Cardiovascular disease

“The Weekly Check-Up Podcast” brings acclaimed healthcare talk radio show to larger audience

Retrieved on: 
Thursday, February 15, 2024

“Having produced more than a decade of ‘The Weekly Check-Up’ radio content, it's exciting to introduce a new platform to share the latest healthcare information with as many listeners as possible,” says host Dr. Bruce Feinberg.

Key Points: 
  • “Having produced more than a decade of ‘The Weekly Check-Up’ radio content, it's exciting to introduce a new platform to share the latest healthcare information with as many listeners as possible,” says host Dr. Bruce Feinberg.
  • Since the show began in 2011, Dr. Feinberg has amassed more than 500 hours of content featuring countless thought-provoking questions from listeners.
  • Dr. Feinberg will pair some of the most compelling content from the show’s archives with new, invaluable and practical answers and perspectives.
  • New episodes of “The Weekly Check-Up Podcast” will appear every other week on all major podcast platforms including Spotify, Apple Podcasts, and Google Podcasts.

New clinical trial shows that algae-based omega-3 lecithin AlmegaPL® provides better cardiovascular health support compared to traditional omega-3 fish oils

Retrieved on: 
Thursday, February 15, 2024

HOUSTON, Feb. 15, 2024 /PRNewswire/ -- Qualitas Health, LLC (dba iwi life) The results of a new clinical trial show evidence that the microalgae-derived AlmegaPL®, the foundational ingredient produced by iwi life™, delivers clinically relevant results decreasing triglycerides by 14% and remnant cholesterol such as very-low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL) by up to 25%.1,2  "This marks the second clinical trial endorsing the use of AlmegaPL® algal lecithin to support cardiovascular health in a generally healthy population," says Dr. Eneko Ganuza, a principal investigator who led the research.

Key Points: 
  • The new clinical trial led by Dr. Ganuza and sponsored by Qualitas Health was initiated to uncover just how effective an over-the-counter supplement can be in supporting cardiovascular health in the real-world population.
  • The findings support existing beliefs that EPA-only omega-3s like AlmegaPL® could provide greater cardiovascular benefits when compared to traditional sources of omega-3s like fish and krill oil that contain both EPA and DHA.
  • This highlights the use of naturally sourced AlmegaPL® algal oil as an over-the-counter supplement to help support cardiovascular health in the general healthy population."
  • There is something about the unique polar form in which this algal lecithin yields the omega-3s that prove highly beneficial to our heart health."

Life Line Screening, Nationwide Cardiovascular Health & Stroke Risk Screening Company, Announces Amanda Rangel as Senior Vice President of Global Business Solutions

Retrieved on: 
Thursday, February 15, 2024

Life Line Screening, the nation’s leading provider of mobile preventive health screenings for cardiovascular disease and stroke risk is pleased to announce the appointment of Amanda Rangel as Senior Vice President of Global Business Solutions.

Key Points: 
  • Life Line Screening, the nation’s leading provider of mobile preventive health screenings for cardiovascular disease and stroke risk is pleased to announce the appointment of Amanda Rangel as Senior Vice President of Global Business Solutions.
  • With her rich background in fostering corporate relationships, Amanda's expertise will be instrumental as Life Line Screening broadens its commercial outreach.
  • View the full release here: https://www.businesswire.com/news/home/20240215314328/en/
    Amanda Rangel, Senior VP of Global Business Solutions, Life Line Screening (Photo: Business Wire)
    Amanda Rangel comments on her new role: "I'm thrilled to join Life Line Screening at this pivotal moment of growth.
  • "Adding Amanda to our senior leadership team during a period of remarkable growth fortifies our direction," said Matt Miller, CEO of Life Line Screening.

Embrace Heart Health and the Power of Walnuts During American Heart Month

Retrieved on: 
Thursday, February 15, 2024

FOLSOM, Calif., Feb. 15, 2024 /PRNewswire/ -- A new survey1 from California Walnuts just revealed that only one-fifth of Americans (19%) say they eat enough walnuts to support a diet for heart health. With their exceptional nutritional profile, Americans are missing out on a delicious and easy way to support a healthy heart.

Key Points: 
  • Heart disease remains the leading cause of death in the U.S.,2 but research has shown that simple dietary changes can have a significant impact on heart health.
  • In recognition of American Heart Month, California Walnuts encourages Americans to embrace heart health by including walnuts in their daily diet.
  • Over the past three decades, studies have demonstrated the cardiovascular benefits of walnuts, exploring how eating walnuts affects various factors related to heart health such as cholesterol, blood pressure, inflammation and blood vessel function.
  • Visit walnuts.org/american-heart-month for heart-healthy recipe ideas, tips for maintaining freshness and more information about walnuts and heart health.

Cardio Diagnostics Holdings, Inc. Expands HeartRisk™ Platform Offering to Diverse Markets in Conjunction with Nationwide Rollout

Retrieved on: 
Thursday, February 15, 2024

Cardio Diagnostics Holdings, Inc. (Nasdaq: CDIO), an AI-driven precision cardiovascular medicine company, announced today the nationwide rollout and a significant expansion of its groundbreaking HeartRisk™ platform.

Key Points: 
  • Cardio Diagnostics Holdings, Inc. (Nasdaq: CDIO), an AI-driven precision cardiovascular medicine company, announced today the nationwide rollout and a significant expansion of its groundbreaking HeartRisk™ platform.
  • This expansion extends the reach of its proprietary data intelligence platform to correctional facilities, risk-bearing providers engaged in value-based contracts, and broker and benefits consultants.
  • "By expanding our HeartRisk™ platform, we're not just innovating within traditional healthcare sectors but breaking new ground in diverse markets.
  • From correctional facilities to value-based care providers and workplace wellness programs to brokerage and benefits consultants, our precision cardiovascular solutions provide actionable insights.

GoodRx Now Offering 30 Common Heart Health Medications for Under $30

Retrieved on: 
Thursday, February 15, 2024

GoodRx , the leading destination for prescription savings in the U.S., today announced it is offering 30 of the most common heart health medications for under $30 at more than 70,000 pharmacies nationwide.1 Cardiovascular disease is one of the most prominent conditions facing Americans, affecting nearly half of all U.S. adults.

Key Points: 
  • GoodRx , the leading destination for prescription savings in the U.S., today announced it is offering 30 of the most common heart health medications for under $30 at more than 70,000 pharmacies nationwide.1 Cardiovascular disease is one of the most prominent conditions facing Americans, affecting nearly half of all U.S. adults.
  • By helping people afford their prescriptions, GoodRx is improving health outcomes and reducing the overall strain on the healthcare system.
  • GoodRx’s recent report - The GoodRx Effect - estimates that GoodRx has directly contributed to the prevention of at least 140,000 emergency room visits and 110,000 hospitalizations for major adverse cardiovascular events like heart attack and stroke.
  • The following is a sample list of common generic medications used to treat cardiovascular disease that are available for under $30 on GoodRx.

Multi Board-Certified Physician Sam Setareh Opens MDVIP-Affiliated Primary Care Practice in Los Angeles

Retrieved on: 
Wednesday, February 14, 2024

LOS ANGELES and BOCA RATON, Fla., Feb. 14, 2024 /PRNewswire/ -- MDVIP, the market leader in personalized healthcare with a network of over 1,100 physicians nationwide, today announced the opening of a new MDVIP-affiliated internal medicine practice in Los Angeles. Sam Setareh, M.D., M.S., F.A.C.C., is currently accepting patients who want a more direct relationship with their primary care physician. Dr. Setareh brings an impressive and diversified background to MDVIP, including four board certifications in Internal Medicine, Cardiovascular Disease, Nuclear Cardiology and Echocardiology, and he is an attending physician at Cedars-Sinai Medical Center in Los Angeles.  Dr. Setareh serves as a member of multiple committees on the American College of Cardiology and the American Heart Association and as a founding member of the editorial board of The Journal of Scientific Innovation in Medicine.

Key Points: 
  • , is currently accepting patients who want a more direct relationship with their primary care physician.
  • Dr. Setareh brings an impressive and diversified background to MDVIP, including four board certifications in Internal Medicine, Cardiovascular Disease, Nuclear Cardiology and Echocardiology, and he is an attending physician at Cedars-Sinai Medical Center in Los Angeles.
  • "As an MDVIP-affiliated primary care physician, my mission is to help empower patients to take better control of their health through preventive medicine and highly individualized care," said Dr. Setareh, who has subspecialties in preventive cardiology, sports cardiology and advanced cardiovascular imaging.
  • He has treated and taken care of patients from all walks of life, including the most vulnerable to heads-of-state, dignitaries, athletes, celebrities and physician colleagues.

CPKC commits $1.5 million to support American Heart Association

Retrieved on: 
Wednesday, February 14, 2024

CALGARY, AB, Feb. 14, 2024 /PRNewswire/ - Canadian Pacific Kansas City (CPKC) and the American Heart Association (AHA) today announced they are teaming up again to save lives and improve heart health for people across the United States (U.S.) with our commitment of US$1.5 million for heart research over the next three years.

Key Points: 
  • CALGARY, AB, Feb. 14, 2024 /PRNewswire/ - Canadian Pacific Kansas City (CPKC) and the American Heart Association (AHA) today announced they are teaming up again to save lives and improve heart health for people across the United States (U.S.) with our commitment of US$1.5 million for heart research over the next three years.
  • The collaboration, started in 2015 in a single location, has grown into a national relationship spanning six states across the CPKC rail network, and is part of the CPKC Has Heart community investment program.
  • "We are incredibly grateful for CPKC's remarkable commitment to the American Heart Association.
  • Their critical support will allow our organization to advance lifesaving research and drive more equitable health for everyone, everywhere," said Kevin Harker, American Heart Association Executive Vice President, Midwest.

Reflection paper on investigation of pharmacokinetics in the obese population - Scientific guideline

Retrieved on: 
Wednesday, February 14, 2024

Reflection paper on investigations of pharmacokinetics in

Key Points: 
    • Reflection paper on investigations of pharmacokinetics in
      the obese population
      Table of contents
      1.
    • References .............................................................................................. 9

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 2/12

      1.

    • This is considered
      a shortcoming that is potentially compounded by obese patients often being poorly represented in
      clinical studies.
    • The specific aims of this reflection paper are to:
      ?

      describe how the effects of obesity can be investigated during clinical medicinal product
      development.

    • ?

      provide recommendations on when investigations of the effect of obesity on the PK of a
      medicinal product should be particularly considered.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 3/12

      ?

      discuss how to reflect PK (and/or PK/PD) findings in weight/weight-based dosing
      recommendations.

    • Absorption
      Reduced rate of absorption linked to locally reduced blood flow (8) is reported for the subcutaneous
      and transdermal routes in obese subjects.
    • Distribution
      The distribution of medicinal products is driven by body composition, regional blood flow and binding to
      tissue and plasma proteins.
    • Obese subjects have a larger absolute lean body weight (LBW) as well as fat mass.
    • The physicochemical properties of a medicinal product (lipophilicity, polarity, molecular size, and
      degree of ionization) influence its distribution in the body.
    • In BMI class III obese
      subjects, the blood flow per gram of fat is significantly lower than that observed in class I obese or
      lean subjects (4).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 4/12

      An increased amount of alpha-1-acid-glycoprotein (AAG), linked to a chronic inflammatory state, is
      reported in obese individuals.

    • Fatty infiltrations are present in the liver for 90% of obese subjects, with the extent of the infiltrations
      being proportional to the degree of obesity.
    • In some cases, in particular for CYP3A4 metabolized medicinal products,
      bodyweight normalized clearance can be lower in obese patients (23).
    • Based on presently available data, it has been suggested that uptake transporters

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 5/12

      are downregulated while efflux transporters may be upregulated (31).

    • Platelet hyper-reactivity is also observed,
      which can impair the response to anti-platelet medicinal products in obese patients (42, 43).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 6/12

      3.

      the medicinal product properties and scientific literature indicate that obesity may lead to a
      marked effect on elimination and/or distribution or on the PK/PD relationship.

    • These
      models may aid in extrapolating the known efficacy and safety in the non-obese population to the
      obese population.
    • The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients
      Before and One Year After Bariatric Surgery.
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 11/12

      41.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 12/12

Henry Schein Cares Foundation Launches ‘Prevention is Power’ Public Health Awareness Campaign

Retrieved on: 
Wednesday, February 14, 2024

Henry Schein, Inc. (Nasdaq: HSIC) today announced the launch of Prevention is Power™, a multi-year public health awareness campaign from the Henry Schein Cares Foundation, Inc. (HSCF) to help improve health literacy and strengthen patient utilization of integrated, preventive care, with the goal of reducing incidences of chronic diseases as well as overall health care spending.

Key Points: 
  • Henry Schein, Inc. (Nasdaq: HSIC) today announced the launch of Prevention is Power™, a multi-year public health awareness campaign from the Henry Schein Cares Foundation, Inc. (HSCF) to help improve health literacy and strengthen patient utilization of integrated, preventive care, with the goal of reducing incidences of chronic diseases as well as overall health care spending.
  • Chan School of Public Health, the Commonwealth Fund, and others, despite spending more on health care than any other high-income country, overall health outcomes in the U.S. trail those in its peer countries.
  • It is well established that patient utilization of routine preventive health care leads to better population health outcomes as well as lower overall health care costs.
  • The Gold Foundation, which champions the human connection in health care, is proud to partner with the Henry Schein Cares Foundation to expand access and address health inequities.”
    Dr. Ayman El-Mohandes, Dean of CUNY SPH: “We are thrilled to partner with two impactful organizations, the Henry Schein Cares Foundation and NACHC, in this important work aimed at improving patient outcomes through education and engagement.