Life expectancy

Sibeprenlimab Receives U.S. FDA Breakthrough Therapy Designation for the Treatment of Immunoglobulin A Nephropathy

Retrieved on: 
Friday, February 16, 2024

Otsuka Pharmaceutical Development & Commercialization, Inc., (OPDC); Otsuka Pharmaceutical, Co. Ltd. (Otsuka); and Visterra, Inc., an Otsuka group company announce that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for the investigational drug sibeprenlimab for the treatment of immunoglobulin A nephropathy (IgAN; Berger’s disease).

Key Points: 
  • Otsuka Pharmaceutical Development & Commercialization, Inc., (OPDC); Otsuka Pharmaceutical, Co. Ltd. (Otsuka); and Visterra, Inc., an Otsuka group company announce that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for the investigational drug sibeprenlimab for the treatment of immunoglobulin A nephropathy (IgAN; Berger’s disease).
  • This press release features multimedia.
  • Breakthrough therapy designation allows the agency to prioritize and focus resources on the most promising products for which no satisfactory treatment option exists.
  • “We are encouraged by the FDA’s decision to grant breakthrough therapy status for the sibeprenlimab program,” said John Kraus, M.D., Ph.D., executive vice president and chief medical officer at Otsuka.

5 Tell-Tale Signs Hard Water Is Affecting Your Home

Retrieved on: 
Thursday, February 15, 2024

Hard water contaminants can be removed by water softener systems like the Culligan Aquasential® Smart High Efficiency (HE) Water Softener which offers high-efficiency water softening for your home and is regarded as the world’s most efficient water softener**.

Key Points: 
  • Hard water contaminants can be removed by water softener systems like the Culligan Aquasential® Smart High Efficiency (HE) Water Softener which offers high-efficiency water softening for your home and is regarded as the world’s most efficient water softener**.
  • Here are five tell-tale signs that you may be dealing with hard water issues:
    Stains and Dullness of Clothing.
  • Dissolved calcium and magnesium salts in hard water can accumulate in appliances like dishwashers, washing machines, and water heaters, leading to decreased efficiency and potential damage.
  • Reduced water flow or pressure can be another indication, as hard water minerals accumulate and narrow the pipe's interior.

“The Weekly Check-Up Podcast” brings acclaimed healthcare talk radio show to larger audience

Retrieved on: 
Thursday, February 15, 2024

“Having produced more than a decade of ‘The Weekly Check-Up’ radio content, it's exciting to introduce a new platform to share the latest healthcare information with as many listeners as possible,” says host Dr. Bruce Feinberg.

Key Points: 
  • “Having produced more than a decade of ‘The Weekly Check-Up’ radio content, it's exciting to introduce a new platform to share the latest healthcare information with as many listeners as possible,” says host Dr. Bruce Feinberg.
  • Since the show began in 2011, Dr. Feinberg has amassed more than 500 hours of content featuring countless thought-provoking questions from listeners.
  • Dr. Feinberg will pair some of the most compelling content from the show’s archives with new, invaluable and practical answers and perspectives.
  • New episodes of “The Weekly Check-Up Podcast” will appear every other week on all major podcast platforms including Spotify, Apple Podcasts, and Google Podcasts.

Hearing loss company Acousia announces first patient enrolled in its Phase 2 PROHEAR-Study

Retrieved on: 
Thursday, February 15, 2024

TÜBINGEN, Germany, Feb. 15, 2024 /PRNewswire/ -- Acousia Therapeutics GmbH, a Tübingen-based clinical stage biotech company focused on the enhancement and preservation of natural hearing, just announced the randomization of the first patient for the PROHEAR-Study.

Key Points: 
  • TÜBINGEN, Germany, Feb. 15, 2024 /PRNewswire/ -- Acousia Therapeutics GmbH, a Tübingen-based clinical stage biotech company focused on the enhancement and preservation of natural hearing, just announced the randomization of the first patient for the PROHEAR-Study.
  • Germ-cell testicular cancer is the most common cancer among young men, with incidence rates continuously increasing.
  • In preclinical models, ACOU085 has demonstrated its significant potential to reduce cisplatin-induced hearing loss and preserve outer hair cells from ototoxicity.
  • "The enrollment of the first patient into our ACOU085 Clinical Phase 2 program marks a further major milestone in our efforts to finally make acute and subacute forms of hearing loss treatable" said Dr. Tim Bölke, CEO and CMO of Acousia Therapeutics.

Hearing loss company Acousia announces first patient enrolled in its Phase 2 PROHEAR-Study

Retrieved on: 
Thursday, February 15, 2024

TÜBINGEN, Germany, Feb. 15, 2024 /PRNewswire/ -- Acousia Therapeutics GmbH, a Tübingen-based clinical stage biotech company focused on the enhancement and preservation of natural hearing, just announced the randomization of the first patient for the PROHEAR-Study.

Key Points: 
  • TÜBINGEN, Germany, Feb. 15, 2024 /PRNewswire/ -- Acousia Therapeutics GmbH, a Tübingen-based clinical stage biotech company focused on the enhancement and preservation of natural hearing, just announced the randomization of the first patient for the PROHEAR-Study.
  • Germ-cell testicular cancer is the most common cancer among young men, with incidence rates continuously increasing.
  • In preclinical models, ACOU085 has demonstrated its significant potential to reduce cisplatin-induced hearing loss and preserve outer hair cells from ototoxicity.
  • "The enrollment of the first patient into our ACOU085 Clinical Phase 2 program marks a further major milestone in our efforts to finally make acute and subacute forms of hearing loss treatable" said Dr. Tim Bölke, CEO and CMO of Acousia Therapeutics.

Generation Z may not need mortgages, here’s why

Retrieved on: 
Wednesday, February 14, 2024

The idea of getting a mortgage with just their own income is often unthinkable, and those who do own property often have an uncommonly early inheritance to thank.

Key Points: 
  • The idea of getting a mortgage with just their own income is often unthinkable, and those who do own property often have an uncommonly early inheritance to thank.
  • While housing crises rage across Europe, many members of Generation Z – those born after the year 2000 – may soon find that the shoe is on the other foot.
  • Generation Z therefore stands to benefit from Europe’s declining birth rate, one of the lowest in the world at 1.53 children per woman.

Mortgages: an increasingly unattractive prospect

  • If you meet these criteria, you are then locked into, on average, a 25-year commitment.
  • The prospect of getting one is especially unappealing at a time when rising mortgage rates are driving the cost of living up in Europe and beyond.

Home ownership in Europe today

  • The average mortgage duration is 25 years, meaning payments are typically completed by the age of 59, just before retirement age (65 in most EU member states).
  • This does vary widely across the continent, and there is little correlation between ownership rates and the number of active mortgages.
  • In contrast, this percentage is far lower in countries like Italy, where only 14.6% of homeowners have a mortgage.

Spain: a case in point

  • It is above average in life expectancy and rates of home ownership (especially among older generations): the average Spaniard first purchases property at age 41, and receives an inheritance at 51.
  • From 2021 to 2022 the number of homes inherited in Spain rose by 3.7%, with over 17,800 homes inherited per month within its borders.

Leaving the family home

  • However, the value of inheritances varies widely across different countries and wealth distributions, and it is difficult to make predictions for all of Europe.
  • There is also huge variation in factors such as the age of leaving the family home.
  • In Finland, on the other hand, people typically leave home at age 21.4, with similarly low figures across Scandinavia.
  • Spain’s staggering drop of 62.54% in new mortgages from 2007 to 2023 is reflected in data from across Europe.

Impacts on Generation Z

  • Though they will face plenty of other problems, such as securing stable employment contracts, housing might not be the primary concern for much of Generation Z in the future.
  • This will benefit Millennials to a certain extent, but with fewer siblings, many wealthier members of Generation Z might not need to divide inheritances from parents who often own multiple properties.


Geoffrey Ditta no recibe salario, ni ejerce labores de consultoría, ni posee acciones, ni recibe financiación de ninguna compañía u organización que pueda obtener beneficio de este artículo, y ha declarado carecer de vínculos relevantes más allá del cargo académico citado.

Study Finds That Improving Financial Literacy Supports Retirement Wellness and Confidence

Retrieved on: 
Wednesday, February 14, 2024

KING OF PRUSSIA, Pa., Feb. 14, 2024 /PRNewswire/ -- The American College of Financial Services 2023 Retirement Income Literacy Study finds that older Americans lack actionable retirement knowledge—averaging 31% on a retirement literacy quiz. The study reinforces the direct relationships that exist between financial literacy and factors such as asset level, as respondents with more than $1.5 million score twice as high as those with less than $100,000 (50% vs. 25%). The study also reveals the essential role financial professionals play in educating clients, as advised respondents have higher retirement income literacy and better outcomes than their peers.

Key Points: 
  • The American College of Financial Services shares the fourth iteration of the Retirement Income Literacy Study to gauge older Americans' retirement knowledge, highlight gaps and opportunities
    KING OF PRUSSIA, Pa., Feb. 14, 2024 /PRNewswire/ -- The American College of Financial Services 2023 Retirement Income Literacy Study finds that older Americans lack actionable retirement knowledge—averaging 31% on a retirement literacy quiz.
  • The 2023 Retirement Income Literacy Study reveals the predicted probability of the highest Retirement Confidence level increases with Retirement Income Literacy Score.
  • "When we measured financial anxiety and financial stress, those with a financial professional had 20% less financial anxiety and 25% less financial stress."
  • The 2023 Retirement Income Literacy Study conducted by The American College of Financial Services measures financial literacy in 12 retirement-related knowledge areas among individuals approaching or in retirement age.

Biogen Received European Commission Approval for SKYCLARYS® (omaveloxolone), the First Therapy to Treat Friedreich’s Ataxia

Retrieved on: 
Monday, February 12, 2024

“Friedreich’s ataxia patients treated with SKYCLARYS in the clinical trial experienced important and clinically meaningful improvements for their daily lives.

Key Points: 
  • “Friedreich’s ataxia patients treated with SKYCLARYS in the clinical trial experienced important and clinically meaningful improvements for their daily lives.
  • At the end of the 48-week study, patients who received SKYCLARYS had significantly improved modified Friedreich Ataxia Rating Scale (mFARS) scores relative to placebo.
  • Biogen is committed to working closely with all stakeholders to ensure that eligible European patients can have access to this treatment.
  • SKYCLARYS is also approved for use in the United States, and Biogen is engaging with regulatory authorities in other regions.

Best Life Insurance Plans for Diabetics - Our Top Picks for 2024

Retrieved on: 
Monday, February 12, 2024

Continued Bland, "Our 50-insurer database is continually updated, which makes it a valuable resource for diabetics who are searching for the best buys in life insurance."

Key Points: 
  • Continued Bland, "Our 50-insurer database is continually updated, which makes it a valuable resource for diabetics who are searching for the best buys in life insurance."
  • Instant life insurance quotes for both type 1 and type 2 diabetics are available at www.lifequotes.com .
  • Life insurance policies described, quoted, shown and illustrated throughout this press release may not be available in all states.
  • Pacific Life Insurance Company of Newport Beach, CA, policy form P16LYT or ICC 16 P16LYT.

To make economic globalization more open, inclusive, balanced, beneficial to all

Retrieved on: 
Thursday, February 8, 2024

To grasp the development trend of economic globalization, it is important to start from the objective laws of historical development.

Key Points: 
  • To grasp the development trend of economic globalization, it is important to start from the objective laws of historical development.
  • The deepening development of economic globalization has provided a powerful impetus for the progress of human society.
  • Economic globalization should be beneficial to all, aligning with the universal aspirations of countries around the world, especially developing ones.
  • Looking ahead, economic globalization remains an inevitable path forward and an irreversible trend of the times for human society.