Feinstein Institute for Medical Research

Feinstein Institutes Bioelectronic Medicine Researchers Target Specific Vagus Nerve Fibers for More Precise, Effective Stimulation

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Friday, November 4, 2022
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A new paper published in Brain Stimulation showed that delivering high-frequency electrical stimulation activates specific sensory nerve fibers of the vagus nerve and could be the key to better targeting and treating inflammation and disease.

Key Points: 
  • A new paper published in Brain Stimulation showed that delivering high-frequency electrical stimulation activates specific sensory nerve fibers of the vagus nerve and could be the key to better targeting and treating inflammation and disease.
  • View the full release here: https://www.businesswire.com/news/home/20221104005611/en/
    Dr. Stavros Zanos recently led the study, which targets specific fibers in the vagus nerve for more precise electrical stimulation.
  • (Credit: Feinstein Institutes)
    The research study, led by Stavros Zanos, MD, PhD , associate professor at the Feinstein Institutes Institute of Bioelectronic Medicine , measured how vagus nerve stimulation (VNS) using kHz stimulation an electrical stimulus that is commonly used to block nerve conduction at over 1,000 pulses per second affects the activity of different types of vagal fibers.
  • Previous VNS therapies would stimulate the whole nerve bluntly, without targeting specific fibers, which could cause adverse effects and less effective therapy.

Medical Device Venture Lazzaro Medical Secures $1M from Northwell Heath

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Thursday, October 27, 2022
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BOULDER, Colo., Oct. 27, 2022 /PRNewswire-PRWeb/ -- Lazzaro Medical, a Boulder-based medical device company seeking to help millions of people suffering from Tracheobronchomalacia (TBM), received a $1 million strategic investment from Northwell Health, New York State's largest healthcare provider.

Key Points: 
  • BOULDER, Colo., Oct. 27, 2022 /PRNewswire-PRWeb/ -- Lazzaro Medical , a Boulder-based medical device company seeking to help millions of people suffering from Tracheobronchomalacia (TBM), received a $1 million strategic investment from Northwell Health, New York State's largest healthcare provider.
  • Previous treatment was worse than the disease for many potential patients," said Dr. Lazzaro, Co-Founder and Chief Medical Officer of Lazzaro Medical.
  • "We're thrilled to welcome this strategic investment from Northwell, a world-class leader driving innovation in patient outcomes and care," saidRob Israel, Co-Founder and CDO of Lazzaro Medical.
  • For more information on Lazzaro Medical, please visit Lazzaromed.com , or follow @Lazzaro Medical on LinkedIn .

Feinstein Institutes Awarded $6.7M From NIH to Create First Human Vagus Nerve Anatomical Map

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Wednesday, October 26, 2022
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(Credit: Feinstein Institutes)

Key Points: 
  • (Credit: Feinstein Institutes)
    The landmark funding is part of the NIH Common Funds Stimulating Peripheral Activity to Relieve Conditions (SPARC) program .
  • How sensory and motor fibers are arranged inside the vagus nerve and pathways to different organs are essentially unknown.
  • The vagus nerve, which means wandering in Latin, runs from the brainstem to most of the bodys major organs.
  • Through the use of electrical stimulation of the vagus nerve (VNS), researchers at the Feinstein Institutes and elsewhere try to reset vagus nerve activity and fight inflammation.

Feinstein Institutes, Northwell electrophysiologist successfully implant first modular cardiac rhythm management system in novel clinical trial

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Friday, October 21, 2022
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Like a paramedic in your chest, a team of Northwell Health clinicians, electrophysiologists and clinical trial investigators at The Feinstein Institutes for Medical Research successfully implanted a modular cardiac rhythm management (CRM) system in the first patient to be enrolled in the Boston Scientific MODULAR ATP clinical trial.

Key Points: 
  • Like a paramedic in your chest, a team of Northwell Health clinicians, electrophysiologists and clinical trial investigators at The Feinstein Institutes for Medical Research successfully implanted a modular cardiac rhythm management (CRM) system in the first patient to be enrolled in the Boston Scientific MODULAR ATP clinical trial.
  • View the full release here: https://www.businesswire.com/news/home/20221021005348/en/
    Laurence M. Epstein, MD (center right) implanted the first patient in Boston Scientifics MODULAR ATP clinical trial at North Shore University Hospital.
  • The trial will also investigate the system and procedure-related complication-free rate of the EMPOWER MPS.
  • The MODULAR ATP trial will enroll up to 60 centers in the U.S., Canada and Europe up to 300 patients.

Feinstein Institutes urges areas of focus to improve preventative lung cancer screenings

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Friday, October 14, 2022
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Approximately 130,000 people will die from lung cancer in 2022, making it the most common cause of cancer death in the United States.

Key Points: 
  • Approximately 130,000 people will die from lung cancer in 2022, making it the most common cause of cancer death in the United States.
  • View the full release here: https://www.businesswire.com/news/home/20221014005372/en/
    Karina Davidson, PhD, is the director of the Institute of Health System Science at the Feinstein Institutes.
  • (Credit: Feinstein Institutes for Medical Research)
    To address the growing lung cancer crisis in 2014, the U.S. Preventative Services Task Force (USPSTF) expanded lung cancer screening guidelines for certain people.
  • Dr. Davidsons thoughtful review of current lung cancer screening guidelines and gaps that should be addressed is timely and important.

Feinstein Institutes’ fifth Bioelectronic Medicine Summit spotlights innovation, future of science

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Thursday, October 13, 2022
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Some of the most influential international medical experts, researchers and scientific minds participated in the fifth Bioelectronic Medicine Summit, Bioelectronic Medicine: Todays Tools, Tomorrows Therapies , hosted by The Feinstein Institutes for Medical Research .

Key Points: 
  • Some of the most influential international medical experts, researchers and scientific minds participated in the fifth Bioelectronic Medicine Summit, Bioelectronic Medicine: Todays Tools, Tomorrows Therapies , hosted by The Feinstein Institutes for Medical Research .
  • View the full release here: https://www.businesswire.com/news/home/20221013005978/en/
    Dr. Kevin J. Tracey delivers a keynote address at the Bioelectronic Medicine Summit.
  • Anil Malhotra , MD, co-director of the Institute of Behavioral Science at the Feinstein Institutes, explained how bioelectronic medicine could help treat neuropsychiatric disorders.
  • The Feinstein Institutes, the global scientific home of bioelectronic medicine, continues to invest in bioelectronic medicine.

Health Care in a World of Change: Northwell Health Hosts Fifth Annual Constellation Forum

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Tuesday, October 11, 2022
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To better understand our progress and current challenges preventing innovation, Northwell Health , New York States largest health system, will host its fifth annual Constellation Forum virtually on October 20 at 11 a.m.

Key Points: 
  • To better understand our progress and current challenges preventing innovation, Northwell Health , New York States largest health system, will host its fifth annual Constellation Forum virtually on October 20 at 11 a.m.
  • View the full release here: https://www.businesswire.com/news/home/20221011006114/en/
    Michael Dowling, president and CEO of Northwell Health speaks at a past Constellation Forum.
  • (Credit: Northwell Health)
    Northwell Health President and CEO Michael Dowling will host the forum, featuring insights from industry titans, scientific leaders and innovators.
  • Northwell Health is New York States largest health care provider and private employer, with 21 hospitals, 850 outpatient facilities and more than 12,000 affiliated physicians.

Feinstein Institutes Scientists Outline in Neuron Bioelectronic Medicine Advances, Future of Clinical Care

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Monday, October 10, 2022
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View the full release here: https://www.businesswire.com/news/home/20221010005549/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20221010005549/en/
    Valentin Pavlov, PhD, professor in the Institute of Bioelectronic Medicine at the Feinstein Institutes, is one of the co-authors of the new article recently published in Neuron.
  • (Credit: Feinstein Institutes)
    The Feinstein Institutes is the global scientific home of bioelectronic medicine.
  • Investigators within the Institute of Bioelectronic Medicine at the Feinstein Institutes have studied the use of electricity to target nerves to control inflammation within the body for more than two decades.
  • Encompassing 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health system science, and molecular medicine.

High-frequency Electrical Stimulation Helps Reduce Inflammation, Pain in New Feinstein Institutes Study

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Wednesday, October 5, 2022
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And while pain is an important defense mechanism to protect the body and promote healing, chronic pain can be debilitating.

Key Points: 
  • And while pain is an important defense mechanism to protect the body and promote healing, chronic pain can be debilitating.
  • The research, led by Feinstein Institutes Sangeeta Chavan, PhD , showed in preclinical mice models that HFES inhibits neuroinflammatory mediator release by sensory neurons, called nociceptors, to reduce pain.
  • For your body to feel pain, neurons release molecules that kickstart the bodys immune response causing inflammation and pain.
  • We now have a better understanding as to why high-frequency stimulation helps attenuate inflammation and associated pain.

LUSTGARTEN FOUNDATION FLAGSHIP WALK INSPIRES COMMUNITY AND RAISES CRITICAL DOLLARS FOR PANCREATIC CANCER RESEARCH

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Monday, October 3, 2022
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WOODBURY, N.Y., Oct. 3, 2022 /PRNewswire/ -- Long Island residents touched by pancreatic cancer gathered for a day of remembrance, action, and hope at Sunday's walk for pancreatic cancer research at Jones Beach State Park. The annual walk has raised more than $19 million since 2001, and 100% of all donations fund life-saving research.  

Key Points: 
  • The 5-year survival rate for pancreatic cancer patients has more than doubled since the Lustgarten Foundation began in 1998.
  • The Lustgarten Foundation funds the world's preeminent pancreatic cancer researchers, driving the pursuit of bold and innovative science toward earlier detection, better treatments and transforming pancreatic cancer into a curable disease.
  • The Foundation is a catalystLustgarten-funded science has been a driving force in every major advancement in pancreatic cancer research since 1998.
  • The Lustgarten Foundation is the world's largest private funder of pancreatic cancer research and 100% of all donations fuel the research to advance understanding of this complex, devastating and historically underfunded cancer.