Marc

Hilco Global Warms the Winter by Providing Coats to Asylum Seekers and the Homeless

Retrieved on: 
Wednesday, December 20, 2023

CHICAGO, Dec. 20, 2023 /PRNewswire/ -- Hilco Global, a prominent B2B financial services company is committed to giving back to communities where it does business by donating time, money and in-kind goods. "Hilco Helps Warm the Winter" initiative is designed to deliver assistance to local communities in need by providing basic cold-weather essentials including brand new winter coats, hats, gloves, scarves, etc. As the winter season unfolds, Hilco Global recognizes the heightened vulnerability of our neighboring communities, including the thousands of asylum seekers that have been flooding cold weather communities like Chicago, Boston, Philadelphia, etc.

Key Points: 
  • "Hilco Helps Warm the Winter" initiative is designed to deliver assistance to local communities in need by providing basic cold-weather essentials including brand new winter coats, hats, gloves, scarves, etc.
  • As the winter season unfolds, Hilco Global recognizes the heightened vulnerability of our neighboring communities, including the thousands of asylum seekers that have been flooding cold weather communities like Chicago, Boston, Philadelphia, etc.
  • This year, Hilco Global joined forces with the Marc and Jeanne Malnati Family Foundation to donate coats to offer warmth and comfort to asylum seekers facing the challenges of winter without adequate resources.
  • Hilco Redevelopment Partners (HRP), an operating company of Hilco Global, is also donating over 3000 coats in cities across the US.

Noetik Launches "Perturb-map" In Vivo Functional Genomics Platform and Adds Precision Immunology Leader Brian Brown, Ph.D. to Scientific Advisory Board

Retrieved on: 
Wednesday, November 15, 2023

The platform builds on Perturb-map, a groundbreaking spatial functional genomics technology that allows pooled parallel analysis of hundreds of genetically modified tumor clones in a single experiment.

Key Points: 
  • The platform builds on Perturb-map, a groundbreaking spatial functional genomics technology that allows pooled parallel analysis of hundreds of genetically modified tumor clones in a single experiment.
  • Noetik’s platform will evaluate the impact of genetic variants at an unprecedented in vivo scale.
  • The company is currently generating an initial dataset of >650 mutations in a preclinical model of lung cancer, including pharmacological perturbations.
  • Jacob Rinaldi, Ph.D, CSO & Co-Founder, Noetik emphasized: “Existing preclinical models poorly replicate human cancer biology, and cannot reveal more complex phenotypes at scale.

A Type of Allergy Medicine Might Help Treat Lung Cancer, Research Suggests

Retrieved on: 
Wednesday, December 6, 2023

NEW YORK, Dec. 6, 2023 /PRNewswire-PRWeb/ -- Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

Key Points: 
  • Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).
  • NEW YORK, Dec. 6, 2023 /PRNewswire-PRWeb/ -- Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).
  • "Strikingly, we found that IL-4 blockade enhanced lung cancer response to checkpoint blockade in mice and in six lung cancer patients with treatment-resistant disease.
  • "In our relentless pursuit of progress, the Cancer Research Institute (CRI) proudly supports the visionary team at the Icahn School of Medicine at Mount Sinai.

Mount Sinai Researchers Receive $7 Million to Improve Outcomes for High-risk Blood Cancer Patients From the Multiple Myeloma Research Foundation

Retrieved on: 
Thursday, November 2, 2023

NEW YORK, Nov. 2, 2023 /PRNewswire-PRWeb/ -- The Mount Sinai Health System has received a $7 million grant from the Multiple Myeloma Research Foundation for a three-year project that aims to fast-track novel translational concepts to improve outcomes for people with high risk myeloma, the second most common blood cancer in the United States.

Key Points: 
  • Multiple myeloma is a blood cancer that develops in the bone marrow and can spread throughout the body.
  • In 2023, more than 35,000 Americans are projected to be diagnosed with multiple myeloma and approximately 12,000 will lose their lives.
  • Researchers hope to uncover the full landscape of genomic, proteomic and immune differences between high- and standard-risk multiple myeloma patients.
  • "The three exciting programs we selected each have potential to answer fundamental questions about multiple myeloma and help advance rational treatments for this cancer."

Miriam Merad, MD, PhD, Elected to the National Academy of Medicine for Seminal Work in Immunology and Cell Biology

Retrieved on: 
Monday, October 9, 2023

NEW YORK, Oct. 9, 2023 /PRNewswire-PRWeb/ -- Miriam Merad, MD, PhD, an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology.

Key Points: 
  • Miriam Merad, MD, PhD, an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology.
  • NEW YORK, Oct. 9, 2023 /PRNewswire-PRWeb/ -- Miriam Merad, MD, PhD, an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology.
  • With this appointment, Dr. Merad joins an elite group of distinguished international scientists alongside 100 new members this year.
  • For more details, see this year's official announcement from the National Academy of Medicine: https://nam.edu/news/ .

New RNA-based Therapy Combats Melanoma in Mouse Models; Experimental approach that triggers a type of immune cell may be beneficial against cancers in humans

Retrieved on: 
Thursday, July 27, 2023

NEW YORK, July 27, 2023 /PRNewswire-PRWeb/ -- Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells—which play a key role in immune response—that eradicated tumors and prevented their recurrence in mouse models of melanoma.

Key Points: 
  • Cancer cells employ strategies to switch off various stages of the cancer-immunity cycle, the process by which dendritic cells educate T cells to kill cancer cells.
  • Their investigations revealed encouraging results, as the regimen reduced tumors in mouse models of B cell lymphoma by 83 percent.
  • They also tested it in mouse models of breast cancer, where approximately half of the mice favorably responded.
  • The study was funded in part by National Cancer Institute grant P30 CA016058 and National Institute of General Medical Sciences grant R35GM144117.

Record-breaking 53 Emergency Departments Receive ENA Lantern Award

Retrieved on: 
Wednesday, July 12, 2023

SCHAUMBURG, Ill., July 12, 2023 /PRNewswire/ -- The 2023 class of ENA Lantern Award recipients is the largest since the award was established in 2011, with a total of 53 emergency departments around the world receiving the honor.

Key Points: 
  • The ENA Lantern Award was created to recognize emergency departments demonstrating exceptional and innovative leadership, practice, education, advocacy and research performance.
  • Nebraska is also boasting its first Lantern Award recipient with the Children's Hospital & Medical Center Emergency Department in Omaha.
  • Other hospitals in the TriHealth Healthcare System include Bethesda Arrow Springs Emergency Department (2020), Good Samaritan Medical Center Western Ridge ED (2020), Bethesda Butler Hospital Emergency Department (2021), Bethesda North Hospital Emergency Department (2022), Good Samaritan Hospital Emergency Department (2022).
  • The 2023 ENA Lantern Award recipients are:
    Advocate Sherman Hospital Emergency Department – Elgin, Illinois
    Atrium Health Carolinas Medical Center Adult Emergency Department – Charlotte, North Carolina
    Baptist Hospital of Miami Emergency Department – Miami, Florida
    Bayshore Medical Center, Dr. Robert H. Harris Emergency Care Center – Holmdel, New Jersey
    Bethesda Arrow Springs Emergency Department – Lebanon, Ohio
    Cape Coral Hospital Emergency Department – Cape Coral, Florida
    CentraState Medical Center Emergency Department – Freehold, New Jersey
    Children's Hospital & Medical Center Emergency Department – Omaha, Nebraska
    CHOC Children's Hospital - Julia and George Argyros Emergency Department – Orange, California
    ChristianaCare Wilmington Hospital Emergency Department – Wilmington, Delaware
    CHRISTUS Children's Hospital Emergency Department – San Antonio, Texas
    Cleveland Clinic Abu Dhabi, Emergency Department – Abu Dhabi, United Arab Emirates
    Cleveland Clinic Marymount Hospital Emergency Department – Garfield Heights, Ohio
    Cleveland Clinic Weston Hospital Emergency Department – Weston, Florida
    El Camino Health, Mountain View Emergency Department – Mountain View, California
    Froedtert Hospital Emergency Department – Milwaukee, Wisconsin
    Glen Cove Hospital Emergency Department – Glen Cove, New York
    Good Samaritan Hospital, Western Ridge Emergency Department – Cincinnati, Ohio
    Gundersen Health System Emergency Services – La Crosse, Wisconsin
    HCA Florida Capital Hospital Emergency Department – Main – Tallahassee, Florida
    Intermountain Medical Center Emergency Department – Murray, Utah
    Mary Imogene Bassett Hospital Emergency Department – Cooperstown, New York
    McCullough-Hyde Memorial Hospital Emergency Department – TriHealth – Oxford, Ohio
    MetroHealth Medical Center Main Campus Emergency Department – Cleveland, Ohio
    Morristown Medical Center, Sameth Emergency Department – Morristown, New Jersey
    Nicklaus Children's Hospital Emergency Department – Miami, Florida
    Northeast Georgia Medical Center - Barrow Emergency Department – Winder, Georgia
    Northeast Georgia Medical Center - Gainesville Emergency Department – Gainesville, Georgia
    Northwestern Medicine Central DuPage Hospital Emergency Department – Winfield, Illinois
    NYC Health + Hospitals/South Brooklyn Health Emergency Department – Brooklyn, New York
    NYU Langone Hospital, Brooklyn Emergency Department – Brooklyn, New York
    Old Bridge Medical Center Emergency Department – Old Bridge, New Jersey
    Orlando Health South Seminole Hospital Emergency Department – Longwood, Florida
    Overlook Medical Center Emergency Services, Union Campus, Atlantic Health System – Union, New Jersey
    Palomar Medical Center Escondido Emergency Department – Escondido, California
    Piedmont Rockdale Hospital Emergency Department – Conyers, Georgia
    Raritan Bay Medical Center Emergency Department – Perth Amboy, New Jersey
    Rose Medical Center Emergency Department – Denver, Colorado
    Rush University Medical Center Emergency Department – Chicago, Illinois
    Sharp Grossmont Hospital Emergency Department – La Mesa, California
    Sharp Memorial Hospital Emergency Department – San Diego, California
    St. Elizabeth Healthcare Grant County Emergency Department – Williamstown, Kentucky
    Stanford Health Care - The Marc and Laura Andreessen Emergency Department – Stanford, California
    The Christ Hospital Medical Center Emergency Department-Liberty Township – Liberty Township, Ohio
    The Hospital of the University of Pennsylvania Emergency Department – Penn Medicine – Philadelphia, Pennsylvania
    The Mount Sinai Hospital Emergency Department – New York, New York
    UCLA Santa Monica Nethercutt Emergency Medical Center – Santa Monica, California
    Vail Health Hospital Emergency Department – Vail, Colorado
    Washington Regional Medical Center Emergency Department – Fayetteville, AR
    White Plains Hospital Emergency Department – White Plains, New York
    The 2023 ENA Lantern Award recipients will receive a physical award to display in their emergency department as a visible symbol of their commitment to quality, safety and a healthy work environment.

Stanford University’s Innovative Medicines Accelerator and Intonation Research Laboratories (Intonation) form a collaboration to fight cancerous neuroendocrine tumors

Retrieved on: 
Thursday, June 22, 2023

Stanford University’s Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories (Intonation) have formed a collaboration to develop treatments that target cancerous neuroendocrine tumors, or tumors that form from hormone-releasing cells.

Key Points: 
  • Stanford University’s Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories (Intonation) have formed a collaboration to develop treatments that target cancerous neuroendocrine tumors, or tumors that form from hormone-releasing cells.
  • “I’m excited about this collaboration with Intonation Research Laboratories, which has the potential to speed the translation of promising research into urgently needed new treatments and therapies,” said Marc Tessier-Lavigne , president of Stanford University.
  • “We hope to greatly accelerate our drug development program and deliver transformative treatments to patients burdened with neuroendocrine tumors,” he said.
  • “The IMA continues to seek high-quality partners in our mission as an accelerator,” said Khosla, the Marc and Jennifer Lipschultz Director of the Stanford Innovative Medicines Accelerator.

Save-A-Lot and Food 4 Less are Top Retailers for SNAP Customers, dunnhumby Finds

Retrieved on: 
Monday, May 22, 2023

CHICAGO, May 22, 2023 /PRNewswire-PRWeb/ -- dunnhumby, the global leader in customer data science, today released a special report examining which U.S. grocery retailers are best positioned to win the loyalty of current and potential Supplemental Nutrition Assistance Program (SNAP) recipients and how retailers can limit grocery sales losses due to recently enacted SNAP reductions. The SNAP Rollercoaster: A dunnhumby Special Report on Hunger in the U.S. ranked Save-A-Lot, Food 4 Less, and Dollar General as the top three grocery retailers for SNAP customers with Winco and Grocery Outlet rounding out the top five. The next five retailers in the top ten are Price Rite (6), Walmart (7), Aldi (8), Marcs (9) and H-E-B (10).

Key Points: 
  • The SNAP Rollercoaster: A dunnhumby Special Report on Hunger in the U.S. ranked Save-A-Lot, Food 4 Less, and Dollar General as the top three grocery retailers for SNAP customers with Winco and Grocery Outlet rounding out the top five.
  • Cashiers and food service workers are twice as likely as the general population to be on SNAP.
  • Retailers should look at SNAP and food insecure customers as a segment to target with actions that appeal to them.
  • However, retailers can serve the SNAP and food insecure customer by more thinly slicing their price sensitivity segmentations.

Mechanisms Underlying Autoimmunity in Down Syndrome Revealed

Retrieved on: 
Wednesday, February 22, 2023

NEW YORK, Feb. 22, 2023 /PRNewswire-PRWeb/ -- Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature [DOI: https://doi.org/10.1038/s41586-023-05736-y .

Key Points: 
  • Studying lab specimens from volunteers with Down syndrome, the investigators identified cytokines and a B cell subtype—key players in the adaptive immune response—as the potential culprits for most autoimmunity in people with the disorder.
  • Strikingly, the researchers found that many people with Down syndrome are in a perpetual state of inflammation comparable to those without Down syndrome who are in intensive care with an acute infection.
  • Among other issues, people with Down syndrome suffer from autoimmunity, including hair loss, skin, gut, and thyroid problems.
  • The paper is titled "Autoimmunity in Down syndrome via cytokines, CD4 T Cells, and CD11c + B cells."