Spark Therapeutics

Crinetics Pharmaceuticals Adds Board Member with Global Rare Disease Expertise with Appointment of Rogério Vivaldi Coelho, M.D., M.B.A.

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среда, января 5, 2022

Dr. Vivaldi comes to Crinetics with over two decades of experience as a physician and industry executive with deep expertise commercializing pharmaceuticals, especially those treating rare and orphan diseases, in the U.S. and globally.

Key Points: 
  • Dr. Vivaldi comes to Crinetics with over two decades of experience as a physician and industry executive with deep expertise commercializing pharmaceuticals, especially those treating rare and orphan diseases, in the U.S. and globally.
  • Dr. Vivaldi is currently the president and chief executive officer of Sigilon Therapeutics, Inc., where he also serves as a member of the company's board of directors.
  • While each rare disease impacts only a small number of people, they collectively affect an estimated 25-30 million Americans.
  • Crinetics Pharmaceuticals is a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors.

Intellia Therapeutics Appoints Derek Hicks as Chief Business Officer

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понедельник, декабря 20, 2021

CAMBRIDGE, Mass., Dec. 20, 2021 (GLOBE NEWSWIRE) -- Intellia Therapeutics, Inc. (NASDAQ: NTLA), a leading genome editing company focused on developing curative therapeutics using CRISPR/Cas9 technology both in vivo and ex vivo, today announced the appointment of Derek Hicks to a newly created position as Executive Vice President, Chief Business Officer.

Key Points: 
  • CAMBRIDGE, Mass., Dec. 20, 2021 (GLOBE NEWSWIRE) -- Intellia Therapeutics, Inc. (NASDAQ: NTLA), a leading genome editing company focused on developing curative therapeutics using CRISPR/Cas9 technology both in vivo and ex vivo, today announced the appointment of Derek Hicks to a newly created position as Executive Vice President, Chief Business Officer.
  • Mr. Hicks joins Intellia with more than 25 years of combined business, leadership and biotechnology experience, having most recently served as Head of Business Development at Spark Therapeutics.
  • I am thrilled to welcome Derek to Intellias executive team as we enter the next chapter in our evolution, said Intellia President and Chief Executive Officer John Leonard, M.D.
  • Intellia Therapeutics, a leading clinical-stage genome editing company, is developing novel, potentially curative therapeutics using CRISPR/Cas9 technology.

Spark Therapeutics to Invest $575M in New 500k Square Foot State-of-the-Art Gene Therapy Innovation Center on Drexel’s University City Campus

Retrieved on: 
пятница, декабря 17, 2021

PHILADELPHIA, Dec. 17, 2021 (GLOBE NEWSWIRE) -- Spark Therapeutics, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY) and a fully integrated, commercial gene therapy company dedicated to challenging the inevitability of genetic disease, today announced plans to invest an initial $575M in the creation of a new, state-of-the-art gene therapy innovation center on Drexel University’s campus in the heart of Philadelphia’s University City neighborhood. Through a 99-year ground lease of Drexel University’s F Lot, the new center will be located at the intersection of 30th and Chestnut Streets and will create opportunities for collaboration with Drexel University and Philadelphia’s booming life sciences community. Terms of the ground lease, including financial terms, were not disclosed.

Key Points: 
  • Sparks gene therapy innovation center creates endless opportunities for collaboration, talent development and research investment, and were proud to make a long-term commitment to the city and add Philadelphia to the Roche map.
  • We are proud to partner with Spark Therapeutics in advancing life sciences research and innovation in University City, said John Fry, president, Drexel University.
  • Construction of Sparks new gene therapy innovation center is anticipated to begin in the fourth quarter of 2022.
  • Founded in 2013, Spark Therapeutics is the first company in the U.S. to receive FDA approval of a gene therapy for a genetic disease.

SparingVision Strengthens Leadership Team with the Appointment of Dr Mehdi Gasmi as Chief Operating Officer

Retrieved on: 
четверг, декабря 9, 2021

Paris, December 9, 2021 SparingVision, a genomic medicine company developing vision-saving treatments for ocular diseases, today announces the appointment of Dr Mehdi Gasmi, PhD, as Chief Operating Officer (COO), as well as other senior appointments, further strengthening the SparingVision team.

Key Points: 
  • Paris, December 9, 2021 SparingVision, a genomic medicine company developing vision-saving treatments for ocular diseases, today announces the appointment of Dr Mehdi Gasmi, PhD, as Chief Operating Officer (COO), as well as other senior appointments, further strengthening the SparingVision team.
  • Mehdi Gasmi is a seasoned executive with over 25 years of experience across the gene therapy drug development field, including in ophthalmology indications.
  • Dr Mehdi Gasmi, PhD, commented: SparingVisions disruptive approach to combat retinal disease is inspiring and I am excited to be joining such a visionary team.
  • SparingVision is also delighted to announce the appointments of Dr Raffaella Toso, PhD, as VP Corporate Development and Florence Paliargues, Pharm.

AnaptysBio Announces Appointment of Daniel Faga to Board of Directors

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понедельник, ноября 29, 2021

SAN DIEGO, Nov. 29, 2021 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company developing first-in-class antibody product candidates focused on emerging immune control mechanisms applicable to inflammation and immuno-oncology indications, today announced the appointment of Mr. Daniel Faga to the companys Board of Directors.

Key Points: 
  • SAN DIEGO, Nov. 29, 2021 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company developing first-in-class antibody product candidates focused on emerging immune control mechanisms applicable to inflammation and immuno-oncology indications, today announced the appointment of Mr. Daniel Faga to the companys Board of Directors.
  • His unique strategic vision is an exciting addition to our Board of Directors and we look forward to having Dans perspective as AnaptysBio continues to advance multiple wholly-owned clinical and preclinical first-in-class therapeutic antibody programs.
  • Mr. Faga commented, AnaptysBio has an impressive track-record of innovating novel therapeutics and is financially well-positioned to drive potentially transformative medicines over the next several years.
  • AnaptysBio is a clinical-stage biotechnology company developing first-in-class antibody product candidates focused on unmet medical needs in inflammation.

Spark Therapeutics Updated SPK-8011 Data from Phase 1/2 Study Shows Multi-Year, Durable Factor VIII (FVIII) Expression that Significantly Reduced Bleeding in Hemophilia A Patients

Retrieved on: 
среда, ноября 17, 2021

The study found that, at a median efficacy follow-up of 33.4 months (range, 3.7-47.6), 16 of 18 study participants had sustained factor VIII (FVIII), which permitted prophylaxis cessation and reduction in bleeding episodes.

Key Points: 
  • The study found that, at a median efficacy follow-up of 33.4 months (range, 3.7-47.6), 16 of 18 study participants had sustained factor VIII (FVIII), which permitted prophylaxis cessation and reduction in bleeding episodes.
  • As previously reported, two participants lost all FVIII expression due to an anti-AAV capsid cellular immune response, unresponsive to immunosuppression.
  • The current standard of care for hemophilia A requires recurrent intravenous infusions of either plasma-derived or recombinant factor VIII to control and prevent bleeding episodes.
  • At Spark, a member of the Roche Group, we see the path to a world where no life is limited by genetic disease.

Kaleido Biosciences to Appoint Dr. Alison Long as Chief Medical Officer

Retrieved on: 
среда, ноября 10, 2021

Additionally, she will lead our medical affairs team as well as support translational microbiome research and the development of further new drug development candidates.

Key Points: 
  • Additionally, she will lead our medical affairs team as well as support translational microbiome research and the development of further new drug development candidates.
  • I am honored to be joining this talented team at Kaleido during a pivotal stage of growth for the Company, said Dr. Long.
  • She most recently served as interim Chief Medical Officer and Senior Vice President, Head of Clinical Development at Freeline Therapeutics, and was responsible for the clinical development, clinical operations, medical affairs, and regulatory functions of Freelines development programs.
  • She received her medical degree from the University of Witwatersrand, and Ph.D. in biodefense from George Mason University.

Cabaletta Bio Reports Third Quarter 2021 Financial Results and Provides Business Update

Retrieved on: 
понедельник, ноября 1, 2021

The Company remains on track to submit an IND to the FDA in the fourth quarter of 2021.

Key Points: 
  • The Company remains on track to submit an IND to the FDA in the fourth quarter of 2021.
  • PLA2R-CAART advancing toward clinical development: Cabaletta expects to conduct a pre-IND interaction with the FDA in the fourth quarter of 2021.
  • Dr. Payne is a University of Pennsylvania (Penn) faculty member, scientific collaborator, key advisor, and co-founder of Cabaletta Bio.
  • The University of Pennsylvania may also receive future financial benefit under licenses it has granted to Cabaletta Bio.

Insmed Ranks No. 1 on Science's 2021 Top Biopharma Employers List

Retrieved on: 
четверг, октября 28, 2021

The annual survey polls employees in the global biotech and pharmaceutical industry to determine the 20 best employers, as well as their driving characteristics.

Key Points: 
  • The annual survey polls employees in the global biotech and pharmaceutical industry to determine the 20 best employers, as well as their driving characteristics.
  • "It is an honor to have been recognized as the top company to work for in the biopharmaceutical industry in 2021," said Will Lewis, Chair and Chief Executive Officer of Insmed.
  • The 2021 Top Employers results were based on responses from more than 7,200 individuals across North America (64%), Europe (19%), and Asia/Pacific Rim (11%).
  • Companies that scored especially high on this year's list stood out in the areas of innovative leadership, respect for employees, and social responsibility.

Spark Therapeutics and CombiGene Enter into Exclusive, Global Licensing Agreement for Gene Therapy Candidate CG01

Retrieved on: 
вторник, октября 12, 2021

The agreement provides Spark with the exclusive, worldwide license to develop, manufacture and commercialize CG01.

Key Points: 
  • The agreement provides Spark with the exclusive, worldwide license to develop, manufacture and commercialize CG01.
  • Through our new collaboration and licensing agreement with CombiGene, we will work together leveraging our vast knowledge and experience in gene therapy to address unmet needs for people living with drug-resistant focal epilepsy.
  • CG01 is a unique gene therapy candidate aimed at a large patient population to solve a global need in epilepsy treatment.
  • The Company has signed an exclusive collaboration and licensing agreement for CombiGenes CG01 project with Spark Therapeutics.