Suffering

Why you may feel depressed and anxious when you're ill – and how to cope with it

Retrieved on: 
Tuesday, January 16, 2024

All have one thing in common: they can make you feel miserable.

Key Points: 
  • All have one thing in common: they can make you feel miserable.
  • These illnesses often come with fatigue, lack of appetite and concentration difficulties.
  • To be successful, they need to rally other immune cells as well as several organs of your body.
  • But you can also be more sensitive to negative stimuli, which can easily make you sad and anxious.


That means that the psychological experience of sickness is not just triggered by your brain or the pathogen itself – it seems to be unleashed by your own immune system.

Making people sick for one day

  • Researchers have actually shown that such feelings can be brought about without a true pathogen being present.
  • My research group, and a few others in the world, purposely activate the natural immune defences of healthy and young volunteers, without using a pathogen.
  • And the sickness feelings, including the strong negative emotions that were triggered only a few hours earlier, also subsided within this time frame.

Why do we feel miserable during infections?

  • Well, even if you are not fully aware of it, fighting a pathogen requires an incredible amount of energy.
  • Both the activity of your immune cells and the increase in body temperature take a heavy toll.
  • Do not feel guilty or worried about feeling miserable – it’s only natural.
  • And by the way, if you feel miserable in the days following a vaccination… Don’t worry – it similarly means your immune system is at work.


Julie Lasselin receives funding from the Swedish Research Council (vetenskapsrådet), Riksbankens Jubileumsfond, and the Osher center for Integrative Health at Karolinska Institutet.

FDI World Dental Federation calls for global leaders to prioritise action against oral diseases at major UN meeting on health

Retrieved on: 
Monday, March 20, 2023

GENEVA, March 20, 2023 /PRNewswire/ -- 

Key Points: 
  • Call issued on World Oral Health Day, as data shows oral diseases impact nearly half the world's population
    Today, FDI World Dental Federation (FDI) called on governments and global health bodies to prioritise action against oral diseases, including through integrating oral health at the United Nations (UN) High Level Meeting (HLM) on Universal Health Coverage (UHC) discussions in September.
  • There are nearly one billion more cases of oral diseases than all five major noncommunicable diseases (cardiovascular diseases, diabetes, chronic respiratory diseases, cancers and mental disorders) combined.
  • "We welcome the growing momentum on oral health, including the upcoming adoption of the Global Oral Health Action Plan, which aligns with FDI's Vision 2030 to Delivering Optimal Oral Health For All .
  • World Oral Health Day is a great opportunity for oral health professionals, policymakers, academics and the broader global community to promote the importance of positive attitudes towards oral healthcare.

New study reveals the extent of antibiotic misuse for a common sore throat, fuelling the 3rd leading cause of death worldwide

Retrieved on: 
Friday, November 18, 2022

Upper respiratory tract infections represent the leading cause for global antibiotic misuse in adults.

Key Points: 
  • Upper respiratory tract infections represent the leading cause for global antibiotic misuse in adults.
  • The STAR study findings suggest that a misunderstanding of how to treat sore throats is contributing to antibiotic overuse.
  • GRIP is calling for awareness and education on appropriate antibiotic use and urging young people to ask questions to help fight antibiotic resistance."
  • For more information or interviews with GRIP experts Sabiha Essack & Martin Duerden: [email protected] , +44 20 8154 6389
    View original content to download multimedia: https://www.prnewswire.com/news-releases/new-study-reveals-the-extent-of...

New study reveals the extent of antibiotic misuse for a common sore throat, fuelling the 3rd leading cause of death worldwide

Retrieved on: 
Friday, November 18, 2022

Upper respiratory tract infections represent the leading cause for global antibiotic misuse in adults.

Key Points: 
  • Upper respiratory tract infections represent the leading cause for global antibiotic misuse in adults.
  • The STAR study findings suggest that a misunderstanding of how to treat sore throats is contributing to antibiotic overuse.
  • GRIP is calling for awareness and education on appropriate antibiotic use and urging young people to ask questions to help fight antibiotic resistance."
  • For more information or interviews with GRIP experts Sabiha Essack & Martin Duerden: [email protected] , +44 20 8154 6389

EffRx Pharmaceuticals Signs Exclusive License Agreement With Diurnal for the Registration and Commercialization of Efmody® in Switzerland

Retrieved on: 
Tuesday, April 26, 2022

EffRx Pharmaceuticals SA, a commercial-stage company that commercializes niche and orphan medicines in Switzerland and Europe, today announced it has recently entered into an exclusive license agreement with Diurnal Group plc, for the registration and commercialization of Efmody as treatment for congenital adrenal hyperplasia (CAH) in Switzerland.

Key Points: 
  • EffRx Pharmaceuticals SA, a commercial-stage company that commercializes niche and orphan medicines in Switzerland and Europe, today announced it has recently entered into an exclusive license agreement with Diurnal Group plc, for the registration and commercialization of Efmody as treatment for congenital adrenal hyperplasia (CAH) in Switzerland.
  • Under the terms of the agreement EffRx has received the exclusive rights to register and commercialize Efmody in Switzerland.
  • The MAA submission to Swissmedic for Efmody will be based on the European regulatory dossier and published clinical trial data, with EffRx expecting potential market launch in Switzerland in 2024.
  • We are pleased to deepen our relationship with EffRx to include the distribution and marketing of Efmody in Switzerland.

NEW UB40 ALBUM FEATURING ALI CAMPBELL & ASTRO UNPRECEDENTED TO BE RELEASED JUNE 17 VIA UMe

Retrieved on: 
Friday, April 15, 2022

LOS ANGELES, April 15, 2022 /PRNewswire/ -- UB40 Featuring Ali Campbell & Astro will release their new album Unprecedented, June 17 via UMe. The album will be released as a black 2LP, a limited-edition white-color 2LP, 1CD, limited-edition cassette as well as digitally. All formats include their new single "Sufferer", which Ali has dedicated to his beloved friend and bandmate of over four decades, Astro, who tragically passed away last November.

Key Points: 
  • LOS ANGELES, April 15, 2022 /PRNewswire/ --UB40 Featuring Ali Campbell & Astro will release their new album Unprecedented, June 17 via UMe.
  • The album will be released as a black 2LP, a limited-edition white-color 2LP, 1CD, limited-edition cassette as well as digitally.
  • '"Sufferer,' is a song that Astro and I have always loved, from the brilliant Kingstonians," comments Ali.
  • This song is more poignant and special than I ever realized after Astro heartbreakingly passed awayafter recording this album.

OWC Joins the Music Showcasing Innovative Connectivity and Storage Solutions at SXSW 2022

Retrieved on: 
Thursday, March 10, 2022

Presented by Give A Note Foundation and Artist For Artist on Friday, March 18 at SXSW 2022.

Key Points: 
  • Presented by Give A Note Foundation and Artist For Artist on Friday, March 18 at SXSW 2022.
  • OWC will also be supporting Jam in the Van at SXSW 2022 as its sponsor.
  • OWC will give daily prizes and showcase its latest products for film, media, and music creators on March 16-20.
  • OWC will present award-winning external hard drive solutions, expansion products, docking and connectivity solutions.

Metallica, P!nk, Twenty One Pilots and Luke Combs to Headline BottleRock Napa Valley

Retrieved on: 
Monday, January 10, 2022

BottleRock Napa Valley, presented by JaM Cellars, announces the 2022 festival lineup today, featuring over 75 musical acts including headline artists Metallica, P!nk, Twenty One Pilots and Luke Combs.

Key Points: 
  • BottleRock Napa Valley, presented by JaM Cellars, announces the 2022 festival lineup today, featuring over 75 musical acts including headline artists Metallica, P!nk, Twenty One Pilots and Luke Combs.
  • (Photo: Business Wire)
    The three-day music, wine, craft brew and culinary festival will take place in the heart of the City of Napa at the Napa Valley Expo on May 27-29, 2022.
  • BottleRock Napa Valley also presents its highly entertaining Williams Sonoma Culinary Stage, showcasing a unique mashup of cooking demonstrations with renowned chefs, celebrities, performers and rock stars.
  • Join the conversation on Facebook and follow us on Twitter (@BottleRockNapa, #BottleRock) Instagram (@BottleRockNapa, #BottleRock) and TikTok (@bottlerocknapa, #BottleRock).

Unity HA Adds Jon J. Snyder as CEO, Announces Name Change to Realeve™

Retrieved on: 
Wednesday, August 18, 2021

Unity HA today announced the addition of Jon J. Snyder as Chief Executive Officer.

Key Points: 
  • Unity HA today announced the addition of Jon J. Snyder as Chief Executive Officer.
  • The company also announced the change of their name from Unity HA, to Realeve, to support the commercialization process for their Pulsante SPG Microstimulator System for cluster headache.
  • Unity HA Founder, Dr. Peter Bonutti said, "We are extremely pleased to add a proven, medical device executive with strong neuromodulation and chronic pain therapy development experience in Jon Snyder to lead Realeve going forward."
  • Snyder added, "It is an honor to join the Realeve team and move this impactful therapy closer to the market.

Hybrid/Virtual/Decentralized Clinical Trials Market Outlook Report 2021: Hybrid Trial Use and Experience, Provider Selection, Provider Perceptions, Future Predictions, Study Data - ResearchAndMarkets.com

Retrieved on: 
Wednesday, August 4, 2021

The industry had no choice but to adapt to maintain any sort of momentum on clinical development activities.

Key Points: 
  • The industry had no choice but to adapt to maintain any sort of momentum on clinical development activities.
  • The publisher surveyed 109 respondents at sponsors and CROs regarding their experiences with hybrid trials and providers of these services.
  • Though not all reported a smooth, pain-free experience, nearly two-thirds of respondents came away with a positive overall impression of hybrid trials.
  • 83% of respondents expect that the hybrid trial model will be used more frequently than the traditional trial model three years from now.