CHOP Researchers Develop Versatile and Low-Cost Technology for Targeted Long-read RNA Sequencing
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Tuesday, August 15, 2023
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PHILADELPHIA, Aug. 15, 2023 /PRNewswire/ -- In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules. The technology, called TEQUILA-seq, is highly cost-effective compared to commercially available solutions for targeted RNA sequencing and can be adapted for different research and clinical purposes. The details were described in a paper in Nature Communications.
Key Points:
- The technology, called TEQUILA-seq, is highly cost-effective compared to commercially available solutions for targeted RNA sequencing and can be adapted for different research and clinical purposes.
- "Targeted long-read RNA sequencing is a powerful strategy for elucidating the RNA repertoire for any predefined set of genes.
- They are compatible for both targeted RNA and DNA sequencing, on both long-read and short-read sequencing platforms.
- "TEQUILA-seq: A versatile and low-cost method for targeted long-read RNA sequencing," Nature Communications, August 8, 2023, DOI: 10.1038/s41467-023-40083-6