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• SAN DIEGO, April 01, 2024 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: LIFE), a clinical stage biotechnology company engaged in the discovery and development of first-in-class medicines from its proprietary tRNA synthetase platform, today announced that the company will participate in two upcoming investor conferences scheduled to take place in April 2024.
• Details of the conferences appear below:
  For more information on how to register, please contact your Evercore ISI or Piper Sandler representative.
• aTyr is a clinical stage biotechnology company leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation.
• tRNA synthetases are ancient, essential proteins that have evolved novel domains that regulate diverse pathways extracellularly in humans.

• The U.S. FDA's approval of LIKMEZ highlighted Appili’s capacity to identify and develop significant opportunities within the infectious disease domain.
• Appili licensed the manufacturing and commercialization rights in the U.S. and other selected territories to Saptalis Pharmaceuticals, LLC (“Saptalis”).
• Appili, in collaboration with Saptalis, continued the product's development, ultimately achieving FDA approval in the United States.
• With FDA approval, future revenue is expected to be derived from milestone payments and royalties from Saptalis under the license agreement.

• MARIETTA, Ga., March 28, 2024 /PRNewswire/ -- BRIJ Medical proudly welcomes three distinguished industry leaders to its Board of Directors: John Grotting , Bob Zollars , and Jim Hinrichs .
• John Grotting, who joins BRIJ as Chairman of the Board, brings a wealth of executive leadership experience in healthcare and technology to BRIJ Medical.
• "We are thrilled to welcome John, Bob, and Jim to our Board of Directors," said Tim Gleeson , CEO of BRIJ Medical.
• The appointment of Grotting, Zollars, and Hinrichs to BRIJ Medical's Board of Directors marks a major milestone in the company's strategic journey.

• On Feb. 14, the U.S. National Oceanic and Atmospheric Administration announced that the whale was #5120 in a catalog that tracks individual right whales.
• Further, the agency said, rope that had been deeply embedded in the whale’s tail had likely come from lobster fishing gear in Maine.
• Entanglement in fishing gear is a deadly threat to these critically endangered animals.
• Scientists estimate that before commercial whaling scaled up in the 18th and 19th centuries, there may have been as many as 10,000 North Atlantic right whales.
• When whales become entangled in fishing gear, they use extra energy dragging it as they swim.

Smaller females are having fewer young

• By 2018 there were only about 73 breeding females left, representing roughly half of all females and a sixth of the entire species.
• Other research has shown that poor health and physical condition are making it harder for these females to even start breeding.
• Smaller whales have fewer calves.

• Many organizations are involved in tracking North Atlantic right whales, including government agencies, aquariums and conservation groups.
• Even females who have previously reproduced are less likely to breed again following an entanglement event.
• By identifying and photographing whales repeatedly over time, scientists can estimate different stages of their life, such as when females give birth.

Weakness of current regulations

• If they are larger and enter the blubber, they are classified as moderate.
• Our research makes it clear that such value-laden terms are potentially misleading because even minor entanglements can threaten whales’ successful reproduction.
• In our view, these measures do not give enough weight to preventing all types of entanglements, regardless of severity.
• And the plan closes trap fishing areas seasonally when whales are known to be present in those zones.

Coming back from the brink

• While these estimates seem promising, females need to start and continue producing calves to increase whales’ numbers.
• From our work, it is very clear that both lethal and sublethal impacts of entanglements are of grave concern for these whales.

• She also is a member of the International Whaling Commission Scientific Committee.
• Peter Corkeron consults for Public Employees for Environmental Responsibility on right whale conservation issues.
• Rob Harcourt receives funding from the Australian Federal Government Department of Climate Change, Environment, Energy and Water for research on right whales.