Polycystic ovary syndrome

Spruce Biosciences Reports Full Year 2023 Financial Results and Provides Corporate Updates

Retrieved on: 
Wednesday, March 13, 2024

(Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need, today reported financial results for the year ended December 31, 2023 and provided corporate updates.

Key Points: 
  • (Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need, today reported financial results for the year ended December 31, 2023 and provided corporate updates.
  • “We are grateful to all the patients, families, study team and investigators who supported the CAHmelia-203 clinical trial,” said Javier Szwarcberg, M.D., M.P.H., Chief Executive Officer, Spruce Biosciences.
  • Non-cash stock-based compensation expense for the year ended December 31, 2023 was $4.6 million compared to $3.6 million in 2022.
  • Net Loss: Net loss for the year ended December 31, 2023 was $47.9 million compared to $46.2 million in 2022.

CCRM FERTILITY WELCOMES REGIONAL DIRECTOR OF CLINICAL REPRODUCTIVE GENETICS, DR. JASMINE ALY, TO JERSEY CITY TEAM

Retrieved on: 
Wednesday, March 27, 2024

JERSEY CITY, N.J., March 27, 2024 /PRNewswire/ -- CCRM Fertility, a leading pioneer in the fertility treatment, research, and science industry, announced today that Jasmine Aly, MD, FACOG, will be joining  CCRM | IRMS in New Jersey. Dr. Aly holds the rare distinction of being a triple-specialized physician as an Obstetrician-Gynecologist, Reproductive Endocrinologist, and Medical Geneticist.

Key Points: 
  • JERSEY CITY, N.J., March 27, 2024 /PRNewswire/ -- CCRM Fertility, a leading pioneer in the fertility treatment, research, and science industry, announced today that Jasmine Aly, MD, FACOG, will be joining  CCRM | IRMS in New Jersey.
  • As Regional Director of Clinical Reproductive Genetics, Dr. Aly will bring her expertise to the CCRM Fertility team and aims to leverage her comprehensive fellowship training in genetics to further advance the field and better serve patients.
  • As an esteemed reproductive endocrinologist, she will utilize cutting-edge  technology and innovative scientific techniques to ensure patient success rates continue to rise.
  • "Dr. Aly's expertise in genetics is an invaluable attribute that will redefine care at CCRM | IRMS," notes CCRM Fertility CEO, Bob LaGalia.

It’s time for a heart-to-heart about women’s cardiovascular health, unique risk factors and symptoms

Retrieved on: 
Sunday, February 11, 2024

Cardiovascular disease — also called heart disease — is a condition affecting the heart and blood vessels, and is the leading cause of death among women worldwide.

Key Points: 
  • Cardiovascular disease — also called heart disease — is a condition affecting the heart and blood vessels, and is the leading cause of death among women worldwide.
  • In fact, a women dies of heart disease every 20 minutes in Canada.
  • Although cardiovascular disease is often considered a disease of men, women are more likely to die from a heart attack when compared with men.

Women’s hearts are different

  • From the outside, women’s hearts may look the same as men’s, but there are important differences.
  • Specifically, women experience unique events over the course of their lifespan which may impact their cardiovascular health.
  • Pregnancy complications, such as hypertensive disorders of pregnancy and gestational diabetes, can also play a role in cardiovascular health.

Heart attack symptoms

  • Early heart attack symptoms are missed in up to 78 per cent of women, in part related to the fact that women may present with different symptoms than men.
  • An awareness of the differences in heart attack symptoms may lead to improved recognition and timely care for women.

Reducing heart risks

  • There are many steps that you can take to reduce your risk of heart disease.
  • Living free from commercial tobacco and vaping, reducing alcohol intake and managing stress are also key ways to reduce your risk.

Wear red and learn more

  • On Feb. 13, we invite you to celebrate Wear Red Canada to raise awareness for women’s cardiovascular health, hosted by the Canadian Women’s Heart Health Alliance and the Canadian Women’s Heart Health Centre.
  • Attend free presentations and webinars by Canadian experts, join the Wear Red Canada Movement Challenge and take part in local events.


Nabilah Gulamhusein has received funding from the Canadian Institutes of Health Research through the Canada Graduate Scholarship - Master’s. Sandi Dumanski receives funding from the Canadian Fertility and Andrology Society and the Kidney Foundation.

Your skin is a mirror of your health – here’s what yours might be saying

Retrieved on: 
Tuesday, January 30, 2024

It is the largest and most visible organ in the human body.

Key Points: 
  • It is the largest and most visible organ in the human body.
  • Being the most visible of our organs, the skin also offers us a view into the body tissues that it protects.
  • So don’t think of your skin merely aesthetically – think of it as a reflection of your health.

Bullseye

  • But while the vast majority of tick bites won’t make you ill, there is one rash that should prompt a visit to your doctor if you spot it.
  • Erythema migrans, a rash named for its ability to rapidly expand across the skin, is a hallmark of Lyme disease, a potentially severe bacterial illness.
  • This rash forms a classic target pattern, like a bullseye on a dartboard.

Purpura

  • Some rashes are given a colourful namesake – purpura is one such example.
  • Purpura refers to a rash of small purple or red dots.
  • Purpura signals an issue with either the walls of the tiny blood vessels that feed the skin or the blood within them.

Skin spiders


Skin rashes can also take on recognisable shapes. Spider naevi represent an issue within skin arterioles (small arteries which supply the skin with blood). Arterioles open and close to control the loss of heat from the body’s surface. But sometimes they can get stuck open – and a spider-like pattern will appear.

  • Crush the body under a fingertip and the whole thing disappears, as your touch temporarily stops the blood flow.
  • Treat the underlying cause, and the spiders often vanish with time – though they may persist or reappear later.

Black velvet

  • This “black velvet” skin appearance is more commonly seen in darker skins.
  • Usually, the condition is associated with disorders of the metabolism – namely type 2 diabetes and polycystic ovary syndrome.

Butterfly rashes

  • Cardiac valves have the important role of correctly directing the journey of blood through the heart and preventing backflow.
  • The body’s natural response is to preserve core blood volume, shutting off flow towards the skin.
  • The net effect can produce a purple-red rash, high across the cheeks and the bridge of the nose, like the outstretched wings of a butterfly.


Dan Baumgardt does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Metabolon Wins National Institute of Health (NIH) Award to Develop Test to Improve Polycystic Ovary Syndrome (PCOS) Diagnostic Accuracy

Retrieved on: 
Tuesday, December 5, 2023

MORRISVILLE, N.C., Dec. 5, 2023 /PRNewswire/ -- Metabolon, Inc., the global leader in providing metabolomics solutions advancing a wide variety of life science research, diagnostic, therapeutic development, and precision medicine applications, today announced receipt of a National Institute of Health (NIH) award to improve the accuracy by which polycystic ovary syndrome (PCOS) can be diagnosed.

Key Points: 
  • PCOS is the most common cause of infertility worldwide, affecting an estimated 8-13% of women of childbearing age.
  • Current diagnoses typically require pelvic exams and blood tests to obtain a hormone profile, glucose tolerance, and lipid measurements.
  • This diagnostic algorithm likely misclassifies or outright misses a lot of cases," said Adam Kennedy, Associate Director of Research and Development at Metabolon.
  • "Metabolon's work in this area will potentially bring PCOS diagnostic guidelines into the 21st century using highly advanced, cutting-edge metabolomics science."

Allara Raises $10M in Series A Funding Led by GV (Google Ventures) to Bridge the Care Gap for Women with Chronic Hormonal Conditions

Retrieved on: 
Wednesday, October 18, 2023

NEW YORK, Oct. 18, 2023 /PRNewswire/ -- Allara, a first-of-its-kind virtual care platform bridging the care divide for the millions of women of reproductive age dealing with chronic hormonal conditions, today announced $10 million in Series A funding led by GV (Google Ventures), with participation from Great Oaks Venture Capital, Humbition, Vanterra, Gaingels, and individual investors, including Tom Lee (One Medical) and Maggie Sellers. GV General Partner Frédérique Dame also joins Allara's Board of Directors.

Key Points: 
  • Allara's pioneering care platform pairs patients with specially trained expert doctors and registered dietitians for ongoing care to fill a significant gap in women's healthcare.
  • Over 1 in 3 women live with a chronic condition such as polycystic ovary syndrome (PCOS), endometriosis, or hypothyroidism.
  • Allara recognized these gaps as a call to help women with chronic conditions feel seen, heard, and treated with specialized care.
  • "Women of reproductive age have complex hormonal care needs, and Allara raises the bar for clinically driven, personalized hormonal healthcare," said GV General Partner Frédérique Dame.

Ulike Launches Social Impact Initiatives To Support The PCOS Community During PCOS Awareness Month

Retrieved on: 
Friday, September 29, 2023

NEW YORK, Sept. 29, 2023 /PRNewswire-PRWeb/ -- Ulike, the leading at-home IPL hair removal brand, is supporting Polycystic Ovary Syndrome (PCOS) warriors in honor of PCOS Awareness Month (September) with their We See You campaign. Ulike is dedicated to raising awareness around and providing supportive solutions to Hirsutism, a side effect of the condition that causes excessive hair growth.

Key Points: 
  • In honor of PCOS Awareness Month, Ulike is launching several initiatives to provide holistic support to the PCOS community.
  • Ulike is committed to raising awareness for the community through the following initiatives this September:
    PCOS Warrior Social Campaign & Documentary: Ulike is partnering with members of the PCOS community to create an empowering social campaign and documentary in September.
  • PCOS CON Event Sponsorship: Ulike is proud to be a main sponsor at the upcoming PCOS CON in California to amplify awareness, foster community engagement, and provide valuable resources to those affected by PCOS.
  • Ulike is proud to support those suffering with PCOS through these thoughtful initiatives and is dedicated to raising awareness on these important topics throughout the year.

HRC Fertility Center Adds Hakman and Wertheimer to Roster of Award-Winning Physicians

Retrieved on: 
Thursday, September 28, 2023

HRC Fertility Center , one of the largest providers of advanced fertility treatments based in Southern California, today announced the addition of Sasha Hakman, MD and Sahar Wertheimer, MD , to its team of award-winning physicians.

Key Points: 
  • HRC Fertility Center , one of the largest providers of advanced fertility treatments based in Southern California, today announced the addition of Sasha Hakman, MD and Sahar Wertheimer, MD , to its team of award-winning physicians.
  • Effective immediately, Dr. Hakman and Dr. Wertheimer, both highly sought-after Reproductive Endocrinologist and Infertility Specialists, have joined the center’s West Los Angeles office.
  • Dr. Hakman has a longstanding family and personal history of infertility and Polycystic Ovary Syndrome (PCOS).
  • Dr. Hakman is a subject matter expert for the American Board of OB-GYN, and serves as HRC Fertility’s baby center medical advisor.

OM1 Launches Hidradenitis Suppurativa Dataset to Expand Real-World Evidence in Dermatology

Retrieved on: 
Thursday, September 21, 2023

OM1 a leading real-world data, AI and technology company with a focus on chronic diseases, today announced the continued expansion of its Dermatology Network to include Hidradenitis Suppurativa (HS) , a systemic inflammatory disease, enhancing the dataset with almost 26,000 patient records.

Key Points: 
  • OM1 a leading real-world data, AI and technology company with a focus on chronic diseases, today announced the continued expansion of its Dermatology Network to include Hidradenitis Suppurativa (HS) , a systemic inflammatory disease, enhancing the dataset with almost 26,000 patient records.
  • Studies continue to show the link between skin conditions and mental health.
  • With one in four Americans impacted by a skin disease, combined with the increasing mental health epidemic, it’s critical to uncover and introduce solutions that will ultimately improve health outcomes.
  • “People are going years without an accurate diagnosis of their dermatological conditions, resulting in a worsening of both the disease and the patient’s mental health,” said Stefan Weiss, MD, MBA, FAAD Managing Director of Dermatology at OM1.

Reproductive Endocrinologist Dr. Bana Kashani Shares Advice for Women Trying to Conceive with PCOS during PCOS Awareness Month

Retrieved on: 
Tuesday, September 19, 2023

According to the Centers for Disease Control and Prevention (CDC), one in ten women in their childbearing years have PCOS; however, 70% of cases are undiagnosed.

Key Points: 
  • According to the Centers for Disease Control and Prevention (CDC), one in ten women in their childbearing years have PCOS; however, 70% of cases are undiagnosed.
  • In light of PCOS Awareness Month, Banafsheh Kashani , M.D., OB-GYN, reproductive endocrinologist and infertility specialist, is sharing her top tips for women trying to conceive with PCOS.
  • “Conceiving with PCOS can be a complex and emotional journey for the millions of women affected,” says Dr. Kashani.
  • However, research shows that losing just 5-10% of body weight can significantly improve fertility in women with PCOS.