NIAID

ATCC Announces Award from National Institute of Allergy and Infectious Diseases to Support Its Preclinical Services for Biopharmaceutical Product Development

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화요일, 11월 7, 2023
Research, Infectious Diseases, Stem Cells, Biotechnology, Health, Pharmaceutical, Other Science, Science, Oncology, National Institute of Allergy and Infectious Diseases, IND, DVM, Indefinite, NIAID, Senior, Private sector, IDIQ, NIH, Infection, Bangladesh Technical Education Board, Investigational New Drug, Pharmaceutical industry, ATCC

ATCC , the world’s premier biological materials management and standards organization, today announced that it has been awarded an Indefinite Delivery/Indefinite Quantity (IDIQ) contract 75N93023D00009 by the National Institute of Allergy and Infectious Diseases ( NIAID ), part of the National Institutes of Health (NIH).

Key Points: 
  • ATCC , the world’s premier biological materials management and standards organization, today announced that it has been awarded an Indefinite Delivery/Indefinite Quantity (IDIQ) contract 75N93023D00009 by the National Institute of Allergy and Infectious Diseases ( NIAID ), part of the National Institutes of Health (NIH).
  • With this contract, ATCC, as a member in the NIAID selected service provider pool, will support NIAID’s Preclinical Services for Biopharmaceutical Product Development in two main areas: the development and validation of analytical assays for product characterization and process development and formulation.
  • “This contract builds upon the work we are already doing with NIAID and several of their divisions, as well as our management of NIAID’s BEI Resources,” said Joseph Leonelli, Ph.D., Senior Vice President and General Manager of ATCC Federal Solutions.
  • “With our expertise and resources, NIAID is better able to more quickly diagnose infectious disease-causing pathogens and toxins, and then strive to develop therapeutic products to treat them.”

Aridis Pharmaceuticals Announces Third Quarter 2023 Financial Results and Business Update

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금요일, 11월 3, 2023
FDA, Research, Sale, National Institute of Allergy and Infectious Diseases, AstraZeneca, Ventilator-associated pneumonia, Antibiotic, Cystic Fibrosis Foundation, VAP, Omicron, NIAID, European Medicines Agency, OTCQB, Tenant, Development, Pharmacokinetics, Priority review, Data monitoring committee, Common stock, QIDP, Pseudomonas aeruginosa, Expense, Nature Communications, COVID-19, Cystic fibrosis, S. aureus, Emory University, EMA, Staphylococcus, Gallium, NIH, Safety, Infection, Patient, Administration, Mab, BLA, Bangladesh Technical Education Board, Respiratory tract, DSMB, ICU, Pharmaceutical industry, Vaccine, Security (finance)

LOS GATOS, Calif., Nov. 03, 2023 (GLOBE NEWSWIRE) -- Aridis Pharmaceuticals, Inc. (OTCQB: ARDS), a biopharmaceutical company focused on the discovery and development of novel anti-infective therapies for treating life-threatening infections, today reported financial and corporate results for its third quarter ended September 30, 2023.

Key Points: 
  • OTCQB companies must be current in their financial reporting and undergo an annual verification and management certification process.
  • We remain optimistic of successful outcomes from these efforts in the coming months,” commented Vu Truong, Ph.D., Chief Executive Officer of Aridis Pharmaceuticals.
  • Due to fair value option valuation of our notes payable, there was no interest expense recorded during the third quarter of 2023.
  • Other Income: Other income increased to $26,000 for the quarter ended September 30, 2023, compared to approximately $23,000 for the quarter ended September 30, 2022.

Aligos Therapeutics Reports Recent Business Progress and Third Quarter 2023 Financial Results

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목요일, 11월 2, 2023
FDA, Research, IND, Principal investigator, Therapy, NIAID, Liver, CHB, MBA, R, NASH, Clinical trial, NIH, Safety, PIPE, Investment, Doctor of Philosophy, SAN, Pharmaceutical industry, Vaccine, G&A

SOUTH SAN FRANCISCO, Calif., Nov. 02, 2023 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in liver and viral diseases, today reported recent business progress and financial results for the third quarter 2023.

Key Points: 
  • SOUTH SAN FRANCISCO, Calif., Nov. 02, 2023 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in liver and viral diseases, today reported recent business progress and financial results for the third quarter 2023.
  • “Over this quarter, we raised approximately $92 million in a private placement financing allowing the advancement of our NASH THR-ß and CHB CAM-E programs.
  • We are proud to have achieved these critical milestones,” noted Lawrence Blatt, Ph.D., MBA, Chairman & CEO of Aligos Therapeutics.
  • The increase in G&A expenses for this comparative period is primarily attributable to an increase in legal and related costs.

Tonix Pharmaceuticals’ Vaccine Candidate, TNX-1800, Selected by NIH/NIAID Project NextGen for Inclusion in Clinical Trials

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목요일, 11월 2, 2023
Monkeypox virus, FDA, National Institute of Allergy and Infectious Diseases, HHS, Food, Therapy, Vaccine, SARS-CoV-2, NIAID, Face, Mpox, Project, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Volunteering, Tonix Pharmaceuticals, Clinical trial, COVID-19, Smallpox, Nextgen, Animal, RPV, NIH, Safety, Office of Inspector General, U.S. Department of Health and Human Services, Infection, Tuberculosis, Bangladesh Technical Education Board

CHATHAM, N.J., Nov. 02, 2023 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP), a biopharmaceutical company with marketed products and a pipeline of development candidates, today announced that the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH), will conduct a Phase 1 clinical trial with TNX-1800 (recombinant horsepox virus, live vaccine),1 Tonix Pharmaceuticals’ vaccine candidate to protect against COVID-19.

Key Points: 
  • Tonix is developing a novel vaccine platform initially targeting COVID-19, smallpox and mpox (monkeypox).
  • The intent is to provide durable protection against severe disease and prevent forward transmission, primarily by eliciting a T-cell immune response.
  • “TNX-1800 will be the first vaccine candidate using our live virus recombinant pox virus (RPV) platform technology to enter clinical trials.
  • NIAID will be conducting clinical trials to evaluate several early-stage vaccine candidates.

New York Blood Center Enterprises Grants Exclusive License to Big Eye Diagnostics for Diagnostic Biomarkers in River Blindness

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수요일, 11월 1, 2023
National Institute of Allergy and Infectious Diseases, WHO, Onchocerciasis, MDA, Biomarker, Infection, NIAID, Research, Laboratory, Disease, World Health Organization, Risk, Mass drug administration, Partnership, Lindsley, Poverty, Onchocerca volvulus, NIH, Diagnosis, Bangladesh Technical Education Board, Pharmaceutical industry, Medical device

NEW YORK, Nov. 01, 2023 (GLOBE NEWSWIRE) -- New York Blood Center Enterprises (NYBCe) announced today it granted an exclusive commercial license to Big Eye Diagnostics for the rights to develop a diagnostic tool for onchocerciasis or river blindness.

Key Points: 
  • NEW YORK, Nov. 01, 2023 (GLOBE NEWSWIRE) -- New York Blood Center Enterprises (NYBCe) announced today it granted an exclusive commercial license to Big Eye Diagnostics for the rights to develop a diagnostic tool for onchocerciasis or river blindness.
  • River Blindness impacts 18 million individuals, with an additional 218 million at risk of contracting the disease.
  • Furthermore, the resulting solution could streamline deployment in the affected geographies, addressing a significant need in the fight against river blindness.
  • "This innovative work from NYBC and NIH provides the necessary foundation to improve diagnosis in a global effort to eliminate river blindness."

Positive Results Announced in Largest Pivotal Phase 3 Trial of a First-in-Class Oral Antibiotic to Treat Uncomplicated Gonorrhea

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수요일, 11월 1, 2023
Health, Infectious Diseases, Clinical Trials, Research, Science, Pharmaceutical, Biotechnology, Grand duchy, Food, Face, VWS, Disease, Gonorrhea, MHLW, Partnership, The Lancet, National Rural Development Partnership, Infection, Nursing care plan, Reproduction, SAMRC, Azithromycin, Hope, Physician, Prevalence, HIV, Ceftriaxone, BMBF, Neisseria gonorrhoeae, University, Therapy, Patient, Food and Drug Administration, Infertility, DFID, Heart, BMG, NIAID, MD, DHSC, AMR, BZ, Clinical trial, World Health Organization, Zoliflodacin, Woman, Multidrug-resistant bacteria, FOPH, South African Medical Research Council, Death, Ministry, Pharmaceutical industry, Vaccine, Medicine

These positive preliminary findings offer hope for patients with this condition, particularly in the face of rising antibiotic resistance to current regimens.

Key Points: 
  • These positive preliminary findings offer hope for patients with this condition, particularly in the face of rising antibiotic resistance to current regimens.
  • It also paves the way for a new research and development model in the global fight against antimicrobial resistance (AMR).
  • Now, the positive results of this landmark Phase 3 trial confirm that zoliflodacin has the potential to tackle the most difficult-to-treat gonorrhea infections.
  • This builds on the critical Phase 2 clinical trial sponsored by the U.S. National Institute of Allergy and Infectious Diseases (NIAID).

Inimmune Collaborates with Boston Children'S Hospital to Develop Novel Adjuvants

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화요일, 10월 24, 2023
Infection, Faculty, Allergic rhinitis, Vaccine, BCH, NIAID, PVP, Boston Children's Hospital, Research, Pediatrics, Messenger, Immunotherapy, NIH, Adjuvant, Hospital, Bangladesh Technical Education Board, MD, Chemistry

MISSOULA, Mont., Oct. 24, 2023 /PRNewswire/ -- Inimmune Corporation, a clinical-stage biotechnology company focused on creating and developing innovative immunotherapeutics, announced that it has entered a research collaboration with Boston Children's Hospital (BCH) to develop novel and innovative small molecule vaccine adjuvants.

Key Points: 
  • MISSOULA, Mont., Oct. 24, 2023 /PRNewswire/ -- Inimmune Corporation, a clinical-stage biotechnology company focused on creating and developing innovative immunotherapeutics, announced that it has entered a research collaboration with Boston Children's Hospital (BCH) to develop novel and innovative small molecule vaccine adjuvants.
  • Inimmune prioritizes research into new classes of adjuvants and immunotherapies for vaccines and stand-alone indications and has a deep pipeline of rapidly advancing programs.
  • "At Inimmune, we continue to identify and develop novel and unique immunotherapeutics," said Dr. Juhienah Khalaf, Ph.D., Director of Chemistry and sub-principal investigator on the project at Inimmune.
  • "By leveraging the drug discovery expertise and resources of Inimmune, PVP researchers will have the opportunity to maximize the potential therapeutic value of their novel adjuvants."

Over $3.7 million in NIH grants will fund research on impacts of climate change on HIV-related health outcomes

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수요일, 10월 18, 2023
WHO, CUNY, Research, UCSB, Graduate Center, CUNY, National Institute of Allergy and Infectious Diseases, Weather, UCSF, Temperature, Population health, Health, Health equity, Science, Public health, Global Climate and Health Alliance, Implementation Science, Climate, NIAID, Icahn School of Medicine at Mount Sinai, HIV, Diabetes, Food, R01, University, Geographic Locator Codes, PEPFAR, Medicine, Risk, HIV/AIDS, Hypertension, Mount Sinai, Health policy, NIH, SIG, Climate change, Area studies, UNAIDS, Drug resistance, Infection, Epidemiology, Pharmaceutical industry, Agriculture, Central Africa

"These climate-related factors likely also increase the risk of poor clinical outcomes among people living with HIV."

Key Points: 
  • "These climate-related factors likely also increase the risk of poor clinical outcomes among people living with HIV."
  • Work on the four-year R01 award will combine data sources uniquely suited to characterize the influence of extreme weather on HIV care outcomes.
  • This, in turn, can inform strategies to help mitigate the impacts of climate change and extreme weather on HIV care outcomes and the trajectory of the HIV pandemic.
  • The team is currently recruiting for a full-time Postdoctoral Fellow to focus on climate and health research, as well as a full-time Project Manager , to join the project team.

Presentations at IDWeek 2023 Highlight Potentially Differentiated Immunogenicity of Gritstone bio’s Next Generation COVID-19 Vaccine

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수요일, 10월 11, 2023
COVID-19, NIAID, National Institute of Allergy and Infectious Diseases, Vaccine, RNA, Immunity, Immunogenicity, Gritstone bio, Group A, Infection, PLWH, HIV, CORAL, Epitope, NAB, Reactogenicity, Messenger, Infectious Disease Clinics of North America, Pharmaceutical industry, Gritstone, Safety

EMERYVILLE, Calif., Oct. 11, 2023 (GLOBE NEWSWIRE) -- October 11, 2023 (GLOBE NEWSWIRE) – Gritstone bio, Inc. (Nasdaq: GRTS), a clinical-stage biotechnology company working to develop the world’s most potent vaccines, today announced the presentation of results from three ongoing Phase 1 studies evaluating its self-amplifying mRNA (samRNA) vaccine candidates against COVID-19 (part of the company’s CORAL program) at IDWeek 2023, occurring October 11-15, 2023, in Boston, MA.

Key Points: 
  • Gritstone will present further follow up data from the CORAL-CEPI and CORAL-BOOST studies (most recent prior presentation in April 2023, press release ).
  • CORAL-BOOST (NCT05148962) is a Phase 1 study evaluating a samRNA-based COVID-19 vaccine candidate containing spike plus other viral targets in older adults ≥60 years of age (N = 40).
  • Broad T cell responses induced against Spike and non-Spike T cell epitopes included in the vaccine.
  • To view Gritstone’s IDWeek 2023 poster presentations, visit ir.gritstonebio.com/investors/events .

Ocugen Mucosal Vaccine Candidate OCU500 Selected by NIH/NIAID Project NextGen for Inclusion in Clinical Trials

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화요일, 10월 10, 2023
COVID-19, NIAID, Nextgen, Vaccine, Public, ChAdOx1, Therapy, Project, Inhalation, Infection, National Institute of Allergy and Infectious Diseases, Vaccination, Bangladesh Technical Education Board, BARDA, Pharmaceutical industry

Ocugen is developing a novel anti-viral mucosal vaccine platform initially targeting COVID-19 and influenza (flu).

Key Points: 
  • Ocugen is developing a novel anti-viral mucosal vaccine platform initially targeting COVID-19 and influenza (flu).
  • NIAID, with funding from Project NextGen, will cover the full cost of the clinical trials, including operations and related analysis.
  • Ocugen will be responsible for providing clinical trial materials and upon completion will have full right of reference to the findings, which Ocugen believes will provide clinical evidence to support the further development of the Company’s lead mucosal vaccine candidate.
  • Ocugen looks forward to this important next step in the development of its novel mucosal vaccine platform and further supporting the Company’s commitment to advancing public health.