LPS

Edgewood Oncology Announces Positive Efficacy Data From Investigator-Sponsored Study of BTX-A51 in Preclinical Models of Liposarcoma

Retrieved on: 
Sunday, April 7, 2024
Health, General Health, Research, Pharmaceutical, Science, Biotechnology, Bone marrow, CDK7, MDM2, Apoptosis, BH3, CDK, AML, Dana–Farber Cancer Institute, Patient, LPS, Neoplasm, DNA, Cancer, Liposarcoma, Clinical trial, Azacitidine, CDK9, MCL1, Vaccine

The presentation (Abstract 604), “Targeting casein kinase 1 alpha (CK1alpha) and transcriptional CDKs (CDK7/9) in human liposarcomas,” highlighted findings for BTX-A51 in preclinical human models of LPS.

Key Points: 
  • The presentation (Abstract 604), “Targeting casein kinase 1 alpha (CK1alpha) and transcriptional CDKs (CDK7/9) in human liposarcomas,” highlighted findings for BTX-A51 in preclinical human models of LPS.
  • The data demonstrate that BTX-A51 has preclinical efficacy in treating patient-derived LPS in cell lines and human xenograft models and provides insight into the synergy gained by inhibiting both CK1α and CDK9.
  • “Dedifferentiated liposarcomas (DDLPS) are rare tumors derived from precursors of fat cells which can occur anywhere in the body.
  • Importantly, preliminary in vivo data in an LPS patient-derived xenograft model reveal that BTX-A51 is well-tolerated under conditions that inhibit tumor growth.

Topcon Announces MC-Max Asphalt Paving and Milling Solutions

Retrieved on: 
Tuesday, March 26, 2024
Technology, Engineering, Robotics, Manufacturing, Other Transport, Other Construction & Property, Machinery, Construction & Property, Transport, Other Technology, Software, Hardware, Other Manufacturing, Satellite, DOT, Asphalt, LPS, 3D, Miller, Architecture, OEM, Multimedia, Road, GNSS

Topcon Positioning Systems has announced the latest evolution of the company’s road construction and resurfacing technology with the introduction of the MC-Max Asphalt Paving and MC-Max Milling solutions.

Key Points: 
  • Topcon Positioning Systems has announced the latest evolution of the company’s road construction and resurfacing technology with the introduction of the MC-Max Asphalt Paving and MC-Max Milling solutions.
  • The systems offer modularity, simplified configurations and advanced feature sets to increase productivity in asphalt paving and cold milling applications for construction companies and projects of all sizes.
  • View the full release here: https://www.businesswire.com/news/home/20240326958469/en/
    Topcon announces expansions to its intelligent paving portfolio.
  • The new solutions were announced at World of Asphalt 2024 in Nashville.

GCANRx Announces Completion of Preclinical Study for Neuropsychiatric Cannabinoid Therapy

Retrieved on: 
Tuesday, February 27, 2024
Therapy, Reactive oxygen species, Alzheimer's disease, MicroRNA, Inflammation, OTC, LPS, Schizophrenia, Nitric oxide, Cell, Factorization of polynomials, Safety, Protein, Clinical trial, Gene, DSM-IV codes, ROS, Hebrew University of Jerusalem, Microglia, Anoxic waters, Spectrum, Al-Quds, Research, Cannabidiol, Pharmaceutical industry

Professor Tal Burstyn-Cohen, Ph.D. of the Hebrew University, through the Yissum Research Development Company, led the preclinical study.

Key Points: 
  • Professor Tal Burstyn-Cohen, Ph.D. of the Hebrew University, through the Yissum Research Development Company, led the preclinical study.
  • The preclinical study aimed to assess the impact of various combinations of the neuroprotective therapeutic in a preclinical model.
  • “We are excited to finally receive the positive results from our preclinical study, which was our first step in validating our novel, cannabinoid based therapeutic,” said Aitan Zacharin, GCANRx CEO.
  • To receive the latest information about GCANRx sign up to the investor email at https://bit.ly/2ZNlBoj or follow @GCANRX on Twitter.

LITTLEST PET SHOP Experience on Roblox Smashes Expectations with Over 2 Million Visits in First Month

Retrieved on: 
Thursday, January 25, 2024
Senior, Social media, IBM Series/1, Collection, LPS, Adventure, History, Pet, Communication, Environment, Digital, Creativity, BOCA, Toy

In anticipation of its retail debut, LITTLEST PET SHOP is already enchanting fans with over 2 million unique visits of the brand's new digital experience on the global immersive platform for communication and connection, Roblox.

Key Points: 
  • In anticipation of its retail debut, LITTLEST PET SHOP is already enchanting fans with over 2 million unique visits of the brand's new digital experience on the global immersive platform for communication and connection, Roblox.
  • The LITTLEST PET SHOP Roblox experience introduces a host of interactive features, allowing users to care for, customize, and embark on adventures with their favorite bobblin' pets.
  • Fans of LITTLEST PET SHOP have flooded social media platforms with positive reviews, sharing their excitement and experiences within the virtual space.
  • Starting with a December presale that sold out within days, the LITTLEST PET SHOP Generation 7 toy line from Basic Fun!

Athira Pharma Presents Preclinical Data Highlighting Fosgonimeton’s Neuroprotective Effects Against Amyloid-β-Induced Pathological Alterations and Neuroinflammation in Models of Alzheimer’s Disease

Retrieved on: 
Wednesday, November 15, 2023
Molecule, ISCB Senior Scientist Award, Annual general meeting, HGF, Cell proliferation, Athira Pharma, Neuron, Microglia, LPS, Oxidative stress, Neurogenesis, Neuroinflammation, Society, Pharmaceutical industry, Medical imaging, Neuroscience, Neurotrophic factors

“We continue to build the body of preclinical evidence supporting the continued development of fosgonimeton to treat AD and other debilitating neurodegenerative diseases,” said Kevin Church, Ph.D., Chief Scientific Officer, Athira Pharma.

Key Points: 
  • “We continue to build the body of preclinical evidence supporting the continued development of fosgonimeton to treat AD and other debilitating neurodegenerative diseases,” said Kevin Church, Ph.D., Chief Scientific Officer, Athira Pharma.
  • “Our latest data demonstrate consistent neuroprotective effects of fosgonimeton and provide insights into the mechanisms by which it preserves neurons from degeneration and reduces neuroinflammation.
  • Wei Wu, Ph.D., Senior Scientist II, Athira Pharma, presented preclinical research demonstrating the cellular mechanisms by which fosgonimeton induces anti-inflammatory effects in BV2 microglia cells.
  • The anti-inflammatory effects of fosgonimeton demonstrated in these models suggest it may have the potential to help reduce neuroinflammation, a key pathological feature of several neurodegenerative diseases.

DAMAC PROPERTIES LAUNCHES NEW SALES OFFICE IN CHINA

Retrieved on: 
Wednesday, December 13, 2023
DAMAC Tower Nine Elms, HNWI, Dubai Canal, Versace, DAMAC Properties, Shanghai Exhibition Centre, LPS, DAMAC, UHNWI, Exhibition, Drug

DAMAC Properties also participated in Shanghai's Luxury Property Show in 2023, Asia-Pacific's leading luxury real estate exhibition.

Key Points: 
  • DAMAC Properties also participated in Shanghai's Luxury Property Show in 2023, Asia-Pacific's leading luxury real estate exhibition.
  • DUBAI, UAE, Dec. 13, 2023 /PRNewswire/ -- Leading UAE-based real estate developer DAMAC Properties has announced the opening of its latest international sales centre in Shanghai, China on 12 December, 2023.
  • The new DAMAC Properties sales office in Shanghai comes in light of growing demand from China which notably, according to a recent real estate report, re-entered the Dubai property market in the second quarter of 2023.
  • Commenting on the new sales centre, Hussain Sajwani, Founder and Chairman of DAMAC Properties said, "This new chapter in our global story is a testament to DAMAC Properties' commitment to international excellence.

Global Lightning Protection Technology (LPT) Industry Report 2023-2030: Growth in Smart Home Numbers Drive the Need for Lightning Protection Solutions

Retrieved on: 
Monday, December 11, 2023
Calamity, LPT, Static electricity, World population, Growth, Convention (norm), Uncertainty, Building, LPS, Urbanization, Urban area, Electricity, Risk management, Coal, Agriculture, Causality, Lightning

DUBLIN, Dec. 11, 2023 /PRNewswire/ -- The "Lightning Protection Technologies (LPT) - Global Strategic Business Report" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • DUBLIN, Dec. 11, 2023 /PRNewswire/ -- The "Lightning Protection Technologies (LPT) - Global Strategic Business Report" report has been added to ResearchAndMarkets.com's offering.
  • Lightning protection technologies (LPT) are essential systems designed to mitigate and manage the risks associated with lightning strikes.
  • It explores the growth drivers and challenges facing the global lightning protection technologies market.
  • The market for lightning protection systems is expected to exhibit long-term growth, driven by the pressing need to mitigate and manage the risks of lightning strikes.

Amerigo Announces Q3-2023 Results & Quarterly Dividend

Retrieved on: 
Wednesday, November 1, 2023
Amerigo, London Metal Exchange, MVC, Molybdenum, Copper, Conference, LPS, Transport, DET, Cryptocurrency

VANCOUVER, British Columbia, Nov. 01, 2023 (GLOBE NEWSWIRE) -- Amerigo Resources Ltd. (TSX: ARG; OTCQX: ARREF) (“Amerigo” or the “Company”) announces financial results for the three months ended September 30, 2023 (“Q3-2023”). Dollar amounts in this news release are in U.S. dollars unless indicated otherwise.

Key Points: 
  • Tolling and production costs were $32.4 million (Q3-2022: $34.4 million) due to lower copper production.
  • MVC’s molybdenum price increased to $23.31/lb (Q3-2022: $15.39/lb), resulting in a Q3-2023 molybdenum revenue of $4.6 million (Q3-2022: $3.5 million).
  • In Q3-2023, Amerigo returned $3.7 million to shareholders (Q3-2022: $3.8 million) through Amerigo’s quarterly dividend of Cdn$0.03 per share.
  • Dial 1-888-664-6392 (Toll-Free North America) and state they wish to participate in the Amerigo Resources Q3-2023 Earnings Call.

THE FUTURE OF IMMERSIVE ENTERTAINMENT IS NOW - THE SPHERE EXPERIENCE PREMIERES TOMORROW

Retrieved on: 
Thursday, October 5, 2023
Academy Awards, Sport, NYSE, ASC, 3D, Machine learning, Music, Eye, Culture, Portrait, LED, Artificial intelligence, Creativity, Postcard, SPHR, Longevity, History, Science, Howe, LPS, ACE, Tourism, Entertainment, Film industry, Atrium, Sphere

LAS VEGAS, Oct. 5, 2023 /PRNewswire/ -- Sphere Entertainment Co. (NYSE: SPHR) will tomorrow debut The Sphere Experience, a signature content category featured at Sphere – the next-generation entertainment medium that opened in Las Vegas last week, capturing worldwide attention for its stunning visual displays and immersive technologies. 

Key Points: 
  • The Sphere Experience is a new genre of live entertainment that will transform the shared experience and put Sphere's 22nd century immersive technologies on full display.
  • Through one-of-a-kind immersive experiences created specifically for Sphere, guests will gain a better understanding of how technology amplifies our human potential.
  • The Sphere Experience then continues in the main venue bowl for a muti-sensory cinematic experience at an unparalleled scale – Darren Aronofsky's Postcard from Earth.
  • "Every aspect of Sphere was designed to transport audiences to new places, both real and imagined, and The Sphere Experience is where that vision comes together in its most integrated form," said James L. Dolan, Executive Chairman and CEO of Sphere Entertainment.

LITTLEST PET SHOP Kicks Off Massive Global Relaunch with New Experience on Roblox

Retrieved on: 
Thursday, September 28, 2023
Heart, Digital, DNA, Communication, Partnership, Littlest Pet Shop (video game), Senior, Friends, BOCA, LPS, History, Market, Pet, Social media, Toy, Hasbro, Roblox

BOCA RATON, Fla., Sept. 28, 2023 /PRNewswire/ -- LITTLEST PET SHOP, one of the most well-known collectible toy brands in history, will be marking its long-anticipated return to retail with an immersive digital play experience on the global immersive platform for communication and connection. The brand-new pet simulation experience, which will launch worldwide in December 2023, is a joint collaboration between LITTLEST PET SHOP Master Toy licensee, Basic Fun!, a leading global marketer of toys and consumer products, Hasbro, Inc. (NASDAQ: HAS), a leading toy and game company, and Suit Up Games, a Roblox development studio specializing in high-engagement branded experiences for young audiences.

Key Points: 
  • "We are thrilled to partner with Suit Up Games and Hasbro to bring LITTLEST PET SHOP to Roblox," said Maureen Dilger, Vice President of Global Brand Marketing of Basic Fun!
  • "There has been a gap in the Roblox marketplace for a pet simulation game leveraging the pet collector genre.
  • "In reimagining LITTLEST PET SHOP for a modern audience, it was clear that we needed to meet today's kids and kidults where they are.
  • The December 2023 release of the experience will kickstart a global marketing campaign to relaunch LITTLEST PET SHOP to fans and collectors around the world.