Juntendo University research: Potential immunotherapy approach to cervical cancer
TOKYO, Oct. 27, 2020 /PRNewswire/ --Researchers at Juntendo University report in the journal Molecular Therapy that specially prepared 'T cells' can be used to suppress cervical cancer.
- TOKYO, Oct. 27, 2020 /PRNewswire/ --Researchers at Juntendo University report in the journal Molecular Therapy that specially prepared 'T cells' can be used to suppress cervical cancer.
- Human papilloma virus (HPV) is known to cause different kinds of cancer, including cervical cancer.
- For cervical cancer, the scientists identified two proteins, known as E6 and E7, as targets for adoptive T cell therapy these oncoproteins are only expressed by cervical cancer cells, and not found in healthy tissue.
- Ando and colleagues have now explored a possible immunotherapy for cervical cancer, by developing specially prepared cells, toxic to cancer cells, derived from iPSCs.