Feces

Noster Microbiome Research: Analyzing Bacterial Digest

Retrieved on: 
Friday, December 2, 2022
Bacteria, Human, Feces, LC-MS/MS, Fat, Health, Virus, Sugar, Animal, Tissue, Enzyme, Protein, Dihydroxy-E,Z,E-PUFA, LC, Keio University, Carbohydrate, Mouse, Dietary supplement, Perfume, Liquid

Carbohydrates, such as sugars, fibers and starches, for example, require bacterial intervention to be properly broken down.

Key Points: 
  • Carbohydrates, such as sugars, fibers and starches, for example, require bacterial intervention to be properly broken down.
  • The scientists tested their method by analyzing mouse feces; they successfully detected several fatty acid metabolites produced by the gut microbiota.
  • It combines liquid chromatography, a technique used for physically separating substances, and mass spectroscopy, used for analyzing masses of substances.
  • LC-MS/MS can be used for analyzing a wide range of chemical compounds, including metabolites.

Synlogic Announces SYNB1353 Achieves Proof of Mechanism for Treatment of Homocystinuria and Provides Business Update

Retrieved on: 
Wednesday, November 30, 2022
Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Probiotic, Risk, MAD, AbbVie, GI, Therapy, Roche, Synthetic biology, Homocystinuria, Inflammatory bowel disease, Phenylketonuria, Nature, Catastrophic optical damage, Șaeș, Blood, Patient, IBD, PKU, Genetic engineering, Gout, Fast Track, Workforce, Diet, Plasma, FDA, Methionine, Feces, Food, Uric acid, Urine, Ginkgo, Cystathionine, Disease, CBS, Orphan, Frequency, News, Research, AES, Clinical trial, Safety, Metabolism, AUC, Frank Lenti, Homocysteine, AE, Gastrointestinal tract, Absorption, ODD, Pharmaceutical industry, Risk management, Dietary supplement, Mineral wool, HCU

CAMBRIDGE, Mass., Nov. 30, 2022 (GLOBE NEWSWIRE) -- Synlogic, Inc. (Nasdaq: SYBX), a clinical-stage biotechnology company developing medicines for metabolic and immunological diseases through its proprietary approach to synthetic biology, today announced that SYNB1353 has achieved proof of mechanism and positive results in a Phase 1 study in healthy volunteers treated with multiple ascending doses of SYNB1353.  SYNB1353 is an orally administered, non-systemically absorbed drug candidate designed to consume methionine in the GI tract for the potential treatment of homocystinuria (HCU). 

Key Points: 
  • SYNB1353 is an orally administered, non-systemically absorbed drug candidate designed to consume methionine in the GI tract for the potential treatment of homocystinuria (HCU).
  • The Company also shared that the FDA has granted Orphan Drug Designation (ODD) to SYNB1353 for the treatment of HCU.
  • This dietary model was intended to capture in healthy volunteers a transient elevation in methionine following a meal challenge, in order to demonstrate proof of mechanism of consumption of methionine by SYNB1353.
  • Dosing of SYNB1353 resulted in a reduction in plasma methionine when measured over 24-hours as area under the curve (AUC) following a methionine meal challenge.

New Photonics Research to Solve for Environmental Challenges

Retrieved on: 
Thursday, November 17, 2022
Environment, Climate Change, Environmental Issues, Environmental Health, Sustainability, Philanthropy, Alternative Energy, Green Technology, Energy, Foundation, ICFO, Student, CO2, Feces, Environment, Hand, Engineering, Publication, Picardi, Temperature, Science, First Nations in Ontario, Research, Climate change, Light, Intergovernmental Panel on Climate Change, Biophysical environment, Methane, University, Air pollution, Electricity, United Nations, Map, Risk, Health, Drinking water, University of Eldoret, Water, OSA, Diarrhea, Knowledge, Renewable energy, Medical imaging, 3D printing, Optica, Dhakal

Today, the Optica Foundation released details of promising photonics research solving for global environmental challenges.

Key Points: 
  • Today, the Optica Foundation released details of promising photonics research solving for global environmental challenges.
  • This photonics research seeks novel and powerful approaches to address critical environmental issues, said Alan Willner, chair of the 20th Anniversary Challenge Selection Committee and 2016 Optica President.
  • Now, with applied research from Ashim Dhakal, Phutung Research Institute, Nepal, a cost-effective and efficient option may be on the near horizon.
  • Michela Florinda Picardi, ICFO The Institute of Photonics Sciences, Spain
    Every process, industrial or natural, generates heat as a byproduct.

InventHelp Inventor Develops a Device to Keep Sewer Lines Clean (TNO-158)

Retrieved on: 
Tuesday, November 8, 2022
Maintenance, Paper, Multimedia, Ninth Street, Sale, Feces, Sewage

The invention is used to grind toilet paper, feces, grease, and other waste matter to help prevent clogs in the sewer lines and system.

Key Points: 
  • The invention is used to grind toilet paper, feces, grease, and other waste matter to help prevent clogs in the sewer lines and system.
  • It prevents any return backup, reducing any potential related sewage odors, mold, or bacteria buildup in relation to clogs and backups associated with toilets, sinks, shower drains, etc.
  • The original design was submitted to the New Orleans sales office of InventHelp.
  • 21-TNO-158, InventHelp, 217 Ninth Street, Pittsburgh, PA 15222, or call (412) 288-1300 ext.

Global External Urine Management Products Market Report 2022: Rising Rates of Incontinence Driving Sector Growth - ResearchAndMarkets.com

Retrieved on: 
Thursday, November 3, 2022
Medical Devices, Medical Supplies, Hospitals, Cardiology, Other Health, Biotechnology, Managed Care, Health, Science, Other Science, Online, Patient, Awareness, Gynaecology, Growth, Society, World, Urinary incontinence, Obesity, Blood, Risk, CAGR, World Health Organization, Degenerative disease, Government, Projection, Ageing, Population, Incidence, WHO, Nursing, Feces, Hypertension, Urine, UI, Cardiac catheterization, Urology, Organization, Anatomy, American Society of Nephrology, Kidney, Thrombosis, Medicine, Urinary bladder, Moyamoya disease, Prevalence, Incontinence, Diabetes, Distribution, Technology, CAPS, Catheter, Hospital, Program, Solution, Medical device, Health insurance

The Global External Urine Management Products Market size is expected to reach $752.5 Million by 2028, rising at a market growth of 5.0% CAGR during the forecast period.

Key Points: 
  • The Global External Urine Management Products Market size is expected to reach $752.5 Million by 2028, rising at a market growth of 5.0% CAGR during the forecast period.
  • Transitioning from sanctifying grace catheters to autonomous continence is made possible by the cutting-edge external urine management device for anatomy.
  • Fit, securement, and performance are the issues that must be addressed for urine incontinence to be properly managed.
  • The rising demand for urinary catheters around the world is mostly due to the high prevalence of urine incontinence.

InventHelp Inventor Develops a Device to Keep Sewer Lines Clean (TNO-158)

Retrieved on: 
Thursday, October 27, 2022
Sale, Maintenance, Multimedia, Paper, Feces, Ninth Street, Sewage

The invention is used to grind toilet paper, feces, grease, and other waste matter to help prevent clogs in the sewer lines and system.

Key Points: 
  • The invention is used to grind toilet paper, feces, grease, and other waste matter to help prevent clogs in the sewer lines and system.
  • It prevents any return backup, reducing any potential related sewage odors, mold, or bacteria buildup in relation to clogs and backups associated with toilets, sinks, shower drains, etc.
  • The original design was submitted to the New Orleans sales office of InventHelp.
  • 21-TNO-158, InventHelp, 217 Ninth Street, Pittsburgh, PA 15222, or call (412) 288-1300 ext.

Ehrlich Pest Control's Top Five Creepy Pests this Halloween Season

Retrieved on: 
Monday, October 24, 2022
LinkedIn, Mecoptera, Nausea, Fluid mechanics, Science, Feces, Reptile, Bird, District, Pulse, Degenerative disease, TAP, Bee, House, Blood, Swelling, Pain, Chagas disease, Environment, Maintenance, Scorpion, Pest control, Caterpillar, Solution, Human, Trapping, Agriculture, Cochineal, Rentokil Initial, Facebook

READING, Pa., Oct. 24, 2022 /PRNewswire/ -- With Halloween rapidly approaching, people are gearing up to present their scariest costumes and scenes. Few things can cause a person's heart to skip a beat like a slithering, crawling pest. As part of this year's spooky season, Ehrlich Pest Control compiled a list of its top five nightmare-inducing pests.

Key Points: 
  • As part of this year's spooky season, Ehrlich Pest Control compiled a list of its top five nightmare-inducing pests.
  • Thomas Dobrinska, a board-certified entomologist for Ehrlich Pest Control, provided his five creepiest pests for this Halloween season.
  • Top five pests to watch out for this Halloween season:
    Triatomine "kissing" bug:This nocturnal pest feeds on the blood of almost anything with a pulse.
  • Rentokil and its companies, including Florida Pest Control, Western Exterminator and Presto-X Pest Control, provide commercial and residential pest control to customers in the United States and Canada.

ASPCA Assists Suffolk County District Attorney's Office with Rescue of Nearly 300 Neglected Animals from Hoarding Situation on Long Island

Retrieved on: 
Wednesday, October 19, 2022
ASPCA, Denver District Attorney's Office, American Society for the Prevention of Cruelty to Animals, District attorney, Bird, Feces, Society, Urine, Twitter, Instagram, Dog, Multimedia, Partnership, Human, Hoarding, CEO, Snake, Safety, Rabbit, Town, Cockroach, Health, Local government, View, Cat, Animal, Private investigator, Online gambling, Facebook, Animal

BROOKHAVEN, N.Y., Oct. 18, 2022 /PRNewswire/ -- At the request of the Suffolk County District Attorney's Office, the ASPCA® (American Society for the Prevention of Cruelty to Animals®) urgently mobilized more than 20 responders to assist with the rescue of nearly 300 neglected animals from a home in Brookhaven, N.Y. The animals, including cats, rabbits, birds, tortoises, and snakes, are being removed from a hoarding situation where they were living in overcrowded conditions among filth – many surrounded by their own feces and urine and covered in vermin including cockroaches. Some of the animals were also suffering from untreated medical conditions.

Key Points: 
  • The ASPCA is assisting with operational planning and removal, evidence collection and crime scene documentation, legal and investigative assistance, and forensic exams.
  • The ASPCA is also helping to transport the animals to local shelters and rescue groups throughout New York where they will receive much-needed care.
  • Criminal charges resulting from this case are being prosecuted by the Suffolk County District Attorney's Office.
  • Last year, the ASPCA assisted the Suffolk County District Attorney's Office with the rescue of more than 80 dogs from an animal fighting operation.

Experimental Treatment Approach Counters Allergic Asthma without Weakening Flu Defenses

Retrieved on: 
Friday, October 7, 2022
Tao, National Institutes of Health, Medical research, NYU, New York University Grossman School of Medicine, Novo Nordisk Foundation, Science Advances, National, Icahn School of Medicine at Mount Sinai, Lung, German Research Foundation, Pathology, Virus, Feces, Infection, Inflammation, Breathe Me, Mouse, Center, Department, Mount Sinai School, Korea Disease Control and Prevention Agency, Wang, Asthma, Child, Cough, Society, Calcium, Cell, ORAI1, American Society of Hematology, Allergen, Membrane protein, St. Jude Children's Research Hospital, Immunoglobulin E, NYU Langone Health, Wheeze, Acute pancreatitis, Eosinophil, Gene expression, Experimental pathology, Disease, CRAC, Cytokine, Pain scale, MD, Doctor of Philosophy, Bernard Levin, COVID-19, Vaccine, Pharmaceutical industry, Science, T helper cell, New York University

Blocking signals sent through this channel with an investigational new drug called a CRAC channel inhibitor had a similar effect.

Key Points: 
  • Blocking signals sent through this channel with an investigational new drug called a CRAC channel inhibitor had a similar effect.
  • Allergic asthma is characterized by increased type 2 (T2) inflammation, which involves a subset of T cells called T helper (Th) 2 cells, say the study authors.
  • Without calcium entering through CRAC channels, T cells are unable to become Th2 cells and produce the cytokines that cause allergic asthma, the authors say.
  • "This suggests CRAC channel inhibition as a promising, potential future treatment approach for allergic airway disease."

DEINOVE to present data on DNV3837 at the ESCMID/ASM conference in Dublin

Retrieved on: 
Wednesday, October 5, 2022
CDC, Constipation, Epithelium, White Blood Cells, Infection, Clostridioides difficile (bacteria), Feces, QIDP, Virulence, Toxic megacolon, Diarrhea, CDI, Patient, Clostridioides difficile infection, Perforated ulcer, Collection, GI, Subclinical infection, Centers for Disease Control and Prevention, ISIN, Center, Vomiting, Company, Physiology, Gram-positive bacteria, Blood, Disease, Incidence, Bacteria, Recurrence, Vancomycin, Ileus, Intubation, Heart, Global health, FDA, Pharmaceutical industry, Vaccine, Dietary supplement, Antibiotics, Clostridioides

Preclinical and clinical data show that the prodrug DNV3837 is rapidly converted to DNV3681 in vivo and that the active drug mostly concentrates in the GI tract.

Key Points: 
  • Preclinical and clinical data show that the prodrug DNV3837 is rapidly converted to DNV3681 in vivo and that the active drug mostly concentrates in the GI tract.
  • The diarrhea episodes improved after 6 days of treatment and came back to normal 10 days after treatment after a transient constipation period.
  • Georges Gaudriault, Chief Scientific Officer of DEINOVE who attended the ESCMID/ASM conference in Dublin specifies: The use of DNV3837 is a potential paradigm shift.
  • Located at the heart of the Euromedecine park in Montpellier, DEINOVE has been listed on EURONEXT GROWTH (ALDEI - code ISIN FR0010879056) since 2010.