Nobel Laureate explains role of G-protein coupled receptors to treat disease in Feinstein Institutes’ Match Lecture

A pioneer in molecular pharmacology, Dr. Lefkowitz has dedicated more than five decades of research to discovering and understanding the function of GPCRs, particularly how to turn off – known as desensitization -- the receptors. These receptors are responsible for the senses of sweet and bitter taste and smell, among many other essential functions. Dr. Lefkowitz’s discoveries have had a significant clinical impact on the development of prescription drugs. More than a third of all prescription drug sales are of those that target the receptors, Dr. Lefkowitz and his team discovered.