Magnetic nanoparticles

NIH SBIR Grant Awarded to Accelerate Magnetic Particle Imaging in Cancer Immunology

Retrieved on: 
Monday, September 30, 2019
Medicine, Medical specialties, Branches of biology, Imaging, Magnetic particle imaging, Medical physics, Medical imaging, Inflammation, Combinatorial ablation and immunotherapy, Magnetic nanoparticles

During the twelve-month project, entitled "Development of a commercial Magnetic Particle Imaging platform for the detection and quantification of localized inflammation in cancer," Magnetic Insight will develop new cancer immunology tools for visualizing inflammation.

Key Points: 
  • During the twelve-month project, entitled "Development of a commercial Magnetic Particle Imaging platform for the detection and quantification of localized inflammation in cancer," Magnetic Insight will develop new cancer immunology tools for visualizing inflammation.
  • Localized inflammation is an attractive diagnostic imaging target for a variety of diseases and conditions, including traumatic injury, stroke, auto-immune diseases, and cancer.
  • "Magnetic particle imaging is enabling new insights into cancer immunology by tracking therapeutic cells, identifying inflammation due to immune activation, and with targeted hyperthermia.
  • Magnetic Particle Imaging (MPI) is an ultrasensitive, safe, and quantitative technology built on high-contrast detection of iron-oxide nanoparticles.

New Momentum Magnetic Particle Imaging Scanner to be installed in Baltimore

Retrieved on: 
Thursday, August 29, 2019
Imaging, Magnetic particle imaging, Medical imaging, MPI, Optics, Vision, Recording, Magnetic nanoparticles

BALTIMORE, Aug. 29, 2019 /PRNewswire/ --A Magnetic Particle Imaging (MPI) scanner will be installed in The F.M.

Key Points: 
  • BALTIMORE, Aug. 29, 2019 /PRNewswire/ --A Magnetic Particle Imaging (MPI) scanner will be installed in The F.M.
  • Kirby Imaging Center, led by Dr. van Zijl at Kennedy Krieger Institute will house the MOMENTUM MPI system, developed by Magnetic Insight.
  • "Magnetic particle imaging lies at the intersection of nanotechnology and medical imaging, producing potentially life-saving diagnostic capabilities complimentary to other current medical imaging technologies.
  • Magnetic Particle Imaging (MPI) is an ultrasensitive, safe, and quantitative technology built on high-contrast detection of iron-oxide nanoparticles.

REDBUD LABS STR™ Microfluidic Chip Outperforms Magnetic Beads in Affinity-capture Study

Retrieved on: 
Thursday, August 8, 2019
Magnetic nanoparticles, Magnetism, Red Bud, Electronics cartridge

STR was compared against the gold standard method, magnetic beads, in affinity capture of 1 micron targets.

Key Points: 
  • STR was compared against the gold standard method, magnetic beads, in affinity capture of 1 micron targets.
  • In the study, a one-minute STR protocol captured three times as many targets as a 30-minute on-cartridge magnetic bead assay, showing STR was simultaneously 30x faster and 3x more efficient.
  • "Anyone developing a sample-to-answer test needs to grapple with just how poorly magnetic beads can perform on-cartridge," said Richard Spero, CEO of Redbud Labs.
  • "This study reveals the power of Redbud Posts," said Dr. Jay Fisher, Vice President of R&D at Redbud Labs.

Otomagnetics Engaged Frontage Laboratories, Inc. For c-GMP Manufacturing of Otomagnetics Magnetic Drug Delivery Formulation

Retrieved on: 
Sunday, June 23, 2019
Medicine, Clinical medicine, Health, Audiology, Magnetic nanoparticles, Magnetism, Ear, Otitis media, Non-invasive procedure, Magnetic drug delivery

Magnetic delivery to the middle ear may provide a non-invasive treatment for recurrent or chronic child middle ear infections.

Key Points: 
  • Magnetic delivery to the middle ear may provide a non-invasive treatment for recurrent or chronic child middle ear infections.
  • The strategic and cost effective engagement between Otomagnetics and Frontage Laboratories is enabling the development of magnetic nanoparticles carrying two drugs for the non-invasive treatment of middle ear infection using Otomagnetics' proprietary magnetic delivery system.
  • Engaging with Frontage Laboratories strengthens Otomagnetics' preclinical manufacturing ability, which would facilitate IND enabling studies," says Abhita Batra, CEO of Otomagnetics.
  • "We are excited to engage Otomagnetics to help manufacture their novel magnetic drug delivery product, which could enable treatment of multiple conditions," says Dr. Song Li, CEO of Frontage Laboratories.

Transporting the Light Killers: NUST MISiS and MIREA-Russian Technological University Collaborate to Create a Unique Tandem of Organic Molecules and Nanoparticles to Fight Cancer

Retrieved on: 
Thursday, December 13, 2018
Medicine, Health, Light therapy, Photochemistry, Medical physics, Cancer treatments, Laser medicine, Photodynamic therapy, Photosensitizer, Treatment of cancer, Therapy, Magnetic nanoparticles

"The photodynamic therapy is a cancer treatment method that uses a combination of special preparations-photosensitizers and light with waves of a certain length.

Key Points: 
  • "The photodynamic therapy is a cancer treatment method that uses a combination of special preparations-photosensitizers and light with waves of a certain length.
  • The photosensitizers tend to accumulate in the tumor and when exposed to light with certain wavelengths they produce a special form of oxygen that destroys cancer cells.
  • In addition to destroying cancer cells, photodynamic therapy destroys cancer in two other ways.
  • The NUST MISIS research team has solved this problem with an innovative drug that includes bacteriochlorin molecules and magnetic nanoparticles.

Palacký University Olomouc: Czech Scientists have Discovered a New Way to Control the Magnetic and Electronic Properties of Molecules

Retrieved on: 
Tuesday, September 4, 2018
Chemistry, Emerging technologies, Nature, Universe, Monolayers, Graphene, Potential applications of graphene, Covalent bond, Molecule, Magnetic nanoparticles, Carbon nanotube

Commonly, a change in the electronic configuration of molecules can be induced by application of external stimuli, such as light, temperature, pressure, and magnetic field.

Key Points: 
  • Commonly, a change in the electronic configuration of molecules can be induced by application of external stimuli, such as light, temperature, pressure, and magnetic field.
  • Czech scientists have instead developed a revolutionary way to use weak non-covalent interactions of molecules with the surface of chemically modified graphene.
  • "The possibility of modifying the electronic structure of single molecules and their magnetic properties has been of interest to researchers for several decades because of its great application potential.
  • 'The electronic structure influences not only the magnetic but also the optical, catalytic, electrical, and biological properties of molecules.

National Institutes of Health Awards Magnetic Insight with a $1.5M Phase II SBIR grant to support the first commercial multimodal preclinical magnetic particle imaging system with sub-millimeter resolution, nano-molar sensitivity, and integrated CT

Retrieved on: 
Wednesday, August 1, 2018
Imaging, Magnetic particle imaging, Magnetic nanoparticles, Nanoparticle, Iron oxide nanoparticle, MPI, Chemistry, Physics, Medical imaging, Suh Jin-suck

This grant will provide $1.5 million over two years for Magnetic Insight's continued development of the Momentum MPI scanner.

Key Points: 
  • This grant will provide $1.5 million over two years for Magnetic Insight's continued development of the Momentum MPI scanner.
  • Magnetic Insight was founded to commercialize Magnetic Particle Imaging (MPI), a new imaging modality that directly detects magnetic nanoparticle tracers.
  • Funding was used to develop a working prototype of the first field free line magnetic particle imaging system for commercialization.
  • Magnetic Particle Imaging (MPI) is an ultrasensitive, safe and quantitative technology, harnessing high contrast detection of iron oxide nanoparticles.

Science and Technology of Advanced Materials Research: Comprehensive Review on Biomedical Applications of Magnetic Iron Oxide Nanoparticles Wins STAM Best Paper Award 2017

Retrieved on: 
Friday, January 12, 2018
Nanoparticle, Magnetic nanoparticles, Science and Technology of Advanced Materials, National Institute for Materials Science, Stam, Iron oxide nanoparticle, Wuhan, Academic publishing, Publishing, Materials science

Wei Wu of Wuhan University, China, shares his insights into magnetic nanoparticles for medical applications and his thoughts on winning the Science and Technology of Advanced Materials (STAM) Best Paper Award 2017.

Key Points: 
  • Source: Science and Technology of Advanced Materials (STAM) Headquarter Office, National Institute for Materials Science (NIMS)

    Wei Wu of Wuhan University, China, shares his insights into magnetic nanoparticles for medical applications and his thoughts on winning the Science and Technology of Advanced Materials (STAM) Best Paper Award 2017.

  • Now, Wei Wu and colleagues at Wuhan University, China, are building on the long history of innovative biomedical applications of iron oxide nanoparticles.
  • Surface functionalized magnetic iron oxide nanoparticles are being examined from both the fundamental and practical perspectives, especially in bio-applications, says Wu.
  • The review for the Science and Technology of Advanced Materials (STAM) contains the latest findings on functionalizing strategies, synthesis, and bio-applications of iron oxide NPs.