ObsEva Announces Two Cornerstone Publications Describing Clinical Trials of Nolasiban for Improving Pregnancy and Live Birth Outcomes Following IVF
The first paper, entitled Effect of the oxytocin receptor antagonist nolasiban on pregnancy rates in women undergoing embryo transfer following IVF: analysis of three randomized clinical trials (Griesinger et al), was published in the Journal of Human Reproduction.
- The first paper, entitled Effect of the oxytocin receptor antagonist nolasiban on pregnancy rates in women undergoing embryo transfer following IVF: analysis of three randomized clinical trials (Griesinger et al), was published in the Journal of Human Reproduction.
- The study reports the results from a meta-analysis of three randomized, placebo-controlled trials showing that nolasiban increased the likelihood of live birth following IVF.
- The analyses also showed that the effect size for nolasiban was similar for ongoing pregnancy rate and live birth rate.
- Population pharmacokinetic analyses indicated that higher exposures of nolasiban were associated with a higher probability of pregnancy.