Proceedings of the National Academy of Sciences of the United States of America

Vast majority of U.S. adults believe dental coverage is an important part of overall wellness, according to Delta Dental report

Retrieved on: 
Thursday, September 28, 2023

Delta Dental commissioned the research, which included more than 2,000 U.S. adults and parents of children 12 and under.

Key Points: 
  • Delta Dental commissioned the research, which included more than 2,000 U.S. adults and parents of children 12 and under.
  • "This year's report underscores the critical role of dental insurance in supporting whole person health," said James W. Hutchison, President & CEO, Delta Dental Plans Association.
  • Key findings from the 2023 report include:
    The report finds 86% of adults agree that having dental coverage allows for good overall health.
  • A vast majority of adults (82%) believe that dental insurance is an essential part of overall wellness.

ZAGG Introduces XTR3 Screen Protection and Graphene-Infused Cases for iPhone 15 Range of Smartphones

Retrieved on: 
Tuesday, September 12, 2023

SALT LAKE CITY, Sept. 12, 2023 (GLOBE NEWSWIRE) -- ZAGG ®, the global leader in accessories and technologies that empower mobile lifestyles, today announced XTR3 screen protection and protective cases infused with Graphene, one of the strongest materials on earth.1 The new screen protectors and cases are available for iPhone 15 , iPhone 15 Plus , iPhone 15 Pro , and iPhone 15 Pro Max .

Key Points: 
  • SALT LAKE CITY, Sept. 12, 2023 (GLOBE NEWSWIRE) -- ZAGG ®, the global leader in accessories and technologies that empower mobile lifestyles, today announced XTR3 screen protection and protective cases infused with Graphene, one of the strongest materials on earth.1 The new screen protectors and cases are available for iPhone 15 , iPhone 15 Plus , iPhone 15 Pro , and iPhone 15 Pro Max .
  • Glass XTR3 also includes an anti-dust adhesive that installs smoothly over most dust, so it disappears on your screen.
  • “ZAGG screen protectors and cases exist where strength meets innovation and redefine the meaning of mobile phone protection,” said Brad Bell, senior vice president of global marketing for ZAGG.
  • 1 selling brand for smartphone screen protection in the U.S. and has set the industry standard for screen protection.

Positive parenting can help protect against the effects of stress in childhood and adolescence, new study shows

Retrieved on: 
Monday, July 10, 2023

The big idea

Key Points: 
  • The big idea
    Warm and supportive parenting may buffer against the effects of stress during childhood and adolescence.
  • Positive parenting includes a range of warm and supportive techniques such as providing praise for doing something well, emotional support and affection.
  • As a first step, we explored whether positive parenting protected against a connection between childhood stress and behavioral problems in children.
  • However, we found that children’s perception of having received positive, supportive parenting served as a buffer against the biological effects of stress.

Cognigenics' Intranasal CRISPR Delivery Bypasses Blood-Brain Barrier; Potential Breakthrough Therapeutic

Retrieved on: 
Thursday, June 22, 2023

Cognigenics CEO John L. Mee announces breakthrough results from an animal study published today in PNAS Nexus.

Key Points: 
  • Cognigenics CEO John L. Mee announces breakthrough results from an animal study published today in PNAS Nexus.
  • The findings point to the potential of non-invasively delivering neuromodulating gene therapies to the brain for chronic mental health conditions using adeno-associated viruses introduced intranasally.
  • The method requires two delivery vectors because of the limited cargo capacity of the viruses.
  • Each virus was modified using Cognigenics' proprietary CRISPR gene-editing technology.

High-frequency Electrical Stimulation Helps Reduce Inflammation, Pain in New Feinstein Institutes Study

Retrieved on: 
Wednesday, October 5, 2022

And while pain is an important defense mechanism to protect the body and promote healing, chronic pain can be debilitating.

Key Points: 
  • And while pain is an important defense mechanism to protect the body and promote healing, chronic pain can be debilitating.
  • The research, led by Feinstein Institutes Sangeeta Chavan, PhD , showed in preclinical mice models that HFES inhibits neuroinflammatory mediator release by sensory neurons, called nociceptors, to reduce pain.
  • For your body to feel pain, neurons release molecules that kickstart the bodys immune response causing inflammation and pain.
  • We now have a better understanding as to why high-frequency stimulation helps attenuate inflammation and associated pain.

Feinstein Institutes Researchers Identify Potential Drug to Treat Sepsis

Retrieved on: 
Monday, August 29, 2022

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20220829005673/en/
    Dr. Matthew D. Taylor, instructor in the Institute of Molecular Medicine at the Feinstein Institutes is co-principal investigator of the study.
  • (Credit: Feinstein Institutes)
    Sepsis is a common and fatal condition when the bodys regulatory control of the immune response to an infection is lost.
  • Researchers worldwide are beginning to unravel the underlying mechanisms of sepsis, said Kevin J. Tracey, MD , president and CEO of the Feinstein Institutes.
  • The Feinstein Institutes for Medical Research is the home of the research institutes of Northwell Health, the largest health care provider and private employer in New York State.

What Makes Omicron More Infectious Than Other COVID-19 Variants

Retrieved on: 
Wednesday, July 20, 2022

SAN FRANCISCO, July 20, 2022 /PRNewswire/ -- As the Omicron variant of SARS-CoV-2 spread rapidly around the globe earlier this year, researchers at Gladstone Institutes, UC Berkeley, and the Innovative Genomics Institute used virus-like particles to identify which parts of the virus are responsible for its increased infectivity and spread.

Key Points: 
  • Compared to other variants, it has also caused more breakthrough infectionsin people previously infected with or fully vaccinated against COVID-19.
  • Scientists can also engineer new virus-like particles much faster than they can grow new variants of the live virus to study.
  • Omicron mutations in the spike protein, they discovered, made virus-like particles twice as infectious as those with the ancestral spike protein.
  • "But it also means that it could be possible for Omicron to evolve to be even more infectious if those brakes are lifted."

ROME Therapeutics Announces Publication of First Crystal Structure of a Human Endogenous Reverse Transcriptase in PNAS

Retrieved on: 
Thursday, June 30, 2022

ROME Therapeutics , a biotechnology company harnessing the power of the dark genome for drug development, today announced a new publication in The Proceedings of the National Academy of Sciences (PNAS) which describes the first-ever X-ray crystallography structure of an endogenous reverse transcriptase specifically human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT).

Key Points: 
  • ROME Therapeutics , a biotechnology company harnessing the power of the dark genome for drug development, today announced a new publication in The Proceedings of the National Academy of Sciences (PNAS) which describes the first-ever X-ray crystallography structure of an endogenous reverse transcriptase specifically human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT).
  • A significant portion of the human genome is made up of endogenous retroviruses, which are associated with a range of serious diseases, including cancer.
  • In this publication, we describe for the first time the crystal structure of an endogenous reverse transcriptase, one known as HERV-K RT, and show that it has remarkable similarities to HIV RT, a well-known tractable drug target, said Dennis Zaller, Ph.D., Chief Scientific Officer of ROME.
  • Similarly, deeper insights into human endogenous RT could pave the way toward a new class of therapies for cancer and other serious diseases.

New Delta Dental report finds many are unaware of connection between poor oral health and serious medical conditions (but 9 in 10 want to learn more)

Retrieved on: 
Thursday, May 5, 2022

OAK BROOK, Ill., May 5, 2022 /PRNewswire/ -- Today, Delta Dental released the 2022 State of America's Oral Health and Wellness Report, a nationwide analysis of consumer opinions and behaviors relating to oral health.

Key Points: 
  • OAK BROOK, Ill., May 5, 2022 /PRNewswire/ -- Today, Delta Dental released the 2022 State of America's Oral Health and Wellness Report, a nationwide analysis of consumer opinions and behaviors relating to oral health.
  • However, the research finds that many are unaware of how oral health and overall health are connected, as a significant number of people were unable to recognize the medical conditions that are linked to poor oral health, including strokes (38%), high blood pressure (37%) and diabetes (36%).
  • The promising news is 9 in 10 (90%) adults are interested in learning about oral health's critical connection to overall health.
  • New research finds 9 in 10 U.S. adults want to learn about oral health's critical connection to overall health.

Seer Announces Publication of Seminal Study Demonstrating Superior Performance of Technology Platform for Deep, Unbiased, Precise, Scalable Proteomics in the Proceedings of the National Academy of Sciences

Retrieved on: 
Monday, March 14, 2022

These are exciting times for the field, and were at a watershed moment where our access to deep, unbiased proteomics information at scale is no longer constrained.

Key Points: 
  • These are exciting times for the field, and were at a watershed moment where our access to deep, unbiased proteomics information at scale is no longer constrained.
  • In this study, Seer demonstrates superior performance of the technology platform underlying the Proteograph Product Suite.
  • The performance of the Proteograph Product Suite uniquely enables population-scale unbiased studies where a large number of protein variants may be discovered.
  • This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended.