration of epinephrine provides rapid and sustained levels of epinephrine similar to approved treatments.
  • The FDA noted that substantial progress had been made in the Anaphylm clinical development program and did not outline any new clinical development requirements.

Orchestra BioMed Demonstrates Strength of Cardiovascular Pipeline with Virtue® SAB and AVIM Therapy Presentations at CRT 2024 Annual Meeting

Retrieved on: 
Wednesday, March 13, 2024

A second presentation featured recently reported clinical data on atrioventricular interval modulation (“AVIM”) therapy (also known as BackBeat CNT), an investigational therapy delivered via standard dual-chamber pacemakers designed to immediately, substantially and persistently lower blood pressure.

Key Points: 
  • A second presentation featured recently reported clinical data on atrioventricular interval modulation (“AVIM”) therapy (also known as BackBeat CNT), an investigational therapy delivered via standard dual-chamber pacemakers designed to immediately, substantially and persistently lower blood pressure.
  • The AVIM presentation also outlined the design of the currently enrolling BACKBEAT global pivotal study evaluating AVIM therapy in hypertensive pacemaker patients in collaboration with Medtronic.
  • Specifically, the presented PK data showed that:
    Molecular weight of Sostenocel remained unchanged prior to elimination, showing no evidence of in-vivo degradation.
  • AVIM therapy demonstrated:
    Consistent favorable hemodynamic effects using both conduction system, as well as traditional right ventricular lead placements.

Olfactive Biosolutions Files Patent to Repurpose Food Molecules to Safely, Inexpensively Regulate Blood Pressure

Retrieved on: 
Tuesday, April 2, 2024

The Protenx patent also allows for administration including but not limited to topically, sublingual lozenges, inhaled or administered in multiple other ways.

Key Points: 
  • The Protenx patent also allows for administration including but not limited to topically, sublingual lozenges, inhaled or administered in multiple other ways.
  • “We are replacing prescription pharmaceuticals with common food molecules, creating a new, inexpensive, easy-to-digest category of health care solutions,” said Nils Lommerin, President and CEO of Olfactive Biosolutions.
  • “We believe regulating blood pressure is an important aspect of people’s health, and we are excited to have filed a new patent for Protenx to safely and inexpensively replace pharmaceuticals that currently control blood pressure in millions of people worldwide.
  • “Adding the patent for controlling blood pressure to the Protenx products for weight loss, with new products for other conditions to come, establishes us as the leader in the food as pharmaceuticals category of health care.

Global Medical Adhesives & Sealants Market Report 2024 - Wide Array of Solutions and Application Areas Offered by Soft-Skin Adhesives Facilitating Market Growth - ResearchAndMarkets.com

Retrieved on: 
Monday, April 1, 2024

The "Global Medical Adhesives & Sealants Market - Resin Types, Applications and End-use Sectors" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Medical Adhesives & Sealants Market - Resin Types, Applications and End-use Sectors" report has been added to ResearchAndMarkets.com's offering.
  • The growth in demand for soft-skin adhesives has been made possible by the wide variety of their applications in the medical, pharmaceutical and personal care areas.
  • Soft-skin adhesives find application in a range of medical areas, which comprise skin therapies, wound dressing and wearable medical devices, providing further impetus to demand for them.
  • The range of applications for adhesives and sealants the medical sector includes the areas of dentistry & cosmetics, internal & external surgery and medical devices & equipment.