Sodium

Compilation of quality review of documents (QRD) on stylistic matters in product information

Retrieved on: 
Sunday, March 10, 2024

29 February 2024

Key Points: 
    • 29 February 2024
      EMA/25090/2002 rev.23*
      Human Medicines Division

      Compilation of QRD decisions on stylistic matters in product information
      Issues
      Abbreviations

      Connected problems
      Subscript and superscript

      QRD Suggestions
      Acronyms must be written in their standard form; e.g.

    • Cmax, Cmax
      Abbreviations and

      Not always understood,

      Non-standard abbreviations and acronyms should be avoided, and the term should be written out in full.

    • The same applies when stating the pharmaceutical form in section 3 of the SmPC and section 4 of the labelling;
      i.e.
    • critical steps prior to administration of the product should also be included (section 5 of Annex IIIA).
    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 2/23

      Issues

      Connected problems

      QRD Suggestions

      emphasise in the labelling
      the special handling prior
      to administration of the
      product.

    • Consistency

      Inconsistencies in style are

      Once a particular style or house style has been selected, it must be used consistently throughout the text.

    • Tradename 150 mg solution for injection in pre-filled syringe
      Tradename 150 mg solution for injection in pre-filled pen

      information annexes?

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 3/23

      Issues
      Desiccant

      Connected problems

      QRD Suggestions

      For medicinal products

      The foil of blister packs containing a desiccant must be clearly labelled to show which blister pocket contains

      packaged with a desiccant

      the desiccant.

    • For bottles containing a desiccant, a similar statement should also be considered provided there

      mistake the desiccant for a

      is available space.

    • It can only be included in brackets in section 3 of the

      where can this be

      SmPC and section 4 of the labelling.

    • Direct speech should only
      be used in section 6 of the SmPC for instructions about shelf-life, storage, handling and disposal.
    • The term ?drug? though can be used in the product information annexes when it is part of a standard set of
      terms (e.g.
    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 5/23

      Issues
      Foreign terms

      Connected problems

      QRD Suggestions

      Foreign terms, particularly

      Foreign terms must be written in italics; e.g.

    • Patients can be referred to as ?he? or

      physician is often referred

      as ?she? when the medicinal product is exclusively for use by males or females.

    • if the product in question might be

      measurements are

      used by elderly patients), in brackets after the metric measures in the English text.

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 6/23

      Issues

      Connected problems

      QRD Suggestions

      product name is composed
      of MAH+INN?

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 7/23

      Issues

      Connected problems

      QRD Suggestions
      MT: English
      BG: Bulgarian
      NL: Dutch
      CZ: Czech or English at applicant?s discretion.

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 14/23

      Issues

      Connected problems

      QRD Suggestions
      considered, e.g.

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 16/23

      Issues
      Symbols: Non-Unicode

      Connected problems

      QRD Suggestions

      The use of non-Unicode

      Only Unicode symbols must be used in submitted product information annexes.

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 20/23

      Issues

      Connected problems

      Units: SI base units -

      International Standard

      litre

      base units have been
      introduced in the European
      Union with Council
      Directive 80/181/EEC of
      20.12.79 (O.J.

    • Compilation of QRD decisions on stylistic matters in product information
      EMA/25090/2002

      Page 23/23

Site Survey Confirms Sodium Carbonate Potential at Laguna Santa Maria

Retrieved on: 
Friday, March 1, 2024

Soda ash is a critical reagent required to produce lithium carbonate; each tonne of lithium carbonate produced utilizes two tonnes of soda ash in processing.

Key Points: 
  • Soda ash is a critical reagent required to produce lithium carbonate; each tonne of lithium carbonate produced utilizes two tonnes of soda ash in processing.
  • Currently, much of the soda ash supply for the production of lithium carbonate in Argentina is sourced outside the country.
  • The 260 hectare Laguna Santa Maria appears as a salar or salt flat.
  • Work to date has included a Vertical Survey and a site visit with limited sampling.

Inlyte Energy welcomes Ben Kaun as its new Chief Commercial Officer

Retrieved on: 
Wednesday, February 28, 2024

SAN LEANDRO, Calif., Feb. 28, 2024 /PRNewswire/ -- Inlyte Energy , developer of iron + sodium grid batteries for a safe, responsible, and affordable renewable energy transition, warmly welcomes industry veteran Ben Kaun as its new Chief Commercial Officer (CCO).

Key Points: 
  • SAN LEANDRO, Calif., Feb. 28, 2024 /PRNewswire/ -- Inlyte Energy , developer of iron + sodium grid batteries for a safe, responsible, and affordable renewable energy transition, warmly welcomes industry veteran Ben Kaun as its new Chief Commercial Officer (CCO).
  • This addition is a signal of Inlyte's commercial readiness and commitment to address the world's rapidly growing stationary storage needs.
  • As CCO, Ben will shape Inlyte's go-to-market strategy, leveraging the company's unique technology to meet the needs of utilities and industrial customers.
  • Inlyte's iron + sodium battery is a workhorse technology with safety, reliability, and performance in long duration, daily cycling applications," Mr. Kaun stated.

Nona Lim Unveils Instant Noodle Bowls And Heat & Serve Entrees, Marking A Decade Of Authentic Asian Culinary Excellence

Retrieved on: 
Wednesday, February 21, 2024

OAKLAND, Calif., Feb. 21, 2024 /PRNewswire/ -- Nona Lim, the authentic Asian brand offering comfort, vitality and creativity in every bite, proudly commemorates a decade of connecting cultures through wholesome, flavorful cuisine. In 2014, Nona Lim embarked on a quest to introduce clean-label, tasty Asian flavors through their small-batch, slow-simmered bone broths. Founder Nona Lim was inspired by the rich hawker culture of her childhood in Singapore, a melting pot of pan-Asian flavors, aromas and cultures.

Key Points: 
  • In 2014, Nona Lim embarked on a quest to introduce clean-label, tasty Asian flavors through their small-batch, slow-simmered bone broths.
  • In addition to their original slow-simmered bone broth, the Nona Lim lineup now includes soups, fresh noodles, stir-fry kits and the latest Instant Noodle Bowls and Heat & Serve Meat Entrees.
  • "Marking a decade of Nona Lim is truly exhilarating," said founder Nona Lim.
  • Nona Lim's Instant Noodle Bowls (SRP $5.99) represent a groundbreaking innovation in the instant noodle category.

Electrolit Accelerates Performance as the Official 2024 Hydration Partner of Mexican Racing Driver Sergio "Checo" Pérez

Retrieved on: 
Tuesday, February 20, 2024

HOUSTON, Feb. 20, 2024 /PRNewswire/ -- In an exciting development for the world of racing, Electrolit proudly announces its collaboration with renowned Mexican racing driver Sergio Checo Pérez. Electrolit, the preferred premium hydration beverage made from pharmaceutical quality grade ingredients, is set to become the official hydration partner of Pérez for the 2024 season.

Key Points: 
  • HOUSTON, Feb. 20, 2024 /PRNewswire/ -- In an exciting development for the world of racing, Electrolit proudly announces its collaboration with renowned Mexican racing driver Sergio Checo Pérez.
  • Electrolit, the preferred premium hydration beverage made from pharmaceutical quality grade ingredients, is set to become the official hydration partner of Pérez for the 2024 season.
  • "I am thrilled to partner with Electrolit as my official hydration partner for the upcoming season," explained Pérez.
  • Let the 2024 season be a testament to the power of precision, performance and unbeatable hydration with Electrolit."

New FMI Report: Food Industry Committed to Health and Well-Being Initiatives

Retrieved on: 
Thursday, February 15, 2024

As Americans’ interest in nutrition and healthy eating has increased in recent years, companies across the food industry have implemented numerous initiatives to support consumers’ health needs and priorities, according to FMI – The Food Industry Association’s new Food Industry Contributions to Health and Well-Being 2024 report.

Key Points: 
  • As Americans’ interest in nutrition and healthy eating has increased in recent years, companies across the food industry have implemented numerous initiatives to support consumers’ health needs and priorities, according to FMI – The Food Industry Association’s new Food Industry Contributions to Health and Well-Being 2024 report.
  • While health and well-being has always been a key priority, nutrition and overall health has become the top focus for the food industry this year.
  • Food as Medicine programs that connect the science of food and nutrition to improved health for customers, employees and communities, are also gaining momentum across the food industry.
  • Members of the media may contact FMI for a gratis copy of the Food Industry Contributions to Health and Well-Being 2024 report.

Why ban ham from school canteens? And what are some healthier alternatives for kids’ lunches?

Retrieved on: 
Tuesday, February 13, 2024

Western Australia has introduced a limit on ham in school canteens. Parents are reportedly confused and frustrated. So what has changed and what evidence is it based on? Reclassifying processed meatsHam and other processed red meats have been moved from an “amber” label to a “red” label.

Key Points: 


Western Australia has introduced a limit on ham in school canteens. Parents are reportedly confused and frustrated. So what has changed and what evidence is it based on?

Reclassifying processed meats

  • Ham and other processed red meats have been moved from an “amber” label to a “red” label.
  • Read more:
    Yes, we still need to cut down on red and processed meat

    Each colour is associated with restrictions on how food and drinks can be sold:


There’s one catch. The new guidelines allow ham to be sold as if it is an amber item, only two days per week, if ham was already on a canteen’s menu prior to the reconfiguration.

Why restrict ham?

  • Rather than focusing on individual foods, long-term health outcomes are more closely linked to overall dietary patterns.
  • Saturated fat While ham is a good source of protein, certain cuts can be higher in saturated fat.
  • Processing methods The methods to process and cure ham may involve smoking, which can produce compounds such as polycyclic aromatic hydrocarbons.
  • In large quantities, these may cause health concerns, including increasing the risk of bowel cancer.

What are some ham alternatives?


Lean, minimally processed ham, prepared without excessive sodium or additives, can potentially be a part of a healthy overall diet. And parents in WA can continue packing ham in their child’s lunchbox. When choosing ham, read the labels and select products with a lower sodium content, minimal additives and healthier preparation methods.
When looking for low-salt alternatives to ham, there are several options to consider:
turkey breast. Turkey is a lean meat and can be a good substitute for ham. Look for low-sodium or no-salt-added varieties
chicken breast. Skinless, boneless chicken breast is a versatile and low-sodium option. Grilling, baking or roasting can add flavour without relying on salt
smoked salmon. While salmon naturally contains some sodium, smoked salmon tends to be lower in sodium than cured ham. Choose varieties with little or no added salt
roast beef. Choose lean cuts of roast beef and consider seasoning with herbs and spices instead of relying on salt for flavour
homemade roasts. Prepare your own roasts using lean meats such as pork loin, beef sirloin or lamb. This way, you have more control over the ingredients and can minimise added salt
grilled vegetables. These can be a tasty alternative to meat. Eggplant, zucchini, capsicum and portobello mushrooms have a satisfying texture and flavour
beans and legumes. Beans, lentils and chickpeas can be used as alternatives in various dishes. They are naturally low in sodium and high in protein and fibre.

What are some other lunchbox tips?

  • Consider planning ahead, involving your kids, reducing pre-packaged foods, balancing cost and convenience, and giving your kids lunchbox accountability.
  • Here's how to make it easier

    Remember to keep portions appropriate for kids and to consider any allergies or school regulations when packing lunches.


Lauren Ball works for The University of Queensland and receives funding from the National Health and Medical Research Council, Queensland Health and Mater Misericordia. She is a Director of Dietitians Australia, a Director of the Darling Downs and West Moreton Primary Health Network and an Associate Member of the Australian Academy of Health and Medical Sciences.

February is Heart Health Month: Blue Shield of California Offers Resources to Prioritize Heart Health All Year Long

Retrieved on: 
Thursday, February 8, 2024

OAKLAND, Calif., Feb. 8, 2024 /PRNewswire/ -- Each February marks Heart Health Month, which serves as an opportunity to raise awareness about heart disease and the importance of cardiovascular health. Heart disease is currently the leading cause of death in California and across the nation, and Blue Shield of California is joining the effort to encourage the adoption of heart-healthy practices throughout the year.

Key Points: 
  • Heart disease is currently the leading cause of death in California and across the nation , and Blue Shield of California is joining the effort to encourage the adoption of heart-healthy practices throughout the year.
  • Smoking damages blood vessels and increases the risk of heart disease, so seek support and resources to quit smoking.
  • Blue Shield offers Headspace to help with these practices, through its Wellvolution platform .
  • Heart health resources and programs for Blue Shield members:

Clear Cut Hero And X3 Performance & Physical Therapy Announce Partnership

Retrieved on: 
Thursday, February 8, 2024

LOUISVILLE, Ky., Feb. 8, 2024 /PRNewswire/ -- Clear Cut Hero, the first-of-its-kind hydration drink, announced a partnership with X3 Performance & Physical Therapy as the exclusive hydration provider for their 2024 NFL Combine and pre-NFL Draft training programs in Fort Myers, Florida and Nashville, Tennessee.

Key Points: 
  • LOUISVILLE, Ky., Feb. 8, 2024 /PRNewswire/ -- Clear Cut Hero , the first-of-its-kind hydration drink, announced a partnership with X3 Performance & Physical Therapy as the exclusive hydration provider for their 2024 NFL Combine and pre-NFL Draft training programs in Fort Myers, Florida and Nashville, Tennessee.
  • Clear Cut Hero will keep these elite players hydrated on their way to the biggest stage in professional sports.
  • Clear Cut Hero is the perfect source of hydration for X3 athletes enduring the rigors of training for the NFL Combine.
  • Joey Nickell, CEO of Clear Cut Brands–the parent company of Clear Cut Hero –also shared his enthusiasm for the new venture, stating, "The X3 team is a perfect fit to tell the Hero story.

Self-extinguishing batteries could reduce the risk of deadly and costly battery fires

Retrieved on: 
Tuesday, February 6, 2024

By modifying affordable commercial coolants to function as battery electrolytes, we were able to produce a battery that puts out its own fire.

Key Points: 
  • By modifying affordable commercial coolants to function as battery electrolytes, we were able to produce a battery that puts out its own fire.
  • We subjected these batteries to the nail penetration test, a common method for assessing lithium-ion battery safety.
  • Driving a stainless steel nail through a charged battery simulates an internal short circuit; if the battery catches fire, it fails the test.

Why it matters

  • High outdoor temperatures or uneven temperatures within a battery pack seriously threaten batteries’ safety and durability.
  • Energy-dense batteries, such as the lithium-ion versions that are widely used in electronics and electric vehicles, contain an electrolyte formulation dominated by organic molecules that are highly flammable.
  • As scientists studying energy generation, storage and conversion, we have a strong interest in developing energy-dense and safe batteries.

How we did our work

  • However, most known nonflammable organic solvents contain fluorine and phosphorus, which are expensive and can have harmful effects on the environment.
  • We focused on a mature, safe and affordable commercial fluid called Novec 7300, which has low toxicity, is nonflammable and does not contribute to global warming.

What still isn’t known

  • For this reason, our study focused predominantly on self-extinguishing potassium-ion batteries, although it also showed that our electrolyte works well for making self-extinguishing lithium-ion batteries.
  • If the industry embraces it, we expect that companies will be able to manufacture nonflammable batteries using their existing lithium-ion battery facilities.


Apparao Rao receives funding from the R. A. Bowen Endowed Professorship funds at Clemson University. Bingan Lu does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.