PPI

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptake is Significantly More Impaired than Previously Understood

Retrieved on: 
onsdag, november 8, 2023

Xspray has demonstrated that in the DASYNOC CO-PPI Study, DASYNOC’s uptake into blood was not affected 10 hours after taking omeprazole (107 % of intended AUC0-24h and 86% of intended Cmax).

Key Points: 
  • Xspray has demonstrated that in the DASYNOC CO-PPI Study, DASYNOC’s uptake into blood was not affected 10 hours after taking omeprazole (107 % of intended AUC0-24h and 86% of intended Cmax).
  • However, in the SPRYCEL CO-PPI Study, the uptake of SPRYCEL was significantly reduced 10 hours after taking omeprazole (only 12% of the intended AUC0-24h and 4% of the intended Cmax).
  • “We recently published that CML patients, concomitantly treated with TKIs and PPIs, are at a statistically significant 3.5-fold increased risk of death.
  • SPRYCEL was approved in 2006 by the FDA and is the market leading branded product that revolutionized the treatment of CML.

Phathom Pharmaceuticals Announces FDA Approval of VOQUEZNA® (vonoprazan) Tablets for the Treatment of Erosive GERD and Relief of Heartburn Associated with Erosive GERD in Adults

Retrieved on: 
onsdag, november 1, 2023

“Erosive GERD can be extremely painful and often has a significant impact on patients.

Key Points: 
  • “Erosive GERD can be extremely painful and often has a significant impact on patients.
  • VOQUEZNA 20 mg also demonstrated non-inferiority to lansoprazole 30 mg in the mean percentage of 24-hour heartburn free days over the healing period.
  • In addition, VOQUEZNA 10 mg was evaluated as a secondary endpoint for relief of heartburn in Erosive GERD patients and demonstrated non-inferiority to lansoprazole 15 mg over six months.
  • ET to discuss the FDA approval and the Company’s U.S. commercialization plans for Erosive GERD and H. pylori infection.

BICMD Expands Services under New Clinical Advisors

Retrieved on: 
måndag, oktober 30, 2023

Drs Brigham and Greditzer will oversee new service lines for BICMD: Impairment Ratings and Age of Injury Radiology Reports, respectively.

Key Points: 
  • Drs Brigham and Greditzer will oversee new service lines for BICMD: Impairment Ratings and Age of Injury Radiology Reports, respectively.
  • The addition of these services reflects the commitment to assisting enterprise clients navigate complex medical claims handling and enabling better outcomes for both employers and injured workers.
  • Dr. Tate Greditzer, the leading MSK-trained radiologist for the National Basketball Players Association and the N.Y. Mets, will provide and oversee these services for BICMD.
  • BICMD is a trusted provider of expert medical opinions, offering a wide range of medical consulting solutions to support businesses.

New PPI Report Reveals Top 25 Companies Investing in America with Amazon Leading the List

Retrieved on: 
fredag, oktober 27, 2023

The report, " Investment Heroes 2023 ," published annually since 2012, analyzes publicly available data to identify the top 25 U.S. companies investing in America, powering job growth, and raising living standards.

Key Points: 
  • The report, " Investment Heroes 2023 ," published annually since 2012, analyzes publicly available data to identify the top 25 U.S. companies investing in America, powering job growth, and raising living standards.
  • Eight of the top 10 companies on this year's ranking are in the technology, broadband, or ecommerce industries.
  • "Since our first Investment Heroes report in 2012, the companies featured on the list have drastically changed.
  • "The 2023 Investment Heroes list and analysis show it is important to recognize not only what companies are investing in America, but what companies are investing in workers," said Jordan Shapiro.

Serious Concerns About Frequent Heartburn Medications Spurs Demand for Healthy Alternatives

Retrieved on: 
torsdag, oktober 26, 2023

VENICE, Fla., Oct. 26, 2023 /PRNewswire/ -- As consumer interest in heartburn solutions reaches unprecedented levels, Enzymedica, a trusted leader in digestive health, introduces a range of all-natural, healthy alternatives for occasional heartburn and indigestion relief. This move comes in response to the recent revelation of a study linking long-term usage of Proton Pump Inhibitors (PPIs) to potential health risks, including dementia. With a commitment to providing safe and effective solutions, Enzymedica offers consumers a variety of options that not only relieve symptoms of occasional heartburn resulting from food and diet choices, but also promote overall digestive wellness.

Key Points: 
  • VENICE, Fla., Oct. 26, 2023 /PRNewswire/ -- As consumer interest in heartburn solutions reaches unprecedented levels, Enzymedica , a trusted leader in digestive health, introduces a range of all-natural, healthy alternatives for occasional heartburn and indigestion relief.
  • The heartburn solutions category has faced stagnation due to a lack of innovation, concerns about drug side effects and confusion surrounding the frequent, long-term usage of PPIs and other acid inhibitors.
  • The recent study shedding light on potential health risks associated with PPIs has left consumers seeking trustworthy alternatives that prioritize their well-being.
  • These products offer consumers a reliable and convenient way to address their occasional heartburn concerns with natural, science-backed solutions.

Rayleigh Vision Unveils Innovative Repairable MicroLED Technology

Retrieved on: 
fredag, oktober 20, 2023

The company is introducing a breakthrough in MicroLED technology with the unveiling of repairable pixel architecture, aimed at enhancing display longevity while reducing maintenance costs.

Key Points: 
  • The company is introducing a breakthrough in MicroLED technology with the unveiling of repairable pixel architecture, aimed at enhancing display longevity while reducing maintenance costs.
  • To view an enhanced version of this graphic, please visit:
    Rayleigh Vision is making advancements in the field of display technology through its work on MicroLED innovations.
  • A notable feature of Rayleigh Vision's technology is its repairable pixel architecture.
  • By consistently investing in the development and protection of new patents, Rayleigh Vision aims to solidify its position as a forerunner in the MicroLED market.

IDTechEx Asks, Will LCDs Be Replaced in VR

Retrieved on: 
onsdag, september 27, 2023

It predicts the VR display market to grow at a CAGR of 7.5% to 2034, with innovation in display technology driving this growth ahead of the whole VR market.

Key Points: 
  • It predicts the VR display market to grow at a CAGR of 7.5% to 2034, with innovation in display technology driving this growth ahead of the whole VR market.
  • As this problem was solved, VR headset designers saw the other advantages of LCDs, as well as their lower cost.
  • The display industry clearly views this technology as extremely important, and IDTechEx expects OLED-on-Si to be a leading VR display technology by 2034.
  • As the VR landscape evolves, OLED-on-Si and other emerging technologies, including micro-LED, are expected to reshape the VR display landscape, eventually ending LCDs' current reign.

IDTechEx Asks, Will LCDs Be Replaced in VR

Retrieved on: 
onsdag, september 27, 2023

It predicts the VR display market to grow at a CAGR of 7.5% to 2034, with innovation in display technology driving this growth ahead of the whole VR market.

Key Points: 
  • It predicts the VR display market to grow at a CAGR of 7.5% to 2034, with innovation in display technology driving this growth ahead of the whole VR market.
  • As this problem was solved, VR headset designers saw the other advantages of LCDs, as well as their lower cost.
  • The display industry clearly views this technology as extremely important, and IDTechEx expects OLED-on-Si to be a leading VR display technology by 2034.
  • As the VR landscape evolves, OLED-on-Si and other emerging technologies, including micro-LED, are expected to reshape the VR display landscape, eventually ending LCDs' current reign.

Zafin™ Unveils Zafin Studio

Retrieved on: 
tisdag, september 19, 2023

Built on the foundation of Zafin’s proven end-to-end product and pricing platform architecture, Zafin Studio is a consultative framework and methodology that integrates customer-centric design principles with actionable market and customer insights provided by Zafin’s Proposition Canvas, Product and Pricing Index (PPI), and Product Explorer.

Key Points: 
  • Built on the foundation of Zafin’s proven end-to-end product and pricing platform architecture, Zafin Studio is a consultative framework and methodology that integrates customer-centric design principles with actionable market and customer insights provided by Zafin’s Proposition Canvas, Product and Pricing Index (PPI), and Product Explorer.
  • The powerful combination of the Zafin platform plus modeling techniques and tools enables the creation and delivery of tailored customer propositions that closely match customer preferences.
  • Zafin Product and Pricing Index will be available in private preview in Q4 2023, Zafin Product Explorer will be available in private preview in Q1 2024, and Zafin Proposition Canvas will be in private preview in Q2 2024.
  • Request a consultation for Zafin Studio today or book a meeting with the Zafin team during the week of Sibos to learn more.

Incode Technologies and Aristotle Reinvent Identity and Age Verification in the Gambling Sector

Retrieved on: 
måndag, september 18, 2023

SAN FRANCISCO, Sept. 18, 2023 /PRNewswire/ -- Incode Technologies Inc., a leading provider of world-class identity verification and authentication solutions for global enterprises, today announced a partnership with Aristotle Integrity, a leader in identity, KYC and anti-fraud services.

Key Points: 
  • Now, Aristotle can offer the Incode-powered Integrity AutoDoc solution to its customers across the iGaming and Sportsbook sector.
  • With this revolutionary partnership, Aristotle has integrated Incode into Integrity AutoDoc, part of Aristotle's suite of identity and age verification solutions.
  • Aristotle also operates in other sectors, including crypto, financial services, social media, and adult age verification.
  • "The challenges of compliance expenses, data responsibility, and the rise of age verification concerns underscore the difficulties legacy identity systems pose for iGaming and gambling," said Ricardo Amper, CEO and Founder of Incode.