Impact of SARS-CoV-2 Infection on Host Gene Expression Across Multiple Tissues at Single Cell Resolution, Upcoming Webinar Hosted by Xtalks
To that end, we have conducted a survey of the effects of SARS-COV-2 infection on host gene expression, at the single cell level, across a wide array of tissues obtained from autopsies of confirmed COVID-19 patients.
TORONTO, Sept. 8, 2021 /PRNewswire-PRWeb/ -- The clinical manifestations of COVID-19 infections are highly variable between individuals and are not localized to the lungs and airway passages as seen with other respiratory viruses. In order to define appropriate therapeutic targets and mitigation strategies for COVID-19 infections, it is important to understand the impact of COVID-19 across a wide variety of organs at the cellular level.
To that end, we have conducted a survey of the effects of SARS-COV-2 infection on host gene expression, at the single cell level, across a wide array of tissues obtained from autopsies of confirmed COVID-19 patients. Tissues from nineteen COVID-19 autopsy patients, including seven from the US and twelve from Europe, were analyzed using single nuclei RNA sequencing (snRNA Seq), along with three non-COVID controls.
Six to eight different organs from each patient were analyzed, including heart, lung, liver, kidney, ileum, colon, spleen, prostate and testes. In all, gene expression analyses were performed on approximately 150 unique tissue specimens. The project required implementation of new experimental workflows and technologies to enable safe handling of the samples.
Join Bruce Wang, Assistant Professor in Residence, Div. of Gastroenterology, UCSF in a live webinar on Thursday, September 23, 2021 at 2pm EDT to hear a presentation of these methods along with the results obtained using tissue processing automation from S2 Genomics detailing the impact of COVID-19 on host gene expression.
For more information, or to register for this event, visit Impact of SARS-CoV-2 Infection on Host Gene Expression Across Multiple Tissues at Single Cell Resolution.
ABOUT S2 GENOMICS, Inc.
S2 Genomics, founded in 2016, is a leading developer of laboratory automation solutions for processing solid tissues for single-cell applications. S2 Genomics' technology platforms integrate advanced fluidics, optics, and biochemistry to produce automated sample preparation solutions for single-cell sequencing and cell biology markets, enabling discovery and innovation in life science research, healthcare, and agriculture. For more information, visit https://S2Genomics.com.
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